Published in Mol Cell Biol on July 01, 2003
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The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis. Mol Cell Biol (2007) 2.07
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E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks. Proc Natl Acad Sci U S A (2008) 1.97
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Disruption of peripheral leptin signaling in mice results in hyperleptinemia without associated metabolic abnormalities. Endocrinology (2007) 1.73
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Human endothelium: target for aldosterone. Hypertension (2004) 1.61
BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II. Genes Dev (2005) 1.57
Potential role for ADAM15 in pathological neovascularization in mice. Mol Cell Biol (2003) 1.57
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BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear export. J Biol Chem (2002) 1.43
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BARD1 participates with BRCA1 in homology-directed repair of chromosome breaks. Mol Cell Biol (2003) 1.34
Ubiquitination and proteasomal degradation of the BRCA1 tumor suppressor is regulated during cell cycle progression. J Biol Chem (2004) 1.33
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CD44 variant isoforms promote metastasis formation by a tumor cell-matrix cross-talk that supports adhesion and apoptosis resistance. Mol Cancer Res (2009) 1.30
Diminished growth and enhanced glucose metabolism in triple knockout mice containing mutations of insulin-like growth factor binding protein-3, -4, and -5. Mol Endocrinol (2006) 1.29
Double-strand break repair by homologous recombination in primary mouse somatic cells requires BRCA1 but not the ATM kinase. Proc Natl Acad Sci U S A (2013) 1.27
The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression. Proc Natl Acad Sci U S A (2008) 1.25
Microtubule-dependent matrix metalloproteinase-2/matrix metalloproteinase-9 exocytosis: prerequisite in human melanoma cell invasion. Cancer Res (2004) 1.23
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iPSC-derived β cells model diabetes due to glucokinase deficiency. J Clin Invest (2013) 1.23
Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice. J Cell Biol (2012) 1.21
Activation of DSB processing requires phosphorylation of CtIP by ATR. Mol Cell (2012) 1.16
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Discordance in the histopathologic diagnosis of difficult melanocytic neoplasms in the clinical setting. J Cutan Pathol (2008) 1.13
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Homologous recombination DNA repair genes play a critical role in reprogramming to a pluripotent state. Cell Rep (2013) 1.07
Differential action of steroid hormones on human endothelium. J Cell Sci (2006) 1.06
Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice. Proc Natl Acad Sci U S A (2011) 1.03
Involvement of endothelial ephrin-B2 in adhesion and transmigration of EphB-receptor-expressing monocytes. J Cell Sci (2008) 1.00
The interaction between CtIP and BRCA1 is not essential for resection-mediated DNA repair or tumor suppression. J Cell Biol (2013) 1.00
A mouse model of uterine leiomyosarcoma. Am J Pathol (2004) 0.99
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The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function. Mol Cell Biol (2010) 0.97
Hypomethylating therapy in an aggressive stroma-rich model of pancreatic carcinoma. Cancer Res (2012) 0.97
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T-cell-specific deletion of Mof blocks their differentiation and results in genomic instability in mice. Mutagenesis (2013) 0.96
Interdependency of cell adhesion, force generation and extracellular proteolysis in matrix remodeling. J Cell Sci (2011) 0.95
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Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching. J Exp Med (2012) 0.95
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Ubiquitination and proteasome-mediated degradation of BRCA1 and BARD1 during steroidogenesis in human ovarian granulosa cells. Mol Endocrinol (2006) 0.93
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Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis. Development (2009) 0.90
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BRCA1 promotes the ubiquitination of PCNA and recruitment of translesion polymerases in response to replication blockade. Proc Natl Acad Sci U S A (2013) 0.88
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CtIP silencing as a novel mechanism of tamoxifen resistance in breast cancer. Mol Cancer Res (2007) 0.87
Inducible knockout of Twist1 in young and adult mice prolongs hair growth cycle and has mild effects on general health, supporting Twist1 as a preferential cancer target. Am J Pathol (2013) 0.86
2B4 engagement mediates rapid LFA-1 and actin-dependent NK cell adhesion to tumor cells as measured by single cell force spectroscopy. J Immunol (2011) 0.85
EphB4 promotes site-specific metastatic tumor cell dissemination by interacting with endothelial cell-expressed ephrinB2. Mol Cancer Res (2010) 0.84
CARMA1 is necessary for optimal T cell responses in a murine model of allergic asthma. J Immunol (2011) 0.84
Randomised controlled trial to determine the appropriate time to initiate peritoneal dialysis after insertion of catheter to minimise complications (Timely PD study). BMC Nephrol (2010) 0.83
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Damage-induced BRCA1 phosphorylation by Chk2 contributes to the timing of end resection. Cell Cycle (2015) 0.81
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The extracellular matrix remodeled: Interdependency of matrix proteolysis, cell adhesion, and force sensing. Commun Integr Biol (2012) 0.81
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Speed optimized influence matrix processing in inverse treatment planning tools. Phys Med Biol (2008) 0.80
Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1). Mamm Genome (2012) 0.79