Published in ACS Chem Biol on December 17, 2015
The expanding scope and impact of epigenetic cytosine modifications. Curr Opin Chem Biol (2016) 0.77
Role of Base Excision "Repair" Enzymes in Erasing Epigenetic Marks from DNA. Chem Rev (2016) 0.75
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science (2009) 32.97
Instability and decay of the primary structure of DNA. Nature (1993) 25.58
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature (2010) 18.63
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science (2011) 14.29
Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci (2006) 13.32
Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science (2011) 13.16
Active DNA demethylation: many roads lead to Rome. Nat Rev Mol Cell Biol (2010) 9.35
Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites. J Biol Chem (2011) 4.64
The discovery of 5-formylcytosine in embryonic stem cell DNA. Angew Chem Int Ed Engl (2011) 4.39
DNA demethylation dynamics. Cell (2011) 3.82
Genome-wide profiling of 5-formylcytosine reveals its roles in epigenetic priming. Cell (2013) 3.13
Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics. Cell (2013) 3.09
A mechanistic perspective on the chemistry of DNA repair glycosylases. Chem Rev (2003) 2.84
"Aromatic" substituent constants for structure-activity correlations. J Med Chem (1973) 2.54
Specificity of human thymine DNA glycosylase depends on N-glycosidic bond stability. J Am Chem Soc (2006) 2.52
Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat Chem Biol (2012) 2.45
Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells. Proc Natl Acad Sci U S A (1990) 2.42
The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair. DNA Repair (Amst) (2007) 2.26
Tautomeric forms in a polynucleotide helix and their bearing on the structure of DNA. Proc Natl Acad Sci U S A (1961) 2.17
A formula for correlating pKa values determined in D2O and H2O. J Inorg Biochem (2004) 2.07
AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation. Nat Chem Biol (2012) 2.04
Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase. Genome Biol (2012) 1.94
Deconvolutions based on singular value decomposition and the pseudoinverse: a guide for beginners. J Biochem Biophys Methods (1994) 1.87
Syntheses of 5-formyl- and 5-carboxyl-dC containing DNA oligos as potential oxidation products of 5-hydroxymethylcytosine in DNA. Org Lett (2011) 1.82
Excision of 5-halogenated uracils by human thymine DNA glycosylase. Robust activity for DNA contexts other than CpG. J Biol Chem (2007) 1.46
Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation. Nucleic Acids Res (2012) 1.35
Conformation and proton configuration of pyrimidine deoxynucleoside oxidation damage products in water. Chem Res Toxicol (2000) 1.19
Synthesis and properties of oligonucleotides containing 5-formyl-2'-deoxycytidine: in vitro DNA polymerase reactions on DNA templates containing 5-formyl-2'-deoxycytidine. Nucleic Acids Res (2001) 1.13
Two-dimensional Fourier transform spectroscopy in the pump-probe geometry. Opt Lett (2007) 1.01
Anharmonic vibrational modes of nucleic acid bases revealed by 2D IR spectroscopy. J Am Chem Soc (2011) 0.97
Divergent mechanisms for enzymatic excision of 5-formylcytosine and 5-carboxylcytosine from DNA. J Am Chem Soc (2013) 0.93
Direct observation of ground-state lactam-lactim tautomerization using temperature-jump transient 2D IR spectroscopy. Proc Natl Acad Sci U S A (2013) 0.90
Synthesis and properties of oligodeoxynucleotides containing 5-carboxy-2'-deoxycytidines. Bioorg Med Chem Lett (2007) 0.89
Identification of Lactam-Lactim Tautomers of Aromatic Heterocycles in Aqueous Solution Using 2D IR Spectroscopy. J Phys Chem Lett (2012) 0.88
Pure component spectral reconstruction from mixture data using SVD, global entropy minimization, and simulated annealing. Numerical investigations of admissible objective functions using a synthetic 7-species data set. J Comput Chem (2002) 0.77
Two-dimensional IR spectroscopy of the anti-HIV agent KP1212 reveals protonated and neutral tautomers that influence pH-dependent mutagenicity. Proc Natl Acad Sci U S A (2015) 0.77