Published in Nucleic Acids Res on February 04, 2016
Concurrent micro-RNA mediated silencing of tick-borne flavivirus replication in tick vector and in the brain of vertebrate host. Sci Rep (2016) 0.81
Viral RNA switch mediates the dynamic control of flavivirus replicase recruitment by genome cyclization. Elife (2016) 0.77
Synergistic Internal Ribosome Entry Site/MicroRNA-Based Approach for Flavivirus Attenuation and Live Vaccine Development. MBio (2017) 0.75
Functional Information Stored in the Conserved Structural RNA Domains of Flavivirus Genomes. Front Microbiol (2017) 0.75
MicroRNAs: target recognition and regulatory functions. Cell (2009) 92.17
Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res (2003) 77.89
MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell (2007) 38.42
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet (2008) 32.08
Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol (2004) 15.15
The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol Cell (2007) 7.99
Regulation of miRNA expression during neural cell specification. Eur J Neurosci (2005) 5.27
Biological basis for restriction of microRNA targets to the 3' untranslated region in mammalian mRNAs. Nat Struct Mol Biol (2009) 3.70
A virus resembling Russian spring-summer encephalitis virus from an ixodid tick in Malaya. Nature (1956) 3.53
Essential role of cyclization sequences in flavivirus RNA replication. J Virol (2001) 3.31
Conserved elements in the 3' untranslated region of flavivirus RNAs and potential cyclization sequences. J Mol Biol (1987) 3.30
MicroRNA expression in the adult mouse central nervous system. RNA (2008) 3.12
A highly structured, nuclease-resistant, noncoding RNA produced by flaviviruses is required for pathogenicity. Cell Host Microbe (2008) 2.93
Long-range RNA-RNA interactions circularize the dengue virus genome. J Virol (2005) 2.48
Tick-borne encephalitis. Antiviral Res (2003) 2.25
Role of RNA structures present at the 3'UTR of dengue virus on translation, RNA synthesis, and viral replication. Virology (2005) 2.21
Yellow fever vaccine. Expert Rev Vaccines (2005) 2.13
Spontaneous and engineered deletions in the 3' noncoding region of tick-borne encephalitis virus: construction of highly attenuated mutants of a flavivirus. J Virol (1998) 2.11
Cleavage of protein prM is necessary for infection of BHK-21 cells by tick-borne encephalitis virus. J Gen Virol (2003) 1.90
Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness. Science (2015) 1.82
Conserved RNA secondary structures in Flaviviridae genomes. J Gen Virol (2004) 1.81
Chimeric tick-borne encephalitis and dengue type 4 viruses: effects of mutations on neurovirulence in mice. J Virol (1993) 1.72
Fine mapping of a cis-acting sequence element in yellow fever virus RNA that is required for RNA replication and cyclization. J Virol (2003) 1.68
Attenuation of the Langat tick-borne flavivirus by chimerization with mosquito-borne flavivirus dengue type 4. Proc Natl Acad Sci U S A (1998) 1.60
RNA structures required for production of subgenomic flavivirus RNA. J Virol (2010) 1.52
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro. Proc Natl Acad Sci U S A (2012) 1.48
Functional analysis of dengue virus cyclization sequences located at the 5' and 3'UTRs. Virology (2008) 1.47
Replication in cells of hematopoietic origin is necessary for Dengue virus dissemination. PLoS Pathog (2012) 1.44
West Nile virus genome cyclization and RNA replication require two pairs of long-distance RNA interactions. Virology (2008) 1.37
Interplay of RNA elements in the dengue virus 5' and 3' ends required for viral RNA replication. J Virol (2010) 1.31
Functional analysis of the tick-borne encephalitis virus cyclization elements indicates major differences between mosquito-borne and tick-borne flaviviruses. J Virol (2006) 1.28
Infection, dissemination, and transmission of a West Nile virus green fluorescent protein infectious clone by Culex pipiens quinquefasciatus mosquitoes. Vector Borne Zoonotic Dis (2010) 1.23
A new strategy in design of +RNA virus infectious clones enabling their stable propagation in E. coli. Virology (2001) 1.22
Infectious cDNA clones of Langat tick-borne flavivirus that differ from their parent in peripheral neurovirulence. Virology (2000) 1.21
Construction and characterization of recombinant flaviviruses bearing insertions between E and NS1 genes. Virol J (2007) 1.20
Functional RNA elements in the dengue virus genome. Viruses (2011) 1.11
Infectious cDNA clone of attenuated Langat tick-borne flavivirus (strain E5) and a 3' deletion mutant constructed from it exhibit decreased neuroinvasiveness in immunodeficient mice. Virology (2001) 1.10
Production of pseudoinfectious yellow fever virus with a two-component genome. J Virol (2007) 1.09
MicroRNA targeting of neurotropic flavivirus: effective control of virus escape and reversion to neurovirulent phenotype. J Virol (2012) 1.05
Insertion of microRNA targets into the flavivirus genome alters its highly neurovirulent phenotype. J Virol (2010) 1.02
Tick-borne flaviviruses. Clin Lab Med (2010) 0.98
Analysis of the effects of alterations in the tick-borne encephalitis virus 3'-noncoding region on translation and RNA replication using reporter replicons. Virology (2008) 0.95
Vaccination of human volunteers against Russian spring-summer (RSS) virus complex with attenuated Langat E5 virus. Bull World Health Organ (1970) 0.95
MiR-9 promotes microglial activation by targeting MCPIP1. Nat Commun (2014) 0.94
A novel coding-region RNA element modulates infectious dengue virus particle production in both mammalian and mosquito cells and regulates viral replication in Aedes aegypti mosquitoes. Virology (2012) 0.94
Novel cis-acting element within the capsid-coding region enhances flavivirus viral-RNA replication by regulating genome cyclization. J Virol (2013) 0.90
Replication enhancer elements within the open reading frame of tick-borne encephalitis virus and their evolution within the Flavivirus genus. Nucleic Acids Res (2011) 0.87
Overlapping local and long-range RNA-RNA interactions modulate dengue virus genome cyclization and replication. J Virol (2015) 0.86
Dual miRNA targeting restricts host range and attenuates neurovirulence of flaviviruses. PLoS Pathog (2015) 0.84
Functions of the 3' and 5' genome RNA regions of members of the genus Flavivirus. Virus Res (2015) 0.83
Molecular archaeology of Flaviviridae untranslated regions: duplicated RNA structures in the replication enhancer of flaviviruses and pestiviruses emerged via convergent evolution. PLoS One (2014) 0.83
A novel principle of attenuation for the development of new generation live flavivirus vaccines. Arch Virol Suppl (2004) 0.83
Molecular hydrogen regulates the expression of miR-9, miR-21 and miR-199 in LPS-activated retinal microglia cells. Int J Ophthalmol (2013) 0.83
Silencing of neurotropic flavivirus replication in the central nervous system by combining multiple microRNA target insertions in two distinct viral genome regions. Virology (2014) 0.82
Mutational analysis of three predicted 5'-proximal stem-loop structures in the genome of tick-borne encephalitis virus indicates different roles in RNA replication and translation. Virology (2011) 0.80
Robust machine learning algorithms predict microRNA genes and targets. Methods Enzymol (2007) 0.76