Published in J Biol Chem on May 07, 2013
Rac1 functions as a reversible tension modulator to stabilize VE-cadherin trans-interaction. J Cell Biol (2015) 1.04
Mechanisms regulating endothelial permeability. Pulm Circ (2014) 0.99
RhoGTPases, actomyosin signaling and regulation of the epithelial Apical Junctional Complex. Semin Cell Dev Biol (2014) 0.95
Cytoskeletal mechanisms regulating vascular endothelial barrier function in response to acute lung injury. Tissue Barriers (2015) 0.94
Simvastatin alleviates hyperpermeability of glomerular endothelial cells in early-stage diabetic nephropathy by inhibition of RhoA/ROCK1. PLoS One (2013) 0.87
IQGAP1 regulates endothelial barrier function via EB1-cortactin cross talk. Mol Cell Biol (2014) 0.86
Asef controls vascular endothelial permeability and barrier recovery in the lung. Mol Biol Cell (2014) 0.86
Rho GAPs and GEFs: controling switches in endothelial cell adhesion. Cell Adh Migr (2014) 0.82
Control of vascular permeability by adhesion molecules. Tissue Barriers (2015) 0.81
DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia. Mol Biol Cell (2014) 0.81
p120catenin alteration in cancer and its role in tumour invasion. Philos Trans R Soc Lond B Biol Sci (2013) 0.81
p120-catenin controls contractility along the vertical axis of epithelial lateral membranes. J Cell Sci (2015) 0.81
PDCD10 (CCM3) regulates brain endothelial barrier integrity in cerebral cavernous malformation type 3: role of CCM3-ERK1/2-cortactin cross-talk. Acta Neuropathol (2015) 0.77
Phosphorylation and isoform use in p120-catenin during development and tumorigenesis. Biochim Biophys Acta (2015) 0.77
Rho GTPases and actomyosin: Partners in regulating epithelial cell-cell junction structure and function. Exp Cell Res (2017) 0.76
CD148 tyrosine phosphatase promotes cadherin cell adhesion. PLoS One (2014) 0.76
Roles of the novel coiled-coil protein Rng10 in septum formation during fission yeast cytokinesis. Mol Biol Cell (2016) 0.76
Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability. Circ Res (2017) 0.76
Endothelial Cell Signaling and Ventilator-Induced Lung Injury (VILI): Molecular Mechanisms, Genomic Analyses & Therapeutic Targets. Am J Physiol Lung Cell Mol Physiol (2016) 0.75
Regulation of endothelial barrier function by p120-catenin·VE-Cadherin interaction. Mol Biol Cell (2016) 0.75
Getting to the core of cadherin complex function in Caenorhabditis elegans. F1000Res (2015) 0.75
Role of Cingulin in Agonist-induced Vascular Endothelial Permeability. J Biol Chem (2016) 0.75
A core function for p120-catenin in cadherin turnover. J Cell Biol (2003) 4.85
p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. Cell (2006) 4.24
A novel role for p120 catenin in E-cadherin function. J Cell Biol (2002) 4.01
Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion. J Cell Biol (2000) 3.88
p120 catenin regulates the actin cytoskeleton via Rho family GTPases. J Cell Biol (2000) 3.60
Inhibition of RhoA by p120 catenin. Nat Cell Biol (2000) 3.33
The catenin p120(ctn) interacts with Kaiso, a novel BTB/POZ domain zinc finger transcription factor. Mol Cell Biol (1999) 3.02
Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion. Cell (2010) 2.83
p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell-cell contact formation and regulation of cell locomotion. J Cell Sci (2001) 2.40
Regulation of Rho GTPases by p120-catenin. Curr Opin Cell Biol (2001) 2.34
Emerging roles for p120-catenin in cell adhesion and cancer. Oncogene (2004) 2.12
Role of Rho GTPases in thrombin-induced lung vascular endothelial cells barrier dysfunction. Microvasc Res (2004) 2.07
p120-catenin: Past and present. Biochim Biophys Acta (2006) 1.98
The tyrosine kinase substrate p120cas binds directly to E-cadherin but not to the adenomatous polyposis coli protein or alpha-catenin. Mol Cell Biol (1995) 1.96
Epoxycyclopentenone-containing oxidized phospholipids restore endothelial barrier function via Cdc42 and Rac. Circ Res (2004) 1.88
A p120 catenin isoform switch affects Rho activity, induces tumor cell invasion, and predicts metastatic disease. J Biol Chem (2008) 1.87
Regulation of Rho family GTPases by cell-cell and cell-matrix adhesion. Biol Res (2002) 1.63
Specific phosphorylation of p120-catenin regulatory domain differently modulates its binding to RhoA. Mol Cell Biol (2006) 1.50
p120 catenin is essential for mesenchymal cadherin-mediated regulation of cell motility and invasiveness. J Cell Biol (2006) 1.50
Cadherin engagement inhibits RhoA via p190RhoGAP. J Biol Chem (2003) 1.50
Role of p120-catenin in cadherin trafficking. Biochim Biophys Acta (2006) 1.44
p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice. J Clin Invest (2010) 1.41
HER2/ErbB2-induced breast cancer cell migration and invasion require p120 catenin activation of Rac1 and Cdc42. J Biol Chem (2010) 1.24
Innate immune function of the adherens junction protein p120-catenin in endothelial response to endotoxin. J Immunol (2011) 1.23
Magnitude-dependent effects of cyclic stretch on HGF- and VEGF-induced pulmonary endothelial remodeling and barrier regulation. Am J Physiol Lung Cell Mol Physiol (2008) 1.22
Protein kinase C modifications of VE-cadherin, p120, and beta-catenin contribute to endothelial barrier dysregulation induced by thrombin. Am J Physiol Lung Cell Mol Physiol (2003) 1.19
p120-Catenin is required for mouse vascular development. Circ Res (2010) 1.16
Phosphorylation of VE-cadherin controls endothelial phenotypes via p120-catenin coupling and Rac1 activation. Am J Physiol Heart Circ Physiol (2010) 1.15
Traffic control: p120-catenin acts as a gatekeeper to control the fate of classical cadherins in mammalian cells. J Cell Biol (2003) 1.09
p190RhoGAP mediates protective effects of oxidized phospholipids in the models of ventilator-induced lung injury. Exp Cell Res (2010) 1.08
Association between adherens junctions and tight junctions via Rap1 promotes barrier protective effects of oxidized phospholipids. J Cell Physiol (2011) 1.05
An FF domain-dependent protein interaction mediates a signaling pathway for growth factor-induced gene expression. Mol Cell (2005) 1.05
The regulatory or phosphorylation domain of p120 catenin controls E-cadherin dynamics at the plasma membrane. Exp Cell Res (2007) 1.04
VE-cadherin trans-interactions modulate Rac activation and enhancement of lung endothelial barrier by iloprost. J Cell Physiol (2012) 1.00
The molecular evolution of the p120-catenin subfamily and its functional associations. PLoS One (2010) 0.98
Adenoma formation following limited ablation of p120-catenin in the mouse intestine. PLoS One (2011) 0.98
Differential regulation of endothelial cell permeability by high and low doses of oxidized 1-palmitoyl-2-arachidonyl-sn-glycero-3-phosphocholine. Am J Respir Cell Mol Biol (2011) 0.95
Unraveling the distinct distributions of VE- and N-cadherins in endothelial cells: a key role for p120-catenin. Exp Cell Res (2010) 0.90
p120-Catenin is essential for N-cadherin-mediated formation of proper junctional structure, thereby establishing cell polarity in epithelial cells. Cell Struct Funct (2010) 0.78
A core function for p120-catenin in cadherin turnover. J Cell Biol (2003) 4.85
p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho. Cell (2006) 4.24
A novel role for p120 catenin in E-cadherin function. J Cell Biol (2002) 4.01
Magnitude-dependent regulation of pulmonary endothelial cell barrier function by cyclic stretch. Am J Physiol Lung Cell Mol Physiol (2003) 2.89
Retracted G alpha(q)-mediated activation of GRK2 by mechanical stretch in cardiac myocytes: the role of protein kinase C. J Biol Chem (2010) 2.81
p120-catenin mediates inflammatory responses in the skin. Cell (2006) 2.66
N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso. Mol Cell (2003) 2.47
Pulmonary endothelial cell barrier enhancement by sphingosine 1-phosphate: roles for cortactin and myosin light chain kinase. J Biol Chem (2004) 2.44
Differential regulation of pulmonary endothelial monolayer integrity by varying degrees of cyclic stretch. Am J Pathol (2006) 2.25
Induction of cellular antioxidant defense by amifostine improves ventilator-induced lung injury. Crit Care Med (2011) 2.24
Cholinergic modulation of Kir2 channels selectively elevates dendritic excitability in striatopallidal neurons. Nat Neurosci (2007) 2.15
Deletion of p120-catenin results in a tumor microenvironment with inflammation and cancer that establishes it as a tumor suppressor gene. Cancer Cell (2011) 2.10
Role of Rho GTPases in thrombin-induced lung vascular endothelial cells barrier dysfunction. Microvasc Res (2004) 2.07
Generation and biological activities of oxidized phospholipids. Antioxid Redox Signal (2010) 2.04
The p120(ctn)-binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG dinucleotides. Nucleic Acids Res (2002) 2.02
Novel role of microtubules in thrombin-induced endothelial barrier dysfunction. FASEB J (2004) 1.98
Epoxycyclopentenone-containing oxidized phospholipids restore endothelial barrier function via Cdc42 and Rac. Circ Res (2004) 1.88
Prostaglandins PGE(2) and PGI(2) promote endothelial barrier enhancement via PKA- and Epac1/Rap1-dependent Rac activation. Exp Cell Res (2007) 1.83
GEF-H1 is involved in agonist-induced human pulmonary endothelial barrier dysfunction. Am J Physiol Lung Cell Mol Physiol (2005) 1.81
Altered expression of the catenin p120 in human cancer: implications for tumor progression. Differentiation (2002) 1.80
SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1. Mol Cell Biol (2009) 1.79
Shear stress-mediated cytoskeletal remodeling and cortactin translocation in pulmonary endothelial cells. Am J Respir Cell Mol Biol (2002) 1.78
Blocked acinar development, E-cadherin reduction, and intraepithelial neoplasia upon ablation of p120-catenin in the mouse salivary gland. Dev Cell (2006) 1.77
Measurement of local permeability at subcellular level in cell models of agonist- and ventilator-induced lung injury. Lab Invest (2012) 1.74
Focal adhesions: paradigm for a signaling nexus. Circ Res (2006) 1.73
Rationally improving LOV domain-based photoswitches. Nat Methods (2010) 1.72
Microtubule disassembly induces cytoskeletal remodeling and lung vascular barrier dysfunction: role of Rho-dependent mechanisms. J Cell Physiol (2004) 1.70
Akt-mediated transactivation of the S1P1 receptor in caveolin-enriched microdomains regulates endothelial barrier enhancement by oxidized phospholipids. Circ Res (2009) 1.64
Differential effects of shear stress and cyclic stretch on focal adhesion remodeling, site-specific FAK phosphorylation, and small GTPases in human lung endothelial cells. Exp Cell Res (2004) 1.63
Cytoskeletal activation and altered gene expression in endothelial barrier regulation by simvastatin. Am J Respir Cell Mol Biol (2003) 1.56
S1P induces FA remodeling in human pulmonary endothelial cells: role of Rac, GIT1, FAK, and paxillin. J Appl Physiol (1985) (2002) 1.52
Involvement of microtubules and Rho pathway in TGF-beta1-induced lung vascular barrier dysfunction. J Cell Physiol (2005) 1.50
Involvement of site-specific FAK phosphorylation in sphingosine-1 phosphate- and thrombin-induced focal adhesion remodeling: role of Src and GIT. FASEB J (2003) 1.48
Mechanotransduction by GEF-H1 as a novel mechanism of ventilator-induced vascular endothelial permeability. Am J Physiol Lung Cell Mol Physiol (2010) 1.46
A novel interaction between kinesin and p120 modulates p120 localization and function. J Biol Chem (2003) 1.43
Epac/Rap and PKA are novel mechanisms of ANP-induced Rac-mediated pulmonary endothelial barrier protection. J Cell Physiol (2008) 1.42
Mechanical stress activates xanthine oxidoreductase through MAP kinase-dependent pathways. Am J Physiol Lung Cell Mol Physiol (2006) 1.42
Role of phospholipid oxidation products in atherosclerosis. Circ Res (2012) 1.41
p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice. J Clin Invest (2010) 1.41
HGF attenuates thrombin-induced endothelial permeability by Tiam1-mediated activation of the Rac pathway and by Tiam1/Rac-dependent inhibition of the Rho pathway. FASEB J (2007) 1.39
Paxillin-beta-catenin interactions are involved in Rac/Cdc42-mediated endothelial barrier-protective response to oxidized phospholipids. Am J Physiol Lung Cell Mol Physiol (2007) 1.37
Protecting your tail: regulation of cadherin degradation by p120-catenin. Curr Opin Cell Biol (2004) 1.37
Oxidized phospholipids reduce vascular leak and inflammation in rat model of acute lung injury. Am J Respir Crit Care Med (2006) 1.36
Novel interaction of cortactin with endothelial cell myosin light chain kinase. Biochem Biophys Res Commun (2002) 1.34
Polar head groups are important for barrier-protective effects of oxidized phospholipids on pulmonary endothelium. Am J Physiol Lung Cell Mol Physiol (2006) 1.31
Methylation-associated silencing of the thrombospondin-1 gene in human neuroblastoma. Cancer Res (2003) 1.28
EGFR signaling to p120-catenin through phosphorylation at Y228. J Cell Sci (2004) 1.25
Oxidized phospholipids reduce ventilator-induced vascular leak and inflammation in vivo. Crit Care (2008) 1.23
Integrated biochemical and mechanical signals regulate multifaceted human embryonic stem cell functions. J Cell Biol (2010) 1.22
Magnitude-dependent effects of cyclic stretch on HGF- and VEGF-induced pulmonary endothelial remodeling and barrier regulation. Am J Physiol Lung Cell Mol Physiol (2008) 1.22
Endothelial permeability is controlled by spatially defined cytoskeletal mechanics: atomic force microscopy force mapping of pulmonary endothelial monolayer. Nanomedicine (2008) 1.21
SPARC expression is associated with impaired tumor growth, inhibited angiogenesis and changes in the extracellular matrix. Int J Cancer (2006) 1.20
Cell cycle-dependent regulation of a human DNA helicase that localizes in DNA damage foci. Mol Biol Cell (2004) 1.20
Adhesion-associated and PKC-modulated changes in serine/threonine phosphorylation of p120-catenin. Biochemistry (2003) 1.19
Differential regulation of human lung epithelial and endothelial barrier function by thrombin. Am J Respir Cell Mol Biol (2004) 1.19
ANP attenuates inflammatory signaling and Rho pathway of lung endothelial permeability induced by LPS and TNFalpha. Microvasc Res (2009) 1.18
MAP kinases in lung endothelial permeability induced by microtubule disassembly. Am J Physiol Lung Cell Mol Physiol (2005) 1.18
Atomic structures of peptide self-assembly mimics. Proc Natl Acad Sci U S A (2006) 1.17
Paxillin is involved in the differential regulation of endothelial barrier by HGF and VEGF. Am J Respir Cell Mol Biol (2008) 1.17
Regulation of p120-catenin nucleocytoplasmic shuttling activity. J Cell Sci (2003) 1.17
p120-Catenin is required for mouse vascular development. Circ Res (2010) 1.16
Rac GTPase is a hub for protein kinase A and Epac signaling in endothelial barrier protection by cAMP. Microvasc Res (2009) 1.16
Thrombospondin-1 peptide ABT-510 combined with valproic acid is an effective antiangiogenesis strategy in neuroblastoma. Cancer Res (2007) 1.16
Regulation of the micromechanical properties of pulmonary endothelium by S1P and thrombin: role of cortactin. Biophys J (2008) 1.16
Enhanced interaction between focal adhesion and adherens junction proteins: involvement in sphingosine 1-phosphate-induced endothelial barrier enhancement. Microvasc Res (2009) 1.16
p120 and Kaiso regulate Helicobacter pylori-induced expression of matrix metalloproteinase-7. Mol Biol Cell (2008) 1.15
Stimulation of Rho signaling by pathologic mechanical stretch is a "second hit" to Rho-independent lung injury induced by IL-6. Am J Physiol Lung Cell Mol Physiol (2012) 1.15
Association of epigenetic inactivation of RASSF1A with poor outcome in human neuroblastoma. Clin Cancer Res (2004) 1.14
Methylation of CASP8, DCR2, and HIN-1 in neuroblastoma is associated with poor outcome. Clin Cancer Res (2007) 1.13
An essential role for p120-catenin in Src- and Rac1-mediated anchorage-independent cell growth. J Cell Biol (2009) 1.13
Microenvironmental independence associated with tumor progression. Cancer Res (2009) 1.13
Tiam1 and betaPIX mediate Rac-dependent endothelial barrier protective response to oxidized phospholipids. J Cell Physiol (2007) 1.12
Oxidative stress contributes to lung injury and barrier dysfunction via microtubule destabilization. Am J Respir Cell Mol Biol (2012) 1.11
Atomic-resolution crystal structure of Borrelia burgdorferi outer surface protein A via surface engineering. Protein Sci (2006) 1.10
Atrial natriuretic peptide attenuates LPS-induced lung vascular leak: role of PAK1. Am J Physiol Lung Cell Mol Physiol (2010) 1.10
ReCLIP (reversible cross-link immuno-precipitation): an efficient method for interrogation of labile protein complexes. PLoS One (2011) 1.09
Association of Rho-associated protein kinase 1 with E-cadherin complexes is mediated by p120-catenin. Mol Biol Cell (2011) 1.08
Conformational heterogeneity of an equilibrium folding intermediate quantified and mapped by scanning mutagenesis. J Mol Biol (2004) 1.08
p190RhoGAP mediates protective effects of oxidized phospholipids in the models of ventilator-induced lung injury. Exp Cell Res (2010) 1.08
Signaling pathways involved in OxPAPC-induced pulmonary endothelial barrier protection. Microvasc Res (2007) 1.08
Targeted p120-catenin ablation disrupts dental enamel development. PLoS One (2010) 1.06
Expression and nuclear location of the transcriptional repressor Kaiso is regulated by the tumor microenvironment. Cancer Res (2005) 1.06
Association between adherens junctions and tight junctions via Rap1 promotes barrier protective effects of oxidized phospholipids. J Cell Physiol (2011) 1.05
A p120-catenin-CK1epsilon complex regulates Wnt signaling. J Cell Sci (2010) 1.05
ALK5 and Smad4 are involved in TGF-beta1-induced pulmonary endothelial permeability. FEBS Lett (2005) 1.04
The regulatory or phosphorylation domain of p120 catenin controls E-cadherin dynamics at the plasma membrane. Exp Cell Res (2007) 1.04
Sphingolipid-mediated inhibition of apoptotic cell clearance by alveolar macrophages. J Biol Chem (2010) 1.04
Anti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors. Mol Cancer (2010) 1.03
EGFR-activated signaling and actin remodeling regulate cyclic stretch-induced NRF2-ARE activation. Am J Respir Cell Mol Biol (2006) 1.02
Cross talk between paxillin and Rac is critical for mediation of barrier-protective effects by oxidized phospholipids. Am J Physiol Lung Cell Mol Physiol (2008) 1.01
Regulation of cochlear convergent extension by the vertebrate planar cell polarity pathway is dependent on p120-catenin. Development (2012) 1.00