Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level.

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Published in Elife on March 14, 2016

Authors

Daniel Coutandin1,2,3, Christian Osterburg1,2,3, Ratnesh Kumar Srivastav1,2,3, Manuela Sumyk1,2,3, Sebastian Kehrloesser1,2,3, Jakob Gebel1,2,3, Marcel Tuppi1,2,3, Jens Hannewald4, Birgit Schäfer1,2,3, Eidarus Salah5, Sebastian Mathea5, Uta Müller-Kuller6, James Doutch7, Manuel Grez6, Stefan Knapp5,8,9, Volker Dötsch1,2,3

Author Affiliations

1: Institute of Biophysical Chemistry, Goethe University, Frankfurt, Germany.
2: Center for Biomolecular Magnetic Resonance, Goethe University, Frankfurt, Germany.
3: Cluster of Excellence Macromolecular Complexes, Goethe University, Frankfurt, Germany.
4: MS-DTB-C Protein Purification, Merck KGaA, Darmstadt, Germany.
5: Nuffield Department of Medicine, Structural Genomics Consortium, University of Oxford, Oxford, United Kingdom.
6: Georg-Speyer Haus, Frankfurt, Germany.
7: ISIS Neutron and Muon Source, Rutherford Appleton Laboratory, Didcot, United Kingdom.
8: Institute for Pharmaceutical Chemistry, Goethe University, Frankfurt, Germany.
9: Buchmann Institute for Molecular Life Science, Goethe University, Frankfurt, Germany.

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