Published in Nat Rev Immunol on November 11, 2011
Cytomegalovirus vectors violate CD8+ T cell epitope recognition paradigms. Science (2013) 3.27
Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME. Arch Toxicol (2013) 3.00
Widespread impact of HLA restriction on immune control and escape pathways of HIV-1. J Virol (2012) 1.62
β2-Glycoprotein I/HLA class II complexes are novel autoantigens in antiphospholipid syndrome. Blood (2015) 1.42
Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures. Genome Biol (2016) 1.41
The Salmonella Effector SteD Mediates MARCH8-Dependent Ubiquitination of MHC II Molecules and Inhibits T Cell Activation. Cell Host Microbe (2016) 1.39
Immunoproteasomes: structure, function, and antigen presentation. Prog Mol Biol Transl Sci (2012) 1.36
The anti-inflammatory mechanisms of Hsp70. Front Immunol (2012) 1.31
Unconventional recognition of peptides by T cells and the implications for autoimmunity. Nat Rev Immunol (2012) 1.29
Overview of proteasome inhibitor-based anti-cancer therapies: perspective on bortezomib and second generation proteasome inhibitors versus future generation inhibitors of ubiquitin-proteasome system. Curr Cancer Drug Targets (2014) 1.29
The determinants of tumour immunogenicity. Nat Rev Cancer (2012) 1.28
Kinetics of antigen expression and epitope presentation during virus infection. PLoS Pathog (2013) 1.21
NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens. Cell Res (2012) 1.21
An evolving new paradigm: endothelial cells--conditional innate immune cells. J Hematol Oncol (2013) 1.17
Idiosyncratic adverse drug reactions: current concepts. Pharmacol Rev (2013) 1.12
Expanding the detectable HLA peptide repertoire using electron-transfer/higher-energy collision dissociation (EThcD). Proc Natl Acad Sci U S A (2014) 1.11
Mass spectrometry of human leukocyte antigen class I peptidomes reveals strong effects of protein abundance and turnover on antigen presentation. Mol Cell Proteomics (2015) 1.08
The human CD8+ T cell responses induced by a live attenuated tetravalent dengue vaccine are directed against highly conserved epitopes. J Virol (2014) 1.08
The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain. J Exp Med (2012) 1.07
Parasite fate and involvement of infected cells in the induction of CD4+ and CD8+ T cell responses to Toxoplasma gondii. PLoS Pathog (2014) 1.07
Broadly targeted CD8⁺ T cell responses restricted by major histocompatibility complex E. Science (2016) 1.06
Effects of Peptide on NK cell-mediated MHC I recognition. Front Immunol (2014) 1.04
Role of microglia in CNS autoimmunity. Clin Dev Immunol (2013) 1.02
Delta-24-RGD oncolytic adenovirus elicits anti-glioma immunity in an immunocompetent mouse model. PLoS One (2014) 1.02
Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides. Nat Commun (2014) 1.01
Antigen Processing for MHC Class II Presentation via Autophagy. Front Immunol (2012) 0.99
Unraveling the evolution of the Atlantic cod's (Gadus morhua L.) alternative immune strategy. PLoS One (2013) 0.98
Heat-shock proteins as dendritic cell-targeting vaccines--getting warmer. Immunology (2013) 0.98
Aminopeptidase substrate preference affects HIV epitope presentation and predicts immune escape patterns in HIV-infected individuals. J Immunol (2012) 0.98
Presentation of phagocytosed antigens by MHC class I and II. Traffic (2012) 0.98
Comprehensive analysis of MHC class II genes in teleost fish genomes reveals dispensability of the peptide-loading DM system in a large part of vertebrates. BMC Evol Biol (2013) 0.97
Evolution of the immune system influences speciation rates in teleost fishes. Nat Genet (2016) 0.96
Mathematical modeling of escape of HIV from cytotoxic T lymphocyte responses. J Stat Mech (2013) 0.95
On the perils of poor editing: regulation of peptide loading by HLA-DQ and H2-A molecules associated with celiac disease and type 1 diabetes. Expert Rev Mol Med (2012) 0.95
Tale of a tegument transactivator: the past, present and future of human CMV pp71. Future Virol (2012) 0.94
Modulation of the autophagy pathway by human tumor viruses. Semin Cancer Biol (2013) 0.93
Adaptive immune activation: glycosylation does matter. Nat Chem Biol (2013) 0.93
HLA-F and MHC-I open conformers cooperate in a MHC-I antigen cross-presentation pathway. J Immunol (2013) 0.92
Functional specialization of islet dendritic cell subsets. J Immunol (2012) 0.92
Targeting dendritic cells: a promising strategy to improve vaccine effectiveness. Clin Transl Immunology (2016) 0.92
The nature and extent of contributions by defective ribosome products to the HLA peptidome. Proc Natl Acad Sci U S A (2014) 0.92
Macrophages clean up: efferocytosis and microbial control. Curr Opin Microbiol (2013) 0.92
Tetherin promotes the innate and adaptive cell-mediated immune response against retrovirus infection in vivo. J Immunol (2014) 0.90
The role of neoantigens in response to immune checkpoint blockade. Int Immunol (2016) 0.90
Into the intracellular logistics of cross-presentation. Front Immunol (2012) 0.90
HLA-DO and Its Role in MHC Class II Antigen Presentation. Front Immunol (2013) 0.90
The ubiquitin proteasome system and myocardial ischemia. Am J Physiol Heart Circ Physiol (2012) 0.90
Transport of misfolded endoplasmic reticulum proteins to the cell surface by MHC class II molecules. Int Immunol (2013) 0.90
Using intein catalysis to probe the origin of major histocompatibility complex class I-presented peptides. Proc Natl Acad Sci U S A (2012) 0.89
Distinct assembly profiles of HLA-B molecules. J Immunol (2014) 0.89
The effect of proteasome inhibition on the generation of the human leukocyte antigen (HLA) peptidome. Mol Cell Proteomics (2013) 0.89
Cytomegalovirus immune evasion by perturbation of endosomal trafficking. Cell Mol Immunol (2014) 0.89
The major histocompatibility complex and autism spectrum disorder. Dev Neurobiol (2012) 0.88
Equine Herpesvirus 1 Multiply Inserted Transmembrane Protein pUL43 Cooperates with pUL56 in Downregulation of Cell Surface Major Histocompatibility Complex Class I. J Virol (2015) 0.87
Narrow groove and restricted anchors of MHC class I molecule BF2*0401 plus peptide transporter restriction can explain disease susceptibility of B4 chickens. J Immunol (2012) 0.87
Us3 kinase encoded by herpes simplex virus 1 mediates downregulation of cell surface major histocompatibility complex class I and evasion of CD8+ T cells. PLoS One (2013) 0.87
The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1. Nat Immunol (2016) 0.87
Autoantibodies to IgG/HLA class II complexes are associated with rheumatoid arthritis susceptibility. Proc Natl Acad Sci U S A (2014) 0.86
Direct evidence that the N-terminal extensions of the TAP complex act as autonomous interaction scaffolds for the assembly of the MHC I peptide-loading complex. Cell Mol Life Sci (2012) 0.86
Monitoring peptide processing for MHC class I molecules in the endoplasmic reticulum. Curr Opin Immunol (2013) 0.86
Genetic variants within the MHC region are associated with immune responsiveness to childhood vaccinations. Vaccine (2013) 0.86
Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein. PLoS One (2012) 0.86
Naturally processed non-canonical HLA-A*02:01 presented peptides. J Biol Chem (2014) 0.86
Major histocompatibility complex class II+ invariant chain negative breast cancer cells present unique peptides that activate tumor-specific T cells from breast cancer patients. Mol Cell Proteomics (2012) 0.85
Genetic variants in antigen presentation-related genes influence susceptibility to hepatitis C virus and viral clearance: a case control study. BMC Infect Dis (2014) 0.85
Comprehensive Analysis of the Naturally Processed Peptide Repertoire: Differences between HLA-A and B in the Immunopeptidome. PLoS One (2015) 0.85
Polysaccharide A from the capsule of Bacteroides fragilis induces clonal CD4+ T cell expansion. J Biol Chem (2014) 0.84
Two polymorphisms facilitate differences in plasticity between two chicken major histocompatibility complex class I proteins. PLoS One (2014) 0.84
Spinal cord pathology in chronic experimental Toxoplasma gondii infection. Eur J Microbiol Immunol (Bp) (2014) 0.84
The first step of peptide selection in antigen presentation by MHC class I molecules. Proc Natl Acad Sci U S A (2015) 0.84
Epitope-specificity of recombinant antibodies reveals promiscuous peptide-binding properties. Protein Sci (2012) 0.84
A peptide's perspective on antigen presentation to the immune system. Nat Chem Biol (2013) 0.84
IRF1 and NF-kB restore MHC class I-restricted tumor antigen processing and presentation to cytotoxic T cells in aggressive neuroblastoma. PLoS One (2012) 0.84
ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion. EBioMedicine (2017) 0.84
Automatic Generation of Validated Specific Epitope Sets. J Immunol Res (2015) 0.84
Selector function of MHC I molecules is determined by protein plasticity. Sci Rep (2015) 0.84
p53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1. Nat Commun (2013) 0.84
MHC and Evolution in Teleosts. Biology (Basel) (2016) 0.83
MHC class II antigen presentation by dendritic cells regulated through endosomal sorting. Cold Spring Harb Perspect Biol (2013) 0.83
Association of polymorphisms in HLA antigen presentation-related genes with the outcomes of HCV infection. PLoS One (2015) 0.83
Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer. Int J Mol Sci (2012) 0.83
PolyCTLDesigner: a computational tool for constructing polyepitope T-cell antigens. BMC Res Notes (2013) 0.83
Rapid characterization of candidate biomarkers for pancreatic cancer using cell microarrays (CMAs). J Proteome Res (2012) 0.83
Killer cell immunoglobulin-like receptor gene associations with autoimmune and allergic diseases, recurrent spontaneous abortion, and neoplasms. Front Immunol (2013) 0.83
Deciphering complex patterns of class-I HLA-peptide cross-reactivity via hierarchical grouping. Immunol Cell Biol (2015) 0.83
NLRC5, at the Heart of Antigen Presentation. Front Immunol (2013) 0.83
Immune targets and neoantigens for cancer immunotherapy and precision medicine. Cell Res (2016) 0.83
Differential ion mobility spectrometry coupled to tandem mass spectrometry enables targeted leukemia antigen detection. J Proteome Res (2014) 0.82
Different antigen-processing activities in dendritic cells, macrophages, and monocytes lead to uneven production of HIV epitopes and affect CTL recognition. J Immunol (2014) 0.82
Specificities of human CD4+ T cell responses to an inactivated flavivirus vaccine and infection: correlation with structure and epitope prediction. J Virol (2014) 0.82
An evolutionary analysis of antigen processing and presentation across different timescales reveals pervasive selection. PLoS Genet (2014) 0.82
Autosomal Minor Histocompatibility Antigens: How Genetic Variants Create Diversity in Immune Targets. Front Immunol (2016) 0.82
High major histocompatibility complex class I polymorphism despite bottlenecks in wild and domesticated populations of the zebra finch (Taeniopygia guttata). BMC Evol Biol (2015) 0.82
Genetic variation in MHC proteins is associated with T cell receptor expression biases. Nat Genet (2016) 0.82
Present Yourself! By MHC Class I and MHC Class II Molecules. Trends Immunol (2016) 0.81
Identification and Functional Prediction of Large Intergenic Noncoding RNAs (lincRNAs) in Rainbow Trout (Oncorhynchus mykiss). Mar Biotechnol (NY) (2016) 0.80
Host glycans and antigen presentation. Microbes Infect (2012) 0.80
Alternative Antigen Processing for MHC Class I: Multiple Roads Lead to Rome. Front Immunol (2015) 0.80
Structural Characteristics of HLA-DQ that May Impact DM Editing and Susceptibility to Type-1 Diabetes. Front Immunol (2013) 0.80
Histocompatibility and hematopoietic transplantation in the zebrafish. Adv Hematol (2012) 0.80
Widespread RNA and DNA sequence differences in the human transcriptome. Science (2011) 11.45
Rapid degradation of a large fraction of newly synthesized proteins by proteasomes. Nature (2000) 7.10
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins. Nature (2009) 6.99
Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments. Nature (1991) 5.90
Inflammatory stimuli induce accumulation of MHC class II complexes on dendritic cells. Nature (1997) 5.80
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet (2011) 5.56
Developmental regulation of MHC class II transport in mouse dendritic cells. Nature (1997) 5.17
Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. J Exp Med (2006) 4.84
Immunoproteasomes preserve protein homeostasis upon interferon-induced oxidative stress. Cell (2010) 4.45
The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route. Cell (1990) 4.18
Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function. Nat Rev Mol Cell Biol (2009) 4.16
T-cell engagement of dendritic cells rapidly rearranges MHC class II transport. Nature (2002) 3.93
ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum. Nature (2002) 3.72
AAA+ proteases: ATP-fueled machines of protein destruction. Annu Rev Biochem (2011) 3.60
Defining the role of the MHC in autoimmunity: a review and pooled analysis. PLoS Genet (2008) 3.54
The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues. Nat Immunol (2002) 3.45
Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum. Nat Immunol (2005) 3.39
Activation of lysosomal function during dendritic cell maturation. Science (2003) 3.22
An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides. Nat Immunol (2002) 3.22
Quantitating protein synthesis, degradation, and endogenous antigen processing. Immunity (2003) 3.14
Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk. Nat Immunol (2011) 3.12
Cross-presentation by intercellular peptide transfer through gap junctions. Nature (2005) 3.03
Making sense of mass destruction: quantitating MHC class I antigen presentation. Nat Rev Immunol (2003) 3.00
The known unknowns of antigen processing and presentation. Nat Rev Immunol (2008) 2.85
Immune recognition of a human renal cancer antigen through post-translational protein splicing. Nature (2004) 2.84
The major substrates for TAP in vivo are derived from newly synthesized proteins. Nature (2000) 2.70
Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination. Nature (2006) 2.64
Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins. J Virol (2004) 2.63
In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides. Nat Immunol (2006) 2.62
Protein targeting and degradation are coupled for elimination of mislocalized proteins. Nature (2011) 2.54
A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation. Immunity (2004) 2.53
Cross-priming in health and disease. Nat Rev Immunol (2010) 2.51
Innate immune and chemically triggered oxidative stress modifies translational fidelity. Nature (2009) 2.50
The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a "molecular ruler" mechanism. Proc Natl Acad Sci U S A (2005) 2.47
Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning. J Cell Biol (2009) 2.45
Regulation of MHC class II gene expression by the class II transactivator. Nat Rev Immunol (2005) 2.44
Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome. Proc Natl Acad Sci U S A (1997) 2.39
Differential microRNA regulation of HLA-C expression and its association with HIV control. Nature (2011) 2.36
Bacteria-induced gap junctions in tumors favor antigen cross-presentation and antitumor immunity. Sci Transl Med (2010) 2.32
Modeling the MHC class I pathway by combining predictions of proteasomal cleavage, TAP transport and MHC class I binding. Cell Mol Life Sci (2005) 2.32
Mice lacking the MHC class II-associated invariant chain. Cell (1993) 2.30
Antigen presentation by interferon-gamma-treated endothelial cells and fibroblasts: differential ability to function as antigen-presenting cells despite comparable Ia expression. J Immunol (1985) 2.27
Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression. J Exp Med (1993) 2.27
Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products. J Exp Med (2001) 2.27
An antigenic peptide produced by peptide splicing in the proteasome. Science (2004) 2.20
Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing. Cell (2006) 2.20
Recycling MHC class I molecules and endosomal peptide loading. Proc Natl Acad Sci U S A (1999) 2.17
Protein degradation and the generation of MHC class I-presented peptides. Adv Immunol (2002) 2.17
The CD19/CD21 signal transducing complex of human B lymphocytes includes the target of antiproliferative antibody-1 and Leu-13 molecules. J Immunol (1992) 2.17
MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation. Proc Natl Acad Sci U S A (2008) 2.13
26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide. EMBO J (2001) 2.09
Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments. Science (1994) 2.08
Allele and locus-specific differences in cell surface expression and the association of HLA class I heavy chain with beta 2-microglobulin: differential effects of inhibition of glycosylation on class I subunit association. Eur J Immunol (1988) 2.03
Additive contribution of HLA class I alleles in the immune control of HIV-1 infection. J Virol (2010) 1.97
Interleukin-10 down-regulates MHC class II alphabeta peptide complexes at the plasma membrane of monocytes by affecting arrival and recycling. Immunity (1997) 1.97
The quality control of MHC class I peptide loading. Curr Opin Cell Biol (2008) 1.91
Peptide diffusion, protection, and degradation in nuclear and cytoplasmic compartments before antigen presentation by MHC class I. Immunity (2003) 1.89
Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells. J Cell Biol (2001) 1.87
Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface. J Cell Biol (1996) 1.80
The lysosomal cysteine proteases in MHC class II antigen presentation. Immunol Rev (2005) 1.78
Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells. Nat Immunol (2005) 1.76
Editing of the HLA-DR-peptide repertoire by HLA-DM. EMBO J (1996) 1.74
Generation of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII. Nat Immunol (2004) 1.68
Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape. Immunity (2005) 1.64
Two new proteases in the MHC class I processing pathway. Nat Immunol (2000) 1.63
HLA-B27-restricted antigen presentation in the absence of tapasin reveals polymorphism in mechanisms of HLA class I peptide loading. Immunity (1998) 1.58
MHC class II expression by the gut epithelium. Immunol Today (1988) 1.51
Interleukin-10-induced MARCH1 mediates intracellular sequestration of MHC class II in monocytes. Eur J Immunol (2008) 1.49
Involvement of clathrin and AP-2 in the trafficking of MHC class II molecules to antigen-processing compartments. Proc Natl Acad Sci U S A (2005) 1.47
Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells. J Immunol (2010) 1.46
Cutting edge: neosynthesis is required for the presentation of a T cell epitope from a long-lived viral protein. J Immunol (2001) 1.44
Structural basis for antigenic peptide precursor processing by the endoplasmic reticulum aminopeptidase ERAP1. Nat Struct Mol Biol (2011) 1.42
CD83 increases MHC II and CD86 on dendritic cells by opposing IL-10-driven MARCH1-mediated ubiquitination and degradation. J Exp Med (2011) 1.42
A cytosolic pathway for MHC class II-restricted antigen processing that is proteasome and TAP dependent. Nat Immunol (2005) 1.41
Export of antigenic peptides from the endoplasmic reticulum intersects with retrograde protein translocation through the Sec61p channel. Immunity (2000) 1.41
Regulation of MHC class II expression and antigen processing in murine and human mesenchymal stromal cells by IFN-gamma, TGF-beta, and cell density. J Immunol (2007) 1.41
Major source of antigenic peptides for the MHC class I pathway is produced during the pioneer round of mRNA translation. Proc Natl Acad Sci U S A (2011) 1.40
Efficient internalization of MHC I requires lysine-11 and lysine-63 mixed linkage polyubiquitin chains. Traffic (2009) 1.39
HLA-DM captures partially empty HLA-DR molecules for catalyzed removal of peptide. Nat Immunol (2010) 1.38
The cytosolic endopeptidase, thimet oligopeptidase, destroys antigenic peptides and limits the extent of MHC class I antigen presentation. Immunity (2003) 1.36
Trimming of TAP-translocated peptides in the endoplasmic reticulum and in the cytosol during recycling. J Exp Med (1994) 1.36
The role of the proteasome in the generation of MHC class I ligands and immune responses. Cell Mol Life Sci (2011) 1.35
Reduced cell surface expression of HLA-C molecules correlates with restricted peptide binding and stable TAP interaction. J Immunol (1998) 1.34
Diversity of endogenous epitopes bound to MHC class II molecules limited by invariant chain. Science (1994) 1.32
TCR-induced transmembrane signaling by peptide/MHC class II via associated Ig-alpha/beta dimers. Science (2001) 1.31
Right place, right time, right peptide: DO keeps DM focused. Immunol Rev (2005) 1.30
AP2 clathrin adaptor complex, but not AP1, controls the access of the major histocompatibility complex (MHC) class II to endosomes. J Biol Chem (2005) 1.30
The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation. Immunity (2008) 1.30
The low-affinity receptor for IgE (CD23) on B lymphocytes is spatially associated with HLA-DR antigens. J Exp Med (1988) 1.29
Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells. Immunity (2009) 1.29
Autophagy and adaptive immunity. Immunology (2010) 1.26
The leucine-based sorting motifs in the cytoplasmic domain of the invariant chain are recognized by the clathrin adaptors AP1 and AP2 and their medium chains. J Biol Chem (1999) 1.26
Compartmentalized MHC class I antigen processing enhances immunosurveillance by circumventing the law of mass action. Proc Natl Acad Sci U S A (2010) 1.25
Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes. Nat Immunol (2010) 1.24
Viral evasion of T cell immunity: ancient mechanisms offering new applications. Curr Opin Immunol (2010) 1.24
Calreticulin-dependent recycling in the early secretory pathway mediates optimal peptide loading of MHC class I molecules. EMBO J (2009) 1.23
Differences in the risk of celiac disease associated with HLA-DQ2.5 or HLA-DQ2.2 are related to sustained gluten antigen presentation. Nat Immunol (2009) 1.22
ABC proteins in antigen translocation and viral inhibition. Nat Chem Biol (2010) 1.22
Major histocompatibility complex class I binding predictions as a tool in epitope discovery. Immunology (2010) 1.21
The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes. Immunity (2010) 2.29
Engraftment potential of human amnion and chorion cells derived from term placenta. Transplantation (2004) 2.18
Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling. EMBO J (2006) 1.72
Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA. Mol Cell Biol (2007) 1.70
Major histocompatibility complex class II-peptide complexes internalize using a clathrin- and dynamin-independent endocytosis pathway. J Biol Chem (2008) 1.64
Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling: role of CD14 and CD36. J Leukoc Biol (2008) 1.61
Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments. Blood (2004) 1.50
Invariant chain as a vehicle to load antigenic peptides on human MHC class I for cytotoxic T-cell activation. Eur J Immunol (2013) 1.45
Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5. Histochem Cell Biol (2009) 1.36
The adaptor protein AP-3 is required for CD1d-mediated antigen presentation of glycosphingolipids and development of Valpha14i NKT cells. J Exp Med (2003) 1.31
c-Myb associates with PML in nuclear bodies in hematopoietic cells. Exp Cell Res (2004) 1.27
Ubiquitination regulates MHC class II-peptide complex retention and degradation in dendritic cells. Proc Natl Acad Sci U S A (2010) 1.21
Characterization of a novel chemokine-containing storage granule in endothelial cells: evidence for preferential exocytosis mediated by protein kinase A and diacylglycerol. J Immunol (2005) 1.20
Rab7b controls trafficking from endosomes to the TGN. J Cell Sci (2010) 1.20
A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation. Cell (2011) 1.14
The protein phosphatase 1 regulator PNUTS is a new component of the DNA damage response. EMBO Rep (2010) 1.10
The mouse CD1d cytoplasmic tail mediates CD1d trafficking and antigen presentation by adaptor protein 3-dependent and -independent mechanisms. J Immunol (2005) 1.06
CD56(bright)perforin(low) noncytotoxic human NK cells are abundant in both healthy and neoplastic solid tissues and recirculate to secondary lymphoid organs via afferent lymph. J Immunol (2014) 1.04
Mechanism of interaction between leucine-based sorting signals from the invariant chain and clathrin-associated adaptor protein complexes AP1 and AP2. J Biol Chem (2002) 0.98
Structural requirements for interactions between leucine-sorting signals and clathrin-associated adaptor protein complex AP3. J Biol Chem (2002) 0.98
Cadmium-induced inflammatory responses in cells relevant for lung toxicity: Expression and release of cytokines in fibroblasts, epithelial cells and macrophages. Toxicol Lett (2010) 0.97
Routes to manipulate MHC class II antigen presentation. Curr Opin Immunol (2010) 0.97
The cytoplasmic tail of invariant chain regulates endosome fusion and morphology. Mol Biol Cell (2002) 0.95
Cell-cycle-dependent binding kinetics for the early endosomal tethering factor EEA1. EMBO Rep (2008) 0.95
Uncoating ATPase Hsc70 is recruited by invariant chain and controls the size of endocytic compartments. Proc Natl Acad Sci U S A (2002) 0.94
Generation of potent anti-tumor immunity in mice by interleukin-12-secreting dendritic cells. Cancer Immunol Immunother (2005) 0.93
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking. J Cell Sci (2011) 0.92
The fusion of early endosomes induces molecular-motor-driven tubule formation and fission. J Cell Sci (2012) 0.90
Semi-mature IL-12 secreting dendritic cells present exogenous antigen to trigger cytolytic immune responses. Cancer Immunol Immunother (2005) 0.89
Dynamics of Rab7b-dependent transport of sorting receptors. Traffic (2012) 0.88
Re-routing of the invariant chain to the direct sorting pathway by introduction of an AP3-binding motif from LIMP II. Eur J Cell Biol (2006) 0.86
Dynamics within tetraspanin pairs affect MHC class II expression. J Cell Sci (2012) 0.85
Rab7b and receptors trafficking. Commun Integr Biol (2010) 0.83
CD40 ligation restores type 1 polarizing capacity in TLR4-activated dendritic cells that have ceased interleukin-12 expression. J Cell Mol Med (2009) 0.83
Human PARM-1 is a novel mucin-like, androgen-regulated gene exhibiting proliferative effects in prostate cancer cells. Int J Cancer (2008) 0.83
Charcot-Marie-Tooth disease and intracellular traffic. Prog Neurobiol (2012) 0.81
The cytoplasmic tail of invariant chain modulates antigen processing and presentation. Eur J Immunol (2003) 0.81
BiP negatively affects ricin transport. Toxins (Basel) (2013) 0.80
Invariant chain increases the half-life of MHC II by delaying endosomal maturation. Immunol Cell Biol (2010) 0.80
The adaptor protein AP-4 as a component of the clathrin coat machinery: a morphological study. Biochem J (2005) 0.79
Differential regulation of Rab GTPase expression in monocyte-derived dendritic cells upon lipopolysaccharide activation: a correlation to maturation-dependent functional properties. PLoS One (2013) 0.79
MHC class II loading of high or low affinity peptides directed by Ii/peptide fusion constructs: implications for T cell activation. Int Immunol (2003) 0.78
Differential regulation of MHC II and invariant chain expression during maturation of monocyte-derived dendritic cells. J Leukoc Biol (2012) 0.78
Human NCU-G1 can function as a transcription factor and as a nuclear receptor co-activator. BMC Mol Biol (2007) 0.77
Exploring genome-wide datasets of MHC class II antigen presentation. Mol Immunol (2012) 0.76
B-cell tolerance to the B-cell receptor variable regions. Eur J Immunol (2013) 0.75
Characterization of the role of RILP in cell migration. Eur J Histochem (2017) 0.75