CD8+ T Cells and Endogenous IL-10 Are Required for Resolution of Chemotherapy-Induced Neuropathic Pain.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27798187)

Published in J Neurosci on October 26, 2016

Authors

Karen Krukowski1, Niels Eijkelkamp2, Geoffroy Laumet1, C Erik Hack3, Yan Li4, Patrick M Dougherty4, Cobi J Heijnen5, Annemieke Kavelaars6

Author Affiliations

1: Laboratory of Neuroimmunology, Division of Internal Medicine, and.
2: Laboratories of Translational Immunology and Neuroimmunology and Developmental Origins of Disease and n.eijkelkamp@umcutrecht.nl.
3: Laboratory of Translational Immunology, and.
4: Department of Anesthesiology and Pain Medicine Research, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, and.
5: Neuroimmunology Laboratory, Department of Symptom Research, MD Anderson Cancer Center, University of Texas, Houston, Texas 77030.
6: Laboratory of Neuroimmunology, Division of Internal Medicine, and AKavelaars@mdanderson.org.

Articles citing this

Pathophysiology of Chemotherapy-Induced Peripheral Neuropathy. Front Mol Neurosci (2017) 0.76

Articles cited by this

Quantitative assessment of tactile allodynia in the rat paw. J Neurosci Methods (1994) 23.05

Ethical guidelines for investigations of experimental pain in conscious animals. Pain (1983) 17.70

The regulation of IL-10 production by immune cells. Nat Rev Immunol (2010) 9.18

Taxol: a novel investigational antimicrotubule agent. J Natl Cancer Inst (1990) 3.09

Chemotherapy-induced peripheral neuropathy. J Neurol (2002) 3.09

Chemotherapy-induced neuropathy. J Peripher Nerv Syst (2008) 2.97

Studies of peripheral sensory nerves in paclitaxel-induced painful peripheral neuropathy: evidence for mitochondrial dysfunction. Pain (2006) 2.51

Different immune cells mediate mechanical pain hypersensitivity in male and female mice. Nat Neurosci (2015) 2.46

Taxol-induced sensory disturbance is characterized by preferential impairment of myelinated fiber function in cancer patients. Pain (2004) 2.38

Nociceptors are interleukin-1beta sensors. J Neurosci (2008) 2.26

Evidence that spinal astrocytes but not microglia contribute to the pathogenesis of Paclitaxel-induced painful neuropathy. J Pain (2012) 1.93

T-cell infiltration and signaling in the adult dorsal spinal cord is a major contributor to neuropathic pain-like hypersensitivity. J Neurosci (2009) 1.91

Spinal cord Toll-like receptor 4 mediates inflammatory and neuropathic hypersensitivity in male but not female mice. J Neurosci (2011) 1.88

Controlling pathological pain by adenovirally driven spinal production of the anti-inflammatory cytokine, interleukin-10. Eur J Neurosci (2005) 1.73

Exacerbation of facial motoneuron loss after facial nerve transection in severe combined immunodeficient (scid) mice. J Neurosci (1999) 1.70

Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats. Brain Behav Immun (2006) 1.67

Paclitaxel-induced neuropathy. Ann Oncol (1995) 1.65

Paclitaxel in metastatic breast cancer: a trial of two doses by a 3-hour infusion in patients with disease recurrence after prior therapy with anthracyclines. J Natl Cancer Inst (1995) 1.63

Clinical and experimental findings in humans and animals with chemotherapy-induced peripheral neuropathy. Minerva Anestesiol (2006) 1.58

CNS-infiltrating CD4+ T lymphocytes contribute to murine spinal nerve transection-induced neuropathic pain. Eur J Immunol (2008) 1.51

Intraepidermal nerve fiber loss corresponds to the development of taxol-induced hyperalgesia and can be prevented by treatment with minocycline. Pain (2010) 1.51

An evolving cellular pathology occurs in dorsal root ganglia, peripheral nerve and spinal cord following intravenous administration of paclitaxel in the rat. Brain Res (2007) 1.49

CD4+ T, but not CD8+ or B, lymphocytes mediate facial motoneuron survival after facial nerve transection. Brain Behav Immun (2003) 1.46

Neurologic complications of chemotherapy agents. Curr Opin Neurol (2007) 1.39

Direct effect of Taxol on free radical formation and mitochondrial permeability transition. Free Radic Biol Med (2001) 1.38

Chemotherapy-induced neuropathy: A comprehensive survey. Cancer Treat Rev (2014) 1.33

Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis. Pain (2014) 1.33

Cutting edge: programmed death-1 defines CD8+CD122+ T cells as regulatory versus memory T cells. J Immunol (2010) 1.27

Troublesome symptoms in cancer survivors: fatigue, insomnia, neuropathy, and pain. J Clin Oncol (2012) 1.24

The Cancer Chemotherapeutic Paclitaxel Increases Human and Rodent Sensory Neuron Responses to TRPV1 by Activation of TLR4. J Neurosci (2015) 1.24

Toll-like receptor 4 signaling contributes to Paclitaxel-induced peripheral neuropathy. J Pain (2014) 1.22

Chemotherapy-evoked painful peripheral neuropathy. Pain Med (2001) 1.19

Microglial/macrophage GRK2 determines duration of peripheral IL-1beta-induced hyperalgesia: contribution of spinal cord CX3CR1, p38 and IL-1 signaling. Pain (2010) 1.17

GRK2: a novel cell-specific regulator of severity and duration of inflammatory pain. J Neurosci (2010) 1.15

Intrahepatic virus-specific IL-10-producing CD8 T cells prevent liver damage during chronic hepatitis C virus infection. Hepatology (2006) 1.15

The anti-diabetic drug metformin protects against chemotherapy-induced peripheral neuropathy in a mouse model. PLoS One (2014) 1.13

The regulation of IL-10 expression. Curr Top Microbiol Immunol (2014) 1.09

AAV8(gfp) preferentially targets large diameter dorsal root ganglion neurones after both intra-dorsal root ganglion and intrathecal injection. Mol Cell Neurosci (2012) 1.07

Induction of monocyte chemoattractant protein-1 (MCP-1) and its receptor CCR2 in primary sensory neurons contributes to paclitaxel-induced peripheral neuropathy. J Pain (2013) 1.06

Phase I trial of outpatient weekly paclitaxel and concurrent radiation therapy for advanced non-small-cell lung cancer. J Clin Oncol (1994) 1.06

Permeability of injured and intact peripheral nerves and dorsal root ganglia. Anesthesiology (2006) 1.06

Regulatory T cells attenuate neuropathic pain following peripheral nerve injury and experimental autoimmune neuritis. Pain (2012) 1.05

Morphologic features and glial activation in rat oxaliplatin-dependent neuropathic pain. J Pain (2013) 1.05

TNF-α enhances the currents of voltage gated sodium channels in uninjured dorsal root ganglion neurons following motor nerve injury. Exp Neurol (2010) 1.02

Immune-to-brain communication dynamically modulates pain: physiological and pathological consequences. Brain Behav Immun (2005) 1.01

Phase I and pharmacological study of the pulmonary cytotoxin 4-ipomeanol on a single dose schedule in lung cancer patients: hepatotoxicity is dose limiting in humans. Cancer Res (1993) 0.99

Spinal neuroimmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy. Brain Behav Immun (2014) 0.97

Prevention of paclitaxel-induced allodynia by minocycline: Effect on loss of peripheral nerve fibers and infiltration of macrophages in rats. Mol Pain (2010) 0.97

G9a is essential for epigenetic silencing of K(+) channel genes in acute-to-chronic pain transition. Nat Neurosci (2015) 0.94

GRK2 in sensory neurons regulates epinephrine-induced signalling and duration of mechanical hyperalgesia. Pain (2011) 0.94

Mechanisms of chemotherapy-induced behavioral toxicities. Front Neurosci (2015) 0.92

Astrocytes, but not microglia, are activated in oxaliplatin and bortezomib-induced peripheral neuropathy in the rat. Neuroscience (2014) 0.91

Interleukin-10 down-regulates voltage gated sodium channels in rat dorsal root ganglion neurons. Exp Neurol (2013) 0.90

Snake venom components enhance pain upon subcutaneous injection: an initial examination of spinal cord mediators. Pain (2004) 0.89

Enhanced excitability of primary sensory neurons and altered gene expression of neuronal ion channels in dorsal root ganglion in paclitaxel-induced peripheral neuropathy. Anesthesiology (2014) 0.89

CX3CL1-mediated macrophage activation contributed to paclitaxel-induced DRG neuronal apoptosis and painful peripheral neuropathy. Brain Behav Immun (2014) 0.86

A3 adenosine receptor agonist prevents the development of paclitaxel-induced neuropathic pain by modulating spinal glial-restricted redox-dependent signaling pathways. Pain (2014) 0.86

Dorsal Root Ganglion Infiltration by Macrophages Contributes to Paclitaxel Chemotherapy-Induced Peripheral Neuropathy. J Pain (2016) 0.85

MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4. J Clin Invest (2015) 0.84

Neuroantigen-specific autoregulatory CD8+ T cells inhibit autoimmune demyelination through modulation of dendritic cell function. PLoS One (2014) 0.83

Prevention of chemotherapy-induced peripheral neuropathy by the small-molecule inhibitor pifithrin-μ. Pain (2015) 0.83

Depletion of Foxp3+ regulatory T cells increases severity of mechanical allodynia and significantly alters systemic cytokine levels following peripheral nerve injury. Cytokine (2014) 0.80

Intrathecal administration of IGF-I by AAVrh10 improves sensory and motor deficits in a mouse model of diabetic neuropathy. Mol Ther Methods Clin Dev (2014) 0.77

Interleukin-10 Protection against Lipopolysaccharide-Induced Neuro-Inflammation and Neurotoxicity in Ventral Mesencephalic Cultures. Int J Mol Sci (2015) 0.76

IL4-10 Fusion Protein Is a Novel Drug to Treat Persistent Inflammatory Pain. J Neurosci (2016) 0.76

Articles by these authors

IL4-10 Fusion Protein Is a Novel Drug to Treat Persistent Inflammatory Pain. J Neurosci (2016) 0.76