Published in Redox Biol on November 29, 2015
Complement Regulator FHR-3 Is Elevated either Locally or Systemically in a Selection of Autoimmune Diseases. Front Immunol (2016) 0.75
miR-17-3p Exacerbates Oxidative Damage in Human Retinal Pigment Epithelial Cells. PLoS One (2016) 0.75
Effects of Benzo(e)pyrene on Reactive Oxygen/Nitrogen Species and Inflammatory Cytokines Induction in Human RPE Cells and Attenuation by Mitochondrial-involved Mechanism. J Ophthalmic Vis Res (2016) 0.75
Nutritional Supplementation Inhibits the Increase in Serum Malondialdehyde in Patients with Wet Age-Related Macular Degeneration. Oxid Med Cell Longev (2017) 0.75
Human umbilical cord-derived mesenchymal stromal cells protect against premature renal senescence resulting from oxidative stress in rats with acute kidney injury. Stem Cell Res Ther (2017) 0.75
Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model. Oxid Med Cell Longev (2017) 0.75
Epithelial cell senescence: an adaptive response to pre-carcinogenic stresses? Cell Mol Life Sci (2017) 0.75
Complement factor H polymorphism and age-related macular degeneration. Science (2005) 17.79
Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol (2007) 16.55
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders. Nature (2011) 8.45
The essence of senescence. Genes Dev (2010) 8.21
The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol (2000) 8.10
The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol (2010) 7.58
Four faces of cellular senescence. J Cell Biol (2011) 6.86
Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo. Nat Protoc (2009) 4.47
Age-related macular degeneration. Lancet (2012) 4.17
Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis. Lancet Glob Health (2014) 3.95
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities. J Clin Invest (2013) 3.47
The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited. Prog Retin Eye Res (2009) 3.40
Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence. J Biol Chem (2006) 3.00
Oxidative damage and age-related macular degeneration. Mol Vis (1999) 2.97
Smoking and age-related macular degeneration: a review of association. Eye (Lond) (2005) 2.77
Smoking and age related macular degeneration: the number of pack years of cigarette smoking is a major determinant of risk for both geographic atrophy and choroidal neovascularisation. Br J Ophthalmol (2006) 2.67
Oxidative damage and protection of the RPE. Prog Retin Eye Res (2000) 2.65
Clinical risk factors for age-related macular degeneration: a systematic review and meta-analysis. BMC Ophthalmol (2010) 2.32
Phototransduction, dark adaptation, and rhodopsin regeneration the proctor lecture. Invest Ophthalmol Vis Sci (2006) 2.17
Immunology of age-related macular degeneration. Nat Rev Immunol (2013) 2.14
Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype. J Biol Chem (2011) 2.11
Progression of age-related macular degeneration: prospective assessment of C-reactive protein, interleukin 6, and other cardiovascular biomarkers. Arch Ophthalmol (2005) 2.08
The estimated prevalence and incidence of late stage age related macular degeneration in the UK. Br J Ophthalmol (2012) 2.02
Interleukin-8 promoter polymorphism -251A/T is a risk factor for age-related macular degeneration. Br J Ophthalmol (2008) 1.97
Oxidatively generated base damage to cellular DNA. Free Radic Biol Med (2010) 1.82
Anti-vascular endothelial growth factor for neovascular age-related macular degeneration. Cochrane Database Syst Rev (2014) 1.76
Smoking and the 5-year incidence of age-related maculopathy: the Blue Mountains Eye Study. Arch Ophthalmol (2002) 1.71
Beta-galactosidase histochemistry and telomere loss in senescent retinal pigment epithelial cells. Invest Ophthalmol Vis Sci (1999) 1.67
Vascular endothelial growth factor a in intraocular vascular disease. Ophthalmology (2012) 1.63
Consequences of oxidative stress in age-related macular degeneration. Mol Aspects Med (2012) 1.59
Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence. Epigenetics Chromatin (2008) 1.50
Common micro RNAs (miRNAs) target complement factor H (CFH) regulation in Alzheimer's disease (AD) and in age-related macular degeneration (AMD). Int J Biochem Mol Biol (2012) 1.37
Synthesis of complement factor H by retinal pigment epithelial cells is down-regulated by oxidized photoreceptor outer segments. Exp Eye Res (2006) 1.36
Senescence-associated beta-galactosidase histochemistry for the primate eye. Invest Ophthalmol Vis Sci (1999) 1.32
The role of aging, high fat diet and blue light exposure in an experimental mouse model for basal laminar deposit formation. Exp Eye Res (2002) 1.28
Cigarette smoking, oxidative stress, the anti-oxidant response through Nrf2 signaling, and Age-related Macular Degeneration. Vision Res (2009) 1.28
Quantitative autofluorescence and cell density maps of the human retinal pigment epithelium. Invest Ophthalmol Vis Sci (2014) 1.27
Senescent cells: a novel therapeutic target for aging and age-related diseases. Clin Pharmacol Ther (2012) 1.25
Ascorbate is depleted by smoking and repleted by moderate supplementation: a study in male smokers and nonsmokers with matched dietary antioxidant intakes. Am J Clin Nutr (2000) 1.22
The thorny path linking cellular senescence to organismal aging. Mech Ageing Dev (2005) 1.22
Chronic photo-oxidative stress and subsequent MCP-1 activation as causative factors for age-related macular degeneration. J Cell Sci (2012) 1.15
Concentration of cytokines in the aqueous humor of patients with naive, recurrent and regressed CNV associated with amd after bevacizumab treatment. Retina (2009) 1.14
Cell senescence: role in aging and age-related diseases. Interdiscip Top Gerontol (2014) 1.14
MicroRNA changes in human arterial endothelial cells with senescence: relation to apoptosis, eNOS and inflammation. Exp Gerontol (2011) 1.13
Acridine Orange/Ethidium Bromide (AO/EB) Staining to Detect Apoptosis. CSH Protoc (2006) 1.10
C-reactive protein and complement factor H in aged human eyes and eyes with age-related macular degeneration. Br J Ophthalmol (2011) 1.09
BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration. J Biol Chem (2009) 1.07
Lipofuscin redistribution and loss accompanied by cytoskeletal stress in retinal pigment epithelium of eyes with age-related macular degeneration. Invest Ophthalmol Vis Sci (2015) 1.06
Cytokine concentration in aqueous humour of eyes with exudative age-related macular degeneration. Acta Ophthalmol (2012) 1.05
Repetitive nonlethal oxidant injury to retinal pigment epithelium decreased extracellular matrix turnover in vitro and induced sub-RPE deposits in vivo. Invest Ophthalmol Vis Sci (2006) 1.04
Senescent cells: SASPected drivers of age-related pathologies. Biogerontology (2014) 1.03
Inflammatory cytokines in aqueous humor of patients with choroidal neovascularization. Mol Vis (2012) 1.02
Interleukin gene polymorphisms in age-related macular degeneration. Invest Ophthalmol Vis Sci (2008) 1.02
Bacterial endotoxin activates retinal pigment epithelial cells and induces their degeneration through IL-6 and IL-8 autocrine signaling. Mol Immunol (2009) 1.02
RPE cell senescence: a key contributor to age-related macular degeneration. Med Hypotheses (2012) 1.01
Seeing through VEGF: innate and adaptive immunity in pathological angiogenesis in the eye. Trends Mol Med (2014) 1.00
Senescent cells and their secretory phenotype as targets for cancer therapy. Interdiscip Top Gerontol (2013) 1.00
Recovery of function in osteoarthritic chondrocytes induced by p16INK4a-specific siRNA in vitro. Rheumatology (Oxford) (2004) 0.99
Progressive dysfunction of the retinal pigment epithelium and retina due to increased VEGF-A levels. FASEB J (2014) 0.98
Subtoxic oxidative stress induces senescence in retinal pigment epithelial cells via TGF-beta release. Invest Ophthalmol Vis Sci (2009) 0.97
MitomiRs in human inflamm-aging: a hypothesis involving miR-181a, miR-34a and miR-146a. Exp Gerontol (2014) 0.97
Role of ocular complement factor H in a murine model of choroidal neovascularization. Am J Pathol (2010) 0.95
Redox theory of aging. Redox Biol (2015) 0.95
DNA damage as a molecular link in the pathogenesis of COPD in smokers. Eur Respir J (2012) 0.92
Associations of cigarette smoking but not serum fatty acids with age-related macular degeneration in a Japanese population. Ophthalmology (2011) 0.91
Mechanisms of ocular angiogenesis and its molecular mediators. Dev Ophthalmol (2010) 0.90
Light-induced retinal damage in mice. Hydrogen peroxide production and superoxide dismutase activity in retina. Retina (1992) 0.89
Risk factors for four-year incidence and progression of age-related macular degeneration: the los angeles latino eye study. Am J Ophthalmol (2011) 0.88
Biological effects of cigarette smoke in cultured human retinal pigment epithelial cells. PLoS One (2012) 0.88
DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging. Oncotarget (2015) 0.87
Cell senescence in human aging and disease. Ann N Y Acad Sci (2002) 0.87
A comparison of the free radical chemistry of tobacco-burning cigarettes and cigarettes that only heat tobacco. Free Radic Biol Med (1990) 0.86
Smoking history and the incidence of age-related macular degeneration--results from the Muenster Aging and Retina Study (MARS) cohort and systematic review and meta-analysis of observational longitudinal studies. Addict Behav (2009) 0.86
Aβ-induced senescent retinal pigment epithelial cells create a proinflammatory microenvironment in AMD. Invest Ophthalmol Vis Sci (2013) 0.85
Cellular senescence and the aging brain. Exp Gerontol (2014) 0.85
Prematurely senescent ARPE-19 cells display features of age-related macular degeneration. Free Radic Biol Med (2008) 0.83
Senescence-Induced Oxidative Stress Causes Endothelial Dysfunction. J Gerontol A Biol Sci Med Sci (2015) 0.81
Perturbation of cellular immune functions in cigarette smokers and protection by palm oil vitamin E supplementation. Nutr J (2013) 0.81
Subretinal injection of amyloid-β peptide accelerates RPE cell senescence and retinal degeneration. Int J Mol Med (2014) 0.80
Photo-damage, photo-protection and age-related macular degeneration. Photochem Photobiol Sci (2015) 0.79
Age-related macular degeneration: beyond anti-angiogenesis. Mol Vis (2014) 0.79
Senescence associated beta galactosidase activity in human retinal pigment epithelial cells exposed to mild hyperoxia in vitro. Br J Ophthalmol (2002) 0.79
Relationship between the complement system, risk factors and prediction models in age-related macular degeneration. Mol Immunol (2014) 0.79
MicroRNAs and lncRNAs in senescence: A re-view. IUBMB Life (2015) 0.79
Noncoding RNA control of cellular senescence. Wiley Interdiscip Rev RNA (2015) 0.79
Assessment of oxidative stress-induced DNA damage by immunoflourescent analysis of 8-oxodG. Methods Cell Biol (2011) 0.78
A mechanistic review of cigarette smoke and age-related macular degeneration. Adv Exp Med Biol (2014) 0.78
Proteomic analysis reveals novel common genes modulated in both replicative and stress-induced senescence. J Proteomics (2015) 0.78
Methods of cellular senescence induction using oxidative stress. Methods Mol Biol (2013) 0.77
Association of Smoking and CFH and ARMS2 Risk Variants With Younger Age at Onset of Neovascular Age-Related Macular Degeneration. JAMA Ophthalmol (2015) 0.77
Impact of ER stress-regulated ATF4/p16 signaling on the premature senescence of renal tubular epithelial cells in diabetic nephropathy. Am J Physiol Cell Physiol (2015) 0.77
CBX7 and miR-9 are part of an autoregulatory loop controlling p16(INK) (4a). Aging Cell (2015) 0.77
The InflammTORy Powers of Senescence. Trends Cell Biol (2015) 0.76