Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract.

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Published in Elife on October 18, 2016

Authors

Koning Shen1,2, Barbara Calamini3, Jonathan A Fauerbach1,2, Boxue Ma4, Sarah H Shahmoradian4, Ivana L Serrano Lachapel1,2, Wah Chiu4, Donald C Lo3, Judith Frydman5

Author Affiliations

1: Department of Biology, Stanford University, Stanford, United States.
2: Department of Genetics, Stanford University, Stanford, United States.
3: Center for Drug Discovery, Department of Neurobiology, Duke University Medical Center, Durham, United States.
4: Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, United States.
5: Department of Biology, Stanford University, Stanford, California 94305-5430, USA.

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