Published in Infect Immun on January 12, 2009
A critical role for hemolysins and bacterial lipoproteins in Staphylococcus aureus-induced activation of the Nlrp3 inflammasome. J Immunol (2009) 2.29
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Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses. PLoS Pathog (2010) 1.17
Staphylococcus aureus induces type I IFN signaling in dendritic cells via TLR9. J Immunol (2012) 1.16
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A genome-wide siRNA screen reveals positive and negative regulators of the NOD2 and NF-κB signaling pathways. Sci Signal (2013) 0.99
Chronic morphine administration delays wound healing by inhibiting immune cell recruitment to the wound site. Am J Pathol (2009) 0.99
The rise and rise of Staphylococcus aureus: laughing in the face of granulocytes. Clin Exp Immunol (2009) 0.98
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Bonds between fibronectin and fibronectin-binding proteins on Staphylococcus aureus and Lactococcus lactis. Langmuir (2010) 0.91
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Pivotal role of NOD2 in inflammatory processes affecting atherosclerosis and periodontal bone loss. Proc Natl Acad Sci U S A (2013) 0.88
Role of macrophages in the pathogenesis of atopic dermatitis. Mediators Inflamm (2013) 0.88
Retracted NOD2 signaling contributes to host defense in the lungs against Escherichia coli infection. Infect Immun (2012) 0.87
Recognition of Extracellular Bacteria by NLRs and Its Role in the Development of Adaptive Immunity. Front Immunol (2013) 0.87
Olfm4 deletion enhances defense against Staphylococcus aureus in chronic granulomatous disease. J Clin Invest (2013) 0.86
Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replication. PLoS One (2014) 0.85
Haplotype Association Mapping Identifies a Candidate Gene Region in Mice Infected With Staphylococcus aureus. G3 (Bethesda) (2012) 0.83
Bacterial interference with canonical NFκB signalling. Microbiology (2013) 0.83
Methicillin-resistant Staphylococcus aureus adaptation to human keratinocytes. MBio (2015) 0.82
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Powerful Complex Immunoadjuvant Based on Synergistic Effect of Combined TLR4 and NOD2 Activation Significantly Enhances Magnitude of Humoral and Cellular Adaptive Immune Responses. PLoS One (2016) 0.80
A genome-wide small interfering RNA (siRNA) screen reveals nuclear factor-κB (NF-κB)-independent regulators of NOD2-induced interleukin-8 (IL-8) secretion. J Biol Chem (2014) 0.79
Significance of mannose-binding lectin deficiency and nucleotide-binding oligomerization domain 2 polymorphisms in Staphylococcus aureus bloodstream infections: a case-control study. PLoS One (2013) 0.79
Modulation of the local neutrophil response by a novel hyaluronic acid-binding peptide reduces bacterial burden during staphylococcal wound infection. Infect Immun (2010) 0.78
Current knowledge and future directions of TLR and NOD signaling in sepsis. Mil Med Res (2015) 0.77
Bacterial Muramyl Dipeptide (MDP) Restricts Human Cytomegalovirus Replication via an IFN-β-Dependent Pathway. Sci Rep (2016) 0.76
The Janus face of α-toxin: a potent mediator of cytoprotection in staphylococci-infected macrophages. J Innate Immun (2014) 0.76
Implication of TLR- but not of NOD2-signaling pathways in dendritic cell activation by group B Streptococcus serotypes III and V. PLoS One (2014) 0.76
Concurrent exposure to microbial products and food antigens triggers initiation of food allergy. N Am J Med Sci (2009) 0.75
Nod2: A Critical Regulator of Ileal Microbiota and Crohn's Disease. Front Immunol (2016) 0.75
Role of Nucleotide-Binding Oligomerization Domain-Containing (NOD) 2 in Host Defense during Pneumococcal Pneumonia. PLoS One (2015) 0.75
Heme Oxygenase-1 Deficiency Diminishes Methicillin-Resistant Staphylococcus aureus Clearance Due to Reduced TLR9 Expression in Pleural Mesothelial Cells. PLoS One (2017) 0.75
Role of Nucleotide-binding and Oligomerization Domain 2 Protein (NOD2) in the Development of Atherosclerosis. Korean J Physiol Pharmacol (2015) 0.75
Toll-like receptor 9 enhances bacterial clearance and limits lung consolidation in murine pneumonia caused by methicillin resistant Staphylococcus aureus. Mol Med (2016) 0.75
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A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide. Proc Natl Acad Sci U S A (2008) 3.27
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NOD2 transgenic mice exhibit enhanced MDP-mediated down-regulation of TLR2 responses and resistance to colitis induction. Gastroenterology (2007) 2.03
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Role for erbin in bacterial activation of Nod2. Infect Immun (2006) 1.63
Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus. J Neurochem (2004) 1.56
The origin of the synergistic effect of muramyl dipeptide with endotoxin and peptidoglycan. J Biol Chem (2002) 1.53
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Modulation of Nod2-dependent NF-kappaB signaling by the actin cytoskeleton. J Cell Sci (2007) 1.29
Innate immune sensing of microbes by Nod proteins. Ann N Y Acad Sci (2006) 1.24
Common nonsynonymous polymorphisms in the NOD2 gene are associated with resistance or susceptibility to tuberculosis disease in African Americans. J Infect Dis (2008) 1.23
The TLR2-MyD88-NOD2-RIPK2 signalling axis regulates a balanced pro-inflammatory and IL-10-mediated anti-inflammatory cytokine response to Gram-positive cell walls. Cell Microbiol (2008) 1.23
Differential contribution of Toll-like receptors 4 and 2 to the cytokine response to Salmonella enterica serovar Typhimurium and Staphylococcus aureus in mice. Infect Immun (2003) 1.22
Toll-like receptor 2 mediates Staphylococcus aureus-induced myocardial dysfunction and cytokine production in the heart. Circulation (2004) 1.19
Contribution of phagocytosis and intracellular sensing for cytokine production by Staphylococcus aureus-activated macrophages. Infect Immun (2006) 1.19
NOD2 regulation of Toll-like receptor responses and the pathogenesis of Crohn's disease. Gut (2005) 1.17
Bacterial and host factors implicated in nasal carriage of methicillin-resistant Staphylococcus aureus in mice. Infect Immun (2005) 1.10
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Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study. Arch Intern Med (2009) 7.82
Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgical site infection. Clin Infect Dis (2003) 4.06
In-hospital and 1-year mortality in patients undergoing early surgery for prosthetic valve endocarditis. JAMA Intern Med (2013) 3.72
Use of vancomycin or first-generation cephalosporins for the treatment of hemodialysis-dependent patients with methicillin-susceptible Staphylococcus aureus bacteremia. Clin Infect Dis (2006) 3.70
Histone H3 lysine 4 demethylation is a target of nonselective antidepressive medications. Chem Biol (2006) 3.15
Contemporary clinical profile and outcome of prosthetic valve endocarditis. JAMA (2007) 3.03
Clinical characteristics and outcome of infective endocarditis involving implantable cardiac devices. JAMA (2012) 3.01
Aorto-cavitary fistulous tract formation in infective endocarditis: clinical and echocardiographic features of 76 cases and risk factors for mortality. Eur Heart J (2004) 2.85
Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association. Circulation (2015) 2.84
Telavancin versus vancomycin for the treatment of complicated skin and skin-structure infections caused by gram-positive organisms. Clin Infect Dis (2008) 2.73
Changing patient characteristics and the effect on mortality in endocarditis. Arch Intern Med (2002) 2.68
Use of a simple criteria set for guiding echocardiography in nosocomial Staphylococcus aureus bacteremia. Clin Infect Dis (2011) 2.62
Reassessing the role of the secreted protease CPAF in Chlamydia trachomatis infection through genetic approaches. Pathog Dis (2014) 2.50
Is it time to replace vancomycin in the treatment of methicillin-resistant Staphylococcus aureus infections? Clin Infect Dis (2013) 2.44
Staphylococcus aureus native valve infective endocarditis: report of 566 episodes from the International Collaboration on Endocarditis Merged Database. Clin Infect Dis (2005) 2.36
Reduced susceptibility of Staphylococcus aureus to vancomycin and platelet microbicidal protein correlates with defective autolysis and loss of accessory gene regulator (agr) function. Antimicrob Agents Chemother (2005) 2.34
Early predictors of in-hospital death in infective endocarditis. Circulation (2004) 2.26
An integrated clinico-metabolomic model improves prediction of death in sepsis. Sci Transl Med (2013) 2.23
Analysis of the impact of early surgery on in-hospital mortality of native valve endocarditis: use of propensity score and instrumental variable methods to adjust for treatment-selection bias. Circulation (2010) 2.01
Neonatal meningitis: what is the correlation among cerebrospinal fluid cultures, blood cultures, and cerebrospinal fluid parameters? Pediatrics (2006) 1.98
trans-2-Phenylcyclopropylamine is a mechanism-based inactivator of the histone demethylase LSD1. Biochemistry (2007) 1.97
Telavancin versus standard therapy for treatment of complicated skin and soft-tissue infections due to gram-positive bacteria. Clin Infect Dis (2005) 1.95
Genotypic characteristics of Staphylococcus aureus isolates from a multinational trial of complicated skin and skin structure infections. J Clin Microbiol (2007) 1.91
Increasing rates of cardiac device infections among Medicare beneficiaries: 1990-1999. Am Heart J (2004) 1.90
Telavancin versus standard therapy for treatment of complicated skin and skin structure infections caused by gram-positive bacteria: FAST 2 study. Antimicrob Agents Chemother (2006) 1.84
Initial low-dose gentamicin for Staphylococcus aureus bacteremia and endocarditis is nephrotoxic. Clin Infect Dis (2009) 1.80
Native valve endocarditis due to coagulase-negative staphylococci: report of 99 episodes from the International Collaboration on Endocarditis Merged Database. Clin Infect Dis (2004) 1.80
Early surgery in patients with infective endocarditis: a propensity score analysis. Clin Infect Dis (2007) 1.78
Health care-associated native valve endocarditis: importance of non-nosocomial acquisition. Ann Intern Med (2009) 1.76
Endocarditis caused by Staphylococcus aureus with reduced susceptibility to vancomycin. Clin Infect Dis (2004) 1.73
Prevalence of infective endocarditis in patients with Staphylococcus aureus bacteraemia: the value of screening with echocardiography. Eur J Echocardiogr (2011) 1.72
Venous thrombosis in patients with short- and long-term central venous catheter-associated Staphylococcus aureus bacteremia. Crit Care Med (2008) 1.69
Costs and outcomes among hemodialysis-dependent patients with methicillin-resistant or methicillin-susceptible Staphylococcus aureus bacteremia. Infect Control Hosp Epidemiol (2005) 1.69
Rising rates of carbapenem-resistant enterobacteriaceae in community hospitals: a mixed-methods review of epidemiology and microbiology practices in a network of community hospitals in the southeastern United States. Infect Control Hosp Epidemiol (2014) 1.67
Presence of genes encoding the panton-valentine leukocidin exotoxin is not the primary determinant of outcome in patients with complicated skin and skin structure infections due to methicillin-resistant Staphylococcus aureus: results of a multinational trial. J Clin Microbiol (2009) 1.64
Multiplex PCR to diagnose bloodstream infections in patients admitted from the emergency department with sepsis. J Clin Microbiol (2009) 1.63
Surgical treatment of pacemaker and defibrillator lead endocarditis: the impact of electrode lead extraction on outcome. Chest (2003) 1.62
Methicillin-susceptible Staphylococcus aureus endocarditis isolates are associated with clonal complex 30 genotype and a distinct repertoire of enterotoxins and adhesins. J Infect Dis (2011) 1.59
Identifying and aligning expectations in a mentoring relationship. Clin Transl Sci (2011) 1.58
Non-HACEK gram-negative bacillus endocarditis. Ann Intern Med (2007) 1.56
Disease progression in hemodynamically stable patients presenting to the emergency department with sepsis. Acad Emerg Med (2010) 1.54
No survival benefit with empirical vancomycin therapy for coagulase-negative staphylococcal bloodstream infections in infants. Pediatr Infect Dis J (2015) 1.53
Crystal structure of Streptococcus pyogenes sortase A: implications for sortase mechanism. J Biol Chem (2009) 1.52
Reduced valve replacement surgery and complication rate in Staphylococcus aureus endocarditis patients receiving acetyl-salicylic acid. J Infect (2009) 1.51
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Vancomycin minimum inhibitory concentration and outcome in patients with Staphylococcus aureus bacteremia: pearl or pellet? J Infect Dis (2011) 1.41
Clinical outcomes and costs due to Staphylococcus aureus bacteremia among patients receiving long-term hemodialysis. Infect Control Hosp Epidemiol (2005) 1.38
Phenotypic and genotypic characteristics of persistent methicillin-resistant Staphylococcus aureus bacteremia in vitro and in an experimental endocarditis model. J Infect Dis (2009) 1.37
Emergence of coagulase-negative staphylococci as a cause of native valve endocarditis. Clin Infect Dis (2008) 1.37
Associations between the genotypes of Staphylococcus aureus bloodstream isolates and clinical characteristics and outcomes of bacteremic patients. J Clin Microbiol (2008) 1.36
Clinical characteristics and outcome of aortic endocarditis with periannular abscess in the International Collaboration on Endocarditis Merged Database. Am J Cardiol (2005) 1.36
Inoculum effect with cefazolin among clinical isolates of methicillin-susceptible Staphylococcus aureus: frequency and possible cause of cefazolin treatment failure. Antimicrob Agents Chemother (2009) 1.35
Analysis of the substrate specificity of the Staphylococcus aureus sortase transpeptidase SrtA. Biochemistry (2004) 1.34
Staphylococcus aureus bacteraemia in a tropical setting: patient outcome and impact of antibiotic resistance. PLoS One (2009) 1.32
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Sortase transpeptidases: insights into mechanism, substrate specificity, and inhibition. Biopolymers (2010) 1.26
The relationship between the initiation of antimicrobial therapy and the incidence of stroke in infective endocarditis: an analysis from the ICE Prospective Cohort Study (ICE-PCS). Am Heart J (2007) 1.26
Repeat infective endocarditis: differentiating relapse from reinfection. Clin Infect Dis (2005) 1.26
High-dose daptomycin therapy for left-sided infective endocarditis: a prospective study from the international collaboration on endocarditis. Antimicrob Agents Chemother (2013) 1.24
Staphylococcus aureus bacteremia and endocarditis. Infect Dis Clin North Am (2002) 1.24
Staphylococcus aureus bacteremia in patients with prosthetic devices: costs and outcomes. Am J Med (2005) 1.23
The Chlamydia protease CPAF regulates host and bacterial proteins to maintain pathogen vacuole integrity and promote virulence. Cell Host Microbe (2011) 1.21
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Staphylococcus aureus sortase transpeptidase SrtA: insight into the kinetic mechanism and evidence for a reverse protonation catalytic mechanism. Biochemistry (2005) 1.19
Coagulase-negative staphylococcal infections in the neonatal intensive care unit. Infect Control Hosp Epidemiol (2011) 1.19
Risk of endocarditis among patients with prosthetic valves and Staphylococcus aureus bacteremia. Am J Med (2005) 1.18
Development of a high-performance liquid chromatography assay and revision of kinetic parameters for the Staphylococcus aureus sortase transpeptidase SrtA. Anal Biochem (2004) 1.17
Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses. PLoS Pathog (2010) 1.17
Combinatorial phenotypic signatures distinguish persistent from resolving methicillin-resistant Staphylococcus aureus bacteremia isolates. Antimicrob Agents Chemother (2010) 1.13
Periannular complications in infective endocarditis involving prosthetic aortic valves. Am J Cardiol (2006) 1.11
Use of surgery in patients with native valve infective endocarditis: results from the International Collaboration on Endocarditis Merged Database. Am Heart J (2005) 1.11
Phase II, randomized, double-blind, multicenter study comparing the safety and pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia. Antimicrob Agents Chemother (2006) 1.10
Polymorphisms in fibronectin binding protein A of Staphylococcus aureus are associated with infection of cardiovascular devices. Proc Natl Acad Sci U S A (2011) 1.08
Outcomes of Staphylococcus aureus infection in hemodialysis-dependent patients. Clin J Am Soc Nephrol (2008) 1.08
A meta-analysis of medical versus surgical therapy for Candida endocarditis. J Infect (2004) 1.08
Mutagenesis studies of substrate recognition and catalysis in the sortase A transpeptidase from Staphylococcus aureus. J Biol Chem (2008) 1.07
Mutational analysis of active site residues in the Staphylococcus aureus transpeptidase SrtA. Biochemistry (2007) 1.07
Colonization, pathogenicity, host susceptibility, and therapeutics for Staphylococcus aureus: what is the clinical relevance? Semin Immunopathol (2011) 1.06
Frequency of infective endocarditis among infants and children with Staphylococcus aureus bacteremia. Pediatrics (2004) 1.05
Antibacterial resistance leadership group: open for business. Clin Infect Dis (2014) 1.04
Osteoblasts express the inflammatory cytokine interleukin-6 in a murine model of Staphylococcus aureus osteomyelitis and infected human bone tissue. Am J Pathol (2004) 1.04
Phosphorus-based SAHA analogues as histone deacetylase inhibitors. Org Lett (2003) 1.04
Presence of genes encoding panton-valentine leukocidin is not the primary determinant of outcome in patients with hospital-acquired pneumonia due to Staphylococcus aureus. J Clin Microbiol (2012) 1.04
Engineering the substrate specificity of Staphylococcus aureus Sortase A. The beta6/beta7 loop from SrtB confers NPQTN recognition to SrtA. J Biol Chem (2007) 1.03
Osteoblasts produce monocyte chemoattractant protein-1 in a murine model of Staphylococcus aureus osteomyelitis and infected human bone tissue. Bone (2005) 1.02
Using decision analysis to improve malaria control policy making. Health Policy (2009) 1.00
Vinyl sulfones: inhibitors of SrtA, a transpeptidase required for cell wall protein anchoring and virulence in Staphylococcus aureus. J Am Chem Soc (2004) 1.00
Potential associations between severity of infection and the presence of virulence-associated genes in clinical strains of Staphylococcus aureus. PLoS One (2011) 0.99
Use of pH and kinetic isotope effects to establish chemistry as rate-limiting in oxidation of a peptide substrate by LSD1. Biochemistry (2009) 0.99
Incidence of and preoperative risk factors for Staphylococcus aureus bacteremia and chest wound infection after cardiac surgery. Infect Control Hosp Epidemiol (2009) 0.99
Fatal outcome of bacteraemic patients caused by infection with staphylokinase-deficient Staphylococcus aureus strains. J Med Microbiol (2003) 0.99
Periannular complications in infective endocarditis involving native aortic valves. Am J Cardiol (2006) 0.99
Gene expression-based classifiers identify Staphylococcus aureus infection in mice and humans. PLoS One (2013) 0.99
Correlation between fundamental binding forces and clinical prognosis of Staphylococcus aureus infections of medical implants. Langmuir (2007) 0.98
Transmission of MRSA between companion animals and infected human patients presenting to outpatient medical care facilities. PLoS One (2011) 0.98
Influence of diabetes mellitus on the clinical manifestations and prognosis of infective endocarditis: a report from the International Collaboration on Endocarditis-Merged Database. Scand J Infect Dis (2006) 0.98