Published in J Lipid Res on February 26, 2016
Transformation of intact yeast cells treated with alkali cations. J Bacteriol (1983) 100.26
One-step gene disruption in yeast. Methods Enzymol (1983) 52.81
Development and validation of a genetic algorithm for flexible docking. J Mol Biol (1997) 14.36
Extra precision glide: docking and scoring incorporating a model of hydrophobic enclosure for protein-ligand complexes. J Med Chem (2006) 8.75
Phosphoinositide kinases. Annu Rev Biochem (1998) 8.51
Membrane recognition by phospholipid-binding domains. Nat Rev Mol Cell Biol (2008) 7.43
Plasma membrane phosphoinositide organization by protein electrostatics. Nature (2005) 6.32
An essential role for a phospholipid transfer protein in yeast Golgi function. Nature (1990) 4.63
The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex. J Cell Biol (1989) 3.55
Structural mechanism for sterol sensing and transport by OSBP-related proteins. Nature (2005) 3.22
Mutations in the CDP-choline pathway for phospholipid biosynthesis bypass the requirement for an essential phospholipid transfer protein. Cell (1991) 3.16
SAC1-like domains of yeast SAC1, INP52, and INP53 and of human synaptojanin encode polyphosphoinositide phosphatases. J Biol Chem (1999) 2.75
Mutations in the SAC1 gene suppress defects in yeast Golgi and yeast actin function. J Cell Biol (1989) 2.49
Osh4p exchanges sterols for phosphatidylinositol 4-phosphate between lipid bilayers. J Cell Biol (2011) 2.22
An integrated platform of genomic assays reveals small-molecule bioactivities. Nat Chem Biol (2008) 2.21
Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae. Biochim Biophys Acta (2007) 2.08
Analysis of oxysterol binding protein homologue Kes1p function in regulation of Sec14p-dependent protein transport from the yeast Golgi complex. J Cell Biol (2002) 2.07
Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol-transfer protein. Nature (1998) 2.00
Kes1p shares homology with human oxysterol binding protein and participates in a novel regulatory pathway for yeast Golgi-derived transport vesicle biogenesis. EMBO J (1996) 1.89
Inositol-lipid binding motifs: signal integrators through protein-lipid and protein-protein interactions. J Cell Sci (2005) 1.88
Functional anatomy of phospholipid binding and regulation of phosphoinositide homeostasis by proteins of the sec14 superfamily. Mol Cell (2008) 1.82
Transcriptional control of the yeast PDR5 gene by the PDR3 gene product. Mol Cell Biol (1994) 1.77
The reference genome sequence of Saccharomyces cerevisiae: then and now. G3 (Bethesda) (2014) 1.68
Identification of a novel family of nonclassic yeast phosphatidylinositol transfer proteins whose function modulates phospholipase D activity and Sec14p-independent cell growth. Mol Biol Cell (2000) 1.66
Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects. Proc Natl Acad Sci U S A (1998) 1.65
Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy. Mol Biol Cell (1999) 1.55
The Sec14 superfamily and mechanisms for crosstalk between lipid metabolism and lipid signaling. Trends Biochem Sci (2009) 1.46
Mapping the cellular response to small molecules using chemogenomic fitness signatures. Science (2014) 1.39
Phosphatidylinositol-4-phosphate 5-kinase isozymes catalyze the synthesis of 3-phosphate-containing phosphatidylinositol signaling molecules. J Biol Chem (1997) 1.32
Phosphatidylinositol transfer proteins and cellular nanoreactors for lipid signaling. Nat Chem Biol (2006) 1.19
Nonclassical PITPs activate PLD via the Stt4p PtdIns-4-kinase and modulate function of late stages of exocytosis in vegetative yeast. Traffic (2005) 1.09
Resurrection of a functional phosphatidylinositol transfer protein from a pseudo-Sec14 scaffold by directed evolution. Mol Biol Cell (2011) 0.93
A phosphatidylinositol transfer protein integrates phosphoinositide signaling with lipid droplet metabolism to regulate a developmental program of nutrient stress-induced membrane biogenesis. Mol Biol Cell (2014) 0.91
Mammalian diseases of phosphatidylinositol transfer proteins and their homologs. Clin Lipidol (2010) 0.89
PITPs as targets for selectively interfering with phosphoinositide signaling in cells. Nat Chem Biol (2013) 0.86
Phosphatidylinositol transfer proteins and instructive regulation of lipid kinase biology. Biochim Biophys Acta (2015) 0.85
2-Alkyloxazoles as potent and selective PI4KIIIβ inhibitors demonstrating inhibition of HCV replication. Bioorg Med Chem Lett (2014) 0.80
Acute manipulation of phosphoinositide levels in cells. Methods Cell Biol (2012) 0.77