Published in Mol Biol Cell on November 16, 2016
A core function for p120-catenin in cadherin turnover. J Cell Biol (2003) 4.85
A repeating amino acid motif shared by proteins with diverse cellular roles. Cell (1994) 4.56
The juxtamembrane region of the cadherin cytoplasmic tail supports lateral clustering, adhesive strengthening, and interaction with p120ctn. J Cell Biol (1998) 4.38
Micromotion of mammalian cells measured electrically. Proc Natl Acad Sci U S A (1991) 3.51
Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells. J Cell Biol (2003) 3.39
Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion. Cell (2010) 2.83
ICAM-1-mediated, Src- and Pyk2-dependent vascular endothelial cadherin tyrosine phosphorylation is required for leukocyte transendothelial migration. J Immunol (2007) 2.66
Tyrosine phosphorylation of VE-cadherin prevents binding of p120- and beta-catenin and maintains the cellular mesenchymal state. J Biol Chem (2005) 2.59
Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction. J Clin Invest (2004) 2.48
p120-Catenin regulates clathrin-dependent endocytosis of VE-cadherin. Mol Biol Cell (2005) 2.37
Leukocyte extravasation and vascular permeability are each controlled in vivo by different tyrosine residues of VE-cadherin. Nat Immunol (2014) 2.10
p120 catenin associates with kinesin and facilitates the transport of cadherin-catenin complexes to intercellular junctions. J Cell Biol (2003) 2.02
Cell confluence regulates tyrosine phosphorylation of adherens junction components in endothelial cells. J Cell Sci (1997) 2.01
Interleukin receptor activates a MYD88-ARNO-ARF6 cascade to disrupt vascular stability. Nature (2012) 1.96
Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis. Biochim Biophys Acta (2007) 1.87
VEGF-induced vascular permeability is mediated by FAK. Dev Cell (2012) 1.85
Phosphorylation of VE-cadherin is modulated by haemodynamic forces and contributes to the regulation of vascular permeability in vivo. Nat Commun (2012) 1.78
Phosphorylation of vascular endothelial cadherin controls lymphocyte emigration. J Cell Sci (2008) 1.74
An optimized three-dimensional in vitro model for the analysis of angiogenesis. Methods Enzymol (2008) 1.73
VE-cadherin: adhesion at arm's length. Am J Physiol Cell Physiol (2004) 1.73
The regulation of vascular endothelial growth factor-induced microvascular permeability requires Rac and reactive oxygen species. J Biol Chem (2009) 1.69
VE-cadherin-p120 interaction is required for maintenance of endothelial barrier function. Am J Physiol Lung Cell Mol Physiol (2003) 1.50
p120-Catenin regulates leukocyte transmigration through an effect on VE-cadherin phosphorylation. Blood (2008) 1.48
p120-catenin binding masks an endocytic signal conserved in classical cadherins. J Cell Biol (2012) 1.48
Src-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers. J Biol Chem (2010) 1.35
p120-catenin inhibits VE-cadherin internalization through a Rho-independent mechanism. Mol Biol Cell (2009) 1.32
Phosphorylation of VE-cadherin controls endothelial phenotypes via p120-catenin coupling and Rac1 activation. Am J Physiol Heart Circ Physiol (2010) 1.15
VE-cadherin and beta-catenin binding dynamics during histamine-induced endothelial hyperpermeability. Am J Physiol Cell Physiol (2008) 1.09
PKCα activation of p120-catenin serine 879 phospho-switch disassembles VE-cadherin junctions and disrupts vascular integrity. Circ Res (2012) 1.03
Adenovirus-mediated overexpression of C-terminal Src kinase (Csk) in type I astrocytes interferes with cell spreading and attachment to fibronectin. Correlation with tyrosine phosphorylations of paxillin and FAK. J Biol Chem (1999) 0.99
p120 regulates endothelial permeability independently of its NH2 terminus and Rho binding. Am J Physiol Heart Circ Physiol (2010) 0.98
Interaction of p190RhoGAP with C-terminal domain of p120-catenin modulates endothelial cytoskeleton and permeability. J Biol Chem (2013) 0.95
Evidence of a common mechanism of disassembly of adherens junctions through Gα13 targeting of VE-cadherin. J Exp Med (2014) 0.94
The tyrosine phosphatase SHP2 regulates recovery of endothelial adherens junctions through control of β-catenin phosphorylation. Mol Biol Cell (2012) 0.94
An octapeptide in the juxtamembrane domain of VE-cadherin is important for p120ctn binding and cell proliferation. Exp Cell Res (2002) 0.93
Characterization of cadherin-4 and cadherin-5 reveals new aspects of cadherins. J Cell Sci (1994) 0.91
Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin. J Exp Med (2015) 0.87
p120-Catenin prevents neutrophil transmigration independently of RhoA inhibition by impairing Src dependent VE-cadherin phosphorylation. Am J Physiol Cell Physiol (2012) 0.85
Regulation of Endothelial Adherens Junctions by Tyrosine Phosphorylation. Mediators Inflamm (2015) 0.78
Src Family Kinases Modulate the Loss of Endothelial Barrier Function in Response to TNF-α: Crosstalk with p38 Signaling. PLoS One (2016) 0.76