Published in Oncotarget on December 21, 2016
BARD1 serum autoantibodies for the detection of lung cancer. PLoS One (2017) 0.75
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. Genes Dev (2001) 15.97
Shelterin: the protein complex that shapes and safeguards human telomeres. Genes Dev (2005) 15.19
TRF2 protects human telomeres from end-to-end fusions. Cell (1998) 10.13
A minimal peptide substrate in biotin holoenzyme synthetase-catalyzed biotinylation. Protein Sci (1999) 6.05
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell (1997) 5.92
The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation. J Biol Chem (2001) 4.51
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex. Nat Struct Biol (2001) 4.15
53BP1 regulates DSB repair using Rif1 to control 5' end resection. Science (2013) 4.00
The BRCA1/BARD1 heterodimer modulates ran-dependent mitotic spindle assembly. Cell (2006) 3.46
Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins. Nat Rev Cancer (2011) 2.66
Interactions between BRCT repeats and phosphoproteins: tangled up in two. Trends Biochem Sci (2004) 2.63
Common variations in BARD1 influence susceptibility to high-risk neuroblastoma. Nat Genet (2009) 2.47
Attributes of short linear motifs. Mol Biosyst (2011) 2.32
The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators. Oncogene (1999) 2.15
Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein. J Biol Chem (2002) 2.08
The BARD1-CstF-50 interaction links mRNA 3' end formation to DNA damage and tumor suppression. Cell (2001) 1.95
The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres. EMBO J (2010) 1.83
The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage. J Cell Biol (2010) 1.82
Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50. Science (1999) 1.67
The multiple nuclear functions of BRCA1: transcription, ubiquitination and DNA repair. Curr Opin Cell Biol (2003) 1.65
Phenotype restricted genome-wide association study using a gene-centric approach identifies three low-risk neuroblastoma susceptibility Loci. PLoS Genet (2011) 1.57
The BRCA1 C-terminal domain: structure and function. Mutat Res (2000) 1.57
Function of BRCA1 in the DNA damage response is mediated by ADP-ribosylation. Cancer Cell (2013) 1.47
BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear export. J Biol Chem (2002) 1.43
Is there more to BARD1 than BRCA1? Nat Rev Cancer (2006) 1.37
BARD1 participates with BRCA1 in homology-directed repair of chromosome breaks. Mol Cell Biol (2003) 1.34
Mechanisms of chromosome instability in cancers. Crit Rev Oncol Hematol (2006) 1.31
Cancer chromosomes in crisis. Nat Genet (2004) 1.30
The ubiquitin E3 ligase activity of BRCA1 and its biological functions. Cell Div (2008) 1.21
Identification of BARD1 as mediator between proapoptotic stress and p53-dependent apoptosis. Mol Cell (2001) 1.21
High proportion of recurrent germline mutations in the BRCA1 gene in breast and ovarian cancer patients from the Prague area. Breast Cancer Res (2005) 1.19
Loss of Bard1, the heterodimeric partner of the Brca1 tumor suppressor, results in early embryonic lethality and chromosomal instability. Mol Cell Biol (2003) 1.16
Distinct roles of BARD1 isoforms in mitosis: full-length BARD1 mediates Aurora B degradation, cancer-associated BARD1beta scaffolds Aurora B and BRCA2. Cancer Res (2009) 1.12
BARD1 regulates BRCA1 apoptotic function by a mechanism involving nuclear retention. Exp Cell Res (2004) 1.12
Common variation at BARD1 results in the expression of an oncogenic isoform that influences neuroblastoma susceptibility and oncogenicity. Cancer Res (2012) 1.09
Replication of neuroblastoma SNP association at the BARD1 locus in African-Americans. Cancer Epidemiol Biomarkers Prev (2012) 1.06
BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase. Oncogene (2005) 1.03
Cancer predisposing BARD1 mutations in breast-ovarian cancer families. Breast Cancer Res Treat (2011) 1.03
Expression of TRF1, TRF2, TIN2, TERT, KU70, and BRCA1 proteins is associated with telomere shortening and may contribute to multistage carcinogenesis of gastric cancer. J Cancer Res Clin Oncol (2010) 1.02
BRCA1 localization to the telomere and its loss from the telomere in response to DNA damage. J Biol Chem (2009) 1.02
Crystal structure of the BARD1 BRCT domains. Biochemistry (2007) 1.01
In vitro repression of Brca1-associated RING domain gene, Bard1, induces phenotypic changes in mammary epithelial cells. J Cell Biol (1998) 0.98
Nuclear-cytoplasmic translocation of BARD1 is linked to its apoptotic activity. Oncogene (2004) 0.98
Aberrant expression of BARD1 in breast and ovarian cancers with poor prognosis. Int J Cancer (2006) 0.98
Interaction of the EWS NH2 terminus with BARD1 links the Ewing's sarcoma gene to a common tumor suppressor pathway. Cancer Res (2002) 0.96
Oncogenic BARD1 isoforms expressed in gynecological cancers. Cancer Res (2007) 0.95
Development and characterization of a clinically useful animal model of epithelial ovarian cancer in the Fischer 344 rat. Am J Obstet Gynecol (1996) 0.95
Structural requirements for the BARD1 tumor suppressor in chromosomal stability and homology-directed DNA repair. J Biol Chem (2007) 0.95
Disruption of BRCA1 function results in telomere lengthening and increased anaphase bridge formation in immortalized cell lines. Genes Chromosomes Cancer (2006) 0.95
BARD1 expression predicts outcome in colon cancer. Clin Cancer Res (2011) 0.94
Role of the telomeric DNA-binding protein TRF2 in the stability of human chromosome ends. Bioessays (1998) 0.90
The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50. Biochemistry (2008) 0.89
Pericentromeric instability and spontaneous emergence of human neoacrocentric and minute chromosomes in the alternative pathway of telomere lengthening. Cancer Res (2008) 0.89
Chromosome instability in neoplasia: chaotic roots to continuous growth. Int J Biochem Cell Biol (2005) 0.89
BARD1 translocation to mitochondria correlates with Bax oligomerization, loss of mitochondrial membrane potential, and apoptosis. J Biol Chem (2007) 0.89
BARD1: an independent predictor of survival in non-small cell lung cancer. Int J Cancer (2011) 0.88
Negative feedback loop of BRCA1-BARD1 ubiquitin ligase on estrogen receptor alpha stability and activity antagonized by cancer-associated isoform of BARD1. Int J Biochem Cell Biol (2010) 0.88
Role played by BRCA1 in transcriptional regulation in response to therapy. Biochem Soc Trans (2007) 0.88
TIN2 stability is regulated by the E3 ligase Siah2. Mol Cell Biol (2011) 0.87
A truncated splice variant of human BARD1 that lacks the RING finger and ankyrin repeats. Cancer Lett (2006) 0.84
Identification of BARD1 splice-isoforms involved in human trophoblast invasion. Int J Biochem Cell Biol (2007) 0.84
BARD1 homozygous deletion, a possible alternative to BRCA1 mutation in basal breast cancer. Genes Chromosomes Cancer (2010) 0.83
Expression of oncogenic BARD1 isoforms affects colon cancer progression and correlates with clinical outcome. Br J Cancer (2012) 0.82
Crystal structure of the BARD1 ankyrin repeat domain and its functional consequences. J Biol Chem (2008) 0.81
Identification of novel alternatively spliced BRCA1-associated RING domain (BARD1) messenger RNAs in human peripheral blood lymphocytes and in sporadic breast cancer tissues. Genes Chromosomes Cancer (2007) 0.81
New concepts on BARD1: Regulator of BRCA pathways and beyond. Int J Biochem Cell Biol (2015) 0.81
BRCA1/2 mutations perturb telomere biology: characterization of structural and functional abnormalities in vitro and in vivo. Oncotarget (2016) 0.77
Cancer predisposing BARD1 mutations affect exon skipping and are associated with overexpression of specific BARD1 isoforms. Oncol Rep (2015) 0.76