Published in Cancer Cell Int on October 13, 2015
Strategies for monitoring and combating resistance to combination kinase inhibitors for cancer therapy. Genome Med (2017) 0.75
Identification of key genes associated with cervical cancer by comprehensive analysis of transcriptome microarray and methylation microarray. Oncol Lett (2016) 0.75
Pan-cancer analysis of frequent DNA co-methylation patterns reveals consistent epigenetic landscape changes in multiple cancers. BMC Genomics (2017) 0.75
A polycomb-mediated epigenetic field defect precedes invasive cervical carcinoma. Oncotarget (2016) 0.75
Identification of the metabolic alterations associated with the multidrug resistant phenotype in cancer and their intercellular transfer mediated by extracellular vesicles. Sci Rep (2017) 0.75
The fundamental role of epigenetic events in cancer. Nat Rev Genet (2002) 30.05
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet (2003) 25.57
A decade of exploring the cancer epigenome - biological and translational implications. Nat Rev Cancer (2011) 11.33
Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol (2003) 9.30
Perceptions of epigenetics. Nature (2007) 8.43
Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome. Environ Health Perspect (2006) 4.46
Isolation of multipotent mesenchymal stem cells from umbilical cord blood. Blood (2003) 4.09
DNA hypomethylation in cancer cells. Epigenomics (2009) 3.71
DNA methylation and cancer. Adv Genet (2010) 3.50
In utero effects. In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism. Science (2014) 3.07
Mapping geographic zones of cancer risk with epigenetic biomarkers in normal breast tissue. Clin Cancer Res (2006) 2.70
DNA methylation dynamics of the human preimplantation embryo. Nature (2014) 2.55
Epigenetic gene regulation: linking early developmental environment to adult disease. Reprod Toxicol (2006) 2.49
Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities. BMC Cancer (2008) 2.47
Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers. Proc Natl Acad Sci U S A (2009) 1.98
Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer. Cancer Res (2004) 1.97
DNA methylation and cellular reprogramming. Trends Cell Biol (2010) 1.77
The acquisition of hMLH1 methylation in plasma DNA after chemotherapy predicts poor survival for ovarian cancer patients. Clin Cancer Res (2004) 1.65
Targeting DNA methylation for epigenetic therapy. Trends Pharmacol Sci (2010) 1.61
Differential DNA hypermethylation and hypomethylation signatures in colorectal cancer. Hum Mol Genet (2004) 1.60
DNA methylation in mammals. Cold Spring Harb Perspect Biol (2014) 1.57
DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos. Genes Dev (2014) 1.55
Genomewide DNA methylation analysis reveals novel targets for drug development in mantle cell lymphoma. Blood (2010) 1.53
DNA methylation of the Trip10 promoter accelerates mesenchymal stem cell lineage determination. Biochem Biophys Res Commun (2010) 1.52
Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation. Cancer Res (2003) 1.32
DNA methylation and methylcytosine oxidation in cell fate decisions. Curr Opin Cell Biol (2013) 1.24
Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance. J Pathol (2010) 1.24
Promoter methylation of p16, DAPK, CDH1, and TIMP-3 genes in cervical cancer: correlation with clinicopathologic characteristics. Int J Gynecol Cancer (2006) 1.19
Differential methylation hybridization: profiling DNA methylation with a high-density CpG island microarray. Methods Mol Biol (2009) 1.15
Targeted methylation of two tumor suppressor genes is sufficient to transform mesenchymal stem cells into cancer stem/initiating cells. Cancer Res (2011) 1.15
Promoter hypermethylation of the death-associated protein kinase gene in breast cancer is associated with the invasive lobular subtype. Cancer Res (2002) 1.09
Methylated TMS1 and DAPK genes predict prognosis and response to chemotherapy in gastric cancer. Int J Cancer (2008) 1.04
TRAIL death receptors as tumor suppressors and drug targets. Cell Cycle (2008) 1.01
Maternal exposure to diethylstilbestrol during pregnancy and increased breast cancer risk in daughters. Breast Cancer Res (2014) 0.99
Genome-wide DNA methylation assay reveals novel candidate biomarker genes in cervical cancer. Epigenetics (2013) 0.97
Hypermethylation of the death-associated protein kinase promoter attenuates the sensitivity to TRAIL-induced apoptosis in human non-small cell lung cancer cells. Mol Cancer Res (2004) 0.97
S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth. Mol Cancer Ther (2010) 0.94
Targeted methylation of CMV and E1A viral promoters. Biochem Biophys Res Commun (2010) 0.94
High frequency of DAP-kinase gene promoter methylation in colorectal cancer specimens and its identification in serum. Cancer Lett (2003) 0.91
Preprocessing differential methylation hybridization microarray data. BioData Min (2011) 0.89
Decitabine, a DNA methyltransferase inhibitor, reduces P-glycoprotein mRNA and protein expressions and increases drug sensitivity in drug-resistant MOLT4 and Jurkat cell lines. Anticancer Res (2012) 0.87
The rise of DNA methylation and the importance of chromatin on multidrug resistance in cancer. Exp Cell Res (2003) 0.87
Quantitative DNA methylation analysis of candidate genes in cervical cancer. PLoS One (2015) 0.86
Excavating relics of DNA methylation changes during the development of neoplasia. Semin Cancer Biol (2009) 0.84
Environmental toxicants--induced epigenetic alterations and their reversers. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev (2012) 0.84
Mechanistic basis of a combination D-penicillamine and platinum drugs synergistically inhibits tumor growth in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo. Biochem Pharmacol (2015) 0.83
Reduced BMP6 expression by DNA methylation contributes to EMT and drug resistance in breast cancer cells. Oncol Rep (2014) 0.81
Alteration of gene expression and DNA methylation in drug-resistant gastric cancer. Oncol Rep (2014) 0.81
Identification of novel DNA methylation inhibitors via a two-component reporter gene system. J Biomed Sci (2011) 0.80
DNA methylation-independent reversion of gemcitabine resistance by hydralazine in cervical cancer cells. PLoS One (2012) 0.80
[Aberrant DNA methylation and drug resistance of tumor cells]. Yi Chuan (2014) 0.79
[Correction of DNA methylation disorder as a possible way to modulation of malignant cells drug resistance]. Ukr Biokhim Zh (1999) (2007) 0.77