Published in Proc Natl Acad Sci U S A on June 01, 1989
Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly. J Cell Biol (1992) 7.97
Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape. Proc Natl Acad Sci U S A (1991) 3.01
Integrins, oncogenes, and anchorage independence. J Cell Biol (1997) 2.86
Control of intracellular pH and growth by fibronectin in capillary endothelial cells. J Cell Biol (1990) 2.41
Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms. J Cell Biol (1993) 2.38
Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium. J Cell Biol (1993) 1.97
Recent progress in tumor pH targeting nanotechnology. J Control Release (2008) 1.94
The Na+/H+ antiporter cytoplasmic domain mediates growth factor signals and controls "H(+)-sensing". Proc Natl Acad Sci U S A (1992) 1.83
Beta 1 integrin is essential for teratoma growth and angiogenesis. J Cell Biol (1997) 1.75
Integrin alpha 5 beta 1 expression negatively regulates cell growth: reversal by attachment to fibronectin. Mol Biol Cell (1995) 1.60
Na-H exchange acts downstream of RhoA to regulate integrin-induced cell adhesion and spreading. Mol Biol Cell (1998) 1.44
Loss of matrix adhesion triggers rapid transformation-selective apoptosis in fibroblasts. J Cell Biol (1997) 1.38
Adhesion is required for protein kinase C-dependent activation of the Na+/H+ antiporter by platelet-derived growth factor. Proc Natl Acad Sci U S A (1992) 1.34
Reduced contact-inhibition and substratum adhesion in epithelial cells expressing GlcNAc-transferase V. J Cell Biol (1995) 1.31
Focal adhesion targeting: the critical determinant of FAK regulation and substrate phosphorylation. Mol Biol Cell (1999) 1.29
Spreading of HeLa cells on a collagen substratum requires a second messenger formed by the lipoxygenase metabolism of arachidonic acid released by collagen receptor clustering. Mol Biol Cell (1992) 1.22
Fidelity of DNA synthesis catalyzed by human DNA polymerase alpha and HIV-1 reverse transcriptase: effect of reaction pH. Nucleic Acids Res (1993) 1.15
Trophic factor withdrawal: p38 mitogen-activated protein kinase activates NHE1, which induces intracellular alkalinization. Mol Cell Biol (2001) 1.12
A virus-mimetic nanogel vehicle. Angew Chem Int Ed Engl (2008) 1.05
Cytotactin binding: inhibition of stimulated proliferation and intracellular alkalinization in fibroblasts. Proc Natl Acad Sci U S A (1991) 0.99
Interactions of ion transporters and channels with cancer cell metabolism and the tumour microenvironment. Philos Trans R Soc Lond B Biol Sci (2014) 0.92
Role of the beta3 integrin subunit in human primary melanoma progression: multifunctional activities associated with alpha(v)beta3 integrin expression. Am J Pathol (1998) 0.92
Na+/H+ exchange activity during phagocytosis in human neutrophils: role of Fcgamma receptors and tyrosine kinases. J Cell Biol (1996) 0.88
cAMP accelerates the decay of stretch-activated inward currents in guinea-pig urinary bladder myocytes. J Physiol (1995) 0.86
Substratum-growth factor collaborations are required for the mitogenic activities of activin and FGF on embryonal carcinoma cells. J Cell Biol (1991) 0.83
Research advances on structure and biological functions of integrins. Springerplus (2016) 0.79
Intercellular redistribution of cAMP underlies selective suppression of cancer cell growth by connexin26. PLoS One (2013) 0.78
Bioabsorbable zinc ion induced biphasic cellular responses in vascular smooth muscle cells. Sci Rep (2016) 0.76
Modelling biological cell attachment and growth on adherent surfaces. J Math Biol (2013) 0.75
Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature (1983) 19.76
Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule. Nature (1984) 14.25
Role of cell shape in growth control. Nature (1978) 12.46
Intracellular pH measurements in Ehrlich ascites tumor cells utilizing spectroscopic probes generated in situ. Biochemistry (1979) 11.28
The molecular genetics of cancer. Science (1987) 7.64
Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium. Cell (1974) 6.18
Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src. Cell (1987) 5.84
Functional role for c-myc in mitogenic response to platelet-derived growth factor. Nature (1984) 4.56
Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-adipocytes. Cell (1983) 3.19
A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pH. Proc Natl Acad Sci U S A (1984) 3.07
Protein synthesis requires cell-surface contact while nuclear events respond to cell shape in anchorage-dependent fibroblasts. Cell (1980) 2.80
Flat revertants isolated from Kirsten sarcoma virus-transformed cells are resistant to the action of specific oncogenes. Proc Natl Acad Sci U S A (1983) 2.44
Cell-cell and cell-matrix interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes. Proc Natl Acad Sci U S A (1988) 2.30
Fluorescence ratio imaging microscopy: temporal and spatial measurements of cytoplasmic pH. J Cell Biol (1987) 2.28
Effects of growth factors on intracellular pH regulation. Annu Rev Physiol (1986) 2.25
The control of mRNA production, translation and turnover in suspended and reattached anchorage-dependent fibroblasts. Cell (1978) 2.19
Blockade of the Na+/H+ antiport abolishes growth factor-induced DNA synthesis in fibroblasts. Structure-activity relationships in the amiloride series. J Biol Chem (1984) 1.85
Induction of chondrogenesis in limb mesenchymal cultures by disruption of the actin cytoskeleton. J Cell Biol (1984) 1.82
Regulation of rat mammary gene expression by extracellular matrix components. Exp Cell Res (1987) 1.75
Changes in cell shape correlate with collagenase gene expression in rabbit synovial fibroblasts. J Cell Biol (1984) 1.67
Increased pH and tumorigenicity of fibroblasts expressing a yeast proton pump. Nature (1988) 1.57
Mechanisms that regulate the structural and functional architecture of cell surfaces. Int Rev Cytol (1982) 1.53
Interaction of serum and cell spreading affects the growth of neoplastic and non-neoplastic fibroblasts. J Supramol Struct Cell Biochem (1981) 1.20
Intracellular pH is increased after transformation of Chinese hamster embryo fibroblasts. Proc Natl Acad Sci U S A (1987) 1.13
Relationship between cytoplasmic pH and proliferation during exponential growth and cellular quiescence. Exp Cell Res (1987) 1.10
In vitro regulation of granulosa cell differentiation. Involvement of cytoskeletal protein expression. J Biol Chem (1987) 1.07
Induction of v-mos and activated Ha-ras oncogene expression in quiescent NIH 3T3 cells causes intracellular alkalinisation and cell-cycle progression. Gene (1987) 0.96
Amiloride analogues inhibit proximal tubule metabolism. Am J Physiol (1986) 0.83
Vanadate is a potent (Na,K)-ATPase inhibitor found in ATP derived from muscle. J Biol Chem (1977) 5.16
Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape. Proc Natl Acad Sci U S A (1991) 3.01
Control of intracellular pH and growth by fibronectin in capillary endothelial cells. J Cell Biol (1990) 2.41
Multiple integrins share the ability to induce elevation of intracellular pH. Exp Cell Res (1991) 1.67
Acute renal failure with selective medullary injury in the rat. J Clin Invest (1988) 1.62
Adhesion is required for protein kinase C-dependent activation of the Na+/H+ antiporter by platelet-derived growth factor. Proc Natl Acad Sci U S A (1992) 1.34
Renal epithelial cyst formation and enlargement in vitro: dependence on cAMP. Proc Natl Acad Sci U S A (1989) 1.19
ADH-PGE2 interactions in cortical collecting tubule. I. Depression of sodium transport. Am J Physiol (1981) 1.11
Measure of carbon and nitrogen stable isotope ratios in cultured cells. J Am Soc Mass Spectrom (2004) 1.07
Acute metabolic acidosis augments collecting duct acidification rate in the rat. Am J Physiol (1981) 1.00
Effect of urea concentration of pelvic fluid on renal concentrating ability. Am J Physiol (1980) 0.94
Electron-probe analysis of cultured cells. Ann N Y Acad Sci (1986) 0.92
Direct determination of free fatty acid transport across the adipocyte plasma membrane using quantitative fluorescence microscopy. J Biol Chem (1991) 0.90
CN- secondary ions form by recombination as demonstrated using multi-isotope mass spectrometry of 13C- and 15N-labeled polyglycine. J Am Soc Mass Spectrom (2006) 0.90
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Preparation of individual human diploid fibroblasts and study of ion transport. Am J Physiol (1985) 0.88
Technical problems associated with collection of distal tubular fluid in the rat. Yale J Biol Med (1973) 0.86
Coupling of Na-H exchange and Na-K pump activity in cultured rat proximal tubule cells. Am J Physiol (1986) 0.86
Pancreatic zymogen granules differ markedly in protein composition. Science (1986) 0.85
Electron probe microanalysis of biological soft tissues: principle and technique. Fed Proc (1980) 0.84
Fluorescence analysis of picoliter samples. Anal Biochem (1980) 0.83
Effect of parathyroid hormone on phosphate reabsorption in rat distal convolution. Am J Physiol (1978) 0.83
Renal medullary concentrating process: an integrative hypothesis. Am J Physiol (1980) 0.83
Water diuretic and natriuretic effect of clonidine in the rat. J Pharmacol Exp Ther (1979) 0.83
Cellular volume and cytoplasmic gel. Biol Cell (1985) 0.83
Alanine stimulation of passive potassium efflux in hepatocytes is independent of Na(+)-K+ pump activity. Am J Physiol (1990) 0.83
Ionic transport in individual renal epithelial cells from adult and young rats. Acta Physiol Scand (1986) 0.82
Distal site of action of parathyroid hormone on phosphate reabsorption. Am J Physiol (1975) 0.82
Cellular electrolyte and volume changes induced by acidosis in the rabbit proximal straight tubule. J Am Soc Nephrol (1991) 0.81
Prostaglandin E2 and F2 alpha reduces urea reabsorption from the rat collecting duct. Am J Physiol (1981) 0.80
Nucleotides in a single mammalian ovum or preimplantation embryo. Anal Biochem (1984) 0.80
An NADH-coupled assay for femtogram or nanogram quantities of chymotrypsin. Anal Biochem (1983) 0.80
ADH-PGE2 interactions in cortical collecting tubule. II. inhibition of Ca and P reabsorption. Am J Physiol (1981) 0.80
Electron-probe analysis of isolated goldfish hair cells: implications for preparing healthy cells. Hear Res (1993) 0.80
Intracellular ion concentrations and their maintenance by Na+/K(+)-ATPase in preimplantation mouse embryos. Zygote (1997) 0.80
Relief from alkaline load in two-cell stage mouse embryos by bicarbonate/chloride exchange. J Biol Chem (1991) 0.79
Rapid resting ion fluxes in goldfish hair cells are balanced by (Na+,K+)-ATPase. Hear Res (1993) 0.79
Fluorescence assay for picomole quantities of ammonia. Kidney Int (1982) 0.79
Prostaglandin-vasopressin interactions on the renal handling of calcium and magnesium. J Pharmacol Exp Ther (1984) 0.79
Two-cell stage mouse embryos appear to lack mechanisms for alleviating intracellular acid loads. J Biol Chem (1991) 0.78
A novel H+ permeability dominating intracellular pH in the early mouse embryo. Development (1993) 0.78
Rescue of a wild-type MDCK cell by a ouabain-resistant mutant. Am J Physiol (1987) 0.78
Studies on terminal differentiation of rat renal proximal tubular cells in culture: ouabain-sensitive K and Na transport. Acta Physiol Scand (1988) 0.78
Proximal tubule volume regulation in hyperosmotic media: intracellular K+, Na+, and Cl-. Am J Physiol (1989) 0.78
Renal tubule ion transport and collecting duct function in the elasmobranch little skate, Raja erinacea. J Exp Zool (1977) 0.78
Studies on final differentiation of rat renal proximal tubular cells in culture. Am J Physiol (1986) 0.77
Meclofenamate and urine concentration with and without exposure of the renal papilla. Am J Physiol (1981) 0.77
Isosmotic volume reabsorption in rat proximal tubule. J Gen Physiol (1980) 0.77
Extracellular N-methyl-D-glucamine leads to loss of hair-cell sodium, potassium, and chloride. Hear Res (1993) 0.76
Sodium and chloride transport along the inner medullary collecting duct: effect of saline expansion. Am J Physiol (1980) 0.76
Apparent absence of Na+/H+ antiport activity in the two-cell mouse embryo. Dev Biol (1990) 0.76
Analysis of proximal tubule salt and water transport in standing droplets. J Theor Biol (1979) 0.76
Use of experimental models to study the development of renal function. Biol Neonate (1988) 0.76
cAMP activates the sodium pump in cultured cells of the elasmobranch rectal gland. J Am Soc Nephrol (1992) 0.76
Noninvasive measurement of glucose uptake by two populations of murine embryos. Biol Reprod (1988) 0.76
Changes in Na influx precede post-natal increase in Na, K-ATPase activity in rat renal proximal tubular cells. Acta Physiol Scand (1990) 0.76
Analysis of standing droplets in rat proximal tubules. J Gen Physiol (1982) 0.75
[Investigations on the occurrence of Salmonella in clinically unsuspected pig breeding farms (author's transl)]. Dtsch Tierarztl Wochenschr (1982) 0.75
Studies of terminal differentiation of electrolyte transport in the renal proximal tubule using short-term primary cultures. Pediatr Nephrol (1989) 0.75
Calcium and magnesium transport by isolated goldfish hair cells. Hear Res (1993) 0.75
Ouabain-resistant, amiloride-sensitive Na+-K+ pumping activity and morphological changes are inducible. Am J Physiol (1988) 0.75
Role of renal prostaglandins in the fall in urine osmolality after papillary micropuncture. Prostaglandins (1985) 0.75
(Na,K)-pump: cellular role and regulation in nonexcitable cells. Biol Cell (1989) 0.75
Analysis of ultra small volumes in physiology with electron probe microanalysis. Microsc Acta Suppl (1978) 0.75
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[Report on an experiment in practice to treat fertility disturbances in swine with homeopathic preparations (author's transl)]. Dtsch Tierarztl Wochenschr (1980) 0.75
Proximal tubule volume regulation in hypo-osmotic media: intracellular K+, Na+, and Cl-. J Am Soc Nephrol (1990) 0.75
Electron probe analysis of small populations of single cells. Prog Clin Biol Res (1983) 0.75
Elemental analysis of biological specimens in air with a proton microprobe. Science (1976) 0.75
Effect of phosphate deprivation on phosphate reabsorption in rat nephron: role of PTH. Am J Physiol (1983) 0.75
[Research on the suitability of an allergic intracutaneous test in the diagnosis of brucellosis in pigs]. Berl Munch Tierarztl Wochenschr (1967) 0.75
Sodium orthovanadate diuresis in rats. J Pharmacol Exp Ther (1981) 0.75