Published in DNA Repair (Amst) on January 08, 2007
Base-excision repair of oxidative DNA damage. Nature (2007) 5.44
Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells. Cell Res (2008) 3.48
Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA. Nat Chem Biol (2012) 2.45
A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification. DNA Repair (Amst) (2007) 2.43
Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks. DNA Repair (Amst) (2010) 1.96
Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair. J Nucleic Acids (2010) 1.91
Flipping of alkylated DNA damage bridges base and nucleotide excision repair. Nature (2009) 1.70
Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source. J Appl Crystallogr (2013) 1.69
The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo. Proc Natl Acad Sci U S A (2010) 1.61
The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions. Nature (2015) 1.48
XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase. DNA Repair (Amst) (2011) 1.45
Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes. Proc Natl Acad Sci U S A (2009) 1.36
Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase. Nature (2010) 1.36
DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy. DNA Repair (Amst) (2007) 1.36
DNA damage and autophagy. Mutat Res (2011) 1.34
Single Qdot-labeled glycosylase molecules use a wedge amino acid to probe for lesions while scanning along DNA. Nucleic Acids Res (2011) 1.32
Structural dynamics in DNA damage signaling and repair. Curr Opin Struct Biol (2010) 1.31
Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair. Nat Struct Mol Biol (2009) 1.26
Reduced local mutation density in regulatory DNA of cancer genomes is linked to DNA repair. Nat Biotechnol (2013) 1.21
Three metal ions participate in the reaction catalyzed by T5 flap endonuclease. J Biol Chem (2008) 1.16
XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair. Biochem Cell Biol (2013) 1.09
Hierarchy of lesion processing governs the repair, double-strand break formation and mutability of three-lesion clustered DNA damage. Nucleic Acids Res (2009) 1.09
Atomic substitution reveals the structural basis for substrate adenine recognition and removal by adenine DNA glycosylase. Proc Natl Acad Sci U S A (2009) 1.08
Base excision repair: a critical player in many games. DNA Repair (Amst) (2014) 1.08
Flap endonucleases pass 5'-flaps through a flexible arch using a disorder-thread-order mechanism to confer specificity for free 5'-ends. Nucleic Acids Res (2012) 1.06
Biochemical and structural characterization of the glycosylase domain of MBD4 bound to thymine and 5-hydroxymethyuracil-containing DNA. Nucleic Acids Res (2012) 1.06
The cutting edges in DNA repair, licensing, and fidelity: DNA and RNA repair nucleases sculpt DNA to measure twice, cut once. DNA Repair (Amst) (2014) 1.04
Entrapment and structure of an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase, MutM. J Biol Chem (2009) 1.03
Unpairing and gating: sequence-independent substrate recognition by FEN superfamily nucleases. Trends Biochem Sci (2011) 1.02
Non-specific DNA binding interferes with the efficient excision of oxidative lesions from chromatin by the human DNA glycosylase, NEIL1. DNA Repair (Amst) (2009) 1.01
The human oxidative DNA glycosylase NEIL1 excises psoralen-induced interstrand DNA cross-links in a three-stranded DNA structure. J Biol Chem (2009) 1.01
Thermodynamics of the multi-stage DNA lesion recognition and repair by formamidopyrimidine-DNA glycosylase using pyrrolocytosine fluorescence--stopped-flow pre-steady-state kinetics. Nucleic Acids Res (2012) 1.01
Adenine removal activity and bacterial complementation with the human MutY homologue (MUTYH) and Y165C, G382D, P391L and Q324R variants associated with colorectal cancer. DNA Repair (Amst) (2009) 1.00
Formation and repair of tobacco carcinogen-derived bulky DNA adducts. J Nucleic Acids (2010) 0.98
Base excision repair, aging and health span. Mech Ageing Dev (2008) 0.97
Emerging critical roles of Fe-S clusters in DNA replication and repair. Biochim Biophys Acta (2015) 0.96
Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes. J Biol Chem (2013) 0.96
Crystal structure of human methyl-binding domain IV glycosylase bound to abasic DNA. J Mol Biol (2012) 0.93
The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions. J Mol Biol (2013) 0.93
Alkyltransferase-like proteins: molecular switches between DNA repair pathways. Cell Mol Life Sci (2010) 0.92
Combining H/D exchange mass spectroscopy and computational docking reveals extended DNA-binding surface on uracil-DNA glycosylase. Nucleic Acids Res (2012) 0.90
Unusual structural features of hydantoin lesions translate into efficient recognition by Escherichia coli Fpg. Biochemistry (2007) 0.90
Double strand binding-single strand incision mechanism for human flap endonuclease: implications for the superfamily. Mech Ageing Dev (2012) 0.90
Genetic analysis of repair and damage tolerance mechanisms for DNA-protein cross-links in Escherichia coli. J Bacteriol (2009) 0.89
Selective excision of 5-carboxylcytosine by a thymine DNA glycosylase mutant. J Mol Biol (2013) 0.89
Alkyltransferase-like protein (Atl1) distinguishes alkylated guanines for DNA repair using cation-π interactions. Proc Natl Acad Sci U S A (2012) 0.89
Mechanisms for enzymatic cleavage of the N-glycosidic bond in DNA. Org Biomol Chem (2014) 0.88
Myelodysplastic syndrome: an inability to appropriately respond to damaged DNA? Exp Hematol (2013) 0.87
Regulation of DNA glycosylases and their role in limiting disease. Free Radic Res (2012) 0.87
Genetic and biochemical characterization of human AP endonuclease 1 mutants deficient in nucleotide incision repair activity. PLoS One (2010) 0.86
Repair of O4-alkylthymine by O6-alkylguanine-DNA alkyltransferases. J Biol Chem (2009) 0.86
Substrate specificity and sequence-dependent activity of the Saccharomyces cerevisiae 3-methyladenine DNA glycosylase (Mag). DNA Repair (Amst) (2008) 0.85
Age-related instability in spermatogenic cell nuclear and mitochondrial DNA obtained from Apex1 heterozygous mice. Mol Reprod Dev (2011) 0.85
Activity and crystal structure of human thymine DNA glycosylase mutant N140A with 5-carboxylcytosine DNA at low pH. DNA Repair (Amst) (2013) 0.84
New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways. PLoS One (2011) 0.84
A haplotype variation affecting the mitochondrial transportation of hMYH protein could be a risk factor for colorectal cancer in Chinese. BMC Cancer (2008) 0.84
Wedging out DNA damage. Nat Struct Mol Biol (2009) 0.84
DNA-binding properties of T4 UvsY recombination mediator protein: polynucleotide wrapping promotes high-affinity binding to single-stranded DNA. Nucleic Acids Res (2010) 0.83
Trapping and structural elucidation of a very advanced intermediate in the lesion-extrusion pathway of hOGG1. J Am Chem Soc (2008) 0.83
Functional complementation of UvsX and UvsY mutations in the mediation of T4 homologous recombination. Nucleic Acids Res (2009) 0.80
Sculpting of DNA at abasic sites by DNA glycosylase homolog mag2. Structure (2012) 0.80
The role of MutY homolog (Myh1) in controlling the histone deacetylase Hst4 in the fission yeast Schizosaccharomyces pombe. J Mol Biol (2010) 0.80
Eukaryotic class II cyclobutane pyrimidine dimer photolyase structure reveals basis for improved ultraviolet tolerance in plants. J Biol Chem (2011) 0.80
Light-induced conformational change and product release in DNA repair by (6-4) photolyase. J Am Chem Soc (2011) 0.80
ALKBH1 is dispensable for abasic site cleavage during base excision repair and class switch recombination. PLoS One (2013) 0.80
Cloning and characterization of a wheat homologue of apurinic/apyrimidinic endonuclease Ape1L. PLoS One (2014) 0.79
A mutation in the FHA domain of Coprinus cinereus Nbs1 Leads to Spo11-independent meiotic recombination and chromosome segregation. G3 (Bethesda) (2013) 0.79
A TetR family transcriptional factor directly regulates the expression of a 3-methyladenine DNA glycosylase and physically interacts with the enzyme to stimulate its base excision activity in Mycobacterium bovis BCG. J Biol Chem (2014) 0.78
Highly mutagenic exocyclic DNA adducts are substrates for the human nucleotide incision repair pathway. PLoS One (2012) 0.78
Targeting DNA polymerase ß for therapeutic intervention. Curr Mol Pharmacol (2012) 0.78
Crystallization and preliminary X-ray analysis of human endonuclease 1 (APE1) in complex with an oligonucleotide containing a 5,6-dihydrouracil (DHU) or an alpha-anomeric 2'-deoxyadenosine (alphadA) modified base. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.77
Base excision repair and the role of MUTYH. Hered Cancer Clin Pract (2007) 0.77
A dynamic checkpoint in oxidative lesion discrimination by formamidopyrimidine-DNA glycosylase. Nucleic Acids Res (2015) 0.77
Interaction of apurinic/apyrimidinic endonuclease 2 (Apn2) with Myh1 DNA glycosylase in fission yeast. DNA Repair (Amst) (2014) 0.77
Archaeal genome guardians give insights into eukaryotic DNA replication and damage response proteins. Archaea (2014) 0.77
Weakened N3 Hydrogen Bonding by 5-Formylcytosine and 5-Carboxylcytosine Reduces Their Base-Pairing Stability. ACS Chem Biol (2015) 0.77
Aberrant repair initiated by mismatch-specific thymine-DNA glycosylases provides a mechanism for the mutational bias observed in CpG islands. Nucleic Acids Res (2014) 0.77
Templated chemistry for monitoring damage and repair directly in duplex DNA. Chem Commun (Camb) (2012) 0.77
Mechanism of translocation of uracil-DNA glycosylase from Escherichia coli between distributed lesions. Biochem Biophys Res Commun (2011) 0.77
Structure of the endonuclease IV homologue from Thermotoga maritima in the presence of active-site divalent metal ions. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.77
Potential relationship between inadequate response to DNA damage and development of myelodysplastic syndrome. Int J Mol Sci (2015) 0.76
Crystal structure of E. coli endonuclease V, an essential enzyme for deamination repair. Sci Rep (2015) 0.76
Poly(ADP-ribose) polymerases covalently modify strand break termini in DNA fragments in vitro. Nucleic Acids Res (2016) 0.76
Early Steps in the DNA Base Excision Repair Pathway of a Fission Yeast Schizosaccharomyces pombe. J Nucleic Acids (2010) 0.76
Alkylpurine glycosylase D employs DNA sculpting as a strategy to extrude and excise damaged bases. PLoS Comput Biol (2014) 0.75
Dynamic structures in DNA damage responses & cancer. Prog Biophys Mol Biol (2015) 0.75
Finding needles in DNA stacks. Proc Natl Acad Sci U S A (2009) 0.75
Toxicity and repair of DNA adducts produced by the natural product yatakemycin. Nat Chem Biol (2017) 0.75
Association of monoallelic MUTYH mutation among Egyptian patients with colorectal cancer. Fam Cancer (2017) 0.75
X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution. Q Rev Biophys (2007) 9.07
Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS). Nat Methods (2009) 6.77
Type IV pilus structure and bacterial pathogenicity. Nat Rev Microbiol (2004) 4.29
Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair. Cell (2008) 4.26
UV-induced ubiquitylation of XPC protein mediated by UV-DDB-ubiquitin ligase complex. Cell (2005) 3.85
The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair. Nature (2002) 3.48
Type IV pilus structure by cryo-electron microscopy and crystallography: implications for pilus assembly and functions. Mol Cell (2006) 3.36
Structural basis for FEN-1 substrate specificity and PCNA-mediated activation in DNA replication and repair. Cell (2004) 3.33
Accurate assessment of mass, models and resolution by small-angle scattering. Nature (2013) 3.18
XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutations. Cell (2008) 3.14
Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template. Biochem Cell Biol (2007) 3.13
Full-length archaeal Rad51 structure and mutants: mechanisms for RAD51 assembly and control by BRCA2. EMBO J (2003) 2.95
Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair. Cell (2009) 2.90
Characterizing flexible and intrinsically unstructured biological macromolecules by SAS using the Porod-Debye law. Biopolymers (2011) 2.87
DNA binding and nucleotide flipping by the human DNA repair protein AGT. Nat Struct Mol Biol (2004) 2.86
Type IV pilin structure and assembly: X-ray and EM analyses of Vibrio cholerae toxin-coregulated pilus and Pseudomonas aeruginosa PAK pilin. Mol Cell (2003) 2.78
SUMO-targeted ubiquitin ligases in genome stability. EMBO J (2007) 2.77
Microbial metalloproteomes are largely uncharacterized. Nature (2010) 2.62
Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex. Cell (2008) 2.47
Bridging the solution divide: comprehensive structural analyses of dynamic RNA, DNA, and protein assemblies by small-angle X-ray scattering. Curr Opin Struct Biol (2010) 2.45
Human flap endonuclease structures, DNA double-base flipping, and a unified understanding of the FEN1 superfamily. Cell (2011) 2.44
Preferential cis-syn thymine dimer bypass by DNA polymerase eta occurs with biased fidelity. Nature (2004) 2.40
ATM regulates Mre11-dependent DNA end-degradation and microhomology-mediated end joining. Cell Cycle (2010) 2.32
Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase. J Biol Chem (2004) 2.28
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage. EMBO J (2006) 2.27
A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNA. Mol Cell (2006) 2.23
DNA base damage recognition and removal: new twists and grooves. Mutat Res (2005) 2.21
The molecular basis of CRL4DDB2/CSA ubiquitin ligase architecture, targeting, and activation. Cell (2011) 2.16
The DNA repair endonuclease XPG interacts directly and functionally with the WRN helicase defective in Werner syndrome. Cell Cycle (2011) 2.15
Conserved XPB core structure and motifs for DNA unwinding: implications for pathway selection of transcription or excision repair. Mol Cell (2006) 2.13
Identification of a new cryptochrome class. Structure, function, and evolution. Mol Cell (2003) 2.11
High-efficiency bypass of DNA damage by human DNA polymerase Q. EMBO J (2004) 2.07
A SIM-ultaneous role for SUMO and ubiquitin. Trends Biochem Sci (2008) 2.05
Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks. DNA Repair (Amst) (2010) 1.96
Rad50/SMC proteins and ABC transporters: unifying concepts from high-resolution structures. Curr Opin Struct Biol (2003) 1.93
Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex. J Biol Chem (2009) 1.91
MDB: the Metalloprotein Database and Browser at The Scripps Research Institute. Nucleic Acids Res (2002) 1.89
Recognition of RNA polymerase II and transcription bubbles by XPG, CSB, and TFIIH: insights for transcription-coupled repair and Cockayne Syndrome. Mol Cell (2005) 1.89
Palm mutants in DNA polymerases alpha and eta alter DNA replication fidelity and translesion activity. Mol Cell Biol (2004) 1.85
Accurate SAXS profile computation and its assessment by contrast variation experiments. Biophys J (2013) 1.83
ALS mutants of human superoxide dismutase form fibrous aggregates via framework destabilization. J Mol Biol (2003) 1.82
Hexameric structures of the archaeal secretion ATPase GspE and implications for a universal secretion mechanism. EMBO J (2007) 1.77
DNA charge transport as a first step in coordinating the detection of lesions by repair proteins. Proc Natl Acad Sci U S A (2012) 1.71
A structural model for regulation of NHEJ by DNA-PKcs autophosphorylation. DNA Repair (Amst) (2010) 1.71
Translesion synthesis by human DNA polymerase eta across thymine glycol lesions. Biochemistry (2002) 1.71
Flipping of alkylated DNA damage bridges base and nucleotide excision repair. Nature (2009) 1.70
Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source. J Appl Crystallogr (2013) 1.69
DNA double-strand break repair from head to tail. Curr Opin Struct Biol (2002) 1.67
ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair. Nat Struct Mol Biol (2011) 1.66
Nickel superoxide dismutase structure and mechanism. Biochemistry (2004) 1.66
Improving small-angle X-ray scattering data for structural analyses of the RNA world. RNA (2010) 1.60
Crystal structure of the DNA repair enzyme ultraviolet damage endonuclease. Structure (2007) 1.59
Centrin 2 stimulates nucleotide excision repair by interacting with xeroderma pigmentosum group C protein. Mol Cell Biol (2005) 1.58
WRN exonuclease structure and molecular mechanism imply an editing role in DNA end processing. Nat Struct Mol Biol (2006) 1.55
Differential specificity of human and Escherichia coli endonuclease III and VIII homologues for oxidative base lesions. J Biol Chem (2004) 1.53
A molecular mechanism for DNA damage recognition by the xeroderma pigmentosum group C protein complex. DNA Repair (Amst) (2002) 1.53
Human DNA polymerase N (POLN) is a low fidelity enzyme capable of error-free bypass of 5S-thymine glycol. J Biol Chem (2006) 1.49
XRCC4 protein interactions with XRCC4-like factor (XLF) create an extended grooved scaffold for DNA ligation and double strand break repair. J Biol Chem (2011) 1.48
Fate of DNA replication fork encountering a single DNA lesion during oriC plasmid DNA replication in vitro. Genes Cells (2003) 1.48
Protein mimicry of DNA and pathway regulation. DNA Repair (Amst) (2005) 1.46
DNA apurinic-apyrimidinic site binding and excision by endonuclease IV. Nat Struct Mol Biol (2008) 1.46
XPB and XPD helicases in TFIIH orchestrate DNA duplex opening and damage verification to coordinate repair with transcription and cell cycle via CAK kinase. DNA Repair (Amst) (2011) 1.45
Mechanism and energetics of green fluorescent protein chromophore synthesis revealed by trapped intermediate structures. Proc Natl Acad Sci U S A (2003) 1.41
Report of the wwPDB Small-Angle Scattering Task Force: data requirements for biomolecular modeling and the PDB. Structure (2013) 1.39
DDB1-DDB2 (xeroderma pigmentosum group E) protein complex recognizes a cyclobutane pyrimidine dimer, mismatches, apurinic/apyrimidinic sites, and compound lesions in DNA. J Biol Chem (2005) 1.38
Proliferating cell nuclear antigen loaded onto double-stranded DNA: dynamics, minor groove interactions and functional implications. Nucleic Acids Res (2006) 1.37
Structural basis for endothelial nitric oxide synthase binding to calmodulin. EMBO J (2003) 1.37
Two-step recognition of DNA damage for mammalian nucleotide excision repair: Directional binding of the XPC complex and DNA strand scanning. Mol Cell (2009) 1.37
Functional motifs in the (6-4) photolyase crystal structure make a comparative framework for DNA repair photolyases and clock cryptochromes. Proc Natl Acad Sci U S A (2009) 1.36
Super-resolution in solution X-ray scattering and its applications to structural systems biology. Annu Rev Biophys (2013) 1.36
Identification of cryptochrome DASH from vertebrates. Genes Cells (2004) 1.36
DNA binding, nucleotide flipping, and the helix-turn-helix motif in base repair by O6-alkylguanine-DNA alkyltransferase and its implications for cancer chemotherapy. DNA Repair (Amst) (2007) 1.36
Generic expansion of the substrate spectrum of a DNA polymerase by directed evolution. Nat Biotechnol (2004) 1.34
XLF regulates filament architecture of the XRCC4·ligase IV complex. Structure (2010) 1.33
Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis. J Mol Biol (2008) 1.32
Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states. Biochemistry (2010) 1.32
Structural dynamics in DNA damage signaling and repair. Curr Opin Struct Biol (2010) 1.31
Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radiodurans. Proc Natl Acad Sci U S A (2001) 1.30
An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress. J Biol Chem (2003) 1.30
Comprehensive macromolecular conformations mapped by quantitative SAXS analyses. Nat Methods (2013) 1.29
gammaH2A binds Brc1 to maintain genome integrity during S-phase. EMBO J (2010) 1.28
The XPC-HR23B complex displays high affinity and specificity for damaged DNA in a true-equilibrium fluorescence assay. Biochemistry (2002) 1.26
Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS. J Mol Biol (2007) 1.26
Structures of endonuclease V with DNA reveal initiation of deaminated adenine repair. Nat Struct Mol Biol (2009) 1.26
Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase. Nat Chem Biol (2008) 1.25
A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase. J Mol Biol (2006) 1.25
High-throughput SAXS for the characterization of biomolecules in solution: a practical approach. Methods Mol Biol (2014) 1.22
The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase. Nucleic Acids Res (2007) 1.21
Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography. J Struct Biol (2006) 1.21
Insights into Lou Gehrig's disease from the structure and instability of the A4V mutant of human Cu,Zn superoxide dismutase. J Mol Biol (2002) 1.20
Structural tuning of the fluorescent protein iLOV for improved photostability. J Biol Chem (2012) 1.19
The rad50 signature motif: essential to ATP binding and biological function. J Mol Biol (2004) 1.19
Three metal ions participate in the reaction catalyzed by T5 flap endonuclease. J Biol Chem (2008) 1.16
Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element. Nat Struct Mol Biol (2012) 1.16
The structure of the CRISPR-associated protein Csa3 provides insight into the regulation of the CRISPR/Cas system. J Mol Biol (2010) 1.16
REV1 restrains DNA polymerase zeta to ensure frame fidelity during translesion synthesis of UV photoproducts in vivo. Nucleic Acids Res (2008) 1.15
Molecular mimicry of SUMO promotes DNA repair. Nat Struct Mol Biol (2009) 1.14
Unraveling the three-metal-ion catalytic mechanism of the DNA repair enzyme endonuclease IV. Proc Natl Acad Sci U S A (2007) 1.14