Published in Cancer Res on March 01, 2016
Rab25 acts as an oncogene in luminal B breast cancer and is causally associated with Snail driven EMT. Oncotarget (2016) 0.81
Rab-mediated vesicle trafficking in cancer. J Biomed Sci (2016) 0.78
Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion. Nat Commun (2017) 0.75
Rab11-FIP1 phosphorylation by MARK2 regulates polarity in MDCK cells. Cell Logist (2017) 0.75
Rab25 GTPase: Functional roles in cancer. Oncotarget (2017) 0.75
The cre-inducer doxycycline lowers cytokine and chemokine transcript levels in the gut of mice. J Appl Genet (2017) 0.75
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A (2001) 71.82
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science (1987) 49.88
Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer. Science (1989) 31.55
Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype. Cancer Res (2008) 6.95
The biology of erbB-2/neu/HER-2 and its role in cancer. Biochim Biophys Acta (1994) 4.92
Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis. Cancer Cell (2006) 4.15
Rab25 associates with alpha5beta1 integrin to promote invasive migration in 3D microenvironments. Dev Cell (2007) 3.84
Elevated expression of activated forms of Neu/ErbB-2 and ErbB-3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer. EMBO J (1999) 3.79
A novel doxycycline-inducible system for the transgenic analysis of mammary gland biology. FASEB J (2002) 3.05
Triple-negative breast cancer--current status and future directions. Ann Oncol (2009) 2.78
Rab-coupling protein coordinates recycling of alpha5beta1 integrin and EGFR1 to promote cell migration in 3D microenvironments. J Cell Biol (2008) 2.61
The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density. J Cell Biol (2003) 2.21
Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression. Breast Cancer Res (2011) 1.96
Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progression. Dev Cell (2011) 1.87
Reduced E-cadherin expression is associated with invasiveness and unfavorable prognosis in breast cancer. Am J Clin Pathol (1996) 1.86
ShcA signalling is essential for tumour progression in mouse models of human breast cancer. EMBO J (2008) 1.82
The integrin-linked kinase regulates the cyclin D1 gene through glycogen synthase kinase 3beta and cAMP-responsive element-binding protein-dependent pathways. J Biol Chem (2000) 1.77
RCP is a human breast cancer-promoting gene with Ras-activating function. J Clin Invest (2009) 1.71
Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer. Mol Cell Biol (2001) 1.68
Distinct tyrosine autophosphorylation sites negatively and positively modulate neu-mediated transformation. Mol Cell Biol (1997) 1.66
Overexpression of fatty acid synthase gene activates HER1/HER2 tyrosine kinase receptors in human breast epithelial cells. Cell Prolif (2008) 1.65
Expression and functional role of E- and P-cadherins in mouse mammary ductal morphogenesis and growth. Dev Biol (1995) 1.63
Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion. Oncogene (2012) 1.62
Loss of the 14-3-3σ tumor suppressor is a critical event in ErbB2-mediated tumor progression. Cancer Discov (2011) 1.57
Endocytosis of receptor tyrosine kinases. Cold Spring Harb Perspect Biol (2013) 1.57
Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin. Oncogene (2006) 1.55
Signal transduction in mammary tumorigenesis: a transgenic perspective. Oncogene (2000) 1.46
Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2. Cell Stress Chaperones (2002) 1.37
Loss of Rab25 promotes the development of intestinal neoplasia in mice and is associated with human colorectal adenocarcinomas. J Clin Invest (2010) 1.35
Multiple ErbB-2/Neu Phosphorylation Sites Mediate Transformation through Distinct Effector Proteins. J Biol Chem (2001) 1.29
Tumor suppressor function of Rab25 in triple-negative breast cancer. Int J Cancer (2010) 1.28
ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells. J Am Soc Nephrol (2010) 1.20
Loss of E-cadherin expression associated with lymph node metastases in small breast carcinomas. Virchows Arch (1997) 1.12
Rab25 as a tumour suppressor in colon carcinogenesis. Br J Cancer (2010) 1.10
Rab25 is a tumor suppressor gene with antiangiogenic and anti-invasive activities in esophageal squamous cell carcinoma. Cancer Res (2012) 1.09
TGFalpha expression impairs Trastuzumab-induced HER2 downregulation. Oncogene (2005) 1.03
A novel role for 14-3-3sigma in regulating epithelial cell polarity. Genes Dev (2010) 1.00
ARF1 controls proliferation of breast cancer cells by regulating the retinoblastoma protein. Oncogene (2011) 0.98
Rab coupling protein associates with phagosomes and regulates recycling from the phagosomal compartment. Traffic (2004) 0.98
Phosphorylation of Rab11-FIP2 regulates polarity in MDCK cells. Mol Biol Cell (2012) 0.98
Increased expression of Rab coupling protein in squamous cell carcinoma of the head and neck and its clinical significance. Oncol Lett (2012) 0.82