Published in J Neurochem on July 15, 2016
MPP+ induces necrostatin-1- and ferrostatin-1-sensitive necrotic death of neuronal SH-SY5Y cells. Cell Death Discov (2017) 0.76
Dopaminergic Neuron-Specific Deletion of p53 Gene Attenuates Methamphetamine Neurotoxicity. Neurotox Res (2017) 0.75
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer. Nat Genet (2001) 9.55
Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis. Science (2004) 9.52
Unbiased stereological estimation of the number of neurons in the human hippocampus. J Comp Neurol (1990) 3.96
Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Ann Neurol (1999) 3.63
Dynamic reorganization of striatal circuits during the acquisition and consolidation of a skill. Nat Neurosci (2009) 3.38
High-frequency developmental abnormalities in p53-deficient mice. Curr Biol (1995) 2.57
Dysregulation of gene expression in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse substantia nigra. J Neurosci (2004) 2.24
Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus. Genesis (2006) 2.08
The role of glial reaction and inflammation in Parkinson's disease. Ann N Y Acad Sci (2003) 1.94
The p53-deficient mouse: a model for basic and applied cancer studies. Semin Cancer Biol (1996) 1.86
p53 in neuronal apoptosis. Biochem Biophys Res Commun (2005) 1.85
Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. Proc Natl Acad Sci U S A (2001) 1.62
Stages of motor skill learning. Mol Neurobiol (2005) 1.52
Classic and new animal models of Parkinson's disease. J Biomed Biotechnol (2012) 1.45
Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease. Proc Natl Acad Sci U S A (2007) 1.41
Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease. Nat Cell Biol (2009) 1.41
Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease. Exp Neurol (2000) 1.36
The role of glial cells in Parkinson's disease. Curr Opin Neurol (2001) 1.36
Delayed treatment with a p53 inhibitor enhances recovery in stroke brain. Ann Neurol (2009) 1.31
p53 protein, interferon-gamma, and NF-kappaB levels are elevated in the parkinsonian brain. Neurosci Lett (2006) 1.24
Role of ICAM-1 in persisting inflammation in Parkinson disease and MPTP monkeys. Exp Neurol (2005) 1.16
Developmental cell death in dopaminergic neurons of the substantia nigra of mice. J Comp Neurol (2000) 1.12
The regulation of cellular metabolism by tumor suppressor p53. Cell Biosci (2013) 1.12
Astrocytes and Parkinson's disease. Prog Brain Res (1992) 1.09
Synaptogenesis in the corpus striatum of infant rat. Exp Neurol (1973) 1.04
The survival of developing neurons: a review of afferent control. Neuroscience (1994) 1.04
Selective deletion of PTEN in dopamine neurons leads to trophic effects and adaptation of striatal medium spiny projecting neurons. PLoS One (2009) 1.00
Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease? J Neurochem (2001) 0.99
Apoptosis in Parkinson's disease: is p53 the missing link between genetic and sporadic Parkinsonism? Cell Signal (2010) 0.97
Dopamine neurons from transgenic mice with a knockout of the p53 gene resist MPTP neurotoxicity. Neurodegeneration (1996) 0.97
Programmed cell death during postnatal development of the rodent nervous system. Dev Growth Differ (2011) 0.97
P53- and CD95-associated apoptosis in neurodegenerative diseases. Lab Invest (1998) 0.94
ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1. J Cell Sci (2013) 0.93
Role of glial cells in neurotoxin-induced animal models of Parkinson's disease. Neurol Sci (2010) 0.92
PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice. Brain (2012) 0.91
Enhanced expression of glial fibrillary acidic protein and the cupric silver degeneration reaction can be used as sensitive and early indicators of neurotoxicity. Neurotoxicology (1992) 0.88
Decreased level of Nurr1 in heterozygous young adult mice leads to exacerbated acute and long-term toxicity after repeated methamphetamine exposure. PLoS One (2010) 0.87
p53-knockout mice are protected against the long-term effects of methamphetamine on dopaminergic terminals and cell bodies. J Neurochem (1997) 0.86
Two distinct knockout approaches highlight a critical role for p53 in rat development. Sci Rep (2012) 0.84
Inhibition of endothelial p53 improves metabolic abnormalities related to dietary obesity. Cell Rep (2014) 0.84
Temporal evolution of mouse striatal gene expression following MPTP injury. Neurobiol Aging (2005) 0.82
Aging of the dopaminergic system and motor behavior in mice intoxicated with the parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Neurochem (2012) 0.81
MPP+-induces PUMA- and p53-dependent, but ATF3-independent cell death. Toxicol Lett (2013) 0.81
The shh signaling pathway is upregulated in multiple cell types in cortical ischemia and influences the outcome of stroke in an animal model. PLoS One (2015) 0.79
Murine motor and behavior functional evaluations for acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxication. J Neuroimmune Pharmacol (2011) 0.79
Forebrain neuronal specific ablation of p53 gene provides protection in a cortical ischemic stroke model. Neuroscience (2015) 0.78
Differential Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine on Motor Behavior and Dopamine Levels at Brain Regions in Three Different Mouse Strains. Korean J Physiol Pharmacol (2013) 0.78