Published in Sci Rep on September 08, 2015
Targeting mitotic pathways for endocrine-related cancer therapeutics. Endocr Relat Cancer (2017) 0.75
Surfing the p53 network. Nature (2000) 35.36
Cancer. p53, guardian of the genome. Nature (1992) 16.36
Cancer/testis antigens, gametogenesis and cancer. Nat Rev Cancer (2005) 9.46
The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell (2006) 8.44
Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor. Science (2002) 8.41
The first 30 years of p53: growing ever more complex. Nat Rev Cancer (2009) 8.00
Endonuclease G is an apoptotic DNase when released from mitochondria. Nature (2001) 6.20
A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell (2009) 6.03
When mutants gain new powers: news from the mutant p53 field. Nat Rev Cancer (2009) 5.86
A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev (2004) 5.23
p53 mutations in cancer. Nat Cell Biol (2013) 5.18
p53 and metabolism. Nat Rev Cancer (2009) 5.05
A MicroRNA targeting dicer for metastasis control. Cell (2010) 4.81
Mutant p53 drives invasion by promoting integrin recycling. Cell (2009) 4.75
Mutant p53 in cancer: new functions and therapeutic opportunities. Cancer Cell (2014) 3.68
Primary microcephaly: do all roads lead to Rome? Trends Genet (2009) 3.60
TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs. Nature (2010) 3.37
Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo. Proc Natl Acad Sci U S A (2005) 3.24
Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1. Dev Cell (2007) 3.06
A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1. Nat Cell Biol (2004) 3.04
Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. Mol Ther (2009) 2.92
MicroRNAs in the p53 network: micromanagement of tumour suppression. Nat Rev Cancer (2012) 2.78
p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug. Nat Cell Biol (2009) 2.35
Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer. Proc Natl Acad Sci U S A (2012) 1.97
Senescence and aging: the critical roles of p53. Oncogene (2013) 1.90
Primary autosomal recessive microcephaly: homozygosity mapping of MCPH4 to chromosome 15. Am J Hum Genet (1999) 1.74
BUB1 mediation of caspase-independent mitotic death determines cell fate. J Cell Biol (2007) 1.52
In vivo monitoring of tumor relapse and metastasis using bioluminescent PC-3M-luc-C6 cells in murine models of human prostate cancer. Clin Exp Metastasis (2003) 1.37
Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore. J Cell Biol (2012) 1.26
KI motifs of human Knl1 enhance assembly of comprehensive spindle checkpoint complexes around MELT repeats. Curr Biol (2013) 1.25
p53 modulates acquired resistance to EGFR inhibitors and radiation. Cancer Res (2011) 1.17
A cloning method for caspase substrates that uses the yeast two-hybrid system: cloning of the antiapoptotic gene gelsolin. Proc Natl Acad Sci U S A (1998) 1.11
The p53 tumor suppressor protein regulates hematopoietic stem cell fate. J Cell Physiol (2011) 1.08
p53 enhances gefitinib-induced growth inhibition and apoptosis by regulation of Fas in non-small cell lung cancer. Cancer Res (2007) 1.06
Kinetochore KMN network gene CASC5 mutated in primary microcephaly. Hum Mol Genet (2012) 1.03
Defects in p21WAF1/CIP1, Rb, and c-myc signaling in phorbol ester-resistant cancer cells. Cancer Res (1997) 1.02
p53 and autophagy in cancer: guardian of the genome meets guardian of the proteome. Eur J Cancer (2010) 0.99
Frequent expression of new cancer/testis gene D40/AF15q14 in lung cancers of smokers. Br J Cancer (2002) 0.98
An epidermal growth factor inhibitor, Gefitinib, induces apoptosis through a p53-dependent upregulation of pro-apoptotic molecules and downregulation of anti-apoptotic molecules in human lung adenocarcinoma A549 cells. Eur J Pharmacol (2008) 0.97
Caspase-independent mitotic death (CIMD). Cell Cycle (2008) 0.97
AF15q14, a novel partner gene fused to the MLL gene in an acute myeloid leukaemia with a t(11;15)(q23;q14). Oncogene (2000) 0.94
KNL1: bringing order to the kinetochore. Chromosoma (2013) 0.91
p53-mediated activation of the mitochondrial protease HtrA2/Omi prevents cell invasion. J Cell Biol (2014) 0.83
P53 and PTEN expression contribute to the inhibition of EGFR downstream signaling pathway by cetuximab. Cancer Gene Ther (2009) 0.83
Atelocollagen-mediated systemic DDS for nucleic acid medicines. Ann N Y Acad Sci (2006) 0.82
Chromosomal assignment of a novel human gene D40. Nucleic Acids Symp Ser (1999) 0.77
The protein encoded by cancer/testis gene D40/AF15q14 is localized in spermatocytes, acrosomes of spermatids and ejaculated spermatozoa. Reproduction (2004) 0.77
Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper. J Extracell Vesicles (2015) 1.30
Extracellular vesicle transfer of cancer pathogenic components. Cancer Sci (2016) 1.01
The clinical relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 network in chemoresistant non-small-cell lung cancer. Mol Ther (2015) 0.98
RPN2 Gene Confers Osteosarcoma Cell Malignant Phenotypes and Determines Clinical Prognosis. Mol Ther Nucleic Acids (2014) 0.79
Exosomal miRNAs from Peritoneum Lavage Fluid as Potential Prognostic Biomarkers of Peritoneal Metastasis in Gastric Cancer. PLoS One (2015) 0.78
Identification and Characterization of CXCR4-Positive Gastric Cancer Stem Cells. PLoS One (2015) 0.78
Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells. Mol Ther (2016) 0.77
Clinical significance of circulating miR-25-3p as a novel diagnostic and prognostic biomarker in osteosarcoma. Oncotarget (2017) 0.77
Global, cancer-specific microRNA cluster hypomethylation was functionally associated with the development of non-B non-C hepatocellular carcinoma. Mol Cancer (2016) 0.75
Extracellular vesicles in smoking-related lung diseases. Oncotarget (2015) 0.75
Transplantation of Thy1(+) Cells Accelerates Liver Regeneration by Enhancing the Growth of Small Hepatocyte-like Progenitor Cells via IL17RB Signaling. Stem Cells (2016) 0.75
The expression and clinical significance of ribophorin II (RPN2) in human breast cancer. Pathol Int (2015) 0.75
Circulating MicroRNA-92b-3p as a Novel Biomarker for Monitoring of Synovial Sarcoma. Sci Rep (2017) 0.75
Extracellular vesicles as trans-genomic agents: emerging roles in disease and evolution. Cancer Sci (2017) 0.75
International Society for Extracellular Vesicles: Second Annual Meeting, 17-20 April 2013, Boston, MA (ISEV 2013). J Extracell Vesicles (2013) 0.75
MicroRNA-125b expression and intrahepatic metastasis are predictors for early recurrence after hepatocellular carcinoma resection. Hepatol Res (2017) 0.75
Concomitant Evaluation of a Panel of Exosome Proteins and MiRs for Qualification of Cultured Human Corneal Endothelial Cells. Invest Ophthalmol Vis Sci (2016) 0.75