Published in Oncotarget on April 19, 2016
miR-449a inhibits proliferation and invasion by regulating ADAM10 in hepatocellular carcinoma. Am J Transl Res (2016) 0.75
MicroRNA expression profiles classify human cancers. Nature (2005) 69.12
A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A (2006) 40.09
MicroRNA gene expression deregulation in human breast cancer. Cancer Res (2005) 27.56
MicroRNA biogenesis: coordinated cropping and dicing. Nat Rev Mol Cell Biol (2005) 18.94
Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell (2005) 15.26
Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer (2003) 13.01
MicroRNA signatures in human ovarian cancer. Cancer Res (2007) 9.45
MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc Natl Acad Sci U S A (2003) 8.73
Mammalian sirtuins--emerging roles in physiology, aging, and calorie restriction. Genes Dev (2006) 8.48
An integrated network of androgen receptor, polycomb, and TMPRSS2-ERG gene fusions in prostate cancer progression. Cancer Cell (2010) 6.76
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype. Genome Biol (2007) 6.41
Processing of intronic microRNAs. EMBO J (2007) 6.32
Role of the TMPRSS2-ERG gene fusion in prostate cancer. Neoplasia (2008) 5.92
MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer (2006) 5.37
Sirtuins in aging and age-related disease. Cell (2006) 3.95
Small RNAs: classification, biogenesis, and function. Mol Cells (2005) 3.59
Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. Mol Cell Biol (2006) 3.37
How does SIRT1 affect metabolism, senescence and cancer? Nat Rev Cancer (2008) 3.17
Frequent overexpression of ETS-related gene-1 (ERG1) in prostate cancer transcriptome. Oncogene (2005) 3.13
SIRT1 is significantly elevated in mouse and human prostate cancer. Cancer Res (2007) 2.98
TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation. Oncogene (2008) 2.94
SIRT1, is it a tumor promoter or tumor suppressor? Int J Biol Sci (2009) 2.80
miR-449a targets HDAC-1 and induces growth arrest in prostate cancer. Oncogene (2009) 2.61
The critical role of the class III histone deacetylase SIRT1 in cancer. Cancer Res (2009) 2.29
ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss. Nat Med (2013) 2.26
Hormonal control of androgen receptor function through SIRT1. Mol Cell Biol (2006) 1.91
miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A. Genes Dev (2009) 1.91
Dysregulation of microRNAs in cancer: playing with fire. FEBS Lett (2010) 1.79
MicroRNA-449a acts as a tumor suppressor in human bladder cancer through the regulation of pocket proteins. Cancer Lett (2012) 1.73
SIRT1 induces EMT by cooperating with EMT transcription factors and enhances prostate cancer cell migration and metastasis. Oncogene (2012) 1.70
E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis. Cell Death Differ (2009) 1.66
Comprehensive microRNA Profiling of Prostate Cancer. J Cancer (2013) 1.53
TMPRSS2-ERG gene fusions induce prostate tumorigenesis by modulating microRNA miR-200c. Oncogene (2013) 1.51
miR-449 inhibits cell proliferation and is down-regulated in gastric cancer. Mol Cancer (2011) 1.46
Role of sirtuin histone deacetylase SIRT1 in prostate cancer. A target for prostate cancer management via its inhibition? J Biol Chem (2008) 1.46
Tumour suppressive microRNA-874 regulates novel cancer networks in maxillary sinus squamous cell carcinoma. Br J Cancer (2011) 1.45
Delineation of TMPRSS2-ERG splice variants in prostate cancer. Clin Cancer Res (2008) 1.35
miR-30 as a tumor suppressor connects EGF/Src signal to ERG and EMT. Oncogene (2013) 1.24
The epidermal growth factor receptor responsive miR-125a represses mesenchymal morphology in ovarian cancer cells. Neoplasia (2009) 1.20
Clinical potential of the ERG oncoprotein in prostate cancer. Nat Rev Urol (2012) 1.17
Oncogenic activation of ERG: A predominant mechanism in prostate cancer. J Carcinog (2011) 1.13
The proto-oncogene ERG is a target of microRNA miR-145 in prostate cancer. FEBS J (2013) 1.13
SIRT1 modulates aggregation and toxicity through deacetylation of the androgen receptor in cell models of SBMA. J Neurosci (2011) 1.05
miR-221 Is down-regulated in TMPRSS2:ERG fusion-positive prostate cancer. Anticancer Res (2011) 0.99
MicroRNA-520g induces epithelial-mesenchymal transition and promotes metastasis of hepatocellular carcinoma by targeting SMAD7. FEBS Lett (2014) 0.96
Identification of novel TMPRSS2:ERG mechanisms in prostate cancer metastasis: involvement of MMP9 and PLXNA2. Oncogene (2013) 0.95
SPOP mutation leads to genomic instability in prostate cancer. Elife (2015) 0.93
Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma. BMC Cancer (2014) 0.92
MiR-449a functions as a tumor suppressor in endometrial cancer by targeting CDC25A. Oncol Rep (2014) 0.88
SIRT1 is a regulator of autophagy: Implications in gastric cancer progression and treatment. FEBS Lett (2015) 0.87
MiR-449a suppresses the epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma by multiple targets. BMC Cancer (2015) 0.87
microRNA-449a functions as a tumor-suppressor in gastric adenocarcinoma by targeting Bcl-2. Oncol Lett (2013) 0.85
MicroRNAs-449a and -449b exhibit tumor suppressive effects in retinoblastoma. Biochem Biophys Res Commun (2013) 0.84
Landscape of gene fusions in epithelial cancers: seq and ye shall find. Genome Med (2015) 0.84
Methylation of the PMEPA1 gene, a negative regulator of the androgen receptor in prostate cancer. Epigenetics (2014) 0.83
SIRT1 suppresses breast cancer growth through downregulation of the Bcl-2 protein. Oncol Rep (2013) 0.81
microRNA-449a functions as a tumor suppressor in neuroblastoma through inducing cell differentiation and cell cycle arrest. RNA Biol (2015) 0.80
Effect of SIRT1 Gene on Epithelial-Mesenchymal Transition of Human Prostate Cancer PC-3 Cells. Med Sci Monit (2016) 0.77