Genetic Polymorphisms in the Long Noncoding RNA MIR2052HG Offer a Pharmacogenomic Basis for the Response of Breast Cancer Patients to Aromatase Inhibitor Therapy.

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Published in Cancer Res on October 10, 2016

Authors

James N Ingle1, Fang Xie2, Matthew J Ellis3, Paul E Goss4, Lois E Shepherd5, Judith-Anne W Chapman5, Bingshu E Chen5, Michiaki Kubo6, Yoichi Furukawa7, Yukihide Momozawa6, Vered Stearns8, Kathleen I Pritchard9, Poulami Barman10, Erin E Carlson10, Matthew P Goetz11, Richard M Weinshilboum2, Krishna R Kalari10, Liewei Wang2

Author Affiliations

1: Division of Medical Oncology, Mayo Clinic, Rochester, Minnesota. ingle.james@mayo.edu.
2: Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota.
3: Baylor Breast Center, Houston, Texas.
4: Massachusetts General Hospital Cancer Center, Harvard University, Boston, Massachusetts.
5: Canadian Cancer Trials Group, Kingston, Ontario, Canada.
6: RIKEN Center for Integrative Medical Science, Yokohama, Japan.
7: University of Tokyo, Tokyo, Japan.
8: Johns Hopkins School of Medicine, Baltimore, Maryland.
9: Sunnybrook Odette Regional Cancer Centre, University of Toronto, Toronto, Ontario, Canada.
10: Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.
11: Division of Medical Oncology, Mayo Clinic, Rochester, Minnesota.

Associated clinical trials:

Exemestane or Anastrozole in Treating Postmenopausal Women Who Have Undergone Surgery for Primary Breast Cancer | NCT00066573

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