Published in Nat Chem Biol on January 09, 2017
Opportunities and Challenges in RNA Structural Modeling and Design. Biophys J (2017) 0.75
The Long Non-Coding RNA MEG3 is an Epigenetic Determinant of Oncogenic Signaling in Functional Pancreatic Neuroendocrine Tumor Cells. Mol Cell Biol (2017) 0.75
Interpreting Reverse Transcriptase Termination and Mutation Events for Greater Insight into the Chemical Probing of RNA. Biochemistry (2017) 0.75
The human genome browser at UCSC. Genome Res (2002) 168.23
Gene action in the X-chromosome of the mouse (Mus musculus L.). Nature (1961) 23.98
Size-distribution analysis of macromolecules by sedimentation velocity ultracentrifugation and lamm equation modeling. Biophys J (2000) 21.93
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome. Science (2008) 13.79
Ensembl 2014. Nucleic Acids Res (2013) 12.62
The human XIST gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus. Cell (1992) 8.05
Long noncoding RNAs and human disease. Trends Cell Biol (2011) 7.59
The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell (1992) 6.26
The hallmarks of cancer: a long non-coding RNA point of view. RNA Biol (2012) 5.60
Chromosomal silencing and localization are mediated by different domains of Xist RNA. Nat Genet (2002) 5.51
A fast-acting reagent for accurate analysis of RNA secondary and tertiary structure by SHAPE chemistry. J Am Chem Soc (2007) 4.81
Epigenetic regulation by long noncoding RNAs. Science (2012) 4.74
Infernal 1.1: 100-fold faster RNA homology searches. Bioinformatics (2013) 4.16
Macromolecular size-and-shape distributions by sedimentation velocity analytical ultracentrifugation. Biophys J (2006) 4.06
The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3. Nature (2015) 3.60
In vivo genome-wide profiling of RNA secondary structure reveals novel regulatory features. Nature (2013) 3.28
Genome-wide probing of RNA structure reveals active unfolding of mRNA structures in vivo. Nature (2013) 3.00
Using an RNA secondary structure partition function to determine confidence in base pairs predicted by free energy minimization. RNA (2004) 2.86
Genome-wide measurement of RNA folding energies. Mol Cell (2012) 2.85
Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing. Science (2016) 2.72
Multiple knockout mouse models reveal lincRNAs are required for life and brain development. Elife (2013) 2.66
Genome-wide analysis of long noncoding RNA stability. Genome Res (2012) 2.49
SHAPE-directed RNA secondary structure prediction. Methods (2010) 2.40
2-D structure of the A region of Xist RNA and its implication for PRC2 association. PLoS Biol (2010) 2.30
Systematic discovery of Xist RNA binding proteins. Cell (2015) 2.26
Principles of RNA compaction: insights from the equilibrium folding pathway of the P4-P6 RNA domain in monovalent cations. J Mol Biol (2004) 1.90
Automated 3D structure composition for large RNAs. Nucleic Acids Res (2012) 1.85
Unique features of long non-coding RNA biogenesis and function. Nat Rev Genet (2015) 1.81
RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure. Cell (2016) 1.67
R2R--software to speed the depiction of aesthetic consensus RNA secondary structures. BMC Bioinformatics (2011) 1.60
Structural architecture of the human long non-coding RNA, steroid receptor RNA activator. Nucleic Acids Res (2012) 1.58
Long noncoding RNAs: fresh perspectives into the RNA world. Trends Biochem Sci (2013) 1.55
Characterization of the genomic Xist locus in rodents reveals conservation of overall gene structure and tandem repeats but rapid evolution of unique sequence. Genome Res (2001) 1.54
Folding of group II introns: a model system for large, multidomain RNAs? Trends Biochem Sci (2007) 1.45
Jarid2 Is Implicated in the Initial Xist-Induced Targeting of PRC2 to the Inactive X Chromosome. Mol Cell (2014) 1.41
High-throughput SHAPE and hydroxyl radical analysis of RNA structure and ribonucleoprotein assembly. Methods Enzymol (2009) 1.38
ATRX directs binding of PRC2 to Xist RNA and Polycomb targets. Cell (2014) 1.38
The Xist RNA A-repeat comprises a novel AUCG tetraloop fold and a platform for multimerization. RNA (2011) 1.26
An alternative route for the folding of large RNAs: apparent two-state folding by a group II intron ribozyme. J Mol Biol (2003) 1.24
A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing. Cell Rep (2015) 1.16
X-chromosome inactivation: new insights into cis and trans regulation. Curr Opin Genet Dev (2015) 1.14
HOTAIR forms an intricate and modular secondary structure. Mol Cell (2015) 1.08
Identification of Spen as a Crucial Factor for Xist Function through Forward Genetic Screening in Haploid Embryonic Stem Cells. Cell Rep (2015) 1.07
A NMR strategy to unambiguously distinguish nucleic acid hairpin and duplex conformations applied to a Xist RNA A-repeat. Nucleic Acids Res (2008) 1.05
Probing Xist RNA Structure in Cells Using Targeted Structure-Seq. PLoS Genet (2015) 0.98
RNA crosslinking methods. Methods Enzymol (2009) 0.93
Statistical analysis of SHAPE-directed RNA secondary structure modeling. Biochemistry (2013) 0.85
3S: shotgun secondary structure determination of long non-coding RNAs. Methods (2013) 0.82
Riboswitch folding: one at a time and step by step. RNA Biol (2008) 0.80
Native Purification and Analysis of Long RNAs. Methods Enzymol (2015) 0.77