Published in Genes (Basel) on September 01, 2016
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Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival. Proc Natl Acad Sci U S A (2001) 1.83
Cellular aging reflected by leukocyte telomere length predicts advanced atherosclerosis and cardiovascular disease risk. Arterioscler Thromb Vasc Biol (2010) 1.81
Genome-wide meta-analysis points to CTC1 and ZNF676 as genes regulating telomere homeostasis in humans. Hum Mol Genet (2012) 1.77
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice. Nat Commun (2014) 1.72
Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease. JAMA (2010) 1.71
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer. EMBO Mol Med (2012) 1.66
Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation. EMBO J (2003) 1.66
Leukocyte telomere length and carotid artery intimal medial thickness: the Framingham Heart Study. Arterioscler Thromb Vasc Biol (2008) 1.64
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Physical exercise prevents cellular senescence in circulating leukocytes and in the vessel wall. Circulation (2009) 1.63
Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection. Science (2015) 1.59
Pioglitazone activates aortic telomerase and prevents stress-induced endothelial apoptosis. Atherosclerosis (2011) 1.56
Association between oxidative DNA damage and telomere shortening in circulating endothelial progenitor cells obtained from metabolic syndrome patients with coronary artery disease. Atherosclerosis (2007) 1.55
Multivitamin use and telomere length in women. Am J Clin Nutr (2009) 1.54
Telomere length in old age and cholesterol across the life course. J Am Geriatr Soc (2011) 1.50
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Endothelial progenitor cells in the natural history of atherosclerosis. Atherosclerosis (2007) 1.44
Constitutive human telomerase reverse transcriptase expression enhances regenerative properties of endothelial progenitor cells. Circulation (2002) 1.43
Effects of physical exercise on myocardial telomere-regulating proteins, survival pathways, and apoptosis. J Am Coll Cardiol (2008) 1.43
The relative lengths of individual telomeres are defined in the zygote and strictly maintained during life. Aging Cell (2004) 1.42
Accelerated telomere shortening in leukocyte subpopulations of patients with coronary heart disease: role of cytomegalovirus seropositivity. Circulation (2009) 1.41
Comparison of chromosome telomere integrity in multiple tissues from subjects at different ages. Cancer Genet Cytogenet (1998) 1.39
Telomere attrition and Chk2 activation in human heart failure. Proc Natl Acad Sci U S A (2003) 1.37
Telomere attrition of the human abdominal aorta: relationships with age and atherosclerosis. Atherosclerosis (2000) 1.37
Increased vascular senescence and impaired endothelial progenitor cell function mediated by mutation of circadian gene Per2. Circulation (2008) 1.36
Vascular smooth muscle cell senescence in atherosclerosis. Cardiovasc Res (2006) 1.36
Role of CD8 T Cell Replicative Senescence in Human Aging and in HIV-mediated Immunosenescence. Aging Dis (2011) 1.33
Nitric oxide activates telomerase and delays endothelial cell senescence. Circ Res (2000) 1.29
Diastolic heart failure--a common and lethal condition by any name. N Engl J Med (2006) 1.27
Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells. Circulation (2004) 1.25
Cytomegalovirus infection is associated with increased mortality in the older population. Aging Cell (2013) 1.23
Immunosenescence and immunogenetics of human longevity. Neuroimmunomodulation (2008) 1.19
Telomere length is shorter in healthy offspring of subjects with coronary artery disease: support for the telomere hypothesis. Heart (2008) 1.16
Angiotensin II-mediated oxidative DNA damage accelerates cellular senescence in cultured human vascular smooth muscle cells via telomere-dependent and independent pathways. Circ Res (2007) 1.16
Association of telomere length in older men with mortality and midlife body mass index and smoking. J Gerontol A Biol Sci Med Sci (2011) 1.14
Shared environmental factors associated with telomere length maintenance in elderly male twins. Aging Cell (2007) 1.14
Telomere length is associated with left ventricular function in the oldest old: the Newcastle 85+ study. Eur Heart J (2007) 1.14
Antagonistic effects of telomerase on cancer and aging in K5-mTert transgenic mice. Oncogene (2005) 1.12
Medicine. Cardiac regeneration. Science (2012) 1.10
Body mass index and leukocyte telomere length in adults: a systematic review and meta-analysis. Obes Rev (2013) 1.10
Mechanisms of telomerase induction during vascular smooth muscle cell proliferation. Circ Res (2001) 1.06
Fibroblast growth factor-2, but not vascular endothelial growth factor, upregulates telomerase activity in human endothelial cells. Arterioscler Thromb Vasc Biol (2003) 1.06
Pro-atherogenic factors induce telomerase inactivation in endothelial cells through an Akt-dependent mechanism. FEBS Lett (2001) 1.04
The relationship between serum markers of collagen turnover and cardiovascular outcome in the elderly: the Cardiovascular Health Study. Circ Heart Fail (2011) 0.99
Reduced number and function of endothelial progenitor cells in patients with aortic valve stenosis: a novel concept for valvular endothelial cell repair. Eur Heart J (2008) 0.97
Ethanol-induced oxidative stress: basic knowledge. Genes Nutr (2009) 0.97
Circulating leukocyte and carotid atherosclerotic plaque telomere length: interrelation, association with plaque characteristics, and restenosis after endarterectomy. Arterioscler Thromb Vasc Biol (2011) 0.95
Short telomeres protect from diet-induced atherosclerosis in apolipoprotein E-null mice. FASEB J (2003) 0.95
Telomere-associated polymorphisms correlate with cardiovascular disease mortality in Caucasian women: the Cardiovascular Health Study. Mech Ageing Dev (2012) 0.92
Leukocyte Telomere Length and Risks of Incident Coronary Heart Disease and Mortality in a Racially Diverse Population of Postmenopausal Women. Arterioscler Thromb Vasc Biol (2015) 0.89
Genomic imbalances in key ion channel genes and telomere shortening in sudden cardiac death victims. Cytogenet Genome Res (2009) 0.89
Leukocyte telomere length is associated with high-risk plaques on virtual histology intravascular ultrasound and increased proinflammatory activity. Arterioscler Thromb Vasc Biol (2011) 0.89