Published in J Biol Chem on July 20, 2016
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Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis. Mol Cell (2003) 5.66
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IQGAP1 integrates Ca2+/calmodulin and Cdc42 signaling. J Biol Chem (1999) 1.72
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Two distinct myosin light chain structures are induced by specific variations within the bound IQ motifs-functional implications. EMBO J (2003) 1.40
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Elucidation of the interaction of calmodulin with the IQ motifs of IQGAP1. J Biol Chem (2002) 1.27
IQGAP3, a novel effector of Rac1 and Cdc42, regulates neurite outgrowth. J Cell Sci (2007) 1.24
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Bile acids activate YAP to promote liver carcinogenesis. Cell Rep (2013) 1.14
IQGAP1 promotes neurite outgrowth in a phosphorylation-dependent manner. J Biol Chem (2005) 1.13
MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation. J Biol Chem (2011) 1.09
Self-association of IQGAP1: characterization and functional sequelae. J Biol Chem (2005) 1.09
The zinc- and calcium-binding S100B interacts and co-localizes with IQGAP1 during dynamic rearrangement of cell membranes. J Biol Chem (2002) 1.09
IQGAP1 suppresses TβRII-mediated myofibroblastic activation and metastatic growth in liver. J Clin Invest (2013) 1.06
IQGAP1 regulates ERK1/2 and AKT signalling in the heart and sustains functional remodelling upon pressure overload. Cardiovasc Res (2011) 1.04
IQGAPs choreograph cellular signaling from the membrane to the nucleus. Trends Cell Biol (2015) 1.02
A novel role for microRNA-129-5p in inhibiting ovarian cancer cell proliferation and survival via direct suppression of transcriptional co-activators YAP and TAZ. Oncotarget (2015) 1.00
IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma. BMC Gastroenterol (2010) 0.98
The biology of IQGAP proteins: beyond the cytoskeleton. EMBO Rep (2015) 0.97
IQGAP1 protein binds human epidermal growth factor receptor 2 (HER2) and modulates trastuzumab resistance. J Biol Chem (2011) 0.96
IQGAP1 translocates to the nucleus in early S-phase and contributes to cell cycle progression after DNA replication arrest. Int J Biochem Cell Biol (2010) 0.95
Identification and functional studies of a new Nrf2 partner IQGAP1: a critical role in the stability and transactivation of Nrf2. Antioxid Redox Signal (2012) 0.88
IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signaling. J Biol Chem (2013) 0.87
IQGAP1 binds to estrogen receptor-α and modulates its function. J Biol Chem (2014) 0.86
IQGAPs as Key Regulators of Actin-cytoskeleton Dynamics. Cell Struct Funct (2015) 0.83
Absence of IQGAP1 leads to insulin resistance. J Biol Chem (2017) 0.75
Calmodulin Lobes Facilitate Dimerization and Activation of Estrogen Receptor-α. J Biol Chem (2017) 0.75