Relationship of endothelin-1 and NLRP3 inflammasome activation in HT22 hippocampal cells in diabetes.

PubWeight™: 0.79‹?›

🔗 View Article (PMID 26883974)

Published in Life Sci on February 13, 2016

Authors

Rebecca Ward1, Adviye Ergul2

Author Affiliations

1: Department of Neuroscience and Regenerative Medicine, Augusta University, United States.
2: Department of Physiology, Augusta University, United States; Charlie Norwood Veterans Administration Medical Center, Augusta, GA, United States. Electronic address: aergul@gru.edu.

Articles cited by this

Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke (2011) 10.11

Cognitive dysfunction and diabetes mellitus. Endocr Rev (2008) 3.17

Diabetes and cognitive dysfunction. Lancet (2012) 2.32

Elevated plasma endothelin in patients with diabetes mellitus. Diabetologia (1990) 1.58

Do you know the sex of your cells? Am J Physiol Cell Physiol (2013) 1.49

Endothelin mediates superoxide production and vasoconstriction through activation of NADPH oxidase and uncoupled nitric-oxide synthase in the rat aorta. J Pharmacol Exp Ther (2005) 1.28

Inflammasomes in neuroinflammation and changes in brain function: a focused review. Front Neurosci (2014) 1.26

Activation and regulation of cellular inflammasomes: gaps in our knowledge for central nervous system injury. J Cereb Blood Flow Metab (2014) 1.20

Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory. Genes Brain Behav (2008) 1.09

Mechanisms underlying enhanced contractile response to endothelin-1 in diabetic rat basilar artery. Peptides (2004) 0.99

Cerebral neovascularization and remodeling patterns in two different models of type 2 diabetes. PLoS One (2013) 0.98

Thioredoxin-interacting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet. Diabetologia (2013) 0.98

Endothelin-1, the unfolded protein response, and persistent inflammation: role of pulmonary artery smooth muscle cells. Am J Respir Cell Mol Biol (2012) 0.95

Dual endothelin receptor antagonism with bosentan reverses established vascular remodeling and dysfunctional angiogenesis in diabetic rats: relevance to glycemic control. Life Sci (2014) 0.94

A spontaneously immortalized mouse microglial cell line expressing CD4. Brain Res Dev Brain Res (1996) 0.94

Nod-like receptor protein 1 inflammasome mediates neuron injury under high glucose. Mol Neurobiol (2013) 0.92

Late dual endothelin receptor blockade with bosentan restores impaired cerebrovascular function in diabetes. Life Sci (2014) 0.91

Inhibition of autophagy induces IL-1β release from ARPE-19 cells via ROS mediated NLRP3 inflammasome activation under high glucose stress. Biochem Biophys Res Commun (2015) 0.89

Transgenic mice over-expressing endothelial endothelin-1 show cognitive deficit with blood-brain barrier breakdown after transient ischemia with long-term reperfusion. Neurobiol Learn Mem (2013) 0.89

Cellular distribution of the endothelin system in the human brain. J Chem Neuroanat (2004) 0.88

Endothelin receptor type B agonist, IRL-1620, prevents beta amyloid (Aβ) induced oxidative stress and cognitive impairment in normal and diabetic rats. Pharmacol Biochem Behav (2014) 0.84

Evidence for cortical neuronal loss in male type 2 diabetic Goto-Kakizaki rats. J Alzheimers Dis (2014) 0.84

Inflammatory responses after endothelin B (ETB) receptor activation in human monocytes: new evidence for beneficial anti-inflammatory potency of ETB-receptor antagonism. Pulm Pharmacol Ther (2008) 0.83

Astrocytic and microglial response in experimentally induced diabetic rat brain. Metab Brain Dis (2014) 0.81

Endothelin-A receptor antagonists prevent amyloid-β-induced increase in ETA receptor expression, oxidative stress, and cognitive impairment. J Alzheimers Dis (2011) 0.80

Expression of NLRP3 inflammasome, cytokines and vascular mediators in the skin of systemic sclerosis patients. Isr Med Assoc J (2015) 0.79

Effects of exposure to high glucose on primary cultured hippocampal neurons: involvement of intracellular ROS accumulation. Neurol Sci (2013) 0.79

Efficacy of bosentan, a dual ETA and ETB endothelin receptor antagonist, in experimental diabetes induced vascular endothelial dysfunction and associated dementia in rats. Pharmacol Biochem Behav (2014) 0.78

Flavonol-rich dark cocoa significantly decreases plasma endothelin-1 and improves cognition in urban children. Front Pharmacol (2013) 0.78

Endothelin 1 protects HN33 cells from serum deprivation-induced neuronal apoptosis through Ca(2+)-PKCalpha-ERK pathway. Exp Mol Med (2008) 0.78

Articles by these authors

Variations on a theme: ET-14 notes from mentor and trainees. Life Sci (2016) 0.75