Published in J Immunol on July 01, 2016
The Human Leukocyte Antigen (HLA)-B27 Peptidome in Vivo, in Spondyloarthritis-susceptible HLA-B27 Transgenic Rats and the Effect of Erap1 Deletion. Mol Cell Proteomics (2017) 0.76
ERAP1 overexpression in HPV-induced malignancies: A possible novel immune evasion mechanism. Oncoimmunology (2017) 0.76
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
WebLogo: a sequence logo generator. Genome Res (2004) 59.58
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat Genet (2010) 8.48
The ubiquitin code. Annu Rev Biochem (2012) 7.08
Towards a systems understanding of MHC class I and MHC class II antigen presentation. Nat Rev Immunol (2011) 4.31
ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum. Nature (2002) 3.72
Skin immune sentinels in health and disease. Nat Rev Immunol (2009) 3.52
Pathways of antigen processing. Annu Rev Immunol (2013) 2.82
Genome-wide association analysis identifies three psoriasis susceptibility loci. Nat Genet (2010) 2.76
Accurate approximation method for prediction of class I MHC affinities for peptides of length 8, 10 and 11 using prediction tools trained on 9mers. Bioinformatics (2008) 2.69
In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides. Nat Immunol (2006) 2.62
Producing nature's gene-chips: the generation of peptides for display by MHC class I molecules. Annu Rev Immunol (2001) 2.51
Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles. Immunogenetics (2004) 2.49
The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules. Nat Immunol (2005) 2.24
Identification of a Tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen. Cell (1994) 1.92
In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules. J Exp Med (2006) 1.79
The specific regulation of immune responses by CD8+ T cells restricted by the MHC class Ib molecule, Qa-1. Annu Rev Immunol (2000) 1.68
Characterizing the N-terminal processing motif of MHC class I ligands. J Immunol (2008) 1.68
Molecular mimicry mediated by MHC class Ib molecules after infection with gram-negative pathogens. Nat Med (2000) 1.51
Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells. J Immunol (2010) 1.46
The MHC class I peptide repertoire is molded by the transcriptome. J Exp Med (2008) 1.31
Qa-2 molecules are peptide receptors of higher stringency than ordinary class I molecules. Nature (1993) 1.23
Calreticulin-dependent recycling in the early secretory pathway mediates optimal peptide loading of MHC class I molecules. EMBO J (2009) 1.23
Analysis of Qa-1(b) peptide binding specificity and the capacity of CD94/NKG2A to discriminate between Qa-1-peptide complexes. J Exp Med (2000) 1.23
Regulation of Qa-1 expression and determinant modification by an H-2D-linked gene, Qdm. Immunogenetics (1988) 1.18
Prediction of peptide-MHC binding using profiles. Methods Mol Biol (2007) 1.16
Functional interaction of the ankylosing spondylitis-associated endoplasmic reticulum aminopeptidase 1 polymorphism and HLA-B27 in vivo. Mol Cell Proteomics (2012) 1.15
A nonpolymorphic major histocompatibility complex class Ib molecule binds a large array of diverse self-peptides. J Exp Med (1994) 1.14
Nonclassical MHC class Ib-restricted cytotoxic T cells monitor antigen processing in the endoplasmic reticulum. Nat Immunol (2012) 1.14
The nonpolymorphic MHC Qa-1b mediates CD8+ T cell surveillance of antigen-processing defects. J Exp Med (2009) 1.05
Peptide-receptive major histocompatibility complex class I molecules cycle between endoplasmic reticulum and cis-Golgi in wild-type lymphocytes. J Biol Chem (2007) 1.03
Presentation of endogenous peptide/MHC class I complexes is profoundly influenced by specific C-terminal flanking residues. J Immunol (1995) 1.03
Insights into MHC class I antigen processing gained from large-scale analysis of class I ligands. Cell Mol Life Sci (2011) 1.02
Positive selection of a Qa-1-restricted T cell receptor with specificity for insulin. Immunity (2002) 1.00
Origin and plasticity of MHC I-associated self peptides. Autoimmun Rev (2011) 0.99
The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation. Mol Syst Biol (2011) 0.96
A functional variant in ERAP1 predisposes to multiple sclerosis. PLoS One (2012) 0.93
Deletion of immunoproteasome subunits imprints on the transcriptome and has a broad impact on peptides presented by major histocompatibility complex I molecules. Mol Cell Proteomics (2010) 0.92
The transporter associated with antigen processing (TAP) is active in a post-ER compartment. J Cell Sci (2010) 0.89
ERAP1 and ankylosing spondylitis. Curr Opin Immunol (2013) 0.88
Alternative peptide binding motifs of Qa-2 class Ib molecules define rules for binding of self and nonself peptides. J Immunol (1997) 0.87
Genetic association with ERAP1 in psoriasis is confined to disease onset after puberty and not dependent on HLA-C*06. J Invest Dermatol (2012) 0.86
Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Polymorphism Relevant to Inflammatory Disease Shapes the Peptidome of the Birdshot Chorioretinopathy-Associated HLA-A*29:02 Antigen. Mol Cell Proteomics (2015) 0.84
Expression of the mouse MHC class Ib H2-T11 gene product, a paralog of H2-T23 (Qa-1) with shared peptide-binding specificity. J Immunol (2014) 0.80
Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames. Nat Commun (2016) 0.88
Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells. J Immunol (2015) 0.79
Proteogenomic-based discovery of minor histocompatibility antigens with suitable features for immunotherapy of hematologic cancers. Leukemia (2016) 0.78
An Unbiased Linkage Approach Reveals That the p53 Pathway Is Coupled to NK Cell Maturation. J Immunol (2017) 0.75
Major vs minor histocompatibility antigens. Blood (2017) 0.75
Exploiting non-canonical translation to identify new targets for T cell-based cancer immunotherapy. Cell Mol Life Sci (2017) 0.75
IFN-λ Enhances Constitutive Expression of MHC Class I Molecules on Thymic Epithelial Cells. J Immunol (2020) 0.75