Telomere length as an indicator of biological aging: the gender effect and relation with pulse pressure and pulse wave velocity.

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Published in Hypertension on February 01, 2001

Authors

A Benetos1, K Okuda, M Lajemi, M Kimura, F Thomas, J Skurnick, C Labat, K Bean, A Aviv

Author Affiliations

1: Center "Investigations Preventives et Cliniques" , INSERM U337, Paris, France. benetos@ipc.asso.fr

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A simple method for estimating evolutionary rates of base substitutions through comparative studies of nucleotide sequences. J Mol Evol (1980) 113.75

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A model of mutation appropriate to estimate the number of electrophoretically detectable alleles in a finite population. Genet Res (1973) 13.08

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Orthotopic liver transplantation in dogs receiving FK-506. Transplant Proc (1987) 3.11

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Mutation and evolution at the molecular level. Genetics (1973) 2.79

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Possibility of extensive neutral evolution under stabilizing selection with special reference to nonrandom usage of synonymous codons. Proc Natl Acad Sci U S A (1981) 2.23

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Molecular clock of viral evolution, and the neutral theory. Proc Natl Acad Sci U S A (1990) 2.15

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The length of time required for a selectively neutral mutant to reach fixation through random frequency drift in a finite population. Genet Res (1970) 2.05

A gene-counting method of maximum likelihood for estimating gene frequencies in ABO and ABO-like systems. Ann Hum Genet (1968) 2.05

Efficiency of truncation selection. Proc Natl Acad Sci U S A (1979) 2.00

Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line. Exp Hematol (1993) 1.98

Selective constraint in protein polymorphism: study of the effectively neutral mutation model by using an improved pseudosampling method. Proc Natl Acad Sci U S A (1983) 1.98

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Behavior of neutral mutants influenced by asociated overdominant loci in finite populations. Genetics (1971) 1.68

Drug-sensitivity of El Tor vibrio strains isolated in the Philippines in 1964 and 1965. Bull World Health Organ (1967) 1.67

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