Published in Nature on July 03, 2005
Senescence of activated stellate cells limits liver fibrosis. Cell (2008) 8.98
NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity (2008) 5.35
CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell (2009) 5.22
Aging, cellular senescence, and cancer. Annu Rev Physiol (2012) 5.08
Immunogenic and tolerogenic cell death. Nat Rev Immunol (2009) 4.34
The anticancer immune response: indispensable for therapeutic success? J Clin Invest (2008) 4.01
Patterns of pathogenesis: discrimination of pathogenic and nonpathogenic microbes by the innate immune system. Cell Host Microbe (2009) 3.86
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities. J Clin Invest (2013) 3.47
Targeting natural killer cells and natural killer T cells in cancer. Nat Rev Immunol (2012) 3.43
Activation, coactivation, and costimulation of resting human natural killer cells. Immunol Rev (2006) 3.30
Effect of NKG2D ligand expression on host immune responses. Immunol Rev (2010) 3.08
Combining radiotherapy and cancer immunotherapy: a paradigm shift. J Natl Cancer Inst (2013) 3.07
Regulation of ligands for the NKG2D activating receptor. Annu Rev Immunol (2013) 2.98
Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells. Blood (2009) 2.75
Why do viruses cause cancer? Highlights of the first century of human tumour virology. Nat Rev Cancer (2010) 2.68
New insights into cancer immunoediting and its three component phases--elimination, equilibrium and escape. Curr Opin Immunol (2014) 2.47
Oncogenic stress sensed by the immune system: role of natural killer cell receptors. Nat Rev Immunol (2009) 2.44
DNA damage checkpoints in stem cells, ageing and cancer. Nat Rev Mol Cell Biol (2012) 2.39
Identification of the target self-antigens in reperfusion injury. J Exp Med (2006) 2.38
Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway. Immunity (2007) 2.23
Liver natural killer and natural killer T cells: immunobiology and emerging roles in liver diseases. J Leukoc Biol (2009) 2.17
Line of attack: NK cell specificity and integration of signals. Curr Opin Immunol (2008) 2.15
DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance. Nature (2013) 2.13
Effect of mindfulness based stress reduction on immune function, quality of life and coping in women newly diagnosed with early stage breast cancer. Brain Behav Immun (2008) 2.11
Activation of NK cells by an endocytosed receptor for soluble HLA-G. PLoS Biol (2006) 2.08
Interleukin-22-producing innate immune cells: new players in mucosal immunity and tissue repair? Nat Rev Immunol (2009) 2.04
Intestinal mucosal inflammation leads to systemic genotoxicity in mice. Cancer Res (2009) 1.90
Therapy-induced antibodies to MHC class I chain-related protein A antagonize immune suppression and stimulate antitumor cytotoxicity. Proc Natl Acad Sci U S A (2006) 1.88
Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors. J Exp Med (2012) 1.86
Continuous engagement of a self-specific activation receptor induces NK cell tolerance. J Exp Med (2008) 1.86
Unifying concepts of MHC-dependent natural killer cell education. Trends Immunol (2011) 1.85
HIV modulates the expression of ligands important in triggering natural killer cell cytotoxic responses on infected primary T-cell blasts. Blood (2007) 1.83
Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA*008 that is shed by tumor cells in exosomes. Cancer Res (2010) 1.81
Macrophages as mediators of tumor immunosurveillance. Trends Immunol (2010) 1.80
The intraepithelial T cell response to NKG2D-ligands links lymphoid stress surveillance to atopy. Science (2011) 1.78
Radiation as an immunological adjuvant: current evidence on dose and fractionation. Front Oncol (2012) 1.76
A role for NKG2D in NK cell-mediated resistance to poxvirus disease. PLoS Pathog (2008) 1.72
Gamma-herpesvirus kinase actively initiates a DNA damage response by inducing phosphorylation of H2AX to foster viral replication. Cell Host Microbe (2007) 1.71
HIV-1 Vpr triggers natural killer cell-mediated lysis of infected cells through activation of the ATR-mediated DNA damage response. PLoS Pathog (2009) 1.71
Dendritic cells release HLA-B-associated transcript-3 positive exosomes to regulate natural killer function. PLoS One (2008) 1.63
HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing. Blood (2009) 1.63
Proteasome regulation of ULBP1 transcription. J Immunol (2009) 1.61
Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer. Cell Death Differ (2013) 1.60
MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma. Proc Natl Acad Sci U S A (2008) 1.59
Suppressing T cell motility induced by anti-CTLA-4 monotherapy improves antitumor effects. J Clin Invest (2012) 1.55
Regulation of ligands for the activating receptor NKG2D. Immunology (2007) 1.55
Prolonged mitotic arrest triggers partial activation of apoptosis, resulting in DNA damage and p53 induction. Mol Biol Cell (2011) 1.53
NKG2D ligand expression in human colorectal cancer reveals associations with prognosis and evidence for immunoediting. Clin Cancer Res (2009) 1.50
Distinct requirements of microRNAs in NK cell activation, survival, and function. J Immunol (2010) 1.48
The human cytomegalovirus microRNA miR-UL112 acts synergistically with a cellular microRNA to escape immune elimination. Nat Immunol (2010) 1.48
Natural killer cells in infection and inflammation of the lung. Immunology (2009) 1.46
Blockade of NKG2D on NKT cells prevents hepatitis and the acute immune response to hepatitis B virus. Proc Natl Acad Sci U S A (2007) 1.46
c-Myc regulates expression of NKG2D ligands ULBP1/2/3 in AML and modulates their susceptibility to NK-mediated lysis. Blood (2014) 1.45
Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status. Aging Cell (2010) 1.43
Agonist anti-GITR monoclonal antibody and stereotactic radiation induce immune-mediated survival advantage in murine intracranial glioma. J Immunother Cancer (2016) 1.41
Mechanical stress downregulates MHC class I expression on human cancer cell membrane. PLoS One (2014) 1.41
Posttranslational regulation of the NKG2D ligand Mult1 in response to cell stress. J Exp Med (2009) 1.41
Multiplicity and plasticity of natural killer cell signaling pathways. Blood (2005) 1.40
Costimulation of dendritic epidermal gammadelta T cells by a new NKG2D ligand expressed specifically in the skin. J Immunol (2009) 1.36
Blocking NK cell inhibitory self-recognition promotes antibody-dependent cellular cytotoxicity in a model of anti-lymphoma therapy. J Immunol (2008) 1.35
The antiviral factor APOBEC3G enhances the recognition of HIV-infected primary T cells by natural killer cells. Nat Immunol (2011) 1.35
p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells. J Exp Med (2013) 1.34
The tumor-immune microenvironment and response to radiation therapy. J Mammary Gland Biol Neoplasia (2010) 1.33
NKG2D in NK and T cell-mediated immunity. J Clin Immunol (2005) 1.32
Human NK cells of mice with reconstituted human immune system components require preactivation to acquire functional competence. Blood (2010) 1.32
Immunologic privilege in the central nervous system and the blood-brain barrier. J Cereb Blood Flow Metab (2012) 1.30
Altered NK cell development and enhanced NK cell-mediated resistance to mouse cytomegalovirus in NKG2D-deficient mice. Immunity (2009) 1.29
The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response. PLoS One (2008) 1.29
Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect. Invest New Drugs (2010) 1.27
Differential mechanisms of shedding of the glycosylphosphatidylinositol (GPI)-anchored NKG2D ligands. J Biol Chem (2010) 1.27
Recognition of tumors by the innate immune system and natural killer cells. Adv Immunol (2014) 1.27
NKG2D ligands as therapeutic targets. Cancer Immun (2013) 1.26
Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase. Immunity (2010) 1.25
Do all of the neurologic diseases in patients with DNA repair gene mutations result from the accumulation of DNA damage? DNA Repair (Amst) (2008) 1.25
Delineation of antigen-specific and antigen-nonspecific CD8(+) memory T-cell responses after cytokine-based cancer immunotherapy. Blood (2012) 1.25
NKG2D Receptor and Its Ligands in Host Defense. Cancer Immunol Res (2015) 1.25
Exosome removal as a therapeutic adjuvant in cancer. J Transl Med (2012) 1.24
Macrophage migration inhibitory factor contributes to the immune escape of ovarian cancer by down-regulating NKG2D. J Immunol (2008) 1.23
An integrated view of the regulation of NKG2D ligands. Immunology (2009) 1.23
Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome. J Immunol (2009) 1.22
Natural killer cell signal integration balances synapse symmetry and migration. PLoS Biol (2009) 1.22
Decreased Dicer expression elicits DNA damage and up-regulation of MICA and MICB. J Cell Biol (2008) 1.20
ATM-mediated transcriptional and developmental responses to gamma-rays in Arabidopsis. PLoS One (2007) 1.20
Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance. Proc Natl Acad Sci U S A (2008) 1.20
RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry. J Exp Med (2012) 1.20
Focus on TILs: Prognostic significance of tumor infiltrating lymphocytes in human glioma. Cancer Immun (2007) 1.20
Adenovirus serotype 5 E1A sensitizes tumor cells to NKG2D-dependent NK cell lysis and tumor rejection. J Exp Med (2005) 1.18
Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse. Mol Cell Biol (2007) 1.18
Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation. Cancer Res (2010) 1.17
Ly49H signaling through DAP10 is essential for optimal natural killer cell responses to mouse cytomegalovirus infection. J Exp Med (2009) 1.16
Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease. J Clin Invest (2009) 1.16
Physiological and pathological consequences of cellular senescence. Cell Mol Life Sci (2014) 1.15
Soluble MICA and a MICA variation as possible prognostic biomarkers for HBV-induced hepatocellular carcinoma. PLoS One (2012) 1.15
NK cells sense tumors, course of disease and treatments: Consequences for NK-based therapies. Oncoimmunology (2012) 1.15
Replicative stress, stem cells and aging. Mech Ageing Dev (2008) 1.14
NK cells are effectors for resolvin E1 in the timely resolution of allergic airway inflammation. J Immunol (2011) 1.13
Regulation of immune cell function and differentiation by the NKG2D receptor. Cell Mol Life Sci (2011) 1.12
TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells. Nat Cell Biol (2013) 1.12
Role of T lymphocytes in tumor response to radiotherapy. Front Oncol (2012) 1.12
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature (2003) 20.13
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature (2005) 18.30
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints. Annu Rev Biochem (2004) 14.93
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions. Nature (2005) 14.65
Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev (2001) 12.46
Turnover of naive- and memory-phenotype T cells. J Exp Med (1994) 8.07
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res (1999) 7.82
Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell (2003) 7.48
ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes Dev (2000) 7.28
Roles of the NKG2D immunoreceptor and its ligands. Nat Rev Immunol (2003) 6.95
Toward maintaining the genome: DNA damage and replication checkpoints. Annu Rev Genet (2002) 6.10
Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages. Nat Immunol (2000) 5.45
Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance. Genes Dev (2003) 4.40
The role of the NKG2D immunoreceptor in immune cell activation and natural killing. Immunity (2002) 3.85
Checking on the fork: the DNA-replication stress-response pathway. Trends Cell Biol (2002) 3.66
Targeting the checkpoint kinases: chemosensitization versus chemoprotection. Nat Rev Cancer (2004) 3.06
NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules. J Exp Med (2003) 2.75
The role of DNA breaks in genomic instability and tumorigenesis. Immunol Rev (2003) 2.72
GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation. Immunity (2003) 2.63
Genomic instability--the engine of tumorigenesis? Nat Rev Cancer (2003) 2.27
A procedure for culture of cells from mouse tail biopsies: brief communication. J Natl Cancer Inst (1978) 2.22
A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity. Eur J Immunol (2003) 1.78
Interactions of viruses with the cellular DNA repair machinery. DNA Repair (Amst) (2004) 1.72
Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response. Mol Cell Biol (2004) 1.63
A genetically defined mouse ovarian carcinoma model for the molecular characterization of pathway-targeted therapy and tumor resistance. Proc Natl Acad Sci U S A (2005) 1.60
p73alpha regulation by Chk1 in response to DNA damage. Mol Cell Biol (2003) 1.36
Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1. Oncogene (2003) 1.33
Mismatch repair and response to DNA-damaging antitumour therapies. Eur J Cancer (2003) 1.26
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors. Science (2002) 17.71
Innate or adaptive immunity? The example of natural killer cells. Science (2011) 8.68
Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss. Cell Stem Cell (2007) 6.02
NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy. Immunity (2008) 5.35
A subset of natural killer cells achieves self-tolerance without expressing inhibitory receptors specific for self-MHC molecules. Blood (2005) 4.64
Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease. Immunity (2004) 4.36
The role of the NKG2D immunoreceptor in immune cell activation and natural killing. Immunity (2002) 3.85
A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT-6 secretion. Mol Microbiol (2004) 3.53
Acute postnatal ablation of Hif-2alpha results in anemia. Proc Natl Acad Sci U S A (2007) 3.51
Distinct expression levels and patterns of stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1), in human epithelial cancers. PLoS One (2010) 3.38
Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development. Mol Cell Biol (2004) 3.20
Selective associations with signaling proteins determine stimulatory versus costimulatory activity of NKG2D. Nat Immunol (2002) 2.87
C-terminal signal sequence promotes virulence factor secretion in Mycobacterium tuberculosis. Science (2006) 2.72
Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis. EMBO J (2007) 2.61
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk. PLoS Genet (2013) 2.39
Activation of Notch1 signaling is required for beta-catenin-mediated human primary melanoma progression. J Clin Invest (2005) 2.38
Mycobacterium marinum escapes from phagosomes and is propelled by actin-based motility. J Exp Med (2003) 2.30
Positive selection of dendritic epidermal gammadelta T cell precursors in the fetal thymus determines expression of skin-homing receptors. Immunity (2004) 2.19
Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases. Nat Immunol (2006) 2.15
NK cell responsiveness is tuned commensurate with the number of inhibitory receptors for self-MHC class I: the rheostat model. J Immunol (2009) 2.12
Turnover and proliferation of NK cells in steady state and lymphopenic conditions. J Immunol (2004) 2.07
Mature natural killer cells reset their responsiveness when exposed to an altered MHC environment. J Exp Med (2010) 2.06
ESX-1-dependent cytolysis in lysosome secretion and inflammasome activation during mycobacterial infection. Cell Microbiol (2008) 2.01
A mycobacterium ESX-1-secreted virulence factor with unique requirements for export. PLoS Pathog (2007) 2.00
Systematic genetic nomenclature for type VII secretion systems. PLoS Pathog (2009) 1.96
Requirement for kasB in Mycobacterium mycolic acid biosynthesis, cell wall impermeability and intracellular survival: implications for therapy. Mol Microbiol (2003) 1.91
PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation. EMBO Rep (2009) 1.89
Redundant and unique roles of two enhancer elements in the TCRgamma locus in gene regulation and gammadelta T cell development. Immunity (2002) 1.88
Combining ATR suppression with oncogenic Ras synergistically increases genomic instability, causing synthetic lethality or tumorigenesis in a dosage-dependent manner. Cancer Res (2010) 1.82
A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity. Eur J Immunol (2003) 1.78
Hippo pathway effector Yap is an ovarian cancer oncogene. Cancer Res (2010) 1.77
Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors. Proc Natl Acad Sci U S A (2004) 1.76
Regulation of NK cell responsiveness to achieve self-tolerance and maximal responses to diseased target cells. Immunol Rev (2008) 1.74
Development and selection of gammadelta T cells. Immunol Rev (2007) 1.70
The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression. Proc Natl Acad Sci U S A (2006) 1.67
Macrophage complement receptors and pathogen clearance. Cell Microbiol (2007) 1.65
A genetically defined mouse ovarian carcinoma model for the molecular characterization of pathway-targeted therapy and tumor resistance. Proc Natl Acad Sci U S A (2005) 1.60
Mouse models of cancer. Annu Rev Pathol (2011) 1.59
The innate immune response to tumors and its role in the induction of T-cell immunity. Immunol Rev (2002) 1.59
HIF2alpha inhibition promotes p53 pathway activity, tumor cell death, and radiation responses. Proc Natl Acad Sci U S A (2009) 1.59
Transposon mutagenesis of Mycobacterium marinum identifies a locus linking pigmentation and intracellular survival. Infect Immun (2003) 1.59
ATR and H2AX cooperate in maintaining genome stability under replication stress. J Biol Chem (2008) 1.55
Atg5-independent sequestration of ubiquitinated mycobacteria. PLoS Pathog (2009) 1.55
Mechanisms of Cables 1 gene inactivation in human ovarian cancer development. Cancer Biol Ther (2007) 1.54
RPA accumulation during class switch recombination represents 5'-3' DNA-end resection during the S-G2/M phase of the cell cycle. Cell Rep (2013) 1.53
Tissue regenerative delays and synthetic lethality in adult mice after combined deletion of Atr and Trp53. Nat Genet (2009) 1.51
NK cells respond to pulmonary infection with Mycobacterium tuberculosis, but play a minimal role in protection. J Immunol (2003) 1.49
Comparative analysis of human NK cell activation induced by NKG2D and natural cytotoxicity receptors. Eur J Immunol (2004) 1.48
Interactions between CD47 and thrombospondin reduce inflammation. J Immunol (2007) 1.46
Activation and self-tolerance of natural killer cells. Immunol Rev (2006) 1.46
HOXB13 promotes ovarian cancer progression. Proc Natl Acad Sci U S A (2007) 1.46
A collagen-remodeling gene signature regulated by TGF-β signaling is associated with metastasis and poor survival in serous ovarian cancer. Clin Cancer Res (2013) 1.46
Oncogenic stress sensitizes murine cancers to hypomorphic suppression of ATR. J Clin Invest (2011) 1.46
Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells. J Immunol (2010) 1.46
Cytokine therapy reverses NK cell anergy in MHC-deficient tumors. J Clin Invest (2014) 1.45
Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8(+) T cells. J Immunol (2002) 1.44
Mycobacterium marinum: the generalization and specialization of a pathogenic mycobacterium. Microbes Infect (2004) 1.43
Posttranslational regulation of the NKG2D ligand Mult1 in response to cell stress. J Exp Med (2009) 1.41
Multiplicity and plasticity of natural killer cell signaling pathways. Blood (2005) 1.40
Implications of CD94 deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire formation. Proc Natl Acad Sci U S A (2002) 1.38
Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis are required for genomic stability. Mol Cell Biol (2008) 1.37
Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer. Cancer Res (2005) 1.36
Costimulation of dendritic epidermal gammadelta T cells by a new NKG2D ligand expressed specifically in the skin. J Immunol (2009) 1.36
The DNA damage response arouses the immune system. Cancer Res (2006) 1.35
p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells. J Exp Med (2013) 1.34
Polar localization of virulence-related Esx-1 secretion in mycobacteria. PLoS Pathog (2009) 1.32
Host-detrimental role of Esx-1-mediated inflammasome activation in mycobacterial infection. PLoS Pathog (2010) 1.31
A mycobacterial operon essential for virulence in vivo and invasion and intracellular persistence in macrophages. Infect Immun (2006) 1.31
Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint. Nature (2010) 1.29
A mouse model for the molecular characterization of brca1-associated ovarian carcinoma. Cancer Res (2006) 1.28
Role of the WASP family proteins for Mycobacterium marinum actin tail formation. Proc Natl Acad Sci U S A (2005) 1.25
Role for plastin in host defense distinguishes integrin signaling from cell adhesion and spreading. Immunity (2003) 1.21
Murine cytomegalovirus interference with antigen presentation has little effect on the size or the effector memory phenotype of the CD8 T cell response. J Immunol (2004) 1.20
Aberrant Epstein-Barr viral infection in systemic lupus erythematosus. Autoimmun Rev (2009) 1.20
Evidence that the red cell skeleton protein 4.2 interacts with the Rh membrane complex member CD47. Blood (2002) 1.20
Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells. Proc Natl Acad Sci U S A (2010) 1.20
RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry. J Exp Med (2012) 1.20
CD47 deficiency protects mice from lipopolysaccharide-induced acute lung injury and Escherichia coli pneumonia. J Immunol (2008) 1.19
Mechanisms of CD47-induced caspase-independent cell death in normal and leukemic cells: link between phosphatidylserine exposure and cytoskeleton organization. Blood (2002) 1.19
A delicate dance: host response to mycobacteria. Curr Opin Immunol (2011) 1.18
A co-operative interaction between Neisseria gonorrhoeae and complement receptor 3 mediates infection of primary cervical epithelial cells. Cell Microbiol (2002) 1.18
RNF4 and PLK1 are required for replication fork collapse in ATR-deficient cells. Genes Dev (2013) 1.17
Tim-Tipin dysfunction creates an indispensible reliance on the ATR-Chk1 pathway for continued DNA synthesis. J Cell Biol (2009) 1.15
Innate immune recognition by stimulatory immunoreceptors. Curr Opin Immunol (2003) 1.15
Replicative stress, stem cells and aging. Mech Ageing Dev (2008) 1.14
Actin-based motility of intracellular bacteria, and polarized surface distribution of the bacterial effector molecules. J Cell Physiol (2006) 1.14
A role for BRCA1 in uterine leiomyosarcoma. Cancer Res (2009) 1.13
Cytosol as battleground: ubiquitin as a weapon for both host and pathogen. Trends Cell Biol (2010) 1.13
IFN-gamma-mediated negative feedback regulation of NKT-cell function by CD94/NKG2. Blood (2005) 1.12
DNA mismanagement leads to immune system oversight. Cell (2007) 1.12
Chemotherapy-induced genotoxic stress promotes sensitivity to natural killer cell cytotoxicity by enabling missing-self recognition. Cancer Res (2010) 1.11
ATM-dependent spontaneous regression of early Eμ-myc-induced murine B-cell leukemia depends on natural killer and T cells. Blood (2013) 1.09
The ubiquitin-related protein PLIC-1 regulates heterotrimeric G protein function through association with Gbetagamma. J Cell Biol (2003) 1.09
Dual regulation of SIRPalpha phosphorylation by integrins and CD47. J Biol Chem (2007) 1.08
Role for lysosomal enzyme beta-hexosaminidase in the control of mycobacteria infection. Proc Natl Acad Sci U S A (2008) 1.08
Global gene expression of methicillin-resistant Staphylococcus aureus USA300 during human and mouse infection. J Infect Dis (2013) 1.07
Conditional deletion of SLP-76 in mature T cells abrogates peripheral immune responses. Eur J Immunol (2011) 1.07
MUC16 expression during embryogenesis, in adult tissues, and ovarian cancer in the mouse. Differentiation (2008) 1.07
Genomic Ly49A transgenes: basis of variegated Ly49A gene expression and identification of a critical regulatory element. J Immunol (2004) 1.05