Transcriptional Regulation of Notch1 Expression by Nkx6.1 in Neural Stem/Progenitor Cells during Ventral Spinal Cord Development.

PubWeight™: 0.75‹?›

🔗 View Article (PMID 27924849)

Published in Sci Rep on December 07, 2016

Authors

Ying Li1, Evangeline Tzatzalos1, Kelvin Y Kwan2, Martin Grumet2, Li Cai1

Author Affiliations

1: Department of Biomedical Engineering, Rutgers University, 599 Taylor Road, Piscataway, NJ 08854, USA.
2: W.M. Keck Center for Collaborative Neuroscience, Department of Cell Biology and Neuroscience, Rutgers University, 604 Allison Road, Piscataway, NJ 08854, USA.

Articles cited by this

A series of normal stages in the development of the chick embryo. J Morphol (1951) 17.89

TRANSFAC: an integrated system for gene expression regulation. Nucleic Acids Res (2000) 15.70

In vivo enhancer analysis of human conserved non-coding sequences. Nature (2006) 10.60

Neuronal specification in the spinal cord: inductive signals and transcriptional codes. Nat Rev Genet (2000) 9.54

Identification of a neural stem cell in the adult mammalian central nervous system. Cell (1999) 6.53

A homeodomain protein code specifies progenitor cell identity and neuronal fate in the ventral neural tube. Cell (2000) 5.49

A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol (2011) 4.84

Attenuation of green fluorescent protein half-life in mammalian cells. Protein Eng (1999) 3.65

Spinal cord injury reveals multilineage differentiation of ependymal cells. PLoS Biol (2008) 2.80

The astrocyte odyssey. Prog Neurobiol (2008) 2.58

Origin of new glial cells in intact and injured adult spinal cord. Cell Stem Cell (2010) 2.23

Diversity and pattern in the developing spinal cord. Science (1996) 2.18

Notch in the vertebrate nervous system: an old dog with new tricks. Neuron (2011) 2.14

Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development (1992) 1.99

Nuclear Notch1 signaling and the regulation of dendritic development. Nat Neurosci (2000) 1.87

Regulation of the neural patterning activity of sonic hedgehog by secreted BMP inhibitors expressed by notochord and somites. Development (2000) 1.77

Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates. Genes Dev (2000) 1.77

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway. Development (1997) 1.74

Fate of endogenous stem/progenitor cells following spinal cord injury. J Comp Neurol (2006) 1.73

Loss of notch activity in the developing central nervous system leads to increased cell death. Dev Neurosci (2006) 1.65

Ascl1 and Gsh1/2 control inhibitory and excitatory cell fate in spinal sensory interneurons. Nat Neurosci (2006) 1.61

Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process. Development (2003) 1.61

SnapShot: spinal cord development. Cell (2011) 1.56

Notch and MAML signaling drives Scl-dependent interneuron diversity in the spinal cord. Neuron (2007) 1.52

In vivo characterization of a vertebrate ultraconserved enhancer. Genomics (2005) 1.49

Introduction of DNA into chick embryos by in ovo electroporation. Methods (2001) 1.47

Gsh-1: a novel murine homeobox gene expressed in the central nervous system. Dev Dyn (1995) 1.37

A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool. Development (2007) 1.37

Synergistic binding of transcription factors to cell-specific enhancers programs motor neuron identity. Nat Neurosci (2013) 1.36

Notch signaling is required to maintain all neural stem cell populations--irrespective of spatial or temporal niche. Dev Neurosci (2006) 1.32

Notch1 signaling influences v2 interneuron and motor neuron development in the spinal cord. Dev Neurosci (2006) 1.17

Selection of differentiating cells by different levels of delta-like 1 among neural precursor cells in the developing mouse telencephalon. Development (2008) 1.07

Active 3-D microscaffold system with fluid perfusion for culturing in vitro neuronal networks. Lab Chip (2007) 1.03

Molecular mapping of the origin of postnatal spinal cord ependymal cells: evidence that adult ependymal cells are derived from Nkx6.1+ ventral neural progenitor cells. J Comp Neurol (2003) 0.97

Neural stem cells in the adult spinal cord. Exp Neurol (2013) 0.93

Cux2 functions downstream of Notch signaling to regulate dorsal interneuron formation in the spinal cord. Development (2009) 0.91

Asymmetric activation of Dll4-Notch signaling by Foxn4 and proneural factors activates BMP/TGFβ signaling to specify V2b interneurons in the spinal cord. Development (2013) 0.89

A direct fate exclusion mechanism by Sonic hedgehog-regulated transcriptional repressors. Development (2015) 0.83

Different combinations of Notch ligands and receptors regulate V2 interneuron progenitor proliferation and V2a/V2b cell fate determination. Dev Biol (2014) 0.81

The late and dual origin of cerebrospinal fluid-contacting neurons in the mouse spinal cord. Development (2016) 0.78

A cis-element in the Notch1 locus is involved in the regulation of gene expression in interneuron progenitors. Dev Biol (2012) 0.77