Published in Cancer Res on November 21, 2016
Epigenetic regulation by the menin pathway. Endocr Relat Cancer (2017) 0.75
Twenty years of menin: emerging opportunities for restoration of transcription in MEN1. Endocr Relat Cancer (2017) 0.75
DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. Science (2011) 10.26
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres. Proc Natl Acad Sci U S A (2010) 4.73
Altered telomeres in tumors with ATRX and DAXX mutations. Science (2011) 4.60
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. Genes Dev (2010) 4.00
Loss of E-cadherin and cytoplasmic-nuclear expression of beta-catenin are the most useful immunoprofiles in the diagnosis of solid-pseudopapillary neoplasm of the pancreas. Hum Pathol (2007) 2.67
Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c. Proc Natl Acad Sci U S A (2005) 2.59
A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors. Proc Natl Acad Sci U S A (2001) 2.57
Daxx and histone deacetylase II associate with chromatin through an interaction with core histones and the chromatin-associated protein Dek. J Cell Sci (2002) 2.30
Inherited pancreatic endocrine tumor syndromes: advances in molecular pathogenesis, diagnosis, management, and controversies. Cancer (2008) 2.11
A novel transcription regulatory complex containing death domain-associated protein and the ATR-X syndrome protein. J Biol Chem (2004) 1.98
Molecular genetics of multiple endocrine neoplasia types 1 and 2. Nat Rev Cancer (2005) 1.87
The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression. Proc Natl Acad Sci U S A (2006) 1.67
DAXX envelops a histone H3.3-H4 dimer for H3.3-specific recognition. Nature (2012) 1.65
The same pocket in menin binds both MLL and JUND but has opposite effects on transcription. Nature (2012) 1.62
Molecular basis of the mixed lineage leukemia-menin interaction: implications for targeting mixed lineage leukemias. J Biol Chem (2010) 1.56
Pancreatic beta-cell-specific ablation of the multiple endocrine neoplasia type 1 (MEN1) gene causes full penetrance of insulinoma development in mice. Cancer Res (2003) 1.54
Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors. Gastroenterology (2013) 1.39
Multiple endocrine neoplasia type 1 (MEN1). Best Pract Res Clin Endocrinol Metab (2010) 1.37
Mutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cells. Cancer Res (2006) 1.36
Neuroendocrine neoplasms of the gut and pancreas: new insights. Nat Rev Endocrinol (2011) 1.35
Structural insights into inhibition of the bivalent menin-MLL interaction by small molecules in leukemia. Blood (2012) 1.31
Multiple endocrine neoplasia type 1. Endocr Relat Cancer (1999) 1.21
Targeted therapies in neuroendocrine tumors (NET): clinical trial challenges and lessons learned. Oncologist (2013) 1.09
Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors. Mod Pathol (2012) 1.06
Suppression of lung adenocarcinoma through menin and polycomb gene-mediated repression of growth factor pleiotrophin. Oncogene (2009) 1.05
Menin promotes hepatocellular carcinogenesis and epigenetically up-regulates Yap1 transcription. Proc Natl Acad Sci U S A (2013) 1.03
CD10 enhances metastasis of colorectal cancer by abrogating the anti-tumoural effect of methionine-enkephalin in the liver. Gut (2009) 1.01
Tumor suppressor menin regulates expression of insulin-like growth factor binding protein 2. Endocrinology (2004) 1.01
Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome. Cancer Res (2013) 0.97
Somatic mutations of multiple endocrine neoplasia type 1 gene in the sporadic endocrine tumors. Lab Invest (1998) 0.95
The Expression of CD10 and CD15 Is Progressively Increased during Colorectal Cancer Development. Korean J Pathol (2013) 0.95
Multi-institutional study of risk factors of liver metastasis from colorectal cancer: correlation with CD10 expression. Int J Colorectal Dis (2010) 0.92
Characterization of the release of cholecystokinin from a murine neuroendocrine tumor cell line, STC-1. Biochim Biophys Acta (1994) 0.90
Menin mediates epigenetic regulation via histone H3 lysine 9 methylation. Cell Death Dis (2013) 0.89
CD10 expression in pancreatic endocrine tumors: correlation with prognostic factors and survival. Hum Pathol (2006) 0.86
An Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc Axis. Cancer Cell (2015) 0.84
SUMO modification of menin. Am J Cancer Res (2013) 0.78
Death domain-associated protein 6 (Daxx) selectively represses IL-6 transcription through histone deacetylase 1 (HDAC1)-mediated histone deacetylation in macrophages. J Biol Chem (2014) 0.78
[Membrane metalloendopeptidase (CD10/CALLA): distribution, physiologic and pathophysiologic functions and its inhibitors]. Lijec Vjesn (1998) 0.77
CK19 and CD10 expression in pancreatic neuroendocrine tumors diagnosed by endoscopic ultrasound-guided fine-needle aspiration cytology. Cancer (2009) 0.77
Relationship between enkephalinase inhibition of thiorphan in vivo and its analgesic activity. J Pharmacobiodyn (1985) 0.76