Published in Front Immunol on September 20, 2016
Cancer Immunoprevention and Public Health. Front Public Health (2017) 0.75
Uses of Next-Generation Sequencing Technologies for the Diagnosis of Primary Immunodeficiencies. Front Immunol (2017) 0.75
IL-17 and Th17 Cells. Annu Rev Immunol (2009) 23.02
Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science (1999) 11.04
IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature (2001) 11.03
IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia. Nat Med (2008) 9.05
Endogenous antimicrobial peptides and skin infections in atopic dermatitis. N Engl J Med (2002) 9.01
TH17 cells in development: an updated view of their molecular identity and genetic programming. Nat Rev Immunol (2008) 8.95
Impaired T(H)17 cell differentiation in subjects with autosomal dominant hyper-IgE syndrome. Nature (2008) 8.17
Common variable immunodeficiency: clinical and immunological features of 248 patients. Clin Immunol (1999) 7.25
The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature (2005) 7.18
A critical role for IL-21 in regulating immunoglobulin production. Science (2002) 7.09
Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome. Nature (2007) 7.07
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice. Proc Natl Acad Sci U S A (1998) 6.82
Cancer risk in the Swiss HIV Cohort Study: associations with immunodeficiency, smoking, and highly active antiretroviral therapy. J Natl Cancer Inst (2005) 6.69
Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice. J Infect Dis (2004) 6.54
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science (2011) 6.19
Cyclosporin A in patients receiving renal allografts from cadaver donors. Lancet (1979) 6.10
Regulation of cutaneous malignancy by gammadelta T cells. Science (2001) 5.83
NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity (2008) 5.35
Immune surveillance of tumors. J Clin Invest (2007) 5.04
Perforin gene defects in familial hemophagocytic lymphohistiocytosis. Science (1999) 4.93
The concept of immunological surveillance. Prog Exp Tumor Res (1970) 4.76
Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3. J Exp Med (2008) 4.76
Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium. Proc Natl Acad Sci U S A (1996) 4.69
Combined immunodeficiency associated with DOCK8 mutations. N Engl J Med (2009) 4.52
Practice parameter for the diagnosis and management of primary immunodeficiency. Ann Allergy Asthma Immunol (2005) 4.44
Broad tumor-associated expression and recognition by tumor-derived gamma delta T cells of MICA and MICB. Proc Natl Acad Sci U S A (1999) 4.40
A critical function for type I interferons in cancer immunoediting. Nat Immunol (2005) 4.14
Malignant lymphomas in transplantation patients. Transplant Proc (1969) 4.12
Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells. J Exp Med (2008) 3.85
IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J Immunol (2004) 3.84
Extreme hyperimmunoglobulinemia E and undue susceptibility to infection. Pediatrics (1972) 3.75
Common variable immunodeficiency disorders: division into distinct clinical phenotypes. Blood (2008) 3.44
Risk of cancer in renal-transplant recipients. Lancet (1973) 3.36
Job's Syndrome. Recurrent, "cold", staphylococcal abscesses. Lancet (1966) 3.27
Morbidity and mortality in common variable immune deficiency over 4 decades. Blood (2011) 3.18
JAKs and STATs in immunity, immunodeficiency, and cancer. N Engl J Med (2013) 3.07
Primary immunodeficiency diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency. Front Immunol (2011) 3.05
Perforin-mediated cytotoxicity is critical for surveillance of spontaneous lymphoma. J Exp Med (2000) 3.04
Perforin-mediated target-cell death and immune homeostasis. Nat Rev Immunol (2006) 3.04
Occurrence of leukemia and lymphoma in patients with agammaglobulinemia. Blood (1963) 3.03
Primary immunodeficiency diseases: an update from the International Union of Immunological Societies Primary Immunodeficiency Diseases Classification Committee. J Allergy Clin Immunol (2007) 2.98
GATA2 deficiency: a protean disorder of hematopoiesis, lymphatics, and immunity. Blood (2013) 2.82
The IL-23-IL-17 immune axis: from mechanisms to therapeutic testing. Nat Rev Immunol (2014) 2.82
Common variable immunodeficiency: a new look at an old disease. Lancet (2008) 2.75
Familial and acquired hemophagocytic lymphohistiocytosis. Annu Rev Med (2012) 2.73
Leukemia and lymphoma in ataxia telangiectasia. Blood (1996) 2.65
Primary immunodeficiency diseases: an update on the classification from the international union of immunological societies expert committee for primary immunodeficiency. Front Immunol (2014) 2.61
Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH. Blood (2011) 2.55
Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced T(H)17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE syndrome. J Allergy Clin Immunol (2008) 2.50
Association of the autoimmune disease scleroderma with an immunologic response to cancer. Science (2013) 2.46
Long-term follow-up and outcome of a large cohort of patients with common variable immunodeficiency. J Clin Immunol (2007) 2.43
B cell-intrinsic signaling through IL-21 receptor and STAT3 is required for establishing long-lived antibody responses in humans. J Exp Med (2010) 2.42
Ataxia-telangiectasia; a familial syndrome of progressive cerebellar ataxia, oculocutaneous telangiectasia and frequent pulmonary infection. Pediatrics (1958) 2.32
Occurrence of malignancy in immunodeficiency diseases. A literature review. Cancer (1971) 2.31
The hyper-IgE syndromes. Immunol Allergy Clin North Am (2008) 2.19
A critical role for STAT3 transcription factor signaling in the development and maintenance of human T cell memory. Immunity (2011) 2.15
Mortality and cancer incidence in 263 patients with ataxia-telangiectasia. J Natl Cancer Inst (1986) 2.14
Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis: Results of a long-term survey. Blood (2006) 2.03
Population prevalence of diagnosed primary immunodeficiency diseases in the United States. J Clin Immunol (2007) 2.03
Prospective study of cancer in patients with hypogammaglobulinaemia. Lancet (1985) 2.03
Autosomal recessive hyperimmunoglobulin E syndrome: a distinct disease entity. J Pediatr (2004) 2.01
XIAP mediates NOD signaling via interaction with RIP2. Proc Natl Acad Sci U S A (2009) 1.95
Hypercytokinemia in familial hemophagocytic lymphohistiocytosis. Blood (1991) 1.92
Hyper-IgE syndromes. Immunol Rev (2005) 1.92
Inborn errors of human JAKs and STATs. Immunity (2012) 1.90
Primary Immunodeficiency Diseases: an Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency 2015. J Clin Immunol (2015) 1.89
Suppression of lymphoma and epithelial malignancies effected by interferon gamma. J Exp Med (2002) 1.85
Perforin expression in cytotoxic lymphocytes from patients with hemophagocytic lymphohistiocytosis and their family members. Blood (2002) 1.79
Cholangiocarcinoma in primary sclerosing cholangitis is associated with NKG2D polymorphisms. Hepatology (2008) 1.79
DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice. J Exp Med (2011) 1.79
Epstein-Barr virus-associated lymphoproliferative disorders. Hum Pathol (2007) 1.76
Cancer risk among patients with IgA deficiency or common variable immunodeficiency and their relatives: a combined Danish and Swedish study. Clin Exp Immunol (2002) 1.74
A Mendelian predisposition to B-cell lymphoma caused by IL-10R deficiency. Blood (2013) 1.74
Are antibody deficiency disorders associated with a narrower range of cancers than other forms of immunodeficiency? Blood (2010) 1.71
DOCK8 functions as an adaptor that links TLR-MyD88 signaling to B cell activation. Nat Immunol (2012) 1.70
Cancer in children with primary or secondary immunodeficiencies. J Pediatr (1995) 1.70
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity. Mol Cell (2012) 1.66
Primary immunodeficiency disorders: antibody deficiency. J Allergy Clin Immunol (2002) 1.66
Cytokine production regulating Th1 and Th2 cytokines in hemophagocytic lymphohistiocytosis. Blood (1997) 1.60
Three distinct stages of B-cell defects in common varied immunodeficiency. Proc Natl Acad Sci U S A (1982) 1.60
Nijmegen breakage syndrome. J Med Genet (1996) 1.58
IL-17 and IL-22: siblings, not twins. Trends Immunol (2010) 1.56
Checkpoint blocking antibodies in cancer immunotherapy. FEBS Lett (2013) 1.54
Spectrum of perforin gene mutations in familial hemophagocytic lymphohistiocytosis. Am J Hum Genet (2001) 1.53
Incidence of cancer in 98 patients with common varied immunodeficiency. J Clin Immunol (1987) 1.53
Cholangiopathy and tumors of the pancreas, liver, and biliary tree in boys with X-linked immunodeficiency with hyper-IgM. J Immunol (1997) 1.52
Genotype-phenotype study of familial haemophagocytic lymphohistiocytosis due to perforin mutations. J Med Genet (2007) 1.44
Inborn errors of human IL-17 immunity underlie chronic mucocutaneous candidiasis. Curr Opin Allergy Clin Immunol (2012) 1.43
Inability to resolve specific infection generates innate immunodeficiency syndrome in Xiap-/- mice. Blood (2014) 1.41
Diagnostic approach to primary immunodeficiency disorders. Indian Pediatr (2013) 1.40
Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies. Nucleic Acids Res (2012) 1.38
Pathogenesis, diagnosis, and management of primary antibody deficiencies and infections. Clin Microbiol Rev (2009) 1.38
Functional consequences of perforin gene mutations in 22 patients with familial haemophagocytic lymphohistiocytosis. Br J Haematol (2002) 1.34
Immunodeficiency disease and malignancy. Various immunologic deficiencies of man and the role of immune processes in the control of malignant disease. Ann Intern Med (1972) 1.34
The hyper-IgE syndrome. Clin Rev Allergy Immunol (2001) 1.31
Autosomal dominant STAT3 deficiency and hyper-IgE syndrome: molecular, cellular, and clinical features from a French national survey. Medicine (Baltimore) (2012) 1.31
Effect of transcription factor GATA-2 on phagocytic activity of alveolar macrophages from Pneumocystis carinii-infected hosts. Infect Immun (2003) 1.29
Autosomal recessive phosphoglucomutase 3 (PGM3) mutations link glycosylation defects to atopy, immune deficiency, autoimmunity, and neurocognitive impairment. J Allergy Clin Immunol (2014) 1.26
Wiskott-Aldrich syndrome: a comprehensive review. Ann N Y Acad Sci (2013) 1.25
Dedicator of cytokinesis 8 (DOCK8) deficiency. Curr Opin Allergy Clin Immunol (2010) 1.24