Published in Zhongguo Zhong Yao Za Zhi on June 01, 2015
Global quantification of mammalian gene expression control. Nature (2011) 22.36
High-quality binary protein interaction map of the yeast interactome network. Science (2008) 10.65
The Genomes of Oryza sativa: a history of duplications. PLoS Biol (2005) 7.67
Evidence for substantial fine-scale variation in recombination rates across the human genome. Nat Genet (2004) 6.99
miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades. Nucleic Acids Res (2011) 5.83
The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30
Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO. Nature (2003) 3.96
HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo. EMBO J (2003) 3.96
Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice. J Clin Invest (2009) 3.45
Combination targeted therapy with sorafenib and bevacizumab results in enhanced toxicity and antitumor activity. J Clin Oncol (2008) 3.32
Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally. Mol Cell Biol (2008) 2.85
Mapping translocation breakpoints by next-generation sequencing. Genome Res (2008) 2.73
Enhanced sarcoplasmic reticulum Ca2+ leak and increased Na+-Ca2+ exchanger function underlie delayed afterdepolarizations in patients with chronic atrial fibrillation. Circulation (2012) 2.58
The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes. Nat Immunol (2010) 2.53
Ablation of beta1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation. J Cell Biol (2005) 2.33
Hepatic sinusoidal obstruction syndrome associated with consumption of Gynura segetum. J Hepatol (2010) 2.33
A protein domain-based interactome network for C. elegans early embryogenesis. Cell (2008) 2.23
Asymmetric dimethylarginine in response to recombinant tissue-type plasminogen activator and erythropoietin in acute stroke. Stroke (2013) 2.07
Artificial muscles from fishing line and sewing thread. Science (2014) 2.04
Periodontal ligament stem cell-mediated treatment for periodontitis in miniature swine. Stem Cells (2008) 1.99
Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling. Am J Pathol (2008) 1.97
Smad3 signaling critically regulates fibroblast phenotype and function in healing myocardial infarction. Circ Res (2010) 1.94
Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction. J Am Coll Cardiol (2008) 1.90
Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. Dev Cell (2011) 1.89
A phase II clinical trial of sorafenib in androgen-independent prostate cancer. Clin Cancer Res (2008) 1.87
Downregulation of transcription factor Oct4 induces an epithelial-to-mesenchymal transition via enhancement of Ca2+ influx in breast cancer cells. Biochem Biophys Res Commun (2011) 1.82
Large-scale sorting of C. elegans embryos reveals the dynamics of small RNA expression. Nat Methods (2009) 1.82
Electrically, chemically, and photonically powered torsional and tensile actuation of hybrid carbon nanotube yarn muscles. Science (2012) 1.80
Endogenous thrombospondin 1 protects the pressure-overloaded myocardium by modulating fibroblast phenotype and matrix metabolism. Hypertension (2011) 1.79
Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA. Cell Res (2008) 1.78
Plasma microRNAs, miR-223, miR-21 and miR-218, as novel potential biomarkers for gastric cancer detection. PLoS One (2012) 1.70
OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia. Hepatology (2005) 1.69
A novel retinoic acid receptor beta isoform and retinoid resistance in lung carcinogenesis. J Natl Cancer Inst (2005) 1.67
Ribozyme catalysis of metabolism in the RNA world. Chem Biodivers (2007) 1.66
Genome-wide coactivation analysis of PGC-1alpha identifies BAF60a as a regulator of hepatic lipid metabolism. Cell Metab (2008) 1.65
Findings of perinatal ocular examination performed on 3573, healthy full-term newborns. Br J Ophthalmol (2013) 1.64
CaMKII inhibition rescues proarrhythmic phenotypes in the model of human ankyrin-B syndrome. Heart Rhythm (2012) 1.63
Novel genetic variants contributing to left ventricular hypertrophy: the HyperGEN study. J Hypertens (2009) 1.61
Mutations of the EPHA2 receptor tyrosine kinase gene cause autosomal dominant congenital cataract. Hum Mutat (2009) 1.60
Comprehensive survey of human brain microRNA by deep sequencing. BMC Genomics (2010) 1.59
LncRNAs expression signatures of renal clear cell carcinoma revealed by microarray. PLoS One (2012) 1.59
Involvement of human natural killer cells in asthma pathogenesis: natural killer 2 cells in type 2 cytokine predominance. J Allergy Clin Immunol (2005) 1.59
Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility. Proc Natl Acad Sci U S A (2013) 1.57
MicroRNA-driven developmental remodeling in the brain distinguishes humans from other primates. PLoS Biol (2011) 1.57
A self-assembled DNA nanostructure-amplified quartz crystal microbalance with dissipation biosensing platform for nucleic acids. Chem Commun (Camb) (2012) 1.56
Widespread expression of piRNA-like molecules in somatic tissues. Nucleic Acids Res (2011) 1.56
SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells. PLoS One (2012) 1.55
The hydrogen sulfide donor NaHS promotes angiogenesis in a rat model of hind limb ischemia. Antioxid Redox Signal (2010) 1.54
Paired-end sequencing of Fosmid libraries by Illumina. Genome Res (2012) 1.52
Toll-like receptor 3 is an essential component of the innate stress response in virus-induced cardiac injury. Am J Physiol Heart Circ Physiol (2006) 1.50
A positive autoregulatory loop of LMP1 expression and STAT activation in epithelial cells latently infected with Epstein-Barr virus. J Virol (2003) 1.49
SOX2 promotes tumorigenesis and increases the anti-apoptotic property of human prostate cancer cell. J Mol Cell Biol (2011) 1.48
Regulation of alternative replication bypass pathways at stalled replication forks and its effects on genome stability: a yeast model. Mutat Res (2003) 1.46
Characterization of the inflammatory and fibrotic response in a mouse model of cardiac pressure overload. Histochem Cell Biol (2008) 1.45
Ideal cardiovascular health metrics and the risks of ischemic and intracerebral hemorrhagic stroke. Stroke (2013) 1.45
Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-кB mediated matrix metalloproteinase-1 gene regulation. Breast Cancer Res (2014) 1.44
A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice. Proc Natl Acad Sci U S A (2007) 1.43
Activation of the receptor for advanced glycation end products (RAGE) exacerbates experimental autoimmune myasthenia gravis symptoms. Clin Immunol (2011) 1.42
Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A. J Cell Biol (2005) 1.41
Gene expression differences in mice divergently selected for methamphetamine sensitivity. Mamm Genome (2005) 1.41
Role of RyR2 phosphorylation at S2814 during heart failure progression. Circ Res (2012) 1.41
Spectrotemporal receptive fields in the inferior colliculus revealing selectivity for spectral motion in conspecific vocalizations. J Neurosci (2007) 1.40
Simvastatin suppresses the proangiogenic microenvironment of human hepatic stellate cells via the Kruppel-like factor 2 pathway. Rev Esp Enferm Dig (2015) 1.39
Accelerated development of pressure overload-induced cardiac hypertrophy and dysfunction in an RyR2-R176Q knockin mouse model. Hypertension (2010) 1.39
Phase II study of belinostat in patients with recurrent or refractory advanced thymic epithelial tumors. J Clin Oncol (2011) 1.36
Circulatory miR34a as an RNAbased, noninvasive biomarker for brain aging. Aging (Albany NY) (2011) 1.35
Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver. Am J Physiol Gastrointest Liver Physiol (2008) 1.34
Intergenic and repeat transcription in human, chimpanzee and macaque brains measured by RNA-Seq. PLoS Comput Biol (2010) 1.33
Identification of MyD88 as a novel target of miR-155, involved in negative regulation of Helicobacter pylori-induced inflammation. FEBS Lett (2010) 1.33
Up-regulated microRNA-146a negatively modulate Helicobacter pylori-induced inflammatory response in human gastric epithelial cells. Microbes Infect (2010) 1.33
SOX2 promotes tumor metastasis by stimulating epithelial-to-mesenchymal transition via regulation of WNT/β-catenin signal network. Cancer Lett (2013) 1.32
Detection of antibodies specific to an antigenic cell wall galactomannoprotein for serodiagnosis of Aspergillus fumigatus aspergillosis. J Clin Microbiol (2002) 1.32
Pseudorabies virus variant in Bartha-K61-vaccinated pigs, China, 2012. Emerg Infect Dis (2013) 1.31
An NMR-based model of the ubiquitin-bound human ubiquitin conjugation complex Mms2.Ubc13. The structural basis for lysine 63 chain catalysis. J Biol Chem (2003) 1.30
Oxidized Ca(2+)/calmodulin-dependent protein kinase II triggers atrial fibrillation. Circulation (2013) 1.29
A p53-dominant transcriptional response to cisplatin in testicular germ cell tumor-derived human embryonal carcinoma. Oncogene (2005) 1.28
Subtyping Cryptosporidium ubiquitum,a zoonotic pathogen emerging in humans. Emerg Infect Dis (2014) 1.28
Allogeneic mesenchymal stem cell treatment alleviates experimental and clinical Sjögren syndrome. Blood (2012) 1.27
High recombination rates and hotspots in a Plasmodium falciparum genetic cross. Genome Biol (2011) 1.27
Extension of cortical synaptic development distinguishes humans from chimpanzees and macaques. Genome Res (2012) 1.27
Exosomes as biomarker enriched microvesicles: characterization of exosomal proteins derived from a panel of prostate cell lines with distinct AR phenotypes. Mol Cell Proteomics (2012) 1.26
Surface-immobilized aptamers for cancer cell isolation and microscopic cytology. Cancer Res (2010) 1.26
Site-directed mutagenesis by combination of homologous recombination and DpnI digestion of the plasmid template in Escherichia coli. Anal Biochem (2007) 1.24
MicroRNA regulation in Ames dwarf mouse liver may contribute to delayed aging. Aging Cell (2009) 1.24
Characterization of the complete mitochondrial genome of the giant silkworm moth, Eriogyna pyretorum (Lepidoptera: Saturniidae). Int J Biol Sci (2009) 1.24
Identification of a protein essential for a major pathway used by human cells to avoid UV- induced DNA damage. Proc Natl Acad Sci U S A (2002) 1.23
Delay discounting predicts behavioral sensitization to ethanol in outbred WSC mice. Alcohol Clin Exp Res (2006) 1.23
Widespread splicing changes in human brain development and aging. Mol Syst Biol (2013) 1.23
Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly. Mol Cell Biol (2008) 1.23
Oxygen bridges between NiO nanosheets and graphene for improvement of lithium storage. ACS Nano (2012) 1.23
The yeast Shu complex couples error-free post-replication repair to homologous recombination. Mol Microbiol (2009) 1.22
Studies on a high encapsulation of colchicine by a niosome system. Int J Pharm (2002) 1.22
Mechanisms underlying directional selectivity for frequency-modulated sweeps in the inferior colliculus revealed by in vivo whole-cell recordings. J Neurosci (2009) 1.22
Transcriptional regulation of Fcgr2b gene by polymorphic promoter region and its contribution to humoral immune responses. J Immunol (2002) 1.21
Cryptosporidium genotype and subtype distribution in raw wastewater in Shanghai, China: evidence for possible unique Cryptosporidium hominis transmission. J Clin Microbiol (2008) 1.21
Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis. Oncol Rep (2011) 1.21
ING4 induces G2/M cell cycle arrest and enhances the chemosensitivity to DNA-damage agents in HepG2 cells. FEBS Lett (2004) 1.20
Neuroprotectin D1 synthesis and corneal nerve regeneration after experimental surgery and treatment with PEDF plus DHA. Invest Ophthalmol Vis Sci (2009) 1.20
Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy. Proc Natl Acad Sci U S A (2010) 1.20