Published in Sci Rep on June 07, 2016
FUS inclusions disrupt RNA localization by sequestering kinesin-1 and inhibiting microtubule detyrosination. J Cell Biol (2017) 0.82
Dynein efficiently navigates the dendritic cytoskeleton to drive the retrograde trafficking of BDNF/TrkB signaling endosomes. Mol Biol Cell (2017) 0.76
The impact of cytoskeletal organization on the local regulation of neuronal transport. Nat Rev Neurosci (2017) 0.75
Insulin signaling regulates a functional interaction between Adenomatous Polyposis Coli (APC) and cytoplasmic dynein. Mol Biol Cell (2017) 0.75
Adenomatous polyposis coli nucleates actin assembly to drive cell migration and microtubule-induced focal adhesion turnover. J Cell Biol (2017) 0.75
NIH Image to ImageJ: 25 years of image analysis. Nat Methods (2012) 84.41
Fiji: an open-source platform for biological-image analysis. Nat Methods (2012) 56.92
Lessons from hereditary colorectal cancer. Cell (1996) 25.73
Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell (2009) 18.31
Identification and characterization of the familial adenomatous polyposis coli gene. Cell (1991) 14.46
Identification of a novel force-generating protein, kinesin, involved in microtubule-based motility. Cell (1985) 13.73
The establishment of polarity by hippocampal neurons in culture. J Neurosci (1988) 8.40
Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity. Nature (2003) 6.09
Kinesin superfamily motor proteins and intracellular transport. Nat Rev Mol Cell Biol (2009) 5.61
Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent. J Cell Biol (2006) 4.28
Microtubule assembly, organization and dynamics in axons and dendrites. Nat Rev Neurosci (2009) 4.13
NGF-induced axon growth is mediated by localized inactivation of GSK-3beta and functions of the microtubule plus end binding protein APC. Neuron (2004) 3.72
The APC gene product associates with microtubules in vivo and promotes their assembly in vitro. Cancer Res (1994) 3.57
Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease. Neuron (2010) 3.49
Miro1 is a calcium sensor for glutamate receptor-dependent localization of mitochondria at synapses. Neuron (2009) 3.49
Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites. Nature (2002) 3.16
Binding of the adenomatous polyposis coli protein to microtubules increases microtubule stability and is regulated by GSK3 beta phosphorylation. Curr Biol (2001) 3.13
A selective filter for cytoplasmic transport at the axon initial segment. Cell (2009) 3.09
Experimental observations on the development of polarity by hippocampal neurons in culture. J Cell Biol (1989) 2.86
STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER. Curr Biol (2008) 2.79
Tubulin tyrosination navigates the kinesin-1 motor domain to axons. Nat Neurosci (2009) 2.55
Microtubules provide directional cues for polarized axonal transport through interaction with kinesin motor head. J Cell Biol (2003) 2.39
Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells. J Cell Biol (2000) 2.33
Asef, a link between the tumor suppressor APC and G-protein signaling. Science (2000) 2.25
APC and GSK-3beta are involved in mPar3 targeting to the nascent axon and establishment of neuronal polarity. Curr Biol (2004) 2.09
Single molecule imaging reveals differences in microtubule track selection between Kinesin motors. PLoS Biol (2009) 2.06
Syntabulin is a microtubule-associated protein implicated in syntaxin transport in neurons. Nat Cell Biol (2004) 1.96
Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells. J Cell Sci (2008) 1.94
Identification of a link between the tumour suppressor APC and the kinesin superfamily. Nat Cell Biol (2002) 1.93
The adenomatous polyposis coli protein: the Achilles heel of the gut epithelium. Annu Rev Cell Dev Biol (2004) 1.90
APC is an RNA-binding protein, and its interactome provides a link to neural development and microtubule assembly. Cell (2014) 1.74
APC binds intermediate filaments and is required for their reorganization during cell migration. J Cell Biol (2013) 1.62
Kinesin superfamily protein 3 (KIF3) motor transports fodrin-associating vesicles important for neurite building. J Cell Biol (2000) 1.60
Regulation and function of the interaction between the APC tumour suppressor protein and EB1. Oncogene (2000) 1.60
Cell regulation by the Apc protein Apc as master regulator of epithelia. Curr Opin Cell Biol (2008) 1.53
GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking. Nat Neurosci (2005) 1.52
Adenomatous polyposis coli protein deletion leads to cognitive and autism-like disabilities. Mol Psychiatry (2014) 1.52
Wnt regulates axon behavior through changes in microtubule growth directionality: a new role for adenomatous polyposis coli. J Neurosci (2008) 1.50
Lack of adenomatous polyposis coli protein correlates with a decrease in cell migration and overall changes in microtubule stability. Mol Biol Cell (2006) 1.50
Dynamics of beta-catenin interactions with APC protein regulate epithelial tubulogenesis. J Cell Biol (1997) 1.45
From signaling pathways to microtubule dynamics: the key players. Curr Opin Cell Biol (2009) 1.42
Adenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1. Mol Biol Cell (2006) 1.42
Preferential binding of a kinesin-1 motor to GTP-tubulin-rich microtubules underlies polarized vesicle transport. J Cell Biol (2011) 1.41
Regulated binding of adenomatous polyposis coli protein to actin. J Biol Chem (2007) 1.41
Tight functional coupling of kinesin-1A and dynein motors in the bidirectional transport of neurofilaments. Mol Biol Cell (2009) 1.41
The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex. Neuron (2009) 1.39
Neurite outgrowth involves adenomatous polyposis coli protein and beta-catenin. J Cell Sci (2005) 1.34
Dissecting interactions between EB1, microtubules and APC in cortical clusters at the plasma membrane. J Cell Sci (2002) 1.33
Kinesin assembly and movement in cells. Annu Rev Biophys (2011) 1.32
Wnt signalling inhibits neural differentiation of embryonic stem cells by controlling bone morphogenetic protein expression. Mol Cell Neurosci (2003) 1.32
Role of adenomatous polyposis coli (APC) and microtubules in directional cell migration and neuronal polarization. Semin Cell Dev Biol (2008) 1.24
The role of Kif5B in axonal localization of Kv1 K(+) channels. Eur J Neurosci (2007) 1.24
Neuronal polarity is regulated by glycogen synthase kinase-3 (GSK-3beta) independently of Akt/PKB serine phosphorylation. J Cell Sci (2006) 1.22
KIF17 stabilizes microtubules and contributes to epithelial morphogenesis by acting at MT plus ends with EB1 and APC. J Cell Biol (2010) 1.21
Cargo selection by specific kinesin light chain 1 isoforms. EMBO J (2006) 1.21
Kinesin-1-syntaphilin coupling mediates activity-dependent regulation of axonal mitochondrial transport. J Cell Biol (2013) 1.18
KIF26A is an unconventional kinesin and regulates GDNF-Ret signaling in enteric neuronal development. Cell (2009) 1.14
Interactions and functions of the adenomatous polyposis coli (APC) protein at a glance. J Cell Sci (2013) 1.09
α-Tubulin Tyrosination and CLIP-170 Phosphorylation Regulate the Initiation of Dynein-Driven Transport in Neurons. Cell Rep (2016) 1.00
The adenomatous polyposis coli protein (APC) exists in two distinct soluble complexes with different functions. J Cell Sci (2005) 0.98
Adenomatous polyposis coli is differentially distributed in growth cones and modulates their steering. J Neurosci (2007) 0.98
Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin. J Biol Chem (2006) 0.96
Kinesin-1/Hsc70-dependent mechanism of slow axonal transport and its relation to fast axonal transport. EMBO J (2010) 0.93
The kinesin superfamily protein KIF17: one protein with many functions. Biomol Concepts (2012) 0.89
Putting the model to the test: are APC proteins essential for neuronal polarity, axon outgrowth, and axon targeting? J Cell Biol (2008) 0.87
Adenomatous polyposis coli localization is both cell type and cell context dependent. Cell Motil Cytoskeleton (2006) 0.87
The kinesin-2 family member KIF3C regulates microtubule dynamics and is required for axon growth and regeneration. J Neurosci (2013) 0.87
Suppression of kinesin expression disrupts adenomatous polyposis coli (APC) localization and affects beta-catenin turnover in young adult mouse colon (YAMC) epithelial cells. Exp Cell Res (2002) 0.85
Adenomatous polyposis coli regulates axon arborization and cytoskeleton organization via its N-terminus. PLoS One (2011) 0.85
APC protein is required for initiation of neuronal differentiation in rat pheochromocytoma PC12 cells. Biochem Biophys Res Commun (2000) 0.84
APC binds the Miro/Milton motor complex to stimulate transport of mitochondria to the plasma membrane. Mol Biol Cell (2015) 0.83
Subcellular localization of the tumor suppressor protein APC in developing cultured neurons. Neurosci Lett (2004) 0.82
The cellular distribution of the adenomatous polyposis coli tumour suppressor protein in neuroblastoma cells is regulated by microtubule dynamics. Neuroscience (1997) 0.81
The alpha-tubulin of the growth cone is predominantly in the tyrosinated form. Brain Res (1988) 0.80
A role for kinesin heavy chain in controlling vesicle transport into dendrites in Drosophila. Mol Biol Cell (2011) 0.80
The GRIP1/14-3-3 pathway coordinates cargo trafficking and dendrite development. Dev Cell (2014) 0.79
Endoplasmic reticulum sorting and kinesin-1 command the targeting of axonal GABAB receptors. PLoS One (2012) 0.78