Published in Oncotarget on October 20, 2015
Ultraconserved long non-coding RNA uc.63 in breast cancer. Oncotarget (2016) 0.76
Metabolic pathways regulated by TAp73 in response to oxidative stress. Oncotarget (2016) 0.76
The p53 family orchestrates the regulation of metabolism: physiological regulation and implications for cancer therapy. Br J Cancer (2016) 0.75
Autophagy in the pathogenesis of disease. Cell (2008) 34.68
The role of autophagy during the early neonatal starvation period. Nature (2004) 22.40
Autophagy in immunity and inflammation. Nature (2011) 11.16
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell (1997) 7.27
Hormone-fuel interrelationships during fasting. J Clin Invest (1966) 6.44
p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours. Nature (2000) 5.83
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes Dev (2008) 4.85
How cancer metabolism is tuned for proliferation and vulnerable to disruption. Nature (2012) 3.77
p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase. Nat Cell Biol (2011) 3.70
p73: Friend or foe in tumorigenesis. Nat Rev Cancer (2002) 3.30
Autophagy in human health and disease. N Engl J Med (2013) 2.73
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death Differ (2014) 2.66
The p53 family: guardians of maternal reproduction. Nat Rev Mol Cell Biol (2011) 2.13
Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway. Genes Dev (2010) 2.06
TIGAR is required for efficient intestinal regeneration and tumorigenesis. Dev Cell (2013) 2.03
Fasting: molecular mechanisms and clinical applications. Cell Metab (2014) 1.94
Itch: a HECT-type E3 ligase regulating immunity, skin and cancer. Cell Death Differ (2008) 1.77
The impact of p53 and p73 on aneuploidy and cancer. Trends Cell Biol (2008) 1.76
Serine and glycine metabolism in cancer. Trends Biochem Sci (2014) 1.70
TAp73 enhances the pentose phosphate pathway and supports cell proliferation. Nat Cell Biol (2013) 1.61
microRNA-34a regulates neurite outgrowth, spinal morphology, and function. Proc Natl Acad Sci U S A (2011) 1.60
Neuronal differentiation by TAp73 is mediated by microRNA-34a regulation of synaptic protein targets. Proc Natl Acad Sci U S A (2011) 1.58
Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling. Cell Death Differ (2013) 1.49
TAp73 depletion accelerates aging through metabolic dysregulation. Genes Dev (2012) 1.45
Regulation of autophagy by the Rab GTPase network. Cell Death Differ (2014) 1.37
Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition. Oncotarget (2014) 1.37
MicroRNA-25 regulates chemoresistance-associated autophagy in breast cancer cells, a process modulated by the natural autophagy inducer isoliquiritigenin. Oncotarget (2014) 1.36
PI3K/Akt/mTOR pathway inhibitors enhance radiosensitivity in radioresistant prostate cancer cells through inducing apoptosis, reducing autophagy, suppressing NHEJ and HR repair pathways. Cell Death Dis (2014) 1.36
p73 in Cancer. Genes Cancer (2011) 1.33
Role of p73 in malignancy: tumor suppressor or oncogene? Cell Death Differ (2002) 1.19
Roles for p53 and p73 during oligodendrocyte development. Development (2004) 1.18
High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy. Cell Death Dis (2014) 1.12
The jury is in: p73 is a tumor suppressor after all. Genes Dev (2008) 1.12
Regulation of p73 activity by post-translational modifications. Cell Death Dis (2012) 1.12
p63 and p73 coordinate p53 function to determine the balance between survival, cell death, and senescence in adult neural precursor cells. Cell Death Differ (2014) 1.11
The antiapoptotic DeltaNp73 is degraded in a c-Jun-dependent manner upon genotoxic stress through the antizyme-mediated pathway. Proc Natl Acad Sci U S A (2010) 1.09
Down-regulation of autophagy-related protein 5 (ATG5) contributes to the pathogenesis of early-stage cutaneous melanoma. Sci Transl Med (2013) 1.09
Regulation of autophagy by polyphenolic compounds as a potential therapeutic strategy for cancer. Cell Death Dis (2014) 1.08
Autophagy and genomic integrity. Cell Death Differ (2013) 1.07
p73 regulates serine biosynthesis in cancer. Oncogene (2013) 1.06
The Hippo pathway kinase Lats2 prevents DNA damage-induced apoptosis through inhibition of the tyrosine kinase c-Abl. Cell Death Differ (2013) 1.04
Cooperative role of RanBP9 and P73 in mitochondria-mediated apoptosis. Cell Death Dis (2013) 1.01
The p53 family and the hypoxia-inducible factors (HIFs): determinants of cancer progression. Trends Biochem Sci (2015) 1.00
Metabolic effect of TAp63α: enhanced glycolysis and pentose phosphate pathway, resulting in increased antioxidant defense. Oncotarget (2014) 0.97
p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene. Cell Death Differ (2013) 0.97
A sphingosine kinase inhibitor combined with temozolomide induces glioblastoma cell death through accumulation of dihydrosphingosine and dihydroceramide, endoplasmic reticulum stress and autophagy. Cell Death Dis (2014) 0.96
CHOP mediates ASPP2-induced autophagic apoptosis in hepatoma cells by releasing Beclin-1 from Bcl-2 and inducing nuclear translocation of Bcl-2. Cell Death Dis (2014) 0.96
Regulatory feedback loop between TP73 and TRIM32. Cell Death Dis (2013) 0.95
Analysis of the oligomeric state and transactivation potential of TAp73α. Cell Death Differ (2013) 0.94
Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly. Cell Death Differ (2014) 0.92
p73alpha isoforms drive opposite transcriptional and post-transcriptional regulation of MYCN expression in neuroblastoma cells. Nucleic Acids Res (2008) 0.92
Bortezomib enhances cancer cell death by blocking the autophagic flux through stimulating ERK phosphorylation. Cell Death Dis (2014) 0.92
Transcriptional regulation of the p73 gene by Nrf-2 and promoter CpG methylation in human breast cancer. Oncotarget (2014) 0.91
TAp73 promotes anti-senescence-anabolism not proliferation. Aging (Albany NY) (2014) 0.91
Autophagy promotes paclitaxel resistance of cervical cancer cells: involvement of Warburg effect activated hypoxia-induced factor 1-α-mediated signaling. Cell Death Dis (2014) 0.90
Autophagy is required for zebrafish caudal fin regeneration. Cell Death Differ (2013) 0.90
ROS inhibit autophagy by downregulating ULK1 mediated by the phosphorylation of p53 in selenite-treated NB4 cells. Cell Death Dis (2014) 0.90
The autophagy regulators Ambra1 and Beclin 1 are required for adult neurogenesis in the brain subventricular zone. Cell Death Dis (2014) 0.89
ATG5 can regulate p53 expression and activation. Cell Death Dis (2014) 0.89
TAp73 promotes anabolism. Oncotarget (2014) 0.89
ΔNp63 regulates select routes of reprogramming via multiple mechanisms. Cell Death Differ (2013) 0.89
RITA can induce cell death in p53-defective cells independently of p53 function via activation of JNK/SAPK and p38. Cell Death Dis (2014) 0.88
Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells. Oncotarget (2014) 0.88
Targeting autophagy as a potential therapeutic approach for melanoma therapy. Semin Cancer Biol (2013) 0.88
Recognition of p63 by the E3 ligase ITCH: Effect of an ectodermal dysplasia mutant. Cell Cycle (2010) 0.87
Suppression of acetylpolyamine oxidase by selected AP-1 members regulates DNp73 abundance: mechanistic insights for overcoming DNp73-mediated resistance to chemotherapeutic drugs. Cell Death Differ (2014) 0.87
The LRRK2 inhibitor GSK2578215A induces protective autophagy in SH-SY5Y cells: involvement of Drp-1-mediated mitochondrial fission and mitochondrial-derived ROS signaling. Cell Death Dis (2014) 0.86
Control of ketogenesis from amino acids. IV. Tissue specificity in oxidation of leucine, tyrosine, and lysine. J Biochem (1976) 0.85
The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells. Oncotarget (2014) 0.85
Role of AMP-activated protein kinase in cross-talk between apoptosis and autophagy in human colon cancer. Cell Death Dis (2014) 0.85
Blocking autophagy enhanced cytotoxicity induced by recombinant human arginase in triple-negative breast cancer cells. Cell Death Dis (2014) 0.84
Recognition mechanism of p63 by the E3 ligase Itch: novel strategy in the study and inhibition of this interaction. Cell Cycle (2012) 0.84
p63 threonine phosphorylation signals the interaction with the WW domain of the E3 ligase Itch. Cell Cycle (2014) 0.84
Analysis of TAp73-dependent signaling via omics technologies. J Proteome Res (2013) 0.83
TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses. Cell Death Differ (2012) 0.83
AMPK couples p73 with p53 in cell fate decision. Cell Death Differ (2014) 0.83
TAp73β-mediated suppression of cell migration requires p57Kip2 control of actin cytoskeleton dynamics. Oncotarget (2013) 0.82
Relative expression of TAp73 and ΔNp73 isoforms. Aging (Albany NY) (2012) 0.82
p63 transcriptionally regulates the expression of matrix metallopeptidase 13. Oncotarget (2014) 0.82
A novel androstenedione derivative induces ROS-mediated autophagy and attenuates drug resistance in osteosarcoma by inhibiting macrophage migration inhibitory factor (MIF). Cell Death Dis (2014) 0.82
JNK-NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stress. Cell Death Dis (2014) 0.81
Dynamic involvement of ATG5 in cellular stress responses. Cell Death Dis (2014) 0.81
∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites. Oncotarget (2014) 0.81
p53-induced autophagy and senescence. Oncotarget (2015) 0.81
ARHI (DIRAS3) induces autophagy in ovarian cancer cells by downregulating the epidermal growth factor receptor, inhibiting PI3K and Ras/MAP signaling and activating the FOXo3a-mediated induction of Rab7. Cell Death Differ (2014) 0.81
MDM2 mediates p73 ubiquitination: a new molecular mechanism for suppression of p73 function. Oncotarget (2015) 0.80
Autophagy and mitochondrial alterations in human retinal pigment epithelial cells induced by ethanol: implications of 4-hydroxy-nonenal. Cell Death Dis (2014) 0.80
Autophagic program is regulated by miR-325. Cell Death Differ (2014) 0.80
Eradication of metastatic melanoma through cooperative expression of RNA-based HDAC1 inhibitor and p73 by oncolytic adenovirus. Oncotarget (2014) 0.80
Autophagy protects from liver injury. Cell Death Differ (2013) 0.79
Beclin-1-independent autophagy positively regulates internal ribosomal entry site-dependent translation of hypoxia-inducible factor 1α under nutrient deprivation. Oncotarget (2014) 0.79
Autophagic cell death RIPs into tumors. Cell Death Differ (2013) 0.77
The 6th International p63/p73 Workshop: the C(ancer) and D(evelopmental) roles of p63 and p73. Cell Death Differ (2014) 0.75
Autophagy in malignant transformation and cancer progression. EMBO J (2015) 2.67
Comparison of different biopsy forceps models for tissue sampling in eosinophilic esophagitis. Endoscopy (2016) 1.40
NET formation can occur independently of RIPK3 and MLKL signaling. Eur J Immunol (2015) 1.17
Therapeutic approaches to patients with hypereosinophilic syndromes. Semin Hematol (2012) 0.92
Rapid Sequestration of Leishmania mexicana by Neutrophils Contributes to the Development of Chronic Lesion. PLoS Pathog (2015) 0.89
Precision medicine in patients with allergic diseases: Airway diseases and atopic dermatitis-PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma & Immunology. J Allergy Clin Immunol (2016) 0.84
Eosinophilic bioactivities in severe asthma. World Allergy Organ J (2016) 0.82
Cellular and molecular immunologic mechanisms in patients with atopic dermatitis. J Allergy Clin Immunol (2016) 0.82
Molecular definitions of autophagy and related processes. EMBO J (2017) 0.79
RhoH is a negative regulator of eosinophilopoiesis. Cell Death Differ (2016) 0.78
The expanding role of immunopharmacology: IUPHAR Review 16. Br J Pharmacol (2015) 0.77
A novel link between p53 and ROS. Cell Cycle (2012) 0.75
IVIG regulates the survival of human but not mouse neutrophils. Sci Rep (2017) 0.75
Identification of Novel Death-Associated Protein Kinase 2 Interaction Partners by Proteomic Screening Coupled with Bimolecular Fluorescence Complementation. Mol Cell Biol (2015) 0.75
Food allergy in EAACI journals (2016). Pediatr Allergy Immunol (2017) 0.75
Eosinophils as putative therapeutic targets in bullous pemphigoid. Exp Dermatol (2017) 0.75
ROS and glutathionylation balance cytoskeletal dynamics in neutrophil extracellular trap formation. J Cell Biol (2017) 0.75
Immunopathogenesis of eosinophilic esophagitis. Dig Dis (2014) 0.75
Neither eosinophils nor neutrophils require ATG5-dependent autophagy for extracellular DNA trap formation. Immunology (2017) 0.75