Published in N Engl J Med on January 28, 2016
The Influence of ANS-6637 on Midazolam Pharmacokinetics in Healthy Volunteers | NCT03831971
Effects of Marijuana Use on Brain Structure and Function: Neuroimaging Findings from a Neurodevelopmental Perspective. Int Rev Neurobiol (2016) 0.90
Liking, wanting, and the incentive-sensitization theory of addiction. Am Psychol (2016) 0.80
Proceedings of the Fourth Annual Deep Brain Stimulation Think Tank: A Review of Emerging Issues and Technologies. Front Integr Neurosci (2016) 0.78
Stimulants for the Control of Hedonic Appetite. Front Pharmacol (2016) 0.77
Gene expression profiling in the human alcoholic brain. Neuropharmacology (2017) 0.76
Modelling depression in animals: at the interface of reward and stress pathways. Psychopharmacology (Berl) (2017) 0.76
The natural history of substance use disorders. Curr Opin Psychiatry (2016) 0.76
Individual differences in brain responses to cigarette-related cues and pleasant stimuli in young smokers. Drug Alcohol Depend (2016) 0.76
The role of neuroimmune signaling in alcoholism. Neuropharmacology (2017) 0.76
Good Psychometric Properties of the Addiction Version of the Revised Illness Perception Questionnaire for Health Care Professionals. PLoS One (2016) 0.75
Specific behavioral and cellular adaptations induced by chronic morphine are reduced by dietary omega-3 polyunsaturated fatty acids. PLoS One (2017) 0.75
Insula Demonstrates a Non-Linear Response to Varying Demand for Cognitive Control and Weaker Resting Connectivity With the Executive Control Network in Smokers. Neuropsychopharmacology (2016) 0.75
Beyond Cue Reactivity: Non-Drug-Related Motivationally Relevant Stimuli Are Necessary to Understand Reactivity to Drug-Related Cues. Nicotine Tob Res (2017) 0.75
Gender dimorphism of brain reward system volumes in alcoholism. Psychiatry Res (2017) 0.75
Mothering from the Inside Out: A mentalization-based therapy for mothers in treatment for drug addiction. Int J Birth Parent Educ (2016) 0.75
Treatment of Alcohol Use Disorder in Patients with Alcoholic Liver Disease. Am J Med (2016) 0.75
Pediatric Irritability: A Systems Neuroscience Approach. Trends Cogn Sci (2017) 0.75
Subjective alcohol responses in a cross-sectional, field-based study of adolescents and young adults: Effects of age, drinking level, and dependence/consequences. Drug Alcohol Depend (2016) 0.75
Higher resting-state activity in reward-related brain circuits in obese versus normal-weight females independent of food intake. Int J Obes (Lond) (2016) 0.75
Association of Stimulant Use With Dopaminergic Alterations in Users of Cocaine, Amphetamine, or Methamphetamine: A Systematic Review and Meta-analysis. JAMA Psychiatry (2017) 0.75
Bilateral Transcranial Magnetic Stimulation of the Prefrontal Cortex Reduces Cocaine Intake: A Pilot Study. Front Psychiatry (2016) 0.75
Deficits in autonomic indices of emotion regulation and reward processing associated with prescription opioid use and misuse. Psychopharmacology (Berl) (2016) 0.75
Is biological aging accelerated in drug addiction? Curr Opin Behav Sci (2017) 0.75
Cocaine sensitization increases sub-threshold activity in dopamine neurons from the ventral tegmental area. J Neurophysiol (2016) 0.75
Drug use disorders: impact of a public health rather than a criminal justice approach. World Psychiatry (2017) 0.75
Making the hard work of recovery more attractive for those with substance use disorders. Addiction (2016) 0.75
Craving and Acute Effects of Alcohol in Youths' Daily Lives: Associations With Alcohol Use Disorder Severity. Exp Clin Psychopharmacol (2017) 0.75
Binge Eating Disorder (BED) in Relation to Addictive Behaviors and Personality Risk Factors. Front Psychol (2017) 0.75
Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2. Synapse (2017) 0.75
2017 ASTHO President's Challenge: Public Health Approaches to Preventing Substance Misuse and Addiction. J Public Health Manag Pract (2017) 0.75
Internet gaming disorder: Trends in prevalence 1998-2016. Addict Behav (2017) 0.75
Is Addiction a Brain Disease? Neuroethics (2016) 0.75
Rehabilitating the addicted brain with transcranial magnetic stimulation. Nat Rev Neurosci (2017) 0.75
Extended treatment for cigarette smoking cessation: a randomized control trial. Addiction (2017) 0.75
Beneficial and detrimental effects of genetic explanations for addiction. Int J Soc Psychiatry (2017) 0.75
Hunger and Satiety Gauge Reward Sensitivity. Front Endocrinol (Lausanne) (2017) 0.75
Physical Exercise Interventions for Drug Addictive Disorders. J Reward Defic Syndr Addict Sci (2017) 0.75
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Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications. Nat Rev Neurosci (2011) 4.88
Abuse of prescription drugs and the risk of addiction. Drug Alcohol Depend (2006) 4.24
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A key role for corticotropin-releasing factor in alcohol dependence. Trends Neurosci (2007) 3.16
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Toward understanding the genetics of alcohol drinking through transcriptome meta-analysis. Proc Natl Acad Sci U S A (2006) 3.04
The neurocircuitry of impaired insight in drug addiction. Trends Cogn Sci (2009) 3.01
Initial evidence for the reliability and validity of a "Lite" version of the Addiction Severity Index. Drug Alcohol Depend (2006) 2.89
Prescription opioids, overdose deaths, and physician responsibility. JAMA (2008) 2.83
Neurobiological evidence for hedonic allostasis associated with escalating cocaine use. Nat Neurosci (2002) 2.83
Establishing the feasibility of performance measures for alcohol and other drugs. J Subst Abuse Treat (2002) 2.75
Conditioned withdrawal drives heroin consumption and decreases reward sensitivity. J Neurosci (2006) 2.74
Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats. Biol Psychiatry (2006) 2.70
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Pharmacological evidence for a motivational role of kappa-opioid systems in ethanol dependence. Neuropsychopharmacology (2007) 2.61
Drug addiction: the neurobiology of disrupted self-control. Trends Mol Med (2006) 2.57
Issues for DSM-V: should obesity be included as a brain disorder? Am J Psychiatry (2007) 2.48
Similarity between obesity and drug addiction as assessed by neurofunctional imaging: a concept review. J Addict Dis (2004) 2.45
Partial recovery of brain metabolism in methamphetamine abusers after protracted abstinence. Am J Psychiatry (2004) 2.42
Building a new conceptual framework for receptor heteromers. Nat Chem Biol (2009) 2.41
Measuring meals: structure of prandial food and water intake of rats. Am J Physiol Regul Integr Comp Physiol (2005) 2.32
Evidence of gender differences in the ability to inhibit brain activation elicited by food stimulation. Proc Natl Acad Sci U S A (2009) 2.27
Escalation of methamphetamine self-administration in rats: a dose-effect function. Psychopharmacology (Berl) (2006) 2.24
The role of the dynorphin-kappa opioid system in the reinforcing effects of drugs of abuse. Psychopharmacology (Berl) (2010) 2.19
Exposure to appetitive food stimuli markedly activates the human brain. Neuroimage (2004) 2.13
Prescription OxyContin abuse among patients entering addiction treatment. Am J Psychiatry (2007) 2.07
Severity of neuropsychological impairment in cocaine and alcohol addiction: association with metabolism in the prefrontal cortex. Neuropsychologia (2004) 2.07
Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release plays a key role in alcohol dependence. Biol Psychiatry (2010) 2.04
Effects of stimulant medication on growth rates across 3 years in the MTA follow-up. J Am Acad Child Adolesc Psychiatry (2007) 2.03
CRF-CRF1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats. Proc Natl Acad Sci U S A (2007) 2.01
The gamma-aminobutyric acid-B receptor agonist baclofen attenuates responding for ethanol in ethanol-dependent rats. Alcohol Clin Exp Res (2007) 1.99
Alcohol-related genes: contributions from studies with genetically engineered mice. Addict Biol (2006) 1.95
Corticotropin-releasing factor in brain: a role in activation, arousal, and affect regulation. J Pharmacol Exp Ther (2004) 1.92
Cellular and behavioral interactions of gabapentin with alcohol dependence. J Neurosci (2008) 1.91
Psychopharmacology: concepts and opinions about the use of stimulant medications. J Child Psychol Psychiatry (2009) 1.91
Functional connectivity hubs in the human brain. Neuroimage (2011) 1.87
Physician education in addiction medicine. JAMA (2013) 1.87
Transition to drug addiction: a negative reinforcement model based on an allostatic decrease in reward function. Psychopharmacology (Berl) (2005) 1.82
Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinence. Alcohol (2003) 1.81
Alcohol self-administration acutely stimulates the hypothalamic-pituitary-adrenal axis, but alcohol dependence leads to a dampened neuroendocrine state. Eur J Neurosci (2008) 1.81
Anterior cingulate cortex hypoactivations to an emotionally salient task in cocaine addiction. Proc Natl Acad Sci U S A (2009) 1.79
Status hearings in drug court: when more is less and less is more. Drug Alcohol Depend (2002) 1.78
Association between functional connectivity hubs and brain networks. Cereb Cortex (2011) 1.78
Abnormal functional connectivity in children with attention-deficit/hyperactivity disorder. Biol Psychiatry (2011) 1.76
Treating cocaine addiction with viruses. Proc Natl Acad Sci U S A (2004) 1.75
Neuroimmune regulation of alcohol consumption: behavioral validation of genes obtained from genomic studies. Addict Biol (2011) 1.75
Charting a course for health services research at the National Institute on Drug Abuse. J Subst Abuse Treat (2005) 1.74
Neuroscience networks: data-sharing in an information age. PLoS Biol (2003) 1.74
Lack of self-administration of cocaine in dopamine D1 receptor knock-out mice. J Neurosci (2007) 1.73
Cost-effectiveness analysis of addiction treatment: paradoxes of multiple outcomes. Drug Alcohol Depend (2004) 1.73
Stress enhancement of craving during sobriety: a risk for relapse. Alcohol Clin Exp Res (2005) 1.71
alpha1-noradrenergic receptor antagonism blocks dependence-induced increases in responding for ethanol. Alcohol (2008) 1.71
Consensus statement on office-based treatment of opioid dependence using buprenorphine. J Subst Abuse Treat (2004) 1.70
Gastric distention activates satiety circuitry in the human brain. Neuroimage (2007) 1.68
The role of dopamine in motivation for food in humans: implications for obesity. Expert Opin Ther Targets (2002) 1.66
Corticosteroid-dependent plasticity mediates compulsive alcohol drinking in rats. J Neurosci (2012) 1.65
Dependence-induced increases in ethanol self-administration in mice are blocked by the CRF1 receptor antagonist antalarmin and by CRF1 receptor knockout. Pharmacol Biochem Behav (2007) 1.63
The neuropsychology of cocaine addiction: recent cocaine use masks impairment. Neuropsychopharmacology (2008) 1.63
Understanding the effects of stimulant medications on cognition in individuals with attention-deficit hyperactivity disorder: a decade of progress. Neuropsychopharmacology (2010) 1.62
Individual differences in prefrontal cortex function and the transition from drug use to drug dependence. Neurosci Biobehav Rev (2010) 1.61
Decreased brain dopaminergic transporters in HIV-associated dementia patients. Brain (2004) 1.61
Self-help organizations for alcohol and drug problems: toward evidence-based practice and policy. J Subst Abuse Treat (2004) 1.59
DATStats: results from 85 studies using the Drug Abuse Treatment Cost Analysis Program. J Subst Abuse Treat (2003) 1.58
Systemic κ-opioid receptor antagonism by nor-binaltorphimine reduces dependence-induced excessive alcohol self-administration in rats. Addict Biol (2011) 1.58
CRF system recruitment mediates dark side of compulsive eating. Proc Natl Acad Sci U S A (2009) 1.57
Monoamine oxidase and cigarette smoking. Neurotoxicology (2003) 1.57
Medicine. Spatial turn in health research. Science (2013) 1.57
Preclinical studies of alcohol binge drinking. Ann N Y Acad Sci (2011) 1.56
Allostasis and dysregulation of corticotropin-releasing factor and neuropeptide Y systems: implications for the development of alcoholism. Pharmacol Biochem Behav (2004) 1.56
Comparison of monoamine oxidase a in peripheral organs in nonsmokers and smokers. J Nucl Med (2005) 1.53
Monoamine oxidase inhibition dramatically increases the motivation to self-administer nicotine in rats. J Neurosci (2005) 1.53
Enhanced striatal dopamine release during food stimulation in binge eating disorder. Obesity (Silver Spring) (2011) 1.52
Escalation of cocaine self-administration does not depend on altered cocaine-induced nucleus accumbens dopamine levels. J Neurochem (2003) 1.52
How are addicted physicians treated? A national survey of Physician Health Programs. J Subst Abuse Treat (2009) 1.52
Dopamine transporters in striatum correlate with deactivation in the default mode network during visuospatial attention. PLoS One (2009) 1.51
Brain monoamine oxidase A activity predicts trait aggression. J Neurosci (2008) 1.51
Drug addiction: pathways to the disease and pathophysiological perspectives. Eur Neuropsychopharmacol (2006) 1.48
Subjective sensitivity to monetary gradients is associated with frontolimbic activation to reward in cocaine abusers. Drug Alcohol Depend (2006) 1.48
Benefit-cost analysis of addiction treatment: methodological guidelines and empirical application using the DATCAP and ASI. Health Serv Res (2002) 1.48
Integrating addiction medicine into graduate medical education in primary care: the time has come. Ann Intern Med (2011) 1.47
A vaccine strategy that induces protective immunity against heroin. J Med Chem (2011) 1.47
Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats. Psychopharmacology (Berl) (2004) 1.47
Gastric stimulation in obese subjects activates the hippocampus and other regions involved in brain reward circuitry. Proc Natl Acad Sci U S A (2006) 1.46
The therapeutic potential of CRF1 antagonists for anxiety. Expert Opin Investig Drugs (2004) 1.46
Diminished nicotine withdrawal in adolescent rats: implications for vulnerability to addiction. Psychopharmacology (Berl) (2006) 1.45
Imaging the addicted human brain. Sci Pract Perspect (2007) 1.45
Nicotine withdrawal in adolescent and adult rats. Ann N Y Acad Sci (2004) 1.44
Thalamo-cortical dysfunction in cocaine abusers: implications in attention and perception. Psychiatry Res (2007) 1.44