Published in Mol Cells on December 21, 2015
Direct Reprogramming of Human Dermal Fibroblasts Into Endothelial Cells Using ER71/ETV2. Circ Res (2016) 0.83
The Hemogenic Competence of Endothelial Progenitors Is Restricted by Runx1 Silencing during Embryonic Development. Cell Rep (2016) 0.76
ETV-2 activated proliferation of endothelial cells and attenuated acute hindlimb ischemia in mice. In Vitro Cell Dev Biol Anim (2017) 0.75
The Protein Data Bank. Nucleic Acids Res (2000) 187.10
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell (2006) 120.51
Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell (2007) 101.42
Heart disease and stroke statistics--2015 update: a report from the American Heart Association. Circulation (2014) 22.74
Direct conversion of fibroblasts to functional neurons by defined factors. Nature (2010) 18.76
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell (2010) 15.58
Molecular mechanisms and clinical applications of angiogenesis. Nature (2011) 13.36
Molecular regulation of vessel maturation. Nat Med (2003) 11.74
The myoD gene family: nodal point during specification of the muscle cell lineage. Science (1991) 9.53
An early haematopoietic defect in mice lacking the transcription factor GATA-2. Nature (1994) 8.60
Stepwise reprogramming of B cells into macrophages. Cell (2004) 7.68
Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD. Proc Natl Acad Sci U S A (1989) 7.19
Flk1-positive cells derived from embryonic stem cells serve as vascular progenitors. Nature (2000) 7.15
Induction of human neuronal cells by defined transcription factors. Nature (2011) 6.84
Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature (2012) 6.65
The ETS-domain transcription factor family. Nat Rev Mol Cell Biol (2001) 6.01
Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors. Nature (2011) 5.84
Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5. Genes Dev (1995) 5.53
Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors. Nature (2011) 5.28
Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development (1999) 4.93
Haematopoietic stem cells derive directly from aortic endothelium during development. Nature (2010) 4.42
Fate tracing reveals the endothelial origin of hematopoietic stem cells. Cell Stem Cell (2008) 4.17
In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium. Nature (2010) 4.16
Blood stem cells emerge from aortic endothelium by a novel type of cell transition. Nature (2010) 4.14
Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature. Science (2008) 3.86
The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Development (1999) 3.74
Mesp1 acts as a master regulator of multipotent cardiovascular progenitor specification. Cell Stem Cell (2008) 3.07
Cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages. Development (1995) 3.05
Vasculogenesis in the day 6.5 to 9.5 mouse embryo. Blood (2000) 2.98
Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activity. Genes Dev (2008) 2.91
Genomic and biochemical insights into the specificity of ETS transcription factors. Annu Rev Biochem (2011) 2.89
Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors. Blood (2005) 2.76
Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor. Mol Cell Biol (2000) 2.69
The Ets-1 transcription factor is required for the development of natural killer cells in mice. Immunity (1998) 2.68
Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors. Cell (2008) 2.60
Fli-1 is required for murine vascular and megakaryocytic development and is hemizygously deleted in patients with thrombocytopenia. Immunity (2000) 2.59
Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors. Nucleic Acids Res (2004) 2.55
Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine. Stem Cells (2009) 2.48
Mesp1 coordinately regulates cardiovascular fate restriction and epithelial-mesenchymal transition in differentiating ESCs. Cell Stem Cell (2008) 2.46
ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell (2008) 2.46
Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins. Genes Dev (1992) 2.42
Ets1-related protein is a key regulator of vasculogenesis in zebrafish. PLoS Biol (2006) 2.35
Retinal cell fate determination and bHLH factors. Semin Cell Dev Biol (2004) 2.33
Molecular mechanisms of vasculogenesis and embryonic angiogenesis. J Cell Physiol (1997) 2.27
Combinatorial function of ETS transcription factors in the developing vasculature. Dev Biol (2006) 2.22
Ets1 and Ets2 are required for endothelial cell survival during embryonic angiogenesis. Blood (2009) 2.17
A new pattern for helix-turn-helix recognition revealed by the PU.1 ETS-domain-DNA complex. Nature (1996) 2.17
Vessel and blood specification override cardiac potential in anterior mesoderm. Dev Cell (2007) 2.16
The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis. Genes Dev (2001) 2.15
Evidence for novel fate of Flk1+ progenitor: contribution to muscle lineage. Genesis (2003) 2.14
The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development. Dev Biol (2006) 2.06
Yolk sac angiogenic defect and intra-embryonic apoptosis in mice lacking the Ets-related factor TEL. EMBO J (1997) 2.06
When Ets transcription factors meet their partners. Bioessays (2002) 1.99
A phase and electron microscopic study of vasculogenesis and erythropoiesis in the yolk sac of the mouse. Anat Rec (1971) 1.93
From nuclear transfer to nuclear reprogramming: the reversal of cell differentiation. Annu Rev Cell Dev Biol (2006) 1.91
Mouse models in the study of the Ets family of transcription factors. Oncogene (2000) 1.84
Vasculogenesis and angiogenesis. Cancer Treat Res (2004) 1.83
Foxs and Ets in the transcriptional regulation of endothelial cell differentiation and angiogenesis. Biochim Biophys Acta (2007) 1.79
Efficient direct reprogramming of mature amniotic cells into endothelial cells by ETS factors and TGFβ suppression. Cell (2012) 1.74
Turning straw into gold: directing cell fate for regenerative medicine. Nat Rev Genet (2011) 1.73
Pioneer transcription factors in cell reprogramming. Genes Dev (2014) 1.71
GATA2 functions at multiple steps in hemangioblast development and differentiation. Development (2006) 1.69
Nkx2-5 transactivates the Ets-related protein 71 gene and specifies an endothelial/endocardial fate in the developing embryo. Proc Natl Acad Sci U S A (2009) 1.68
Basic fibroblast growth factor positively regulates hematopoietic development. Development (2000) 1.67
Identification of novel vascular endothelial-specific genes by the microarray analysis of the zebrafish cloche mutants. Blood (2005) 1.64
Combinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouse. Genes Dev (2003) 1.62
Etv2/ER71 induces vascular mesoderm from Flk1+PDGFRα+ primitive mesoderm. Blood (2011) 1.61
Lineage analysis of the hemangioblast as defined by FLK1 and SCL expression. Development (2002) 1.47
In vitro modeling of paraxial and lateral mesoderm differentiation reveals early reversibility. Stem Cells (2005) 1.38
ER71 directs mesodermal fate decisions during embryogenesis. Development (2011) 1.18
Vascular endothelial and endocardial progenitors differentiate as cardiomyocytes in the absence of Etsrp/Etv2 function. Development (2011) 1.17
Etv2 is expressed in the yolk sac hematopoietic and endothelial progenitors and regulates Lmo2 gene expression. Stem Cells (2012) 1.17
ETS transcription factor ETV2 directly converts human fibroblasts into functional endothelial cells. Proc Natl Acad Sci U S A (2014) 1.14
ER71 specifies Flk-1+ hemangiogenic mesoderm by inhibiting cardiac mesoderm and Wnt signaling. Blood (2012) 1.14
Cooperative interaction of Etv2 and Gata2 regulates the development of endothelial and hematopoietic lineages. Dev Biol (2014) 1.05
Regulation of endothelial cell development by ETS transcription factors. Semin Cell Dev Biol (2011) 1.04
Fgf differentially controls cross-antagonism between cardiac and haemangioblast regulators. Development (2011) 1.04
Transcriptional regulation of endothelial cell and vascular development. Circ Res (2013) 1.03
Direct conversion of adult skin fibroblasts to endothelial cells by defined factors. Circulation (2014) 1.02
PKA/CREB signaling triggers initiation of endothelial and hematopoietic cell differentiation via Etv2 induction. Stem Cells (2012) 1.01
Functional analysis of the transcription factor ER71 and its activation of the matrix metalloproteinase-1 promoter. Nucleic Acids Res (2002) 1.00
Ovol2/Movo, a homologue of Drosophila ovo, is required for angiogenesis, heart formation and placental development in mice. Genes Cells (2007) 0.99
Regulation of angiogenesis by ETS transcription factors. Biochem Soc Trans (2009) 0.99
Nkx2-5 represses Gata1 gene expression and modulates the cellular fate of cardiac progenitors during embryogenesis. Circulation (2011) 0.99
Cloning of the murine ER71 gene (Etsrp71) and initial characterization of its promoter. Genomics (2005) 0.98
Endothelialization and altered hematopoiesis by persistent Etv2 expression in mice. Exp Hematol (2012) 0.97
The hemangioblast: a common progenitor of hematopoietic and endothelial cells. J Hematother Stem Cell Res (2002) 0.95
Xenopus er71 is involved in vascular development. Dev Dyn (2010) 0.95
Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2. EMBO Rep (2015) 0.94
ETS transcription factors in hematopoietic stem cell development. Blood Cells Mol Dis (2013) 0.94
Etsrp/Etv2 is directly regulated by Foxc1a/b in the zebrafish angioblast. Circ Res (2011) 0.93
Post-transcriptional mechanisms contribute to Etv2 repression during vascular development. Dev Biol (2013) 0.92
Understanding the role of ETS-mediated gene regulation in complex biological processes. Adv Cancer Res (2013) 0.91
Embryonic vascular endothelial cells are malleable to reprogramming via Prox1 to a lymphatic gene signature. BMC Dev Biol (2010) 0.90
Etv2 and fli1b function together as key regulators of vasculogenesis and angiogenesis. Arterioscler Thromb Vasc Biol (2015) 0.89
Transdifferentiation of fast skeletal muscle into functional endothelium in vivo by transcription factor Etv2. PLoS Biol (2013) 0.89
The Er71 is an important regulator of hematopoietic stem cells in adult mice. Stem Cells (2011) 0.89
Injury-Mediated Vascular Regeneration Requires Endothelial ER71/ETV2. Arterioscler Thromb Vasc Biol (2015) 0.88
Coexpression of platelet-derived growth factor receptor alpha and fetal liver kinase 1 enhances cardiogenic potential in embryonic stem cell differentiation in vitro. J Biosci Bioeng (2007) 0.87