Published in Nucleic Acids Res on April 15, 2016
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XAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE. Cell Death Dis (2016) 0.76
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A phosphorylation-and-ubiquitylation circuitry driving ATR activation and homologous recombination. Nucleic Acids Res (2017) 0.75
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Human CtIP promotes DNA end resection. Nature (2007) 10.63
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53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell (2010) 8.70
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53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. Nat Struct Mol Biol (2010) 5.59
DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains. Mol Cell Biol (2004) 4.78
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A genome-wide siRNA screen reveals diverse cellular processes and pathways that mediate genome stability. Mol Cell (2009) 4.17
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Genetic steps of mammalian homologous repair with distinct mutagenic consequences. Mol Cell Biol (2004) 3.96
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BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP. Genes Dev (2006) 3.44
Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining. Nat Struct Mol Biol (2010) 3.27
Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination. Nat Struct Mol Biol (2013) 3.18
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A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. Nat Cell Biol (2012) 2.51
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Collaboration and competition between DNA double-strand break repair pathways. FEBS Lett (2010) 2.11
Dynamic protein-protein interaction wiring of the human spliceosome. Mol Cell (2012) 2.04
PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry. Mol Cell (2013) 1.95
Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks. Nat Struct Mol Biol (2014) 1.89
Sequential posttranslational modifications program FEN1 degradation during cell-cycle progression. Mol Cell (2012) 1.76
A high-throughput RNA interference screen for DNA repair determinants of PARP inhibitor sensitivity. DNA Repair (Amst) (2008) 1.70
Extensive loss of heterozygosity is suppressed during homologous repair of chromosomal breaks. Mol Cell Biol (2003) 1.65
I-SceI-based assays to examine distinct repair outcomes of mammalian chromosomal double strand breaks. Methods Mol Biol (2012) 1.59
Structural and functional discussion of the tetra-trico-peptide repeat, a protein interaction module. Structure (2012) 1.57
BRCA1 promotes induction of ssDNA by ionizing radiation. Cancer Res (2006) 1.55
Regulation of DNA-end resection by hnRNPU-like proteins promotes DNA double-strand break signaling and repair. Mol Cell (2012) 1.50
The Prp19 U-box crystal structure suggests a common dimeric architecture for a class of oligomeric E3 ubiquitin ligases. Biochemistry (2006) 1.38
Isolation of XAB2 complex involved in pre-mRNA splicing, transcription, and transcription-coupled repair. J Biol Chem (2007) 1.32
Push back to respond better: regulatory inhibition of the DNA double-strand break response. Nat Rev Mol Cell Biol (2013) 1.29
The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair. PLoS Genet (2013) 1.27
Correct end use during end joining of multiple chromosomal double strand breaks is influenced by repair protein RAD50, DNA-dependent protein kinase DNA-PKcs, and transcription context. J Biol Chem (2011) 1.23
XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription. J Biol Chem (2000) 1.18
Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair. J Cell Biol (2011) 1.16
BRCA1 accelerates CtIP-mediated DNA-end resection. Cell Rep (2014) 1.15
Controlling DNA-end resection: a new task for CDKs. Front Genet (2013) 1.09
PSO4: a novel gene involved in error-prone repair in Saccharomyces cerevisiae. Mutat Res (1989) 1.04
DNA damage response factors from diverse pathways, including DNA crosslink repair, mediate alternative end joining. PLoS Genet (2015) 1.02
The interaction between CtIP and BRCA1 is not essential for resection-mediated DNA repair or tumor suppression. J Cell Biol (2013) 1.00
A high-throughput, flow cytometry-based method to quantify DNA-end resection in mammalian cells. Cytometry A (2012) 1.00
Opposing roles for 53BP1 during homologous recombination. Nucleic Acids Res (2013) 0.99
BRCA1 and CtIP suppress long-tract gene conversion between sister chromatids. Nat Commun (2013) 0.96
CtIP-mediated resection is essential for viability and can operate independently of BRCA1. J Exp Med (2014) 0.94
The Pso4 complex splices into the DNA damage response. Cell Cycle (2009) 0.94
The PSO4 protein complex associates with replication protein A (RPA) and modulates the activation of ataxia telangiectasia-mutated and Rad3-related (ATR). J Biol Chem (2014) 0.93
Pre-mRNA processing factors meet the DNA damage response. Front Genet (2013) 0.92
RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1. J Biol Chem (2012) 0.90
A Synthetic Lethal Screen Identifies DNA Repair Pathways that Sensitize Cancer Cells to Combined ATR Inhibition and Cisplatin Treatments. PLoS One (2015) 0.89
Requirement for highly efficient pre-mRNA splicing during Drosophila early embryonic development. Elife (2014) 0.87
Disruption of mouse XAB2 gene involved in pre-mRNA splicing, transcription and transcription-coupled DNA repair results in preimplantation lethality. DNA Repair (Amst) (2005) 0.87
The role of the human psoralen 4 (hPso4) protein complex in replication stress and homologous recombination. J Biol Chem (2014) 0.82
hPso4/hPrp19: a critical component of DNA repair and DNA damage checkpoint complexes. Oncogene (2015) 0.79
The NineTeen Complex (NTC) and NTC-associated proteins as targets for spliceosomal ATPase action during pre-mRNA splicing. RNA Biol (2015) 0.77
Emerging role of protein phosphatases changes the landscape of phospho-signaling in DNA damage response. DNA Repair (Amst) (2015) 0.76