PubRank

L A Chasin

Author PubWeight™ 89.01‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity. Proc Natl Acad Sci U S A 1980 7.84
2 Nonsense mutations in the dihydrofolate reductase gene affect RNA processing. Mol Cell Biol 1989 5.19
3 Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line. Proc Natl Acad Sci U S A 1978 4.60
4 Mutations affecting adenine phosphoribosyl transferase activity in Chinese hamster cells. Cell 1974 3.61
5 Mutant alleles for hypoxanthine phosphoriboxyltransferase: codominant expression, complementation, and segregation in hybrid Chinese hamster cells. Somatic Cell Genet 1976 3.38
6 Induction and repression of the histidine-degrading enzymes of Bacillus subtilis. J Biol Chem 1968 3.36
7 Deletion of the diploid dihydrofolate reductase locus from cultured mammalian cells. Cell 1983 2.97
8 Multiple splicing defects in an intronic false exon. Mol Cell Biol 2000 2.97
9 Multiple transcription start sites, DNase I-hypersensitive sites, and an opposite-strand exon in the 5' region of the CHO dhfr gene. Mol Cell Biol 1986 2.82
10 Transformation of the gene for hypoxanthine phosphoribosyltransferase. Somatic Cell Genet 1979 2.42
11 Point mutation analysis in a mammalian gene: rapid preparation of total RNA, PCR amplification of cDNA, and Taq sequencing by a novel method. Biotechniques 1989 2.17
12 Separation of linked markers in Chinese hamster cell hybrids: mitotic recombination is not involved. Genetics 1978 2.11
13 Effect of gamma rays at the dihydrofolate reductase locus: deletions and inversions. Somat Cell Mol Genet 1986 2.03
14 Order of intron removal during splicing of endogenous adenine phosphoribosyltransferase and dihydrofolate reductase pre-mRNA. Mol Cell Biol 1993 1.85
15 Human genomic sequences that inhibit splicing. Mol Cell Biol 2000 1.73
16 Structure of the dihydrofolate reductase gene in Chinese hamster ovary cells. Nucleic Acids Res 1983 1.68
17 Splicing mutants and their second-site suppressors at the dihydrofolate reductase locus in Chinese hamster ovary cells. Mol Cell Biol 1993 1.58
18 Direct selection for mutations affecting specific splice sites in a hamster dihydrofolate reductase minigene. Mol Cell Biol 1993 1.57
19 Control of 3' splice site choice in vivo by ASF/SF2 and hnRNP A1. Nucleic Acids Res 1999 1.52
20 Isolation of mammalian cell mutants deficient in glucose-6-phosphate dehydrogenase activity: linkage to hypoxanthine phosphoribosyl transferase. Proc Natl Acad Sci U S A 1975 1.48
21 Anchorage of the Chinese hamster dihydrofolate reductase gene to the nuclear scaffold occurs in an intragenic region. J Mol Biol 1987 1.48
22 Biosynthesis of dipicolinic acid in Bacillus subtilis. Biochem Biophys Res Commun 1967 1.43
23 The effect of ploidy on chemical mutagenesis in cultured Chinese hamster cells. J Cell Physiol 1973 1.36
24 Effects of nonsense mutations on nuclear and cytoplasmic adenine phosphoribosyltransferase RNA. Mol Cell Biol 1996 1.31
25 Non-linkage of induced mutations in Chinese hamster cells. Nat New Biol 1972 1.20
26 Deletion analysis of the Chinese hamster dihydrofolate reductase gene promoter. J Biol Chem 1988 1.14
27 Large exon size does not limit splicing in vivo. Mol Cell Biol 1994 1.11
28 Reversion of a Chinese hamster cell auxotrophic mutant. Proc Natl Acad Sci U S A 1974 1.11
29 A domain of methylation change at the albumin locus in rat hepatoma cell variants. Mol Cell Biol 1985 1.09
30 Direct demonstration of genetic alterations at the dihydrofolate reductase locus after gamma irradiation. Mol Cell Biol 1982 1.06
31 Mapping and characterization of mutations induced by benzo[a]pyrene diol epoxide at dihydrofolate reductase locus in CHO cells. Somat Cell Mol Genet 1988 1.00
32 Splicing mutations in the CHO DHFR gene preferentially induced by (+/-)-3 alpha,4 beta-dihydroxy-1 alpha,2 alpha-epoxy-1,2,3,4- tetrahydrobenzo[c]phenanthrene. Proc Natl Acad Sci U S A 1990 1.00
33 Efficient cloning of single-copy genes using specialized cosmid vectors: isolation of mutant dihydrofolate reductase genes. Proc Natl Acad Sci U S A 1985 0.96
34 Polyadenylation of Chinese hamster dihydrofolate reductase genomic genes and minigenes after gene transfer. Somat Cell Mol Genet 1987 0.95
35 Cointegration of DNA molecules introduced into mammalian cells by electroporation. Somat Cell Mol Genet 1998 0.95
36 Selective killing of methotrexate-resistant cells carrying amplified dihydrofolate reductase genes. Cancer Res 1981 0.93
37 DNA base changes and RNA levels in N-acetoxy-2-acetylaminofluorene-induced dihydrofolate reductase mutants of Chinese hamster ovary cells. J Mol Biol 1989 0.90
38 Gene expression after transformation of Bacillus subtilis. J Bacteriol 1970 0.90
39 Effect of differential polyadenylation and cell growth phase on dihydrofolate reductase mRNA stability. J Biol Chem 1999 0.89
40 Immortalization of normal liver functions in cell culture: rat hepatocyte-hepatoma cell hybrids expressing ornithine carbamoyltransferase activity. J Cell Physiol 1979 0.89
41 Retinoblastoma protein associates with SP1 and activates the hamster dihydrofolate reductase promoter. Oncogene 1998 0.88
42 Characterization of mutations induced by 2-(N-acetoxy-N-acetyl)aminofluorene in the dihydrofolate reductase gene of cultured hamster cells. Proc Natl Acad Sci U S A 1986 0.86
43 Chromosome-wide event accompanies the expression of recessive mutations in tetraploid cells. Science 1975 0.86
44 An alternatively spliced Pit-1 isoform altered in its ability to trans-activate. Nucleic Acids Res 1992 0.85
45 Cell-growth regulation of the hamster dihydrofolate reductase gene promoter by transcription factor Sp1. Eur J Biochem 1997 0.84
46 Mutants of Chinese hamster ovary cells with altered glucose-6-phosphate dehydrogenase activity. Somatic Cell Genet 1977 0.84
47 Multihormonal induction of alpha 2u-globulin in an established rat hepatoma cell line. J Cell Physiol 1982 0.83
48 Use of fluorescence-activated cell sorter to isolate mutant mammalian cells deficient in an internal protein, dihydrofolate reductase. Somat Cell Mol Genet 1985 0.81
49 Point mutational analysis of the hamster dihydrofolate reductase minimum promoter. J Biol Chem 1992 0.81
50 Repetitive cloning of mutant genes using locus-specific sticky ends. Methods Enzymol 1987 0.80
51 Use of a selectable reporter for the isolation of mammalian regulatory genes. Gene 1990 0.79
52 The rat albumin gene promoter is appropriately regulated in transient but not in stable transfections. Nucleic Acids Res 1988 0.79
53 Rat serum albumin synthesis in variant rat hepatoma cells. J Cell Physiol 1983 0.79
54 A mutational hot spot induced by N-hydroxy-aminofluorene in dihydrofolate reductase mutants of Chinese hamster ovary cells. Carcinogenesis 1993 0.75
55 In vivo photoreaction of a chiral cobalt complex: DNA cleavage by Co(DIP)3(3+) in mammalian cells. Mutat Res 1988 0.75