Published in Elife on February 27, 2016
The synaptonemal complex has liquid crystalline properties and spatially regulates meiotic recombination factors. Elife (2017) 0.76
Ndrg3 gene regulates DSB repair during meiosis through modulation the ERK signal pathway in the male germ cells. Sci Rep (2017) 0.75
Signaling-Mediated Regulation of Meiotic Prophase I and Transition During Oogenesis. Results Probl Cell Differ (2017) 0.75
The genetics of Caenorhabditis elegans. Genetics (1974) 102.14
An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J Am Soc Mass Spectrom (1994) 45.51
In-gel digestion for mass spectrometric characterization of proteins and proteomes. Nat Protoc (2006) 16.56
Proteomics. Tissue-based map of the human proteome. Science (2015) 10.21
A tissue-specific atlas of mouse protein phosphorylation and expression. Cell (2010) 8.65
Single-copy insertion of transgenes in Caenorhabditis elegans. Nat Genet (2008) 7.58
Heritable genome editing in C. elegans via a CRISPR-Cas9 system. Nat Methods (2013) 5.93
Genome-wide germline-enriched and sex-biased expression profiles in Caenorhabditis elegans. Development (2003) 4.61
GPS 2.0, a tool to predict kinase-specific phosphorylation sites in hierarchy. Mol Cell Proteomics (2008) 4.33
Chromosome choreography: the meiotic ballet. Science (2003) 4.00
Synapsis-dependent and -independent mechanisms stabilize homolog pairing during meiotic prophase in C. elegans. Genes Dev (2002) 3.63
Synaptonemal complex assembly in C. elegans is dispensable for loading strand-exchange proteins but critical for proper completion of recombination. Dev Cell (2003) 3.53
A putative exchange factor for Rho1 GTPase is required for initiation of cytokinesis in Drosophila. Genes Dev (1999) 3.25
Three genes of the MAP kinase cascade, mek-2, mpk-1/sur-1 and let-60 ras, are required for meiotic cell cycle progression in Caenorhabditis elegans. Development (1995) 2.69
KinasePhos 2.0: a web server for identifying protein kinase-specific phosphorylation sites based on sequences and coupling patterns. Nucleic Acids Res (2007) 2.69
c(3)G encodes a Drosophila synaptonemal complex protein. Genes Dev (2001) 2.68
Mouse Sycp1 functions in synaptonemal complex assembly, meiotic recombination, and XY body formation. Genes Dev (2005) 2.38
Oncogene ect2 is related to regulators of small GTP-binding proteins. Nature (1993) 2.34
Synaptonemal complex (SC) component Zip1 plays a role in meiotic recombination independent of SC polymerization along the chromosomes. Proc Natl Acad Sci U S A (1996) 2.29
COSA-1 reveals robust homeostasis and separable licensing and reinforcement steps governing meiotic crossovers. Cell (2012) 2.10
Confident phosphorylation site localization using the Mascot Delta Score. Mol Cell Proteomics (2010) 1.90
Heteroduplex DNA formation and homolog pairing in yeast meiotic mutants. Genetics (1995) 1.90
HTP-1-dependent constraints coordinate homolog pairing and synapsis and promote chiasma formation during C. elegans meiosis. Genes Dev (2005) 1.89
Galphao/i and Galphas signaling function in parallel with the MSP/Eph receptor to control meiotic diapause in C. elegans. Curr Biol (2006) 1.88
"Holo"er than thou: chromosome segregation and kinetochore function in C. elegans. Chromosome Res (2004) 1.88
Condensin restructures chromosomes in preparation for meiotic divisions. J Cell Biol (2004) 1.85
Sequential functioning of the ECT-2 RhoGEF, RHO-1 and CDC-42 establishes cell polarity in Caenorhabditis elegans embryos. Nat Cell Biol (2006) 1.79
HTP-3 links DSB formation with homolog pairing and crossing over during C. elegans meiosis. Dev Cell (2008) 1.76
Multiple functions and dynamic activation of MPK-1 extracellular signal-regulated kinase signaling in Caenorhabditis elegans germline development. Genetics (2007) 1.73
Heritable custom genomic modifications in Caenorhabditis elegans via a CRISPR-Cas9 system. Genetics (2013) 1.72
Polo-like kinase Cdc5 drives exit from pachytene during budding yeast meiosis. Genes Dev (2008) 1.66
ZHP-3 acts at crossovers to couple meiotic recombination with synaptonemal complex disassembly and bivalent formation in C. elegans. PLoS Genet (2008) 1.64
Synaptonemal complex-dependent centromeric clustering and the initiation of synapsis in Drosophila oocytes. Curr Biol (2011) 1.62
HSP70-2 is required for desynapsis of synaptonemal complexes during meiotic prophase in juvenile and adult mouse spermatocytes. Development (1997) 1.61
Crossing over is coupled to late meiotic prophase bivalent differentiation through asymmetric disassembly of the SC. J Cell Biol (2005) 1.55
Caenorhabditis elegans HIM-18/SLX-4 interacts with SLX-1 and XPF-1 and maintains genomic integrity in the germline by processing recombination intermediates. PLoS Genet (2009) 1.52
Multiple ERK substrates execute single biological processes in Caenorhabditis elegans germ-line development. Proc Natl Acad Sci U S A (2009) 1.50
Crossovers trigger a remodeling of meiotic chromosome axis composition that is linked to two-step loss of sister chromatid cohesion. Genes Dev (2008) 1.48
Distribution of meiotic recombination events: talking to your neighbors. Curr Opin Genet Dev (2009) 1.46
Deformations within moving kinetochores reveal different sites of active and passive force generation. Science (2012) 1.36
A targeted RNAi screen for genes involved in chromosome morphogenesis and nuclear organization in the Caenorhabditis elegans germline. Genetics (2002) 1.35
SYP-3 restricts synaptonemal complex assembly to bridge paired chromosome axes during meiosis in Caenorhabditis elegans. Genetics (2007) 1.34
LAB-1 antagonizes the Aurora B kinase in C. elegans. Genes Dev (2008) 1.29
Rho exchange factor ECT2 is induced by growth factors and regulates cytokinesis through the N-terminal cell cycle regulator-related domains. J Cell Biochem (2003) 1.29
The chromosome axis controls meiotic events through a hierarchical assembly of HORMA domain proteins. Dev Cell (2014) 1.28
The guanine nucleotide exchange factor (GEF) Ect2 is an oncogene in human cancer. Adv Enzyme Regul (2009) 1.28
Synaptonemal complex components persist at centromeres and are required for homologous centromere pairing in mouse spermatocytes. PLoS Genet (2012) 1.28
Interplay between synaptonemal complex, homologous recombination, and centromeres during mammalian meiosis. PLoS Genet (2012) 1.22
The many facets of SC function during C. elegans meiosis. Chromosoma (2006) 1.22
Coordinating cohesion, co-orientation, and congression during meiosis: lessons from holocentric chromosomes. Genes Dev (2010) 1.20
Synapsis-defective mutants reveal a correlation between chromosome conformation and the mode of double-strand break repair during Caenorhabditis elegans meiosis. Genetics (2007) 1.19
The C.elegans MAPK phosphatase LIP-1 is required for the G(2)/M meiotic arrest of developing oocytes. EMBO J (2002) 1.15
C. elegans GLA-3 is a novel component of the MAP kinase MPK-1 signaling pathway required for germ cell survival. Genes Dev (2006) 1.15
The synaptonemal complex protein, Zip1, promotes the segregation of nonexchange chromosomes at meiosis I. Proc Natl Acad Sci U S A (2009) 1.14
The fidelity of synaptonemal complex assembly is regulated by a signaling mechanism that controls early meiotic progression. Dev Cell (2014) 1.13
A yeast two-hybrid screen for SYP-3 interactors identifies SYP-4, a component required for synaptonemal complex assembly and chiasma formation in Caenorhabditis elegans meiosis. PLoS Genet (2009) 1.10
Involvement of epithelial cell transforming sequence-2 oncoantigen in lung and esophageal cancer progression. Clin Cancer Res (2009) 1.09
Mutations in the chromosomal passenger complex and the condensin complex differentially affect synaptonemal complex disassembly and metaphase I configuration in Drosophila female meiosis. Genetics (2008) 1.07
The synaptonemal complex protein Zip1 promotes bi-orientation of centromeres at meiosis I. PLoS Genet (2009) 1.07
Canonical RTK-Ras-ERK signaling and related alternative pathways. WormBook (2013) 1.03
The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage. PLoS One (2011) 1.02
Regulation of Caenorhabditis elegans p53/CEP-1-dependent germ cell apoptosis by Ras/MAPK signaling. PLoS Genet (2011) 1.00
MPK-1 ERK controls membrane organization in C. elegans oogenesis via a sex-determination module. Dev Cell (2011) 0.99
The Caenorhabditis elegans ect-2 RhoGEF gene regulates cytokinesis and migration of epidermal P cells. EMBO Rep (2005) 0.97
Full-length synaptonemal complex grows continuously during meiotic prophase in budding yeast. PLoS Genet (2012) 0.96
DNA damage during meiosis induces chromatin remodeling and synaptonemal complex disassembly. Dev Cell (2011) 0.95
Polo-like kinase is required for synaptonemal complex disassembly and phosphorylation in mouse spermatocytes. J Cell Sci (2012) 0.91
Ipl1/Aurora B kinase coordinates synaptonemal complex disassembly with cell cycle progression and crossover formation in budding yeast meiosis. Genes Dev (2009) 0.89
The Caenorhabditis elegans homologue of the proto-oncogene ect-2 positively regulates RAS signalling during vulval development. EMBO Rep (2005) 0.88
akirin is required for diakinesis bivalent structure and synaptonemal complex disassembly at meiotic prophase I. Mol Biol Cell (2013) 0.86
ERK pathway inhibitors: how low should we go? Cancer Discov (2013) 0.85
Mammalian CNTD1 is critical for meiotic crossover maturation and deselection of excess precrossover sites. J Cell Biol (2014) 0.84
RNA stimulates Aurora B kinase activity during mitosis. PLoS One (2014) 0.84
Mechanisms of CDC-42 activation during contact-induced cell polarization. J Cell Sci (2013) 0.84
LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion. PLoS Biol (2012) 0.84
Environmental stress affects the activity of metabolic and growth factor signaling networks and induces autophagy markers in MCF7 breast cancer cells. Mol Cell Proteomics (2014) 0.82
Mitogen-activated protein kinase dynamics during the meiotic G2/MI transition of mouse spermatocytes. Biol Reprod (2004) 0.82
QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology. Elife (2015) 0.93
Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis. Elife (2015) 0.90
Polo-like kinase-dependent phosphorylation of the synaptonemal complex protein SYP-4 regulates double-strand break formation through a negative feedback loop. Elife (2017) 0.76
Cohesin-interacting protein WAPL-1 regulates meiotic chromosome structure and cohesion by antagonizing specific cohesin complexes. Elife (2016) 0.76
QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease. Elife (2016) 0.75
Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response. Nat Commun (2016) 0.75
Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1. Sci Rep (2017) 0.75
A MIG-15/JNK-1 MAP kinase cascade opposes RPM-1 signaling in synapse formation and learning. PLoS Genet (2017) 0.75