Skeletal muscle insulin resistance in hamsters with diabetes developed from obesity is involved in abnormal skeletal muscle LXR, PPAR and SREBP expression.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27284309)

Published in Exp Ther Med on March 31, 2016

Authors

Guo-Sheng Li1, Xu-Han Liu2, Hua Zhu3, Lan Huang3, Ya-Li Liu3, Chun-Mei Ma3

Author Affiliations

1: Department of Pathology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, P.R. China.
2: Department of Endocrinology, Dalian Municipal Central Hospital, Dalian, Liaoning 116033, P.R. China.
3: Department of Pathology, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences (CAMS) and Peking Union Medical College (PUMC), Beijing 100021, P.R. China.

Articles cited by this

Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1. Proc Natl Acad Sci U S A (2003) 17.10

Adiponectin and adiponectin receptors. Endocr Rev (2005) 8.46

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Nat Rev Mol Cell Biol (2008) 8.43

Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c. J Biol Chem (2002) 5.89

Role of the low density lipoprotein receptor in regulating the content of free and esterified cholesterol in human fibroblasts. J Clin Invest (1975) 3.18

Adiponectin--a key adipokine in the metabolic syndrome. Diabetes Obes Metab (2006) 2.58

Paradoxical effects of increased expression of PGC-1alpha on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism. Proc Natl Acad Sci U S A (2008) 2.49

Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice. J Biol Chem (2002) 2.40

The role of estrogens in control of energy balance and glucose homeostasis. Endocr Rev (2013) 1.93

Overexpression of uncoupling protein 3 in skeletal muscle protects against fat-induced insulin resistance. J Clin Invest (2007) 1.91

Physiological and pathophysiological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseases. Int J Obes (Lond) (2008) 1.75

Skeletal muscle-specific deletion of lipoprotein lipase enhances insulin signaling in skeletal muscle but causes insulin resistance in liver and other tissues. Diabetes (2008) 1.41

Lipotoxic diseases of nonadipose tissues in obesity. Int J Obes Relat Metab Disord (2000) 1.37

Dual role of interleukin-6 in regulating insulin sensitivity in murine skeletal muscle. Diabetes (2008) 1.34

Adiponectin resistance precedes the accumulation of skeletal muscle lipids and insulin resistance in high-fat-fed rats. Am J Physiol Regul Integr Comp Physiol (2008) 1.23

Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway. Biochem Biophys Res Commun (2009) 1.22

Glutathione peroxidase 3 mediates the antioxidant effect of peroxisome proliferator-activated receptor gamma in human skeletal muscle cells. Mol Cell Biol (2008) 1.20

Regulation of skeletal muscle hexokinase II by insulin in nondiabetic and NIDDM subjects. Diabetes (1998) 1.15

Skeletal muscle and nuclear hormone receptors: implications for cardiovascular and metabolic disease. Int J Biochem Cell Biol (2005) 1.08

Glucose induces de novo lipogenesis in rat muscle satellite cells through a sterol-regulatory-element-binding-protein-1c-dependent pathway. J Cell Sci (2004) 1.07

Is skeletal muscle mitochondrial dysfunction a cause or an indirect consequence of insulin resistance in humans? Diabetes Metab (2009) 1.02

Acyl-CoA inhibition of hexokinase in rat and human skeletal muscle is a potential mechanism of lipid-induced insulin resistance. Diabetes (2000) 1.01

LXR{beta} is the dominant LXR subtype in skeletal muscle regulating lipogenesis and cholesterol efflux. Am J Physiol Endocrinol Metab (2009) 0.91

The Genetics of PTPN1 and Obesity: Insights from Mouse Models of Tissue-Specific PTP1B Deficiency. J Obes (2012) 0.89

Sterol regulatory element-binding protein-1 mediates the effect of insulin on hexokinase II gene expression in human muscle cells. Diabetes (2004) 0.89

Adiponectin receptors form homomers and heteromers exhibiting distinct ligand binding and intracellular signaling properties. J Biol Chem (2012) 0.89

Role of liver X receptors in cholesterol efflux and inflammatory signaling (review). Mol Med Rep (2012) 0.88

Insulin resistance in insulin-resistant and diabetic hamsters (Mesocricetus auratus) is associated with abnormal hepatic expression of genes involved in lipid and glucose metabolism. Comp Med (2009) 0.84

Cardiovascular disease and PPARdelta: targeting the risk factors. Curr Opin Investig Drugs (2005) 0.84

Endogenous peroxisome proliferator-activated receptor-gamma augments fatty acid uptake in oxidative muscle. Endocrinology (2008) 0.83

Mouse hexokinase II gene: structure, cDNA, promoter analysis, and expression pattern. Mamm Genome (2000) 0.81

Cloning and expression of the genes associated with lipid metabolism in Tsaiya ducks. Poult Sci (2005) 0.79

18F9 (4-(3,6-bis (ethoxycarbonyl)-4,5,6,7-tetrahydrothieno (2,3-c) pyridin-2-ylamino)-4-oxobutanoic acid) enhances insulin-mediated glucose uptake in vitro and exhibits antidiabetic activity in vivo in db/db mice. Metabolism (2009) 0.78

Dietary modulators of peroxisome proliferator-activated receptors: implications for the prevention and treatment of metabolic syndrome. J Nutrigenet Nutrigenomics (2008) 0.78