IL-33 Precedes IL-5 in Regulating Eosinophil Commitment and Is Required for Eosinophil Homeostasis.

PubWeight™: 0.77‹?›

🔗 View Article (PMID 27683753)

Published in J Immunol on September 28, 2016

Authors

Laura K Johnston1, Chia-Lin Hsu1, Rebecca A Krier-Burris1, Krishan D Chhiba1, Karen B Chien1, Andrew McKenzie2, Sergejs Berdnikovs1, Paul J Bryce3

Author Affiliations

1: Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60610; and.
2: Medical Research Council Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom.
3: Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60610; and p-bryce@northwestern.edu.

Articles cited by this

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity (2005) 14.95

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature (2010) 10.34

The eosinophil. Annu Rev Immunol (2006) 7.06

The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'? PLoS One (2008) 4.52

T1/ST2 is preferentially expressed on murine Th2 cells, independent of interleukin 4, interleukin 5, and interleukin 10, and important for Th2 effector function. Proc Natl Acad Sci U S A (1998) 3.61

IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation. J Immunol (2009) 3.41

Eosinophilia in transgenic mice expressing interleukin 5. J Exp Med (1990) 3.29

IL-5-deficient mice have a developmental defect in CD5+ B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity (1996) 3.23

Type 2 innate lymphoid cells control eosinophil homeostasis. Nature (2013) 3.20

Eosinophils: changing perspectives in health and disease. Nat Rev Immunol (2012) 2.69

Expression of IL-5 in thymocytes/T cells leads to the development of a massive eosinophilia, extramedullary eosinophilopoiesis, and unique histopathologies. J Immunol (1997) 2.30

Functionally competent eosinophils differentiated ex vivo in high purity from normal mouse bone marrow. J Immunol (2008) 2.22

Identification of a lymphokine that stimulates eosinophil differentiation in vitro. Its relationship to interleukin 3, and functional properties of eosinophils produced in cultures. J Exp Med (1985) 2.22

An IL-1 cytokine member, IL-33, induces human basophil activation via its ST2 receptor. J Immunol (2008) 1.96

Identification of eosinophil lineage-committed progenitors in the murine bone marrow. J Exp Med (2005) 1.76

IL-33 exacerbates eosinophil-mediated airway inflammation. J Immunol (2010) 1.73

IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy. Ann Rheum Dis (2010) 1.62

IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization. J Allergy Clin Immunol (2012) 1.59

CD34+ hemopoietic progenitor cells are potent effectors of allergic inflammation. J Allergy Clin Immunol (2008) 1.56

IL-33 is produced by mast cells and regulates IgE-dependent inflammation. PLoS One (2010) 1.54

Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection. J Exp Med (2012) 1.49

IL-33 and IL-33 receptors in host defense and diseases. Allergol Int (2010) 1.48

Molecular and clinical rationale for therapeutic targeting of interleukin-5 and its receptor. Clin Exp Allergy (2011) 1.30

Lineage(-)Sca1+c-Kit(-)CD25+ cells are IL-33-responsive type 2 innate cells in the mouse bone marrow. J Immunol (2011) 1.22

IL-33-dependent induction of allergic lung inflammation by FcγRIII signaling. J Clin Invest (2013) 1.08

Antigen profiles for the quantitative assessment of eosinophils in mouse tissues by flow cytometry. J Immunol Methods (2011) 1.02

Interleukin 5 is protective during sepsis in an eosinophil-independent manner. Am J Respir Crit Care Med (2012) 1.00

Gene microarray analysis reveals interleukin-5-dependent transcriptional targets in mouse bone marrow. Blood (2003) 0.97

Intraperitoneal influx of neutrophils in response to IL-33 is mast cell-dependent. Blood (2012) 0.96

Expression of IL-5 alters bone metabolism and induces ossification of the spleen in transgenic mice. J Clin Invest (2001) 0.96

IL-33-induced hematopoietic stem and progenitor cell mobilization depends upon CCR2. J Immunol (2014) 0.92

The role of IL-33 and mast cells in allergy and inflammation. Clin Transl Allergy (2015) 0.91

Interleukin-33: a mediator of inflammation targeting hematopoietic stem and progenitor cells and their progenies. Front Immunol (2013) 0.91

Thymic stromal lymphopoietin and IL-33 modulate migration of hematopoietic progenitor cells in patients with allergic asthma. J Allergy Clin Immunol (2015) 0.91

Enhanced histopathology of the bone marrow. Toxicol Pathol (2006) 0.90

Interleukin (IL)-33: new therapeutic target for atopic diseases. J Pharmacol Sci (2014) 0.90

IL-33 signaling contributes to the pathogenesis of myeloproliferative neoplasms. J Clin Invest (2015) 0.89

IL-25 and IL-33 Contribute to Development of Eosinophilic Airway Inflammation in Epicutaneously Antigen-Sensitized Mice. PLoS One (2015) 0.88

IL-33, but not IL-25, is crucial for the development of house dust mite antigen-induced allergic rhinitis. PLoS One (2013) 0.88

IL-33 promotes eosinophilia in vivo and antagonizes IL-5-dependent eosinophil hematopoiesis ex vivo. Immunol Lett (2012) 0.88

Transcription Factor Repertoire of Homeostatic Eosinophilopoiesis. J Immunol (2015) 0.84

TLR-induced activation of neutrophils promotes histamine production via a PI3 kinase dependent mechanism. Immunol Lett (2011) 0.83

Comparative analysis of the kinetics of binding and internalization of IL-5 in murine IL-5 receptors of high and low affinity. J Immunol (1993) 0.81

Severe neutrophil-dominated inflammation and enhanced myelopoiesis in IL-33-overexpressing CMV/IL33 mice. J Immunol (2014) 0.78

Articles by these authors

Transcriptional Heterogeneity of Mast Cells and Basophils upon Activation. J Immunol (2017) 0.75