Published in J Mol Histol on December 28, 2015
Epithelial-mesenchymal transitions in development and disease. Cell (2009) 39.17
Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer (2002) 34.99
An overview of epithelio-mesenchymal transformation. Acta Anat (Basel) (1995) 9.18
Epithelial-mesenchymal transitions: the importance of changing cell state in development and disease. J Clin Invest (2009) 6.70
Inhibition of proteasome deubiquitinating activity as a new cancer therapy. Nat Med (2011) 4.09
Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic. Biochim Biophys Acta (2009) 3.55
Ubiquitin-mediated activation of TAK1 and IKK. Oncogene (2007) 3.14
A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response. Cell (2006) 3.10
Relative structural and functional roles of multiple deubiquitylating proteins associated with mammalian 26S proteasome. Mol Biol Cell (2007) 2.28
Deubiquitinase inhibition by small-molecule WP1130 triggers aggresome formation and tumor cell apoptosis. Cancer Res (2010) 2.05
Loss of Usp14 results in reduced levels of ubiquitin in ataxia mice. J Neurochem (2005) 1.71
Epithelial-mesenchymal transition and breast cancer: role, molecular mechanisms and clinical impact. Cancer Treat Rev (2011) 1.63
Targeting ubiquitin specific proteases for drug discovery. Biochimie (2007) 1.45
Deubiquitinases regulate the activity of caspase-1 and interleukin-1β secretion via assembly of the inflammasome. J Biol Chem (2012) 1.40
A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance. Blood (2013) 1.38
The ubiquitin system: pathogenesis of human diseases and drug targeting. Biochim Biophys Acta (2004) 1.32
Clonal diversity in carcinomas: its implications for tumour progression and the contribution made to it by epithelial-mesenchymal transitions. Clin Exp Metastasis (2007) 1.23
Smad ubiquitination regulatory factor 2 promotes metastasis of breast cancer cells by enhancing migration and invasiveness. Cancer Res (2009) 1.22
Proteasome deubiquitinases as novel targets for cancer therapy. Int J Biochem Cell Biol (2012) 1.07
Numbl inhibits glioma cell migration and invasion by suppressing TRAF5-mediated NF-κB activation. Mol Biol Cell (2012) 1.07
Deubiquitination of CXCR4 by USP14 is critical for both CXCL12-induced CXCR4 degradation and chemotaxis but not ERK ativation. J Biol Chem (2008) 1.06
Ubiquitin-specific protease 14 expression in colorectal cancer is associated with liver and lymph node metastases. Oncol Rep (2006) 1.04
Conformational dynamics control ubiquitin-deubiquitinase interactions and influence in vivo signaling. Proc Natl Acad Sci U S A (2013) 0.99
Deubiquitination of Dishevelled by Usp14 is required for Wnt signaling. Oncogenesis (2013) 0.96
Nrf2 pathway regulates multidrug-resistance-associated protein 1 in small cell lung cancer. PLoS One (2013) 0.96
SCYL1BP1 modulates neurite outgrowth and regeneration by regulating the Mdm2/p53 pathway. Mol Biol Cell (2012) 0.93
Over-expression of deubiquitinating enzyme USP14 in lung adenocarcinoma promotes proliferation through the accumulation of β-catenin. Int J Mol Sci (2013) 0.91
The 19S Deubiquitinase inhibitor b-AP15 is enriched in cells and elicits rapid commitment to cell death. Mol Pharmacol (2014) 0.90
Induction of tumor cell apoptosis by a proteasome deubiquitinase inhibitor is associated with oxidative stress. Antioxid Redox Signal (2013) 0.90
Overexpression of forkhead box J2 can decrease the migration of breast cancer cells. J Cell Biochem (2012) 0.88
Neuronal ubiquitin homeostasis. Cell Biochem Biophys (2013) 0.88
PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway. Mol Cancer (2015) 0.87
CD44/CD24 as potential prognostic markers in node-positive invasive ductal breast cancer patients treated with adjuvant chemotherapy. J Mol Histol (2013) 0.87
USP33 mediates Slit-Robo signaling in inhibiting colorectal cancer cell migration. Int J Cancer (2014) 0.86
Ubiquitin C-terminal hydrolase-L1 interacts with adhesion complexes and promotes cell migration, survival, and anchorage independent growth. FASEB J (2012) 0.86
Overexpression of USP14 protease reduces I-κB protein levels and increases cytokine release in lung epithelial cells. J Biol Chem (2013) 0.86
Targeted inhibition of the deubiquitinating enzymes, USP14 and UCHL5, induces proteotoxic stress and apoptosis in Waldenström macroglobulinaemia tumour cells. Br J Haematol (2015) 0.85
Ubiquitin-specific protease 14 (USP14) regulates cellular proliferation and apoptosis in epithelial ovarian cancer. Med Oncol (2014) 0.84
PBK/TOPK mediates geranylgeranylation signaling for breast cancer cell proliferation. Cancer Cell Int (2015) 0.83
Decreased expression and prognostic role of EHD2 in human breast carcinoma: correlation with E-cadherin. J Mol Histol (2015) 0.83
Expression and prognostic role of SGTA in human breast carcinoma correlates with tumor cell proliferation. J Mol Histol (2014) 0.82
USP-11 as a predictive and prognostic factor following neoadjuvant therapy in women with breast cancer. Cancer J (2013) 0.82
Decreased expression of SERPINB1 correlates with tumor invasion and poor prognosis in hepatocellular carcinoma. J Mol Histol (2013) 0.80
Expression and prognostic role of SKIP in human breast carcinoma. J Mol Histol (2013) 0.78
Ubiquitin-specific protease 14 expression associated with intrahepatic cholangiocarcinoma cell differentiation. Asian Pac J Cancer Prev (2011) 0.77