Published in Cell on August 11, 1989
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Complex proteolytic processing acts on Delta, a transmembrane ligand for Notch, during Drosophila development. Mol Biol Cell (1998) 1.33
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The Drosophila neuralized gene encodes a C3HC4 zinc finger. EMBO J (1993) 1.11
A gene for a low density lipoprotein receptor-related protein in the nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A (1993) 1.10
Identification and characterization of genes that interact with lin-12 in Caenorhabditis elegans. Genetics (1997) 1.09
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Proteasomal regulation of the proliferation vs. meiotic entry decision in the Caenorhabditis elegans germ line. Genetics (2008) 0.89
Reciprocal Changes in Phosphoenolpyruvate Carboxykinase and Pyruvate Kinase with Age Are a Determinant of Aging in Caenorhabditis elegans. J Biol Chem (2015) 0.87
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Characterization of Chlamydomonas reinhardtii zygote-specific cDNAs that encode novel proteins containing ankyrin repeats and WW domains. Plant Physiol (1999) 0.87
Myeloid translocation gene 16 (MTG16) interacts with Notch transcription complex components to integrate Notch signaling in hematopoietic cell fate specification. Mol Cell Biol (2010) 0.87
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TEG-1 CD2BP2 regulates stem cell proliferation and sex determination in the C. elegans germ line and physically interacts with the UAF-1 U2AF65 splicing factor. Dev Dyn (2012) 0.82
Two classes of gap junction channels mediate soma-germline interactions essential for germline proliferation and gametogenesis in Caenorhabditis elegans. Genetics (2014) 0.82
PUF-8, a Pumilio homolog, inhibits the proliferative fate in the Caenorhabditis elegans germline. G3 (Bethesda) (2012) 0.81
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Reciprocal signaling by Wnt and Notch specifies a muscle precursor in the C. elegans embryo. Development (2017) 0.75
Influences of LIN-12/Notch and POP-1/TCF on the Robustness of Ventral Uterine Cell Fate Specification in Caenorhabditis elegans Gonadogenesis. G3 (Bethesda) (2015) 0.75
Intricate and Cell-type-specific Populations of Endogenous Circular DNA (eccDNA) in Caenorhabditis elegans and Homo sapiens. G3 (Bethesda) (2017) 0.75
Presenilin is required for activity and nuclear access of Notch in Drosophila. Nature (1999) 4.64
Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo. Cell (1993) 3.53
Facilitation of lin-12-mediated signalling by sel-12, a Caenorhabditis elegans S182 Alzheimer's disease gene. Nature (1995) 3.33
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Genetic analysis of endocytosis in Caenorhabditis elegans: coelomocyte uptake defective mutants. Genetics (2001) 2.35
The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch. Nature (1988) 2.27
Regulation of endocytosis by CUP-5, the Caenorhabditis elegans mucolipin-1 homolog. Nat Genet (2001) 2.23
sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins. Genes Dev (1997) 2.17
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A C. elegans E/Daughterless bHLH protein marks neuronal but not striated muscle development. Development (1997) 1.81
SUP-17, a Caenorhabditis elegans ADAM protein related to Drosophila KUZBANIAN, and its role in LIN-12/NOTCH signalling. Development (1997) 1.80
Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision. Cell (1994) 1.79
Presenilin-mediated transmembrane cleavage is required for Notch signal transduction in Drosophila. Proc Natl Acad Sci U S A (2001) 1.74
The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway. Genes Dev (1995) 1.66
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Suppressors of a lin-12 hypomorph define genes that interact with both lin-12 and glp-1 in Caenorhabditis elegans. Genetics (1993) 1.58
HOP-1, a Caenorhabditis elegans presenilin, appears to be functionally redundant with SEL-12 presenilin and to facilitate LIN-12 and GLP-1 signaling. Proc Natl Acad Sci U S A (1997) 1.55
Interchangeability of Caenorhabditis elegans DSL proteins and intrinsic signalling activity of their extracellular domains in vivo. Development (1995) 1.52
A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting. Development (1999) 1.49
p24 proteins and quality control of LIN-12 and GLP-1 trafficking in Caenorhabditis elegans. J Cell Biol (1999) 1.43
Correlation of the physical and genetic maps in the lin-12 region of Caenorhabditis elegans. Nucleic Acids Res (1987) 1.40
Membrane topology of the C. elegans SEL-12 presenilin. Neuron (1996) 1.38
glp-1 can substitute for lin-12 in specifying cell fate decisions in Caenorhabditis elegans. Development (1993) 1.34
The Caenorhabditis elegans sel-1 gene, a negative regulator of lin-12 and glp-1, encodes a predicted extracellular protein. Genetics (1996) 1.33
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Isolation and characterization of mutations causing abnormal eversion of the vulva in Caenorhabditis elegans. Dev Biol (1993) 1.26
Genetic and phenotypic studies of hypomorphic lin-12 mutants in Caenorhabditis elegans. Genetics (1993) 1.24
A visible allele of the muscle gene sup-10X of C. elegans. Genetics (1986) 1.20
Additional evidence for an eight-transmembrane-domain topology for Caenorhabditis elegans and human presenilins. Proc Natl Acad Sci U S A (1998) 1.17
Effects of SEL-12 presenilin on LIN-12 localization and function in Caenorhabditis elegans. Development (1998) 1.11
lin-25, a gene required for vulval induction in Caenorhabditis elegans. Genes Dev (1995) 1.10
A gene for a low density lipoprotein receptor-related protein in the nematode Caenorhabditis elegans. Proc Natl Acad Sci U S A (1993) 1.10
Structure, function, and expression of SEL-1, a negative regulator of LIN-12 and GLP-1 in C. elegans. Development (1997) 1.10
Evidence for functional and physical association between Caenorhabditis elegans SEL-10, a Cdc4p-related protein, and SEL-12 presenilin. Proc Natl Acad Sci U S A (1998) 1.08
Caenorhabditis elegans lin-13, a member of the LIN-35 Rb class of genes involved in vulval development, encodes a protein with zinc fingers and an LXCXE motif. Genetics (2000) 1.08
SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans. Proc Natl Acad Sci U S A (2000) 1.07
Evidence for physical and functional association between EMB-5 and LIN-12 in Caenorhabditis elegans. Science (1996) 1.04
LIN-12 protein expression and localization during vulval development in C. elegans. Development (1998) 1.03
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Cardiac arrest and the role of thrombolytic agents. Ann Emerg Med (2000) 0.95
Two novel transmembrane protein tyrosine kinases expressed during Caenorhabditis elegans hypodermal development. Mol Cell Biol (1993) 0.93
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Spatial and temporal patterns of lin-12 expression during C. elegans hermaphrodite development. Genetics (1995) 0.91
SEL-5, a serine/threonine kinase that facilitates lin-12 activity in Caenorhabditis elegans. Genetics (1999) 0.90
A Caenorhabditis elegans cDNA that encodes a product resembling the rat glutathione S-transferase P subunit. Nucleic Acids Res (1989) 0.88
Caenorhabditis elegans lin-25: cellular focus, protein expression and requirement for sur-2 during induction of vulval fates. Development (1998) 0.81
The lin-12 locus of Caenorhabditis elegans. Bioessays (1987) 0.75
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