Published in Aging Cell on March 11, 2016
Inhibition of NAMPT aggravates high fat diet-induced hepatic steatosis in mice through regulating Sirt1/AMPKα/SREBP1 signaling pathway. Lipids Health Dis (2017) 0.86
NAD and the aging process: Role in life, death and everything in between. Mol Cell Endocrinol (2016) 0.85
Reductive carboxylation is a major metabolic pathway in the retinal pigment epithelium. Proc Natl Acad Sci U S A (2016) 0.77
Influence of anaerobic and aerobic exercise on age-related pathways in skeletal muscle. Ageing Res Rev (2017) 0.75
Practical alternatives to chronic caloric restriction for optimizing vascular function with ageing. J Physiol (2016) 0.75
The brain, sirtuins, and ageing. Nat Rev Neurosci (2017) 0.75
CVD and Oxidative Stress. J Clin Med (2017) 0.75
Nutrition and other lifestyle influences on arterial aging. Ageing Res Rev (2016) 0.75
NAD replenishment with nicotinamide mononucleotide protects blood-brain barrier integrity and attenuates delayed tPA-induced haemorrhagic transformation after cerebral ischemia. Br J Pharmacol (2017) 0.75
Modulating NAD(+) metabolism, from bench to bedside. EMBO J (2017) 0.75
Aortic Stiffness in Aging and Hypertension: Prevention and Treatment with Habitual Aerobic Exercise. Curr Hypertens Rep (2017) 0.75
Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells. Mol Metab (2017) 0.75
Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association. Circulation (2011) 14.00
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J (2004) 11.00
Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-analysis. J Am Coll Cardiol (2010) 9.44
Arterial stiffness and cardiovascular events: the Framingham Heart Study. Circulation (2010) 9.09
Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: Part I: aging arteries: a "set up" for vascular disease. Circulation (2003) 7.40
Elevated aortic pulse wave velocity, a marker of arterial stiffness, predicts cardiovascular events in well-functioning older adults. Circulation (2005) 6.89
The clinical implications of endothelial dysfunction. J Am Coll Cardiol (2003) 6.71
Endothelial function and dysfunction: testing and clinical relevance. Circulation (2007) 6.47
Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation (2001) 5.87
Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the Cardiovascular Health Study. Circulation (2007) 5.87
Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction. Cell (2010) 5.73
Mechanisms, pathophysiology, and therapy of arterial stiffness. Arterioscler Thromb Vasc Biol (2005) 5.39
Sirt1 protects against high-fat diet-induced metabolic damage. Proc Natl Acad Sci U S A (2008) 5.21
Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging. Cell (2013) 4.85
Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: a prospective study. Circulation (2002) 3.67
SirT1 regulates energy metabolism and response to caloric restriction in mice. PLoS One (2008) 3.66
Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function. Circ Res (2002) 3.51
Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab (2011) 3.38
The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity. Cell Metab (2012) 3.18
Aging and vascular endothelial function in humans. Clin Sci (Lond) (2011) 2.53
Age-associated loss of Sirt1-mediated enhancement of glucose-stimulated insulin secretion in beta cell-specific Sirt1-overexpressing (BESTO) mice. Aging Cell (2007) 2.18
Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1. Mech Ageing Dev (2009) 1.69
Physical and functional HAT/HDAC interplay regulates protein acetylation balance. J Biomed Biotechnol (2010) 1.55
Arterial stiffening with ageing is associated with transforming growth factor-β1-related changes in adventitial collagen: reversal by aerobic exercise. J Physiol (2010) 1.51
Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging. Aging Cell (2011) 1.49
Measurement of aortic input impedance in mice: effects of age on aortic stiffness. Am J Physiol Heart Circ Physiol (2003) 1.46
Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress. Aging Cell (2010) 1.41
Superoxide-lowering therapy with TEMPOL reverses arterial dysfunction with aging in mice. Aging Cell (2012) 1.29
FoxO1 mediates an autofeedback loop regulating SIRT1 expression. J Biol Chem (2010) 1.27
Vascular aging: chronic oxidative stress and impairment of redox signaling-consequences for vascular homeostasis and disease. Ann Med (2012) 1.18
The role of mammalian sirtuins in the regulation of metabolism, aging, and longevity. Handb Exp Pharmacol (2011) 1.16
SIRT-1 and vascular endothelial dysfunction with ageing in mice and humans. J Physiol (2011) 1.15
Arterial stiffness and extracellular matrix. Adv Cardiol (2007) 1.13
Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging. EMBO J (2014) 1.12
Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice. Aging Cell (2013) 1.11
Sodium nitrite de-stiffening of large elastic arteries with aging: role of normalization of advanced glycation end-products. Exp Gerontol (2012) 1.10
The sirtuins, oxidative stress and aging: an emerging link. Aging (Albany NY) (2013) 1.08
Arterial stiffness and hypertension. Hypertension (2014) 1.05
You're only as old as your arteries: translational strategies for preserving vascular endothelial function with aging. Physiology (Bethesda) (2014) 1.04
Characterizing the elastic properties of tissues. Mater Today (Kidlington) (2011) 1.03
Curcumin ameliorates arterial dysfunction and oxidative stress with aging. Exp Gerontol (2012) 0.98
A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis. Pharmacol Res (2010) 0.98
The autophagy enhancer spermidine reverses arterial aging. Mech Ageing Dev (2013) 0.95
Overview of pyridine nucleotides review series. Circ Res (2012) 0.92
The SIRT1 activator SRT1720 reverses vascular endothelial dysfunction, excessive superoxide production, and inflammation with aging in mice. Am J Physiol Heart Circ Physiol (2014) 0.91
The mitochondrial permeability transition pore regulates endothelial bioenergetics and angiogenesis. Circ Res (2015) 0.81
The effect of caloric restriction on the aortic tissue of aging rats. Connect Tissue Res (1999) 0.78
Niacin receptor activation improves human microvascular endothelial cell angiogenic function during lipotoxicity. Atherosclerosis (2014) 0.77
A seat at the table. Genome Biol (2008) 0.77