PubRank

Padraic G Fallon

Author PubWeight™ 101.28‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 2010 10.34
2 Transcription factor RORα is critical for nuocyte development. Nat Immunol 2012 3.72
3 The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis. Gastroenterology 2007 2.87
4 Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model. J Allergy Clin Immunol 2010 2.15
5 A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis. J Exp Med 2013 2.11
6 IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration. Sci Transl Med 2014 2.11
7 The alarmin interleukin-33 drives protective antiviral CD8⁺ T cell responses. Science 2012 2.10
8 Infection with a helminth parasite prevents experimental colitis via a macrophage-mediated mechanism. J Immunol 2007 2.09
9 Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice. Gut 2012 1.97
10 Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages. J Immunol 2004 1.91
11 SIGN-R1 contributes to protection against lethal pneumococcal infection in mice. J Exp Med 2004 1.73
12 Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function. Gastroenterology 2010 1.64
13 Helminth infection protects mice from anaphylaxis via IL-10-producing B cells. J Immunol 2004 1.57
14 T1/ST2 expression on Th2 cells negatively regulates allergic pulmonary inflammation. Eur J Immunol 2007 1.50
15 Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells. J Immunol 2011 1.47
16 Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment. J Cell Biol 2010 1.40
17 A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins. PLoS Pathog 2011 1.39
18 Cutting edge: IL-25 elicits innate lymphoid type 2 and type II NKT cells that regulate obesity in mice. J Immunol 2013 1.38
19 The schistosoma granuloma: friend or foe? Front Immunol 2013 1.34
20 Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects. J Allergy Clin Immunol 2013 1.30
21 Lethal, neonatal ichthyosis with increased proteolytic processing of filaggrin in a mouse model of Netherton syndrome. Hum Mol Genet 2004 1.30
22 Tim-1 is induced on germinal centre B cells through B-cell receptor signalling but is not essential for the germinal centre response. Immunology 2010 1.24
23 Helminth-modified pulmonary immune response protects mice from allergen-induced airway hyperresponsiveness. J Immunol 2006 1.21
24 Mast cells as sensors of cell injury through IL-33 recognition. J Immunol 2011 1.21
25 An intact canonical NF-κB pathway is required for inflammatory gene expression in response to hypoxia. J Immunol 2010 1.20
26 The Toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2013 1.17
27 Th2 activities induced during virgin T cell priming in the absence of IL-4, IL-13, and B cells. J Immunol 2002 1.16
28 IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis. Proc Natl Acad Sci U S A 2013 1.16
29 Schistosoma mansoni secretes a chemokine binding protein with antiinflammatory activity. J Exp Med 2005 1.13
30 Upregulation of retinal dehydrogenase 2 in alternatively activated macrophages during retinoid-dependent type-2 immunity to helminth infection in mice. PLoS Pathog 2012 1.13
31 Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus. J Allergy Clin Immunol 2010 1.12
32 IL-33 shifts the balance from osteoclast to alternatively activated macrophage differentiation and protects from TNF-alpha-mediated bone loss. J Immunol 2011 1.12
33 Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction. J Biol Chem 2002 1.12
34 Retracted Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization. Immunity 2012 1.12
35 Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways. Proc Natl Acad Sci U S A 2013 1.12
36 Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency. J Allergy Clin Immunol 2012 1.07
37 Inhibition of type 1 cytokine-mediated inflammation by a soluble CD30 homologue encoded by ectromelia (mousepox) virus. J Exp Med 2002 1.05
38 SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses. J Exp Med 2011 1.01
39 Intraperitoneal influx of neutrophils in response to IL-33 is mast cell-dependent. Blood 2012 0.96
40 C-type lectin SIGN-R1 has a role in experimental colitis and responsiveness to lipopolysaccharide. J Immunol 2010 0.95
41 Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesviruses. PLoS Pathog 2012 0.94
42 Soluble IL-2Rα (sCD25) exacerbates autoimmunity and enhances the development of Th17 responses in mice. PLoS One 2012 0.94
43 Helminth therapies: translating the unknown unknowns to known knowns. Int J Parasitol 2013 0.94
44 Participation of MyD88 and interleukin-33 as innate drivers of Th2 immunity to Trichinella spiralis. Infect Immun 2013 0.93
45 Reduced expression of epidermal growth factor receptor, E-cadherin, and occludin in the skin of flaky tail mice is due to filaggrin and loricrin deficiencies. Am J Pathol 2012 0.93
46 The hydroxylase inhibitor dimethyloxallyl glycine attenuates endotoxic shock via alternative activation of macrophages and IL-10 production by B1 cells. Shock 2011 0.93
47 Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis. Aging Cell 2014 0.92
48 Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis. Nat Immunol 2013 0.92
49 Identification of the synthetic cannabinoid R(+)WIN55,212-2 as a novel regulator of IFN regulatory factor 3 activation and IFN-beta expression: relevance to therapeutic effects in models of multiple sclerosis. J Biol Chem 2011 0.92
50 Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-β signaling. J Biol Chem 2012 0.91
51 Partial redundancy of the pattern recognition receptors, scavenger receptors, and C-type lectins for the long-term control of Mycobacterium tuberculosis infection. J Immunol 2010 0.90
52 Innate type 2 cells and asthma. Curr Opin Pharmacol 2012 0.89
53 Lipid rafts are disrupted in mildly inflamed intestinal microenvironments without overt disruption of the epithelial barrier. Am J Physiol Gastrointest Liver Physiol 2012 0.88
54 The C-type lectin SIGNR1 binds Schistosoma mansoni antigens in vitro, but SIGNR1-deficient mice have normal responses during schistosome infection. Infect Immun 2008 0.88
55 Decoy receptors in the regulation of T helper cell type 2 responses. J Exp Med 2003 0.87
56 Identification of a functioning mitochondrial uncoupling protein 1 in thymus. J Biol Chem 2005 0.86
57 T helper type-2 cytokine responses: potential therapeutic targets. Curr Opin Pharmacol 2003 0.86
58 Orphan receptor IL-17RD tunes IL-17A signalling and is required for neutrophilia. Nat Commun 2012 0.86
59 Hypoxia-dependent regulation of inflammatory pathways in immune cells. J Clin Invest 2016 0.86
60 Previous infection with the nematode Nippostrongylus brasiliensis alters the immune specific response against Chlamydophila abortus infection. Microb Pathog 2002 0.85
61 Effects of Lactobacillus salivarius 433118 on intestinal inflammation, immunity status and in vitro colon function in two mouse models of inflammatory bowel disease. Dig Dis Sci 2007 0.85
62 Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2. J Immunol 2013 0.85
63 Activation of human invariant natural killer T cells with a thioglycoside analogue of α-galactosylceramide. Clin Immunol 2011 0.84
64 Specific intracellular adhesion molecule-grabbing nonintegrin R1 is not involved in the murine antibody response to pneumococcal polysaccharides. Infect Immun 2007 0.84
65 Ursodeoxycholic acid attenuates colonic epithelial secretory function. J Physiol 2013 0.83
66 Cutting edge: suppression of GM-CSF expression in murine and human T cells by IL-27. J Immunol 2012 0.83
67 Lymphomagenesis, hydronephrosis, and autoantibodies result from dysregulation of IL-9 and are differentially dependent on Th2 cytokines. J Immunol 2004 0.83
68 Generation of parasite antigens for use in Toll-like receptor research. Methods Mol Biol 2009 0.83
69 Farnesoid X receptor agonists attenuate colonic epithelial secretory function and prevent experimental diarrhoea in vivo. Gut 2013 0.82
70 Protamine sulfate down-regulates thrombin generation by inhibiting factor V activation. Blood 2009 0.82
71 Mitochondrial uncoupling protein 1 expression in thymocytes. Biochim Biophys Acta 2008 0.81
72 Helminth-derived immunomodulatory molecules. Adv Exp Med Biol 2009 0.80
73 MyD88 adaptor-like (Mal) regulates intestinal homeostasis and colitis-associated colorectal cancer in mice. Am J Physiol Gastrointest Liver Physiol 2014 0.80
74 Hydroxylase inhibition attenuates colonic epithelial secretory function and ameliorates experimental diarrhea. FASEB J 2010 0.79
75 Toll IL-1R8/single Ig IL-1-related receptor regulates psoriasiform inflammation through direct inhibition of innate IL-17A expression by γδ T cells. J Immunol 2013 0.79
76 Impaired basophil induction leads to an age-dependent innate defect in type 2 immunity during helminth infection in mice. J Immunol 2011 0.78
77 The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-β expression via peroxisome proliferator-activated receptor-α. J Biol Chem 2012 0.78
78 Activated factor X signaling via protease-activated receptor 2 suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells. Haematologica 2013 0.78
79 Why does work on same mouse models give different results? Nature 2008 0.77
80 The generation of regulatory B cells by helminth parasites. Methods Mol Biol 2014 0.76
81 A mineral extract from red algae ameliorates chronic spontaneous colitis in IL-10 deficient mice in a mouse strain dependent manner. Phytother Res 2013 0.75
82 The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-β expression via peroxisome proliferator-activated receptor-α. J Biol Chem 2016 0.75
83 Pathogen-derived immunomodulatory molecules. Preface. Adv Exp Med Biol 2009 0.75
84 Design, synthesis, and pharmacological effects of a cyclization-activated steroid prodrug for colon targeting in inflammatory bowel disease. J Med Chem 2009 0.75
85 Juvenile rhesus monkeys have more colonic granulomas than adults after primary infection with Schistosoma mansoni. Virchows Arch 2004 0.75