Published in Cell on July 14, 2016
2016 Presidential Address: Let's Make Human Genetics Great (Again): The Importance of Beauty in Science. Am J Hum Genet (2017) 0.75
From Peas to Disease: Modifier Genes, Network Resilience, and the Genetics of Health. Am J Hum Genet (2017) 0.75
Finding the missing heritability of complex diseases. Nature (2009) 67.95
Prediction of total genetic value using genome-wide dense marker maps. Genetics (2001) 41.25
The mystery of missing heritability: Genetic interactions create phantom heritability. Proc Natl Acad Sci U S A (2012) 11.23
Invited review: Genomic selection in dairy cattle: progress and challenges. J Dairy Sci (2009) 9.76
Estimating missing heritability for disease from genome-wide association studies. Am J Hum Genet (2011) 8.95
The Drosophila melanogaster Genetic Reference Panel. Nature (2012) 7.94
Data and theory point to mainly additive genetic variance for complex traits. PLoS Genet (2008) 7.15
Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet (2014) 5.78
Epistasis and its contribution to genetic variance components. Genetics (1995) 4.99
Predicting genetic predisposition in humans: the promise of whole-genome markers. Nat Rev Genet (2010) 3.59
Finding the sources of missing heritability in a yeast cross. Nature (2013) 3.43
Pitfalls of predicting complex traits from SNPs. Nat Rev Genet (2013) 3.06
Order of action of components in the yeast pheromone response pathway revealed with a dominant allele of the STE11 kinase and the multiple phosphorylation of the STE7 kinase. Genes Dev (1992) 2.85
Epistasis analysis with global transcriptional phenotypes. Nat Genet (2005) 2.67
Epistasis dominates the genetic architecture of Drosophila quantitative traits. Proc Natl Acad Sci U S A (2012) 2.59
Has the revolution arrived? Nature (2010) 2.47
Meta-analysis of the heritability of human traits based on fifty years of twin studies. Nat Genet (2015) 2.34
Detection and replication of epistasis influencing transcription in humans. Nature (2014) 1.95
Characterizing genetic interactions in human disease association studies using statistical epistasis networks. BMC Bioinformatics (2011) 1.68
Detecting epistasis in human complex traits. Nat Rev Genet (2014) 1.61
Measuring missing heritability: inferring the contribution of common variants. Proc Natl Acad Sci U S A (2014) 1.58
Microbial evolution. Global epistasis makes adaptation predictable despite sequence-level stochasticity. Science (2014) 1.57
Should evolutionary geneticists worry about higher-order epistasis? Curr Opin Genet Dev (2013) 1.52
Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index. Nat Genet (2015) 1.51
Another explanation for apparent epistasis. Nature (2014) 1.35
An evolutionary perspective on epistasis and the missing heritability. PLoS Genet (2013) 1.33
Influence of gene interaction on complex trait variation with multilocus models. Genetics (2014) 1.31
Ubiquitous polygenicity of human complex traits: genome-wide analysis of 49 traits in Koreans. PLoS Genet (2013) 1.29
Genetic incompatibilities are widespread within species. Nature (2013) 1.28
Tandem repeat polymorphisms: modulators of disease susceptibility and candidates for 'missing heritability'. Trends Genet (2009) 1.27
Genomic selection: genome-wide prediction in plant improvement. Trends Plant Sci (2014) 1.19
Genomic consequences of background effects on scalloped mutant expressivity in the wing of Drosophila melanogaster. Genetics (2008) 1.15
Dominance genetic variation contributes little to the missing heritability for human complex traits. Am J Hum Genet (2015) 1.14
Phenogram enumeration: the number of regular genotype-phenotype correspondences in genetic systems. J Theor Biol (1968) 1.09
Explaining additional genetic variation in complex traits. Trends Genet (2014) 1.08
Correction for Krishna Kumar et al., Limitations of GCTA as a solution to the missing heritability problem. Proc Natl Acad Sci U S A (2016) 1.08
The Caenorhabditis elegans vulva: a post-embryonic gene regulatory network controlling organogenesis. Proc Natl Acad Sci U S A (2008) 0.99
Epigenetic inheritance and the missing heritability. Hum Genomics (2015) 0.95
Natural Variation in Gene Expression Modulates the Severity of Mutant Phenotypes. Cell (2015) 0.94
Extensive epistasis for olfactory behaviour, sleep and waking activity in Drosophila melanogaster. Genet Res (Camb) (2012) 0.88
Candidate genetic modifiers of retinitis pigmentosa identified by exploiting natural variation in Drosophila. Hum Mol Genet (2015) 0.87
Morphogenesis of the vulva and the vulval-uterine connection. WormBook (2012) 0.87
Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin. Genetics (2013) 0.85
Predicting epistasis from mathematical models. Evol Comput (1999) 0.84
Estimation of epistatic variance components and heritability in founder populations and crosses. Genetics (2014) 0.84
What can we learn from fitness landscapes? Curr Opin Microbiol (2014) 0.83
Meta-analysis of SNPs involved in variance heterogeneity using Levene's test for equal variances. Eur J Hum Genet (2013) 0.81