Published in Biophys J on September 06, 2016
Intrinsically unstructured proteins and their functions. Nat Rev Mol Cell Biol (2005) 17.63
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science (1996) 9.48
The general transcription factors of RNA polymerase II. Genes Dev (1996) 7.15
The role of general initiation factors in transcription by RNA polymerase II. Trends Biochem Sci (1996) 7.00
Mechanism of coupled folding and binding of an intrinsically disordered protein. Nature (2007) 6.26
Solution structure of the KIX domain of CBP bound to the transactivation domain of CREB: a model for activator:coactivator interactions. Cell (1997) 5.39
Slow dynamics in folded and unfolded states of an SH3 domain. J Am Chem Soc (2001) 3.14
Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response. Proc Natl Acad Sci U S A (2002) 2.97
Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators. Nature (2002) 2.78
Oncogenic mutations counteract intrinsic disorder in the EGFR kinase and promote receptor dimerization. Cell (2012) 2.67
Single-stranded DNA mimicry in the p53 transactivation domain interaction with replication protein A. Proc Natl Acad Sci U S A (2005) 2.59
SHIFTX2: significantly improved protein chemical shift prediction. J Biomol NMR (2011) 2.47
Structure and functional properties of human general transcription factor IIE. Nature (1991) 2.45
Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1. J Mol Biol (2008) 1.94
Structure of the Tfb1/p53 complex: Insights into the interaction between the p62/Tfb1 subunit of TFIIH and the activation domain of p53. Mol Cell (2006) 1.82
Structural motifs and potential sigma homologies in the large subunit of human general transcription factor TFIIE. Nature (1991) 1.79
Structural basis for cooperative transcription factor binding to the CBP coactivator. J Mol Biol (2005) 1.75
Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain. Cell Cycle (2008) 1.71
TFIIH: when transcription met DNA repair. Nat Rev Mol Cell Biol (2012) 1.63
Conserved sequence motifs in the small subunit of human general transcription factor TFIIE. Nature (1991) 1.61
A history of TFIIH: two decades of molecular biology on a pivotal transcription/repair factor. DNA Repair (Amst) (2011) 1.52
Unusual biophysics of intrinsically disordered proteins. Biochim Biophys Acta (2012) 1.48
Factors involved in specific transcription by mammalian RNA polymerase II: purification and characterization of general transcription factor TFIIE. Proc Natl Acad Sci U S A (1990) 1.34
Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation. Structure (2009) 1.28
Quantitative analysis of multisite protein-ligand interactions by NMR: binding of intrinsically disordered p53 transactivation subdomains with the TAZ2 domain of CBP. J Am Chem Soc (2012) 1.22
Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein. Biochemistry (2010) 1.21
Structural insight into the TFIIE-TFIIH interaction: TFIIE and p53 share the binding region on TFIIH. EMBO J (2008) 1.17
A free-energy landscape for coupled folding and binding of an intrinsically disordered protein in explicit solvent from detailed all-atom computations. J Am Chem Soc (2011) 1.15
Fast and accurate fitting of relaxation dispersion data using the flexible software package GLOVE. J Biomol NMR (2013) 1.09
Topology-based modeling of intrinsically disordered proteins: balancing intrinsic folding and intermolecular interactions. Proteins (2011) 1.08
Genes for Tfb2, Tfb3, and Tfb4 subunits of yeast transcription/repair factor IIH. Homology to human cyclin-dependent kinase activating kinase and IIH subunits. J Biol Chem (1997) 1.07
Cloning and characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH. EMBO J (1997) 1.05
The neural repressor NRSF/REST binds the PAH1 domain of the Sin3 corepressor by using its distinct short hydrophobic helix. J Mol Biol (2005) 1.02
The binding mechanisms of intrinsically disordered proteins. Phys Chem Chem Phys (2013) 1.00
Coupled folding and binding of the disordered protein PUMA does not require particular residual structure. J Am Chem Soc (2014) 1.00
HMGB1-facilitated p53 DNA binding occurs via HMG-Box/p53 transactivation domain interaction, regulated by the acidic tail. Structure (2012) 0.99
p53 and TFIIEalpha share a common binding site on the Tfb1/p62 subunit of TFIIH. Proc Natl Acad Sci U S A (2007) 0.99
Prepaying the entropic cost for allosteric regulation in KIX. Proc Natl Acad Sci U S A (2014) 0.98
Conformational propensities of intrinsically disordered proteins influence the mechanism of binding and folding. Proc Natl Acad Sci U S A (2015) 0.96
Structural Insight into the Mechanism of TFIIH Recognition by the Acidic String of the Nucleotide Excision Repair Factor XPC. Structure (2015) 0.95
Electrostatically accelerated encounter and folding for facile recognition of intrinsically disordered proteins. PLoS Comput Biol (2013) 0.95
Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH. Mol Cell (2015) 0.94
The allosteric communication pathways in KIX domain of CBP. Proc Natl Acad Sci U S A (2013) 0.93
Importance of electrostatic interactions in the association of intrinsically disordered histone chaperone Chz1 and histone H2A.Z-H2B. PLoS Comput Biol (2012) 0.92
Functional roles of transiently and intrinsically disordered regions within proteins. FEBS J (2015) 0.92
Theoretical perspectives on nonnative interactions and intrinsic disorder in protein folding and binding. Curr Opin Struct Biol (2014) 0.91
Role of electrostatic interactions in binding of peptides and intrinsically disordered proteins to their folded targets. 1. NMR and MD characterization of the complex between the c-Crk N-SH3 domain and the peptide Sos. Biochemistry (2014) 0.85
A virtual-system coupled multicanonical molecular dynamics simulation: principles and applications to free-energy landscape of protein-protein interaction with an all-atom model in explicit solvent. J Chem Phys (2013) 0.85
Ab initio simulation of a 57-residue protein in explicit solvent reproduces the native conformation in the lowest free-energy cluster. Protein Sci (2011) 0.85
Extended string binding mode of the phosphorylated transactivation domain of tumor suppressor p53. J Am Chem Soc (2014) 0.84
Multi-scale ensemble modeling of modular proteins with intrinsically disordered linker regions: application to p53. Biophys J (2014) 0.82
Conformational Ensembles of an Intrinsically Disordered Protein pKID with and without a KIX Domain in Explicit Solvent Investigated by All-Atom Multicanonical Molecular Dynamics. Biomolecules (2012) 0.81
Computational approaches for inferring the functions of intrinsically disordered proteins. Front Mol Biosci (2015) 0.81
Structural flexibility of intrinsically disordered proteins induces stepwise target recognition. J Chem Phys (2013) 0.78