Published in Nat Immunol on September 07, 2015
The Growing Complexity of Cancer Cell Response to DNA-Damaging Agents: Caspase 3 Mediates Cell Death or Survival? Int J Mol Sci (2016) 0.94
The Multifaceted Role of Perivascular Macrophages in Tumors. Cancer Cell (2016) 0.84
Subverting misconceptions about radiation therapy. Nat Immunol (2016) 0.81
Subversion of anticancer immunosurveillance by radiotherapy. Nat Immunol (2015) 0.81
Impacts of Ionizing Radiation on the Different Compartments of the Tumor Microenvironment. Front Pharmacol (2016) 0.78
Comparative genomics analysis of mononuclear phagocyte subsets confirms homology between lymphoid tissue-resident and dermal XCR1(+) DCs in mouse and human and distinguishes them from Langerhans cells. J Immunol Methods (2016) 0.77
NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy. Cell Death Differ (2017) 0.75
Reply to: "Subverting misconceptions about radiation therapy". Nat Immunol (2016) 0.75
Platelet activating factor-induced expression of p21 is correlated with histone acetylation. Sci Rep (2017) 0.75
Radiotherapy and immunotherapy: a beneficial liaison? Nat Rev Clin Oncol (2017) 0.75
Exogenous remodeling of lung resident macrophages protects against infectious consequences of bone marrow-suppressive chemotherapy. Proc Natl Acad Sci U S A (2016) 0.75
Immunosuppressive cell death in cancer. Nat Rev Immunol (2017) 0.75
Intercellular Communication of Tumor Cells and Immune Cells after Exposure to Different Ionizing Radiation Qualities. Front Immunol (2017) 0.75
Adipose-derived mesenchymal stem cells from patients with atherosclerotic renovascular disease have increased DNA damage and reduced angiogenesis that can be modified by hypoxia. Stem Cell Res Ther (2016) 0.75
Using machine learning algorithms to identify genes essential for cell survival. BMC Bioinformatics (2017) 0.75
Immune recognition of irradiated cancer cells. Immunol Rev (2017) 0.75
Modulating Both Tumor Cell Death and Innate Immunity Is Essential for Improving Radiation Therapy Effectiveness. Front Immunol (2017) 0.75
Ontogeny and function of murine epidermal Langerhans cells. Nat Immunol (2017) 0.75
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med (2012) 52.99
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med (2007) 13.90
p21 in cancer: intricate networks and multiple activities. Nat Rev Cancer (2009) 9.21
Langerhans cells renew in the skin throughout life under steady-state conditions. Nat Immunol (2002) 7.03
Oncology meets immunology: the cancer-immunity cycle. Immunity (2013) 5.60
Mechanisms of suppression by suppressor T cells. Nat Immunol (2005) 5.52
CCR7 governs skin dendritic cell migration under inflammatory and steady-state conditions. Immunity (2004) 5.48
Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment. Blood (2009) 5.21
The comet assay: a method to measure DNA damage in individual cells. Nat Protoc (2006) 5.11
The origin and development of nonlymphoid tissue CD103+ DCs. J Exp Med (2009) 4.79
The role of the cyclin-dependent kinase inhibitor p21 in apoptosis. Mol Cancer Ther (2002) 4.73
Deciphering the transcriptional network of the dendritic cell lineage. Nat Immunol (2012) 4.17
Origin, homeostasis and function of Langerhans cells and other langerin-expressing dendritic cells. Nat Rev Immunol (2008) 4.17
Strategies to improve radiotherapy with targeted drugs. Nat Rev Cancer (2011) 4.08
Dendritic cell and macrophage heterogeneity in vivo. Immunity (2011) 3.41
Spinning molecular immunology into successful immunotherapy. Nat Rev Immunol (2002) 3.37
Gamma-H2AX - a novel biomarker for DNA double-strand breaks. In Vivo (2008) 3.13
Combining radiotherapy and cancer immunotherapy: a paradigm shift. J Natl Cancer Inst (2013) 3.07
Low-dose irradiation programs macrophage differentiation to an iNOS⁺/M1 phenotype that orchestrates effective T cell immunotherapy. Cancer Cell (2013) 2.89
Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny. Nat Rev Immunol (2014) 2.82
p21(WAF1/Cip1): more than a break to the cell cycle? Biochim Biophys Acta (2000) 2.81
The efficacy of radiotherapy relies upon induction of type i interferon-dependent innate and adaptive immunity. Cancer Res (2011) 2.60
P53 and radiation responses. Oncogene (2003) 2.52
Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells. Nat Immunol (2009) 2.32
STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors. Immunity (2014) 2.28
B16 as a mouse model for human melanoma. Curr Protoc Immunol (2001) 1.80
DNA-damage response in tissue-specific and cancer stem cells. Cell Stem Cell (2011) 1.67
The mechanism of action of radiosensitization of conventional chemotherapeutic agents. Semin Radiat Oncol (2003) 1.66
Transient regulatory T cell ablation deters oncogene-driven breast cancer and enhances radiotherapy. J Exp Med (2013) 1.47
An optimized method for measurement of gamma-H2AX in blood mononuclear and cultured cells. Nat Protoc (2008) 1.44
Radiation-induced equilibrium is a balance between tumor cell proliferation and T cell-mediated killing. J Immunol (2013) 1.44
The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development. Nat Med (2000) 1.43
Prevention of UV radiation-induced immunosuppression by IL-12 is dependent on DNA repair. J Exp Med (2005) 1.39
Radiation enhances regulatory T cell representation. Int J Radiat Oncol Biol Phys (2010) 1.39
The role of antigen-presenting cells in triggering graft-versus-host disease and graft-versus-leukemia. Blood (2007) 1.37
Two distinct types of Langerhans cells populate the skin during steady state and inflammation. Immunity (2012) 1.36
New paradigms and future challenges in radiation oncology: an update of biological targets and technology. Sci Transl Med (2013) 1.35
Specialized role of migratory dendritic cells in peripheral tolerance induction. J Clin Invest (2013) 1.33
Loss of p21 CDKN1A impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence. Cell Cycle (2009) 1.24
Langerhans cells facilitate epithelial DNA damage and squamous cell carcinoma. Science (2012) 1.24
p53-dependent apoptosis or growth arrest induced by different forms of radiation in U2OS cells: p21WAF1/CIP1 repression in UV induced apoptosis. Oncogene (1999) 1.23
Statistics of the Comet assay: a key to discriminate between genotoxic effects. Mutagenesis (2003) 1.23
Langerhans cells are required for UVR-induced immunosuppression. J Invest Dermatol (2010) 1.16
bcl-xL is critical for dendritic cell survival in vivo. J Immunol (2004) 1.13
A p53 and apoptotic independent role for p21waf1 in tumour response to radiation therapy. Oncogene (1999) 1.04
Exposure to ionizing radiation induces the migration of cutaneous dendritic cells by a CCR7-dependent mechanism. J Immunol (2012) 0.97
Migration of skin dendritic cells in response to ionizing radiation exposure. Radiat Res (2009) 0.97
Loss of p21Waf1/Cip1 sensitizes tumors to radiation by an apoptosis-independent mechanism. Cancer Res (1997) 0.93
p21WAF1 expression is associated with improved survival after adjuvant chemoradiation for pancreatic cancer. Surgery (2000) 0.87
The ataxia telangiectasia mutated kinase pathway regulates IL-23 expression by human dendritic cells. J Immunol (2013) 0.86