Published in Nat Rev Neurosci on May 01, 2009
Three-dimensional, flexible nanoscale field-effect transistors as localized bioprobes. Science (2010) 4.13
Actin in dendritic spines: connecting dynamics to function. J Cell Biol (2010) 3.57
GSK3 signalling in neural development. Nat Rev Neurosci (2010) 3.29
The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease. Nat Rev Neurosci (2010) 3.14
Axonal transport defects in neurodegenerative diseases. J Neurosci (2009) 2.74
Cytoskeletal dynamics in growth-cone steering. J Cell Sci (2009) 1.87
Doublecortin recognizes the 13-protofilament microtubule cooperatively and tracks microtubule ends. Dev Cell (2012) 1.85
The MAP kinase phosphatase MKP-1 regulates BDNF-induced axon branching. Nat Neurosci (2010) 1.74
Super-resolution imaging reveals that loss of the C-terminus of connexin43 limits microtubule plus-end capture and NaV1.5 localization at the intercalated disc. Cardiovasc Res (2014) 1.59
Global up-regulation of microtubule dynamics and polarity reversal during regeneration of an axon from a dendrite. Mol Biol Cell (2010) 1.55
The emerging role of forces in axonal elongation. Prog Neurobiol (2011) 1.50
Molecular mechanisms of dendrite stability. Nat Rev Neurosci (2013) 1.44
A hitchhiker's guide to the nervous system: the complex journey of viruses and toxins. Nat Rev Microbiol (2010) 1.39
GSK3 controls axon growth via CLASP-mediated regulation of growth cone microtubules. Genes Dev (2011) 1.37
Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis. EMBO J (2010) 1.34
Post-translational modifications of tubulin: pathways to functional diversity of microtubules. Trends Cell Biol (2014) 1.33
Amyloid-β oligomers induce synaptic damage via Tau-dependent microtubule severing by TTLL6 and spastin. EMBO J (2013) 1.31
The centrosome neither persistently leads migration nor determines the site of axonogenesis in migrating neurons in vivo. J Cell Biol (2010) 1.29
Microtubule depolymerization in Caenorhabditis elegans touch receptor neurons reduces gene expression through a p38 MAPK pathway. Proc Natl Acad Sci U S A (2011) 1.25
Engineering neuronal growth cones to promote axon regeneration over inhibitory molecules. Proc Natl Acad Sci U S A (2011) 1.24
Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice. PLoS One (2010) 1.21
Beyond taxol: microtubule-based treatment of disease and injury of the nervous system. Brain (2013) 1.19
EB1-recruited microtubule +TIP complexes coordinate protrusion dynamics during 3D epithelial remodeling. Curr Biol (2012) 1.15
Impaired function of HDAC6 slows down axonal growth and interferes with axon initial segment development. PLoS One (2010) 1.14
The dynamic ubiquitin ligase duo: Cdh1-APC and Cdc20-APC regulate neuronal morphogenesis and connectivity. Curr Opin Neurobiol (2010) 1.14
Basic mechanisms for recognition and transport of synaptic cargos. Mol Brain (2009) 1.13
ProBDNF collapses neurite outgrowth of primary neurons by activating RhoA. PLoS One (2012) 1.11
Microtubule stabilization by bone morphogenetic protein receptor-mediated scaffolding of c-Jun N-terminal kinase promotes dendrite formation. Mol Cell Biol (2010) 1.10
Dendritic vulnerability in neurodegenerative disease: insights from analyses of cortical pyramidal neurons in transgenic mouse models. Brain Struct Funct (2010) 1.10
A novel GRK2/HDAC6 interaction modulates cell spreading and motility. EMBO J (2011) 1.08
Spectraplakins promote microtubule-mediated axonal growth by functioning as structural microtubule-associated proteins and EB1-dependent +TIPs (tip interacting proteins). J Neurosci (2012) 1.07
Viscoelasticity of tau proteins leads to strain rate-dependent breaking of microtubules during axonal stretch injury: predictions from a mathematical model. Biophys J (2014) 1.07
Building complexity: insights into self-organized assembly of microtubule-based architectures. Dev Cell (2012) 1.06
Immune synapse: conductor of orchestrated organelle movement. Trends Cell Biol (2013) 1.05
Drosophila katanin-60 depolymerizes and severs at microtubule defects. Biophys J (2011) 1.04
Branch management: mechanisms of axon branching in the developing vertebrate CNS. Nat Rev Neurosci (2014) 1.04
LRRK2 function on actin and microtubule dynamics in Parkinson disease. Commun Integr Biol (2010) 1.04
Translocation of CaMKII to dendritic microtubules supports the plasticity of local synapses. J Cell Biol (2012) 1.04
Antibody-drug conjugates as novel anti-cancer chemotherapeutics. Biosci Rep (2015) 1.03
Tau pathology is present in vivo and develops in vitro in sensory neurons from human P301S tau transgenic mice: a system for screening drugs against tauopathies. J Neurosci (2013) 1.02
Optically resolving individual microtubules in live axons. Structure (2009) 1.01
WNT signaling in neuronal maturation and synaptogenesis. Front Cell Neurosci (2013) 1.01
An assay to image neuronal microtubule dynamics in mice. Nat Commun (2014) 1.00
Computational modeling of axonal microtubule bundles under tension. Biophys J (2012) 1.00
An essential role for katanin p80 and microtubule severing in male gamete production. PLoS Genet (2012) 0.99
PTRN-1, a microtubule minus end-binding CAMSAP homolog, promotes microtubule function in Caenorhabditis elegans neurons. Elife (2014) 0.99
The functions of the actin nucleator Cobl in cellular morphogenesis critically depend on syndapin I. EMBO J (2011) 0.98
Cdc42-mediated inhibition of GSK-3β improves angio-architecture and lumen formation during VEGF-driven pathological angiogenesis. Microvasc Res (2010) 0.97
Tuning supramolecular mechanics to guide neuron development. Biomaterials (2013) 0.95
Microtubule-associated protein 1B (MAP1B) is required for dendritic spine development and synaptic maturation. J Biol Chem (2011) 0.95
Exclusion of integrins from CNS axons is regulated by Arf6 activation and the AIS. J Neurosci (2015) 0.94
A patient-derived stem cell model of hereditary spastic paraplegia with SPAST mutations. Dis Model Mech (2012) 0.94
Septins promote dendrite and axon development by negatively regulating microtubule stability via HDAC6-mediated deacetylation. Nat Commun (2013) 0.94
Microtubule dynamics in neuronal morphogenesis. Open Biol (2013) 0.94
FoxO limits microtubule stability and is itself negatively regulated by microtubule disruption. J Cell Biol (2012) 0.93
Growing the growth cone: remodeling the cytoskeleton to promote axon regeneration. Trends Neurosci (2011) 0.93
The Caenorhabditis elegans microtubule minus-end binding homolog PTRN-1 stabilizes synapses and neurites. Elife (2014) 0.93
Effects of kinesin-5 inhibition on dendritic architecture and microtubule organization. Mol Biol Cell (2014) 0.93
Rho GTPases at the crossroad of signaling networks in mammals: impact of Rho-GTPases on microtubule organization and dynamics. Small GTPases (2014) 0.92
Emergent complexity of the cytoskeleton: from single filaments to tissue. Adv Phys (2013) 0.92
VPS35 regulates developing mouse hippocampal neuronal morphogenesis by promoting retrograde trafficking of BACE1. Biol Open (2012) 0.91
Independent pathways downstream of the Wnd/DLK MAPKKK regulate synaptic structure, axonal transport, and injury signaling. J Neurosci (2013) 0.91
Mechanism of microtubule array expansion in the cytokinetic phragmoplast. Nat Commun (2013) 0.91
Glycan-dependent binding of galectin-1 to neuropilin-1 promotes axonal regeneration after spinal cord injury. Cell Death Differ (2014) 0.90
Bioinformatic analyses identifies novel protein-coding pharmacogenomic markers associated with paclitaxel sensitivity in NCI60 cancer cell lines. BMC Med Genomics (2011) 0.90
Intermediate filament-associated cytolinker plectin 1c destabilizes microtubules in keratinocytes. Mol Biol Cell (2013) 0.90
The suppression of CRMP2 expression by bone morphogenetic protein (BMP)-SMAD gradient signaling controls multiple stages of neuronal development. J Biol Chem (2010) 0.89
The formin FMNL3 is a cytoskeletal regulator of angiogenesis. J Cell Sci (2012) 0.89
Microtubule alterations occur early in experimental parkinsonism and the microtubule stabilizer epothilone D is neuroprotective. Sci Rep (2013) 0.89
Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation. J Neurosci (2016) 0.89
Engineered, harnessed, and hijacked: synthetic uses for cytoskeletal systems. Trends Cell Biol (2012) 0.88
Learning-induced and stathmin-dependent changes in microtubule stability are critical for memory and disrupted in ageing. Nat Commun (2014) 0.88
Protein tau: prime cause of synaptic and neuronal degeneration in Alzheimer's disease. Int J Alzheimers Dis (2012) 0.88
Directional spread of alphaherpesviruses in the nervous system. Viruses (2013) 0.88
Identification of the rare compound heterozygous variants in the NEB gene in a Korean family with intellectual disability, epilepsy and early-childhood-onset generalized muscle weakness. J Hum Genet (2014) 0.88
A human IgM signals axon outgrowth: coupling lipid raft to microtubules. J Neurochem (2011) 0.87
Measurement of subcellular force generation in neurons. Biophys J (2015) 0.87
The microtubule minus-end-binding protein patronin/PTRN-1 is required for axon regeneration in C. elegans. Cell Rep (2014) 0.87
A molecular and structural mechanism for G protein-mediated microtubule destabilization. J Biol Chem (2010) 0.87
A marginal band of microtubules transports and organizes mitochondria in retinal bipolar synaptic terminals. J Gen Physiol (2015) 0.87
Computational predictions of volatile anesthetic interactions with the microtubule cytoskeleton: implications for side effects of general anesthesia. PLoS One (2012) 0.86
The intricate relationship between microtubules and their associated motor proteins during axon growth and maintenance. Neural Dev (2013) 0.86
Dynamic microtubules drive circuit rewiring in the absence of neurite remodeling. Curr Biol (2015) 0.85
The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila. PLoS One (2013) 0.85
Neuronal polarity: demarcation, growth and commitment. Curr Opin Cell Biol (2012) 0.85
Evidence for the involvement of Lfc and Tctex-1 in axon formation. J Neurosci (2010) 0.85
Agomelatine (S20098) modulates the expression of cytoskeletal microtubular proteins, synaptic markers and BDNF in the rat hippocampus, amygdala and PFC. Psychopharmacology (Berl) (2011) 0.85
A PIK3C3-ankyrin-B-dynactin pathway promotes axonal growth and multiorganelle transport. J Cell Biol (2014) 0.85
Mechanical Effects of Dynamic Binding between Tau Proteins on Microtubules during Axonal Injury. Biophys J (2015) 0.85
Collapsin response mediator protein 4 regulates growth cone dynamics through the actin and microtubule cytoskeleton. J Biol Chem (2014) 0.84
Microtubule plus-end tracking protein CLASP2 regulates neuronal polarity and synaptic function. J Neurosci (2012) 0.84
Futsch/MAP1B mRNA is a translational target of TDP-43 and is neuroprotective in a Drosophila model of amyotrophic lateral sclerosis. J Neurosci (2014) 0.84
Functional complexity of the axonal growth cone: a proteomic analysis. PLoS One (2012) 0.84
Sun1 deficiency leads to cerebellar ataxia in mice. Dis Model Mech (2015) 0.83
Emerging roles of sumoylation in the regulation of actin, microtubules, intermediate filaments, and septins. Cytoskeleton (Hoboken) (2015) 0.83
The cytoskeleton and neurite initiation. Bioarchitecture (2014) 0.83
3β-Methoxy-pregnenolone (MAP4343) as an innovative therapeutic approach for depressive disorders. Proc Natl Acad Sci U S A (2012) 0.83
Increased spinal cord Na⁺-K⁺-2Cl⁻ cotransporter-1 (NKCC1) activity contributes to impairment of synaptic inhibition in paclitaxel-induced neuropathic pain. J Biol Chem (2014) 0.83
Microtubules, axonal transport, and neuropathy. N Engl J Med (2011) 0.83
Phosphorylation of actin-depolymerizing factor/cofilin by LIM-kinase mediates amyloid beta-induced degeneration: a potential mechanism of neuronal dystrophy in Alzheimer's disease. J Neurosci (2006) 1.35
LIMK1 regulates Golgi dynamics, traffic of Golgi-derived vesicles, and process extension in primary cultured neurons. Mol Biol Cell (2004) 1.35
IGF-1 receptor is essential for the establishment of hippocampal neuronal polarity. Nat Neurosci (2006) 1.31
MAP1B regulates axonal development by modulating Rho-GTPase Rac1 activity. Mol Biol Cell (2010) 1.17
PI3K activation by IGF-1 is essential for the regulation of membrane expansion at the nerve growth cone. J Cell Sci (2005) 1.17
Protein kinase d regulates trafficking of dendritic membrane proteins in developing neurons. J Neurosci (2008) 1.10
Regulation of membrane expansion at the nerve growth cone. J Cell Sci (2003) 1.08
The TC10-Exo70 complex is essential for membrane expansion and axonal specification in developing neurons. J Neurosci (2009) 1.06
Polarized traffic of LRP1 involves AP1B and SNX17 operating on Y-dependent sorting motifs in different pathways. Mol Biol Cell (2008) 1.01
IGF-1 activates a cilium-localized noncanonical Gβγ signaling pathway that regulates cell-cycle progression. Dev Cell (2013) 0.92
End binding protein-1 (EB1) complements microtubule-associated protein-1B during axonogenesis. J Neurosci Res (2005) 0.87
KIF4 mediates anterograde translocation and positioning of ribosomal constituents to axons. J Biol Chem (2009) 0.87
Evidence for the involvement of Lfc and Tctex-1 in axon formation. J Neurosci (2010) 0.85
ER-bound protein tyrosine phosphatase PTP1B interacts with Src at the plasma membrane/substrate interface. PLoS One (2012) 0.85
Rotenone-induced toxicity is mediated by Rho-GTPases in hippocampal neurons. Toxicol Sci (2008) 0.82
IQGAP1: A microtubule-microfilament scaffolding protein with multiple roles in nerve cell development and synaptic plasticity. Histol Histopathol (2012) 0.80
ENA/VASP downregulation triggers cell death by impairing axonal maintenance in hippocampal neurons. Mol Cell Neurosci (2010) 0.78