Published in Acta Naturae on April 21, 2016
Cholesterol in the Pathogenesis of Alzheimer's, Parkinson's Diseases and Autism: Link to Synaptic Dysfunction. Acta Naturae (2017) 0.75
Changes in brain oxysterols at different stages of Alzheimer's disease: Their involvement in neuroinflammation. Redox Biol (2016) 0.75
Endoplasmic Reticulum Malfunction in the Nervous System. Front Neurosci (2017) 0.75
Membrane lipid rafts disturbance in the response of rat skeletal muscle to short-term disuse. Am J Physiol Cell Physiol (2017) 0.75
Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy. Nat Rev Neurosci (2009) 3.97
Reversal of defective lysosomal transport in NPC disease ameliorates liver dysfunction and neurodegeneration in the npc1-/- mouse. Proc Natl Acad Sci U S A (2009) 2.88
Lipid rafts in the maintenance of synapses, dendritic spines, and surface AMPA receptor stability. J Neurosci (2003) 2.80
Expression of apolipoprotein E during nerve degeneration and regeneration. Proc Natl Acad Sci U S A (1986) 2.80
Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice. EMBO J (2007) 2.39
High cholesterol level is essential for myelin membrane growth. Nat Neurosci (2005) 2.34
ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL. J Lipid Res (2006) 2.15
The SNARE motif is essential for the formation of syntaxin clusters in the plasma membrane. Biophys J (2006) 2.04
BDNF function and intracellular signaling in neurons. Histol Histopathol (2010) 1.99
Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain. Annu Rev Biochem (2009) 1.61
Biochemical, phenotypic and neurophysiological characterization of a genetic mouse model of RSH/Smith--Lemli--Opitz syndrome. Hum Mol Genet (2001) 1.60
Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease. J Lipid Res (2003) 1.50
Pericyte loss influences Alzheimer-like neurodegeneration in mice. Nat Commun (2013) 1.45
Biological activities of 7-dehydrocholesterol-derived oxysterols: implications for Smith-Lemli-Opitz syndrome. J Lipid Res (2010) 1.44
Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth. Proc Natl Acad Sci U S A (2005) 1.44
Oxysterols: Sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis. Mol Aspects Med (2009) 1.42
Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration. J Neurosci (2010) 1.38
Association of excitatory amino acid transporters, especially EAAT2, with cholesterol-rich lipid raft microdomains: importance for excitatory amino acid transporter localization and function. J Biol Chem (2004) 1.32
Dysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseases. Dis Model Mech (2012) 1.31
A scissors mechanism for stimulation of SNARE-mediated lipid mixing by cholesterol. Proc Natl Acad Sci U S A (2009) 1.28
Central nervous system: cholesterol turnover, brain development and neurodegeneration. Biol Chem (2009) 1.25
ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD. Proc Natl Acad Sci U S A (2010) 1.23
Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease. Mol Ther (2009) 1.23
Lipid regulation of the synaptic vesicle cycle. Nat Rev Neurosci (2005) 1.22
Normalization of cholesterol homeostasis by 2-hydroxypropyl-β-cyclodextrin in neurons and glia from Niemann-Pick C1 (NPC1)-deficient mice. J Biol Chem (2012) 1.22
Cholesterol and synaptic transmitter release at crayfish neuromuscular junctions. J Physiol (2005) 1.17
Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes. J Neurosci (2010) 1.15
Smith-Lemli-Opitz syndrome: phenotype, natural history, and epidemiology. Am J Med Genet C Semin Med Genet (2012) 1.09
Accumulation and aggregation of amyloid beta-protein in late endosomes of Niemann-pick type C cells. J Biol Chem (2000) 1.09
Peroxisome-proliferator-activated receptor gamma coactivator 1 α contributes to dysmyelination in experimental models of Huntington's disease. J Neurosci (2011) 1.09
Regulation of AMPA receptor localization in lipid rafts. Mol Cell Neurosci (2008) 1.07
The major brain cholesterol metabolite 24(S)-hydroxycholesterol is a potent allosteric modulator of N-methyl-D-aspartate receptors. J Neurosci (2013) 1.06
SCAP is required for timely and proper myelin membrane synthesis. Proc Natl Acad Sci U S A (2009) 1.05
Activation of Rho GTPases in Smith-Lemli-Opitz syndrome: pathophysiological and clinical implications. Hum Mol Genet (2010) 1.05
More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration. Neuron (2014) 1.04
Prion protein-mediated toxicity of amyloid-β oligomers requires lipid rafts and the transmembrane LRP1. J Biol Chem (2013) 1.01
PGC-1α at the intersection of bioenergetics regulation and neuron function: from Huntington's disease to Parkinson's disease and beyond. Prog Neurobiol (2011) 1.00
Differential effects of cholesterol and 7-dehydrocholesterol on the ligand binding activity of the hippocampal serotonin(1A) receptor: implications in SLOS. Biochem Biophys Res Commun (2007) 0.99
Loss of SNAP-25 and rabphilin 3a in sensory-motor cortex in Huntington's disease. J Neurochem (2007) 0.97
Niemann-Pick C disease and mobilization of lysosomal cholesterol by cyclodextrin. J Lipid Res (2014) 0.96
Oxysterols in the circulation of patients with the Smith-Lemli-Opitz syndrome: abnormal levels of 24S- and 27-hydroxycholesterol. J Lipid Res (2001) 0.95
Apolipoprotein E is resistant to intracellular degradation in vitro and in vivo. Evidence for retroendocytosis. J Biol Chem (2000) 0.95
Quantitative proteomics analysis of detergent-resistant membranes from chemical synapses: evidence for cholesterol as spatial organizer of synaptic vesicle cycling. Mol Cell Proteomics (2006) 0.95
Blood-brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment. Immun Ageing (2015) 0.95
Effects of a disrupted blood-brain barrier on cholesterol homeostasis in the brain. J Biol Chem (2014) 0.94
Increased non-quantal release of acetylcholine after inhibition of endocytosis by methyl-β-cyclodextrin: the role of vesicular acetylcholine transporter. Neuroscience (2011) 0.94
Cellular stress from excitatory neurotransmission contributes to cholesterol loss in hippocampal neurons aging in vitro. Neurobiol Aging (2010) 0.93
Cholesterol modulates open probability and desensitization of NMDA receptors. J Physiol (2015) 0.91
Cholesterol loss during glutamate-mediated excitotoxicity. EMBO J (2012) 0.91
The Niemann-Pick C1 protein in recycling endosomes of presynaptic nerve terminals. J Lipid Res (2005) 0.90
ABCA1 influences neuroinflammation and neuronal death. Neurobiol Dis (2013) 0.90
Lipid metabolism and glial lipoproteins in the central nervous system. Biol Pharm Bull (2011) 0.89
Caveolins: targeting pro-survival signaling in the heart and brain. Front Physiol (2012) 0.89
Association of membrane rafts and postsynaptic density: proteomics, biochemical, and ultrastructural analyses. J Neurochem (2011) 0.88
Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents. EMBO Mol Med (2014) 0.87
Rab11 rescues synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington's disease. Hum Mol Genet (2012) 0.87
Bidirectional links between Alzheimer's disease and Niemann-Pick type C disease. Neurobiol Dis (2014) 0.87
Mitochondrial membrane fluidity is consistently increased in different models of Huntington disease: restorative effects of olesoxime. Mol Neurobiol (2014) 0.87
Localization of synaptic proteins involved in neurosecretion in different membrane microdomains. J Neurochem (2006) 0.86
Cholesterol-dependent kinase activity regulates transmitter release from cerebellar synapses. J Neurosci (2010) 0.85
Metabolic and hormonal signatures in pre-manifest and manifest Huntington's disease patients. Front Physiol (2014) 0.84
The driving force of alpha-synuclein insertion and amyloid channel formation in the plasma membrane of neural cells: key role of ganglioside- and cholesterol-binding domains. Adv Exp Med Biol (2013) 0.84
Decreased cerebral spinal fluid neurotransmitter levels in Smith-Lemli-Opitz syndrome. J Inherit Metab Dis (2014) 0.84
β-Cyclodextrin-threaded biocleavable polyrotaxanes ameliorate impaired autophagic flux in Niemann-Pick type C disease. J Biol Chem (2015) 0.84
Calcium signaling and neurodegeneration. Acta Naturae (2010) 0.83
High-fat diet ameliorates neurological deficits caused by defective astrocyte lipid metabolism. FASEB J (2012) 0.83
Defects of synaptic vesicle turnover at excitatory and inhibitory synapses in Niemann-Pick C1-deficient neurons. Neuroscience (2010) 0.83
Comparison of the liquid-ordered bilayer phases containing cholesterol or 7-dehydrocholesterol in modeling Smith-Lemli-Opitz syndrome. J Lipid Res (2010) 0.82
Pre-synaptic defects of NPC1-deficient hippocampal neurons are not directly related to plasma membrane cholesterol. J Neurochem (2010) 0.82
Cholesterol depletion from the plasma membrane impairs proton and glutamate storage in synaptic vesicles of nerve terminals. J Mol Neurosci (2010) 0.82
Formation of Toxic Amyloid Fibrils by Amyloid β-Protein on Ganglioside Clusters. Int J Alzheimers Dis (2011) 0.82
Loss of caveolin-1 expression in knock-in mouse model of Huntington's disease suppresses pathophysiology in vivo. Hum Mol Genet (2013) 0.82
LTP-triggered cholesterol redistribution activates Cdc42 and drives AMPA receptor synaptic delivery. J Cell Biol (2015) 0.82
Effects of oxysterols on the blood-brain barrier: implications for Alzheimer's disease. Biochem Biophys Res Commun (2013) 0.81
Pharmacological protein targets in polyglutamine diseases: mutant polypeptides and their interactors. FEBS Lett (2013) 0.80
Role of membrane cholesterol in spontaneous exocytosis at frog neuromuscular synapses: reactive oxygen species-calcium interplay. J Physiol (2014) 0.80
Apolipoprotein E genotype and neurological disease onset in Niemann-Pick disease, type C1. Am J Med Genet A (2012) 0.79
The role of cholesterol in the exo- and endocytosis of synaptic vesicles in frog motor nerve endings. Neurosci Behav Physiol (2010) 0.79
Protein Misfolding in Lipid-Mimetic Environments. Adv Exp Med Biol (2015) 0.78
Effects of 5α-cholestan-3-one on the synaptic vesicle cycle at the mouse neuromuscular junction. Biochim Biophys Acta (2015) 0.77
[Cholesterol and lipid rafts in the biological membranes. Role in the release, reception and ion channel functions]. Usp Fiziol Nauk (2013) 0.76
The role of membrane cholesterol in neurotransmitter release from motor nerve terminals. Dokl Biol Sci (2011) 0.76
Inhibition of protein kinase C affects on mode of synaptic vesicle exocytosis due to cholesterol depletion. Biochem Biophys Res Commun (2014) 0.76